Constant-temperature uniform mixing device for heating, disinfecting and sterilizing test sample

Abstract

The utility model belongs to the technical field of heating constant-temperature blending instruments, and particularly discloses a test sample heating, disinfecting and sterilizing constant-temperature blending device which comprises a shell, a blending platform deck and a tube seat, the blending platform deck is connected to the shell, the tube seat is connected to the top of the blending platform deck, a plurality of tube holes are formed in the tube seat, a heating unit and a blending unit are arranged in the shell, and the heating unit is connected with the blending unit. A top cover is arranged at the top of the uniform mixing platform deck, four screw rods are fixedly connected to the uniform mixing platform deck, each screw rod is in threaded connection with a nut, each nut abuts against the top cover, and a power source is arranged in the shell. According to the utility model, the sample tube is inserted into the tube hole of the tube seat, the top cover is downwards propped against the top of the sample tube, the nut is downwards screwed and propped against the top of the sample tube, a biological sample in the sample tube is uniformly mixed and heated through the uniform mixing unit and the heating unit, and the top cover plays a good role in sealing the top of the sample tube; the biological sample is prevented from ejecting the cover body of the sample tube in a heating state and splashing to pollute the environment and the interior of an instrument.

Description

Technical Field

[0001] The utility model relates to the technical field of constant temperature mixers, in particular to a constant temperature mixer for heating, disinfecting and sterilizing test samples. Background Art

[0002] Currently, many sectors and industries, including scientific research, agriculture, health, chemical engineering, and petroleum, require heating, disinfection, sterilization, and mixing of liquids containing specific pathogens or samples. For example, the agricultural sector requires pretreatment of samples such as blood, urine, secretions, plasma, and feces in test tubes through heating, disinfection, sterilization, and constant temperature mixing. Scientific research also requires pretreatment of different liquids, including samples and pretreated samples, in test tubes through mixing and heating. Pretreatment of biological samples involves disrupting tissue or cultured cells to release intracellular substances into a buffer solution, which is the first step in extracting intracellular proteins or nucleic acids. Currently, experiments often use a constant temperature water bath for heating, disinfection, cooling, and mixing of samples.

[0003] Chinese patent application number 201721854388.7 discloses a new constant temperature mixer, including an upper cover and a lower cover arranged at the bottom of the upper cover, a bottom plate is installed on the top of the lower cover and inside the upper cover, four support columns are evenly installed on the top of the bottom plate, shock-absorbing columns are provided on the top of the support columns, and the tops of the shock-absorbing columns are connected to the support plate, a DC motor is installed on the top of the bottom plate and on the inner sides of the four support columns, motor side plates are provided on both sides of the DC motor, a motor upper fixing plate is installed on the top of the DC motor, a bearing seat is provided on the support plate, a bearing is provided on the inner side of the bearing seat, an eccentric shaft is provided on the top of the DC motor, an eccentric block is installed on one side of the eccentric shaft, and a bearing is connected to the top of the eccentric shaft.

[0004] The transparent cover in the above patent is far away from the top of the sample tube. During the actual mixing and heating process of the sample tube, the gas in the sample tube will expand when the biological sample is heated, thereby pushing open the cover of the sample tube, causing liquid splashing, leading to cross-contamination of the sample, and affecting the unique components of the sample. At the same time, unknown pathogens in the biological sample will also cause contamination of the machine and the environment. If the transparent cover is not tightly closed, it is more likely to be pushed open, causing the biological sample to splash, contaminating the laboratory environment or splashing onto the operator, causing a biosafety accident. Utility Model Content

[0005] The purpose of the utility model is to provide a constant temperature mixing device for heating, disinfecting and sterilizing test samples, so as to solve the problem that when the sample tube is in a heated state, the biological sample in the sample tube will expand due to the heat and push open the cover of the sample tube or even the protective cover, thereby splashing and polluting the laboratory environment.

[0006] In order to achieve the above-mentioned purpose, the basic solution provided by the utility model is: a constant temperature mixing device for heating, disinfecting and sterilizing test samples, comprising a shell, a mixing platform and a tube holder, the mixing platform is connected to the shell, the tube holder is connected to the top of the mixing platform, a plurality of tube holes for inserting sample tubes are provided on the tube holder, a heating unit for heating the sample tubes and a mixing unit for mixing the samples are provided in the shell, a top cover is provided on the top of the mixing platform, four screws are fixedly connected to the mixing platform, a circular hole is provided on the top cover for the screw to pass through, each of the screws is threadedly connected to a nut, each of the nut is tightly pressed against the top cover, and a power supply for driving the mixing unit and the heating unit is provided in the shell.

[0007] The principle and beneficial effect of the utility model are as follows: the utility model unscrews the nut above the top cover, lifts the top cover, then inserts the sample tube into the tube hole of the tube holder, presses the top cover downward against the top of the sample tube, tightens the nut downward so that the bottom of the top cover presses against the top of the sample tube, starts the power supply, mixes and heats the biological sample in the sample tube respectively through the mixing unit and the heating unit; during the mixing and heating process, the top cover has a good sealing effect on the top of the sample tube, preventing the biological sample from easily pushing open the cover of the sample tube and splashing when heated.

[0008] Option 2, which is a preferred option of the basic option, wherein the heating unit includes a heat conducting plate and a heating film, wherein the heat conducting plate is fixed to the bottom of the mixing platform, the heating film is fixed to the heat conducting plate, and a heat insulating plate is connected to the side of the heating film away from the heat conducting plate, and the heat insulating plate is connected to the mixing unit;

[0009] By setting up a heating unit, the operator controls the heating of the heating film, which transfers the temperature to the heat conducting plate, thereby heating the mixing platform and the tube holder through the heat conducting plate. At the same time, the heat insulating plate can insulate the heating film, preventing the mixing unit from being affected by heat and affecting its normal operation.

[0010] Option three, which is a preferred option of the basic option, the mixing unit includes a motor, a fixed column and a slide rail, the motor is fixed in the housing, the output shaft of the motor is connected to a connecting plate, the connecting plate is fixed to an eccentric shaft, the slide rail is provided on the side of the heat insulation plate close to the motor, the end of the eccentric shaft is slidably connected to the slide rail, four support columns are fixed in the housing, each of the support columns is fixed to a spring, the free end of each spring is connected to a fixed column, and the fixed column is fixed to the heat insulation plate;

[0011] By setting up a mixing unit, when the motor is started, the output shaft of the motor drives the connecting plate and the eccentric shaft to rotate. When the eccentric shaft rotates, the center of gravity of the heat insulation plate, the mixing platform and the tube holder is shifted. The spring close to the eccentric shaft is in a stretched state, and the spring away from the stretched spring is in a compressed state. At this time, the mixing platform and the tube holder vibrate up and down, thereby achieving a mixing operation on the biological sample in the sample tube in the tube holder.

[0012] Option 4 is a preferred option of the basic option. The tube holes have three apertures, which can respectively accommodate 2ml, 5ml and 10ml sample tubes. By setting tube holes of different apertures, biological samples in sample tubes of different specifications can be heated and mixed at one time.

[0013] Option 5 is a preferred option of Option 4. The top cover is stepped, and the bottom of the top cover is in close contact with the top of the sample tube inserted into the tube hole. The stepped top cover can accommodate sample tubes of different heights and provide a more fitting cover.

[0014] Option six is ​​a preferred option of option two. A card block is fixed on the mixing platform, and a protective cover is inserted into the card block. By setting up the protective cover, firstly, it can indirectly protect the sample tube when it is heated and mixed, and secondly, when the mixing device is not used, the protective cover can prevent dust and impurities from entering the mixing platform or the tube holder.

[0015] Option seven is a preferred option of option three. A liquid crystal screen is provided on the shell; the temperature of the tube holder on the mixing platform and other information are displayed on the liquid crystal screen, which is convenient for operators to observe and record during operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is an exploded view of a constant temperature mixing device for heating, disinfecting and sterilizing test samples of the utility model;

[0017] Figure 2 This is an exploded view of a constant temperature mixing device for heating, disinfecting and sterilizing test samples of the utility model when the protective cover is not covered;

[0018] Figure 3 This is a three-dimensional diagram of the top cover of a constant temperature mixing device for heating, disinfecting and sterilizing test samples of the present utility model;

[0019] Figure 4 This is a front view of a constant temperature mixing device for heating, disinfecting and sterilizing test samples of the utility model when the protective cover is not covered;

[0020] Figure 5 yes Figure 4 Cross-sectional view at AA in the middle;

[0021] Figure 6 yes Figure 4A top view of

[0022] Figure 7 The utility model is a three-dimensional diagram of the connection between a mixing unit and a heating unit in a constant temperature mixing device for heating, disinfecting and sterilizing test samples. DETAILED DESCRIPTION

[0023] The present invention is further described in detail below through specific implementation methods:

[0024] The figure marks in the drawings of the specification include: 1. mixing platform; 2. tube seat; 3. top cover; 4. screw; 5. nut; 6. tube hole; 7. heat conduction plate; 8. heating film; 9. heat insulation plate; 10. slide rail; 11. eccentric shaft; 12. connecting plate; 13. motor; 14. spring; 15. fixing column; 16. support column; 17. power supply; 18. LCD screen; 19. shell; 20. protective cover; 21. sample tube; 22. block.

[0025] like Figures 1 to 7 As shown: A constant temperature mixing device for heating, disinfecting and sterilizing test samples, including a shell 19, a mixing platform 1 and a tube holder 2, the mixing platform 1 is fixedly connected to the shell 19, the tube holder 2 is fixedly connected to the top of the mixing platform 1, and a plurality of tube holes 6 are opened on the tube holder 2. The specifications of the plurality of tube holes 6 are provided in three types. The tube holes 6 are used to insert sample tubes 21 to be heated and mixed. The three specifications of the tube holes 6 can respectively carry sample tubes 21 with a capacity of 2ml, 5ml and 10ml. The top of the tube holder 2 is fixedly connected with four screws. Rod 4, the top of the tube holder 2 is overlapped with a top cover 3, and four round holes are opened on the top cover 3 for the screw rod 4 to pass through. Each screw rod 4 is threadedly connected with a nut 5. The top cover 3 is stepped. When the top cover 3 is covered on the top of the tube holder 2, the nut 5 is hung down and pressed against the top of the top cover 3, so that the top cover 3 can respectively cover the tops of sample tubes 21 of different heights inserted in the tube holder 2; the top of the mixing platform 1 is fixedly connected with a block 22, and the block 22 is plugged with a protective cover 20, and the bottom end of the protective cover 20 is against the mixing platform 1.

[0026] A heating unit and a mixing unit are provided in the shell 19. The heating unit includes a heat conducting plate 7 and a heating film 8. The mixing unit includes a motor 13, a fixed column 15 and a slide rail 10. The heat conducting plate 7 is fixedly connected to the bottom of the mixing platform 1. The heat conducting plate 7 is fixedly connected to the heating film 8. The bottom of the heating film 8 is fixedly connected with a heat insulation plate 9. There are four fixed columns 15. Each fixed column 15 is fixedly connected to the bottom of the heat insulation plate 9. The fixed columns 15 are respectively provided near the four corners of the heat conducting plate 7. Four support columns 16 are fixedly connected to the shell 19. Each support column 16 is located directly below the fixed column 15. A spring 14 is fixedly connected between each fixed column 15 and the support column 16.

[0027] Motor 13 is fixedly connected to housing 19. The output shaft of motor 13 is fixedly connected to connecting plate 12, which is fixedly connected to eccentric shaft 11. Slide rail 10 is provided at the bottom of heat shield 9. Slide rail 10 has a circular cross-section. One end of eccentric shaft 11 extends toward heat shield 9 and is slidably connected to slide rail 10. The end of eccentric shaft 11 is hemispherical. LCD screen 18 is fixedly connected to housing 19. Power supply 17 is housed within housing 19 to provide power to heater 8, motor 13, and LCD screen 18.

[0028] The implementation method of this embodiment is as follows: when in use, the power supply 17 is turned on so that the device can be used normally, the nut 5 on the top cover 3 is first removed, and the top cover 3 is moved upward. The operator places the sample tube 21 containing the biological sample to be mixed and heated into the tube hole 6 in the tube holder 2, and then presses the top cover 3 downward against the top of the sample tube 21 and tightens the nut 5 downward so that the bottom of the top cover 3 can be pressed against the top of the sample tube 21, pressing the sample tube 21 to prevent the biological sample from splashing during mixing.

[0029] The operator controls the heating film 8 to heat up and starts the motor 13; when the motor 13 rotates, the output shaft drives the connecting plate 12 and the eccentric shaft 11 to rotate, and the eccentric shaft 11 slides in the slide rail 10 at the bottom of the thermal insulation plate 9. When the eccentric shaft 11 rotates, the spring 14 on the side near the eccentric shaft 11 is in a stretched state, and the spring 14 on the farther side of the stretched state is in a compressed state. The eccentric shaft 11 drives the thermal insulation plate 9, the heating film 8, the heat conducting plate 7, the mixing base, the tube holder 2 and the sample tube 21 to vibrate up and down to complete the mixing operation. The heating film 8 transfers the heat to the heat conducting plate 7, and then transfers the temperature to the mixing base and the tube holder 2 through the heat conducting plate 7, so that the sample tube 21 in the tube holder 2 is heated. When heated to the target temperature, the heating film 8 is controlled to stop heating and maintain it at a constant temperature, so that the sample tube 21 can be stored at a constant temperature. Finally, the biological sample can be mixed, heated and kept at a constant temperature at the same time under the device. At the same time, during the heating and mixing process, the biological sample will not splash outside the device under the action of the top cover 3.

[0030] The above is only an embodiment of the present invention, and the commonly known specific structures and characteristics of the scheme are not described in detail here. It should be pointed out that for those skilled in the art, several modifications and improvements can be made without departing from the structure of the present invention, and these should also be regarded as the scope of protection of the present invention. These will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection claimed by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A constant temperature mixing device for heating, disinfecting and sterilizing test samples, characterized in that: The mixing platform (1) comprises a shell (19), a mixing platform (1) and a tube holder (2), wherein the mixing platform (1) is connected to the shell (19), the tube holder (2) is connected to the top of the mixing platform (1), a plurality of tube holes (6) for inserting sample tubes (21) are provided on the tube holder (2), a heating unit for heating the sample tubes (21) and a mixing unit for mixing the samples are provided in the shell (19), a top cover (3) is provided on the top of the mixing platform (1), four screw rods (4) are fixedly connected to the mixing platform (1), a round hole is provided on the top cover (3) for the screw rods (4) to pass through, each of the screw rods (4) is threadedly connected to a nut (5), and each of the nut (5) is tightly pressed against the top cover (3), and a power supply (17) for driving the mixing unit and the heating unit is provided in the shell (19).

2. A constant temperature mixing device for heating, disinfecting and sterilizing test samples according to claim 1, characterized in that: The heating unit comprises a heat conducting plate (7) and a heating film (8), wherein the heat conducting plate (7) is fixedly connected to the bottom of the mixing platform (1), and the heating film (8) is fixedly connected to the heat conducting plate (7). A heat insulating plate (9) is connected to the side of the heating film (8) away from the heat conducting plate (7), and the heat insulating plate (9) is connected to the mixing unit.

3. A constant temperature mixing device for heating, disinfecting and sterilizing test samples according to claim 1, characterized in that: The mixing unit comprises a motor (13), a fixing column (15) and a slide rail (10); the motor (13) is fixedly connected in a housing (19); the output shaft of the motor (13) is connected to a connecting plate (12); the connecting plate (12) is fixedly connected to an eccentric shaft (11); the slide rail (10) is arranged on a side of the heat insulation plate (9) close to the motor (13); the end of the eccentric shaft (11) is slidably connected to the slide rail (10); four supporting columns (16) are fixedly connected in the housing (19); each of the supporting columns (16) is fixedly connected to a spring (14); the free end of each of the springs (14) is connected to a fixing column (15); and the fixing column (15) is fixedly connected to the heat insulation plate (9).

4. A constant temperature mixing device for heating, disinfecting and sterilizing test samples according to claim 1, characterized in that: The tube hole (6) has three apertures, and the three apertures of the tube hole (6) can carry sample tubes (21) of 2 ml, 5 ml and 10 ml respectively.

5. A constant temperature mixing device for heating, disinfecting and sterilizing test samples according to claim 4, characterized in that: The top cover (3) is in a stepped shape, and the bottom of the top cover (3) is in close contact with the top of the sample tube (21) inserted into the tube hole (6).

6. A constant temperature mixing device for heating, disinfecting and sterilizing test samples according to claim 2, characterized in that: A clamping block (22) is fixedly connected to the mixing platform (1), and a protective cover (20) is inserted into the clamping block (22).

7. A constant temperature mixing device for heating, disinfecting and sterilizing test samples according to claim 3, characterized in that: The housing (19) is provided with a liquid crystal screen (18).

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