Cell test tube centrifugal device

Abstract

The utility model relates to the technical field of medical instruments, in particular to a cell test tube centrifugal device. The centrifugal machine comprises a centrifugal machine body, a protective cover and a rotary centrifugal cylinder, a clamping and fixing mechanism is assembled in the rotary centrifugal cylinder, a centrifugal protective mechanism is assembled between the centrifugal machine body and the protective cover, and the clamping and fixing mechanism comprises a clamping plate, a threaded rod, a first bearing, a butterfly knob and a clamping arc surface. Through the structural design of the clamping and fixing mechanism, the device realizes the adjustment of the distance between two clamping plates by rotating a butterfly knob so as to clamp and fix test tubes with different specifications and diameters; through the structural design of the centrifugal protection mechanism, protection during centrifugation is achieved through cooperation of a matching head and two telescopic heads; and through the structural design of the centrifugal mechanism, the centrifugal separation of the cells in the test tube is realized by starting a motor to realize the rotation of a rotary centrifugal barrel in the centrifugal machine body.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a cell test tube centrifuge device. Background Art

[0002] A cell centrifuge, also known as a centrifuge, is a device specially designed for separating, enriching, purifying or grading cells in a cell suspension. It generates centrifugal force through high-speed rotation, so that different components in the cell suspension are separated due to differences in mass and volume; this technology has the advantages of high speed, high separation efficiency and low damage, making the cell centrifuge have a wide range of application value in biomedical research and production practice; in the cell centrifuge, this centrifugal force allows cells, organelles or DNA / RNA particles in the cell suspension to be separated according to different masses and volumes; in the cell culture process, the cell centrifuge can be used to wash and enrich cells to improve the efficiency and quality of cell culture; in blood separation, the cell centrifuge can be used to separate components such as plasma, white blood cells, red blood cells, platelets, etc., providing important support for clinical diagnosis and treatment; with the continuous advancement and innovation of technology, the cell centrifuge will play a more important role in the future biomedical field.

[0003] For example, patent CN219156854U discloses a cell centrifugal filtration separation device, which centrifuges the separation tube so that the sample inside it passes through the filter membrane inside it under the action of centrifugal force, thereby completing the separation of target cells. In this way, the sample moves with the separation tube, and the inside is always in a flowing state, which is not easy to cause clogging of the micropores on the surface of the filter membrane. In addition, in this separation method, the sample is always located in the separation tube and does not come into contact with the outside air, which is not easy to contaminate the sample and affect subsequent observations.

[0004] When using the above technology, it was found that the following technical problems exist in the prior art: the existing cell centrifugal filtration separation device cannot clamp test tubes of different diameters for centrifugal separation according to the test tube specifications, and the existing centrifugal device has no protective device. The centrifugal separation device moves at a very high speed, and without protection, it is easy to be dangerous and cause safety accidents. Therefore, there is room for improvement in the existing cell centrifugal filtration separation device. To this end, we designed a cell test tube centrifugal device to provide another technical solution to the above technical problems. Utility Model Content

[0005] Based on this, it is necessary to provide a cell test tube centrifuge device to solve the technical problems of clamping test tubes of different specifications and diameters and protecting them during centrifugal separation in response to the above technical problems.

[0006] In order to solve the above technical problems, the utility model adopts the following technical solutions:

[0007] A cell test tube centrifuge device comprises a centrifuge body, a protective cover and a rotating centrifuge cylinder, wherein the top of the centrifuge body is equipped with a protective cover, the interior of the centrifuge body is equipped with a rotating centrifuge cylinder, the interior of the rotating centrifuge cylinder is equipped with a clamping and fixing mechanism, and a centrifuge protection mechanism is installed between the centrifuge body and the protective cover;

[0008] The clamping and fixing mechanism includes a clamping plate, a threaded rod, a first bearing, a butterfly knob and a clamping arc surface. The rotating centrifugal cylinder is internally slidably connected to two clamping plates, and the internal threads of the two clamping plates are connected to a threaded rod. The threads at both ends of the threaded rod have opposite rotation directions. Two first bearings are fixed to the outside of the threaded rod, and the two first bearings are fixed to the rotating centrifugal cylinder. A butterfly knob is fixed to one end of the threaded rod. A clamping arc surface for clamping is provided on the side where the two clamping plates are close to each other, and a plurality of clamping and fixing mechanisms are evenly distributed inside the rotating centrifugal cylinder.

[0009] Preferably, the centrifugal protection mechanism includes an opening and closing base, a rotating shaft, a mounting block, a matching head, a matching block, a telescopic head, a limiting disk and a spring. An opening and closing base is fixed to one end of the top of the centrifuge body. The opening and closing base is rotatably connected to the inside of the base. The rotating shaft and the protective cover are rotatably connected. A mounting block is fixed to one end of the protective cover. A matching head is fixed to the bottom of the mounting block. A matching block is fixed to one end of the centrifuge body. Two telescopic heads are slidably connected to the inside of the matching block. A limiting disk is fixed to one end of the telescopic head. The limiting disk and the matching block are also slidably connected. A spring is slidably connected to one side of the limiting disk and located inside the matching block. The two telescopic heads and the matching head are slidably connected.

[0010] Preferably, a centrifugal mechanism is installed between the centrifuge body and the rotating centrifugal cylinder, and the centrifugal mechanism includes a motor, a driving bevel gear, a driven bevel gear, a cylinder, and a second bearing. A motor is fixed to one end of the interior of the centrifuge body, a driving bevel gear is fixed to the power output end of the motor, the driving bevel gear is meshedly connected to the outside of the driving bevel gear, a cylinder is fixed to the inside of the driven bevel gear, a second bearing is fixed to the bottom of the cylinder, the second bearing is fixed to the centrifuge body, and the top of the cylinder is fixed to the rotating centrifugal cylinder.

[0011] Preferably, a plurality of round shafts are evenly distributed and fixed inside the centrifuge body, a rotating wheel is fixed outside the round shaft, and the rotating wheel is rotatably connected to the rotating centrifuge cylinder.

[0012] Preferably, a controller is fixed at one end of the centrifuge body, a display screen is fixed at the top of one side of the controller, a control switch is fixed at one end of one side of the controller and below the display screen, a speed control knob is fixed at the other end of one side of the controller and below the display screen, and the motor and the speed control knob are electrically connected.

[0013] Preferably, a groove is formed at one end of the protective cover.

[0014] Preferably, a plurality of floor pads are evenly distributed and fixed on the bottom of the centrifuge body, and anti-slip patterns are formed on the bottom of the floor pads.

[0015] It can be seen without a doubt that the above-mentioned technical solution of the present application can definitely solve the technical problem to be solved by the present application.

[0016] At the same time, through the above technical solutions, the utility model has at least the following beneficial effects:

[0017] 1. The utility model adopts the structural design of the clamping and fixing mechanism, so that the device can adjust the distance between the two clamping plates by rotating the butterfly knob to clamp and fix test tubes of different specifications and diameters, thereby improving the flexibility of clamping and fixing of the cell test tube centrifugal device.

[0018] 2. The utility model adopts the structural design of the centrifugal protection mechanism, so that the device can achieve protection during centrifugation through the cooperation between the matching head and the two telescopic heads, thereby improving the safety of the cell test tube centrifuge device.

[0019] 3. The utility model uses the structural design of the centrifugal mechanism to enable the device to realize the rotation of the rotating centrifuge cylinder inside the centrifuge body by starting the motor to achieve centrifugal separation of cells in the test tube, thereby improving the practicality of the cell test tube centrifuge device. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0021] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0022] Figure 2 This is a schematic diagram of the connection structure of the centrifuge body, the protective cover and the rotating centrifugal cylinder of the utility model;

[0023] Figure 3 This is a schematic diagram of the cross-sectional connection structure of the rotary centrifugal cylinder of the utility model;

[0024] Figure 4 It is a partial enlarged structural schematic diagram of the utility model;

[0025] Figure 5 It is a schematic diagram of the cross-sectional connection structure of the protective cover of the utility model;

[0026] Figure 6 This is a schematic diagram of the connection structure between the centrifuge body and the protective cover of the utility model;

[0027] Figure 7 It is a partial enlarged structural schematic diagram of the utility model;

[0028] Figure 8 It is a schematic diagram of the cross-sectional connection structure of the centrifuge body of the utility model.

[0029] In the figure: 1. centrifuge body; 2. protective cover; 3. rotating centrifuge cylinder; 4. clamping plate; 5. threaded rod; 6. first bearing; 7. butterfly knob; 8. clamping arc surface; 9. opening and closing base; 10. rotating shaft; 11. mounting block; 12. matching head; 13. matching block; 14. telescopic head; 15. limit plate; 16. spring; 17. motor; 18. driving bevel gear; 19. driven bevel gear; 20. cylinder; 21. second bearing; 22. round shaft rod; 23. rotating wheel; 24. controller; 25. display screen; 26. control switch; 27. speed knob; 28. groove; 29. ​​floor mat; 30. anti-slip texture. DETAILED DESCRIPTION

[0030] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0031] In order to enable those skilled in the art to better understand the solution of the utility model, the technical solution in the embodiments of the utility model will be clearly and completely described below in conjunction with the accompanying drawings.

[0032] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features and technical solutions in the embodiments may be combined with each other.

[0033] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0034] Embodiment 1

[0035] Reference Figure 1 - Figure 8 A cell test tube centrifuge device comprises a centrifuge body 1, a protective cover 2 and a rotating centrifuge cylinder 3. The top of the centrifuge body 1 is equipped with the protective cover 2, the inside of the centrifuge body 1 is equipped with the rotating centrifuge cylinder 3, the inside of the rotating centrifuge cylinder 3 is equipped with a clamping and fixing mechanism, and a centrifuge protection mechanism is installed between the centrifuge body 1 and the protective cover 2;

[0036] The clamping and fixing mechanism comprises a clamping plate 4, a threaded rod 5, a first bearing 6, a butterfly knob 7 and a clamping arc surface 8. Two clamping plates 4 are slidably connected inside the rotating centrifugal cylinder 3. The internal threads of the two clamping plates 4 are connected to a threaded rod 5. The threads at both ends of the threaded rod 5 have opposite rotation directions. Two first bearings 6 are fixed to the outside of the threaded rod 5. The two first bearings 6 are fixed to the rotating centrifugal cylinder 3. A butterfly knob 7 is fixed to one end of the threaded rod 5. A clamping arc surface 8 for clamping is provided on one side of the two clamping plates 4 close to each other. Multiple groups of clamping and fixing mechanisms are evenly distributed inside the rotating centrifugal cylinder 3. When test tubes of different specifications and diameters are to be clamped and fixed, the butterfly knob 7 is rotated, and the butterfly knob 7 drives the distance between the two clamping plates 4 to adjust, so that the clamping and fixing of test tubes of different specifications and diameters can be achieved.

[0037] A centrifugal mechanism is arranged between the centrifuge body 1 and the rotating centrifugal cylinder 3, and the centrifugal mechanism comprises a motor 17, a driving bevel gear 18, a driven bevel gear 19, a cylinder 20, and a second bearing 21. The motor 17 is fixed to one end of the interior of the centrifuge body 1, and the driving bevel gear 18 is fixed to the power output end of the motor 17, and the driven bevel gear 19 is meshedly connected to the exterior of the driving bevel gear 18, and the cylinder 20 is fixed to the interior of the driven bevel gear 19, and the second bearing 21 is fixed to the bottom of the cylinder 20, and the second bearing 21 is fixed to the centrifuge body 1, and the top of the cylinder 20 is fixed to the rotating centrifugal cylinder 3; when the cells in the test tube are to be centrifuged, the motor 17 is started, and the power output end of the motor 17 drives the driving bevel gear 18 to rotate, the driving bevel gear 18 drives the driven bevel gear 19 to rotate, the driven bevel gear 19 drives the cylinder 20 to rotate, and the cylinder 20 drives the rotating centrifugal cylinder 3 to rotate, so that the test tube clamped and fixed inside the rotating centrifugal cylinder 3 can be centrifuged;

[0038] A plurality of round shafts 22 are evenly distributed and fixed inside the centrifuge body 1, and a rotating wheel 23 is fixed outside the round shaft 22, and the rotating wheel 23 is rotatably connected to the rotating centrifuge cylinder 3; the arrangement of the round shaft 22 and the rotating wheel 23 reduces the resistance when the rotating centrifuge cylinder 3 rotates, and the operation is relatively stable and reliable, so that the centrifugal movement of the cell test tube centrifuge device is stable, smooth and efficient;

[0039] A controller 24 is fixed at one end of the centrifuge body 1, a display screen 25 is fixed at the top of one side of the controller 24, a control switch 26 is fixed at one end of one side of the controller 24 and below the display screen 25, a speed knob 27 is fixed at the other end of one side of the controller 24 and below the display screen 25, and the motor 17 and the speed knob 27 are electrically connected; the device can be turned on conveniently by setting the control switch 26, and the speed knob 27 can be conveniently selected according to the needs through the setting of the speed knob 27, and the specific value of the adjustment speed can be intuitively seen through the setting of the display screen 25, so that it is convenient to master and control according to the needs;

[0040] A plurality of floor pads 29 are evenly distributed and fixed on the bottom of the centrifuge body 1, and anti-skid patterns 30 are provided on the bottom of the floor pads 29. The arrangement of the floor pads 29 and the anti-skid patterns 30 ensures that the cell test tube centrifuge device is stable when placed and runs smoothly, thereby preventing the device from being disturbed by the force of the device during operation, which would affect the stable operation of the cell test tube centrifuge device.

[0041] Embodiment 2

[0042] Reference Figure 3 and Figure 4, a cell test tube centrifuge device, the centrifugal protection mechanism includes an opening and closing base 9, a rotating shaft 10, a mounting block 11, a matching head 12, a matching block 13, a telescopic head 14, a limiting disk 15 and a spring 16, an opening and closing base 9 is fixed at one end of the top of the centrifuge body 1, the internal rotation connection of the opening and closing base 9 is connected with the rotating shaft 10, the rotating shaft 10 and the protective cover 2 are rotatably connected, one end of the protective cover 2 is fixed with a mounting block 11, the bottom of the mounting block 11 is fixed with a matching head 12, one end of the centrifuge body 1 is fixed with a matching block 13, two telescopic heads 14 are slidably connected inside the matching block 13, one end of the telescopic head 14 is fixed with a limiting disk 15, the limiting disk 15 and the matching block 13 are also slidably connected, one side of the limiting disk 15 and located inside the matching block 13 are slidably connected with a spring 16, the two telescopic heads 14 and the matching head 12 are slidably connected; a groove 28 is provided at one end of the protective cover 2; the setting of the groove 28 makes the centrifuge body 1 and the protection cover 2 rotate. When the protective cover 2 is opened and closed manually, there is a force point, which facilitates the opening and closing of the centrifuge body 1 and the protective cover 2; when the cell test tube centrifuge device is to be centrifugally protected, the finger is put into the groove 28 and pulled, the protective cover 2 rotates around the rotating shaft 10, the protective cover 2 drives the mounting block 11, and the mounting block 11 drives the matching head 12 to rotate. When the matching head 12 contacts the two telescopic heads 14, the two telescopic heads 14 slide inside the matching block 13, and the telescopic head 14 drives the limiting plate 15. The limiting plate 15 is forced to squeeze the spring 16, and the spring 16 is forced to shrink, and the telescopic head 14 slides into the matching block 13. When the big head at one end of the matching head 12 passes, the spring 16 rebounds, and the spring 16 drives the limiting plate 15. The limiting plate 15 drives the telescopic head 14 to slide out of the matching block 13, so as to realize the position limitation of the matching head 12, and the centrifuge body 1 and the protective cover 2 can be closed to realize protection when the cell test tube is centrifuged.

[0043] The use process of a cell test tube centrifuge device provided by the utility model is as follows:

[0044] When test tubes of different diameters need to be clamped and fixed, the two clamping plates 4 are slidably connected to the rotating centrifugal cylinder 3, the two clamping plates 4 are threadedly connected to the threaded rod 5, the threads at both ends of the threaded rod 5 are rotated in opposite directions, the butterfly knob 7 is fixed to the threaded rod 5, and then the butterfly knob 7 is rotated, and the butterfly knob 7 drives the distance between the two clamping plates 4 to adjust, so that test tubes of different diameters can be clamped and fixed;

[0045] When the cell test tube centrifuge device is to be centrifuged and protected, since the centrifuge body 1 and the opening and closing base 9 are fixed, the opening and closing base 9 and the rotating shaft 10 are rotatably connected, the rotating shaft 10 and the protective cover 2 are rotatably connected, the protective cover 2 and the mounting block 11 are fixed, the mounting block 11 and the matching head 12 are fixed, the matching head 12 and the telescopic head 14 are slidably connected, the telescopic head 14 and the limiting plate 15 are fixed, and the telescopic head 14 and the limiting plate 15 are both slidably connected to the matching block 13, and then a finger is put into the groove 28 to pull, the protective cover 2 rotates around the rotating shaft 10, the protective cover 2 drives the mounting block 11, and the mounting block 11 drives the matching head 12 to rotate When the matching head 12 contacts the two telescopic heads 14, the two telescopic heads 14 slide inside the matching block 13, and the telescopic head 14 drives the limiting plate 15. The limiting plate 15 is forced to squeeze the spring 16. The spring 16 is forced to shrink, and the telescopic head 14 slides into the matching block 13. When the large head at one end of the matching head 12 passes, the spring 16 rebounds, and the spring 16 drives the limiting plate 15. The limiting plate 15 drives the telescopic head 14 to slide out of the matching block 13, thus realizing the position limitation of the matching head 12, and the centrifuge body 1 and the protective cover 2 can be closed to realize protection when the cell test tube is centrifuged;

[0046] When the cells in the test tube are to be centrifuged, since the motor 17 is fixed to the centrifuge body 1, the motor 17 is fixed to the driving bevel gear 18, the driving bevel gear 18 is meshed with the driven bevel gear 19, the driven bevel gear 19 is fixed to the cylinder 20, the cylinder 20 is fixed to the rotating centrifugal cylinder 3, and then the motor 17 is started, the power output end of the motor 17 drives the driving bevel gear 18 to rotate, the driving bevel gear 18 drives the driven bevel gear 19 to rotate, the driven bevel gear 19 drives the cylinder 20 to rotate, and the cylinder 20 drives the rotating centrifugal cylinder 3 to rotate, so that the test tube clamped and fixed inside the rotating centrifugal cylinder 3 can be centrifuged;

[0047] The preferred embodiments of the utility model disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the utility model to only specific implementation methods. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the utility model, so that technicians in the relevant technical field can well understand and use the utility model. The utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A cell test tube centrifuge device, characterized in that: The centrifuge comprises a centrifuge body (1), a protective cover (2) and a rotating centrifuge cylinder (3); the top of the centrifuge body (1) is equipped with the protective cover (2); the interior of the centrifuge body (1) is equipped with a rotating centrifuge cylinder (3); the interior of the rotating centrifuge cylinder (3) is equipped with a clamping and fixing mechanism; and a centrifuge protection mechanism is installed between the centrifuge body (1) and the protective cover (2); The clamping and fixing mechanism comprises a clamping plate (4), a threaded rod (5), a first bearing (6), a butterfly knob (7) and a clamping arc surface (8); the interior of the rotating centrifugal cylinder (3) is slidably connected to two clamping plates (4); the interior of the two clamping plates (4) is threadedly connected to a threaded rod (5); the threads at both ends of the threaded rod (5) have opposite rotation directions; the exterior of the threaded rod (5) is fixed with two first bearings (6); the two first bearings (6) are both fixed to the rotating centrifugal cylinder (3); a butterfly knob (7) is fixed to one end of the threaded rod (5); a clamping arc surface (8) for clamping is provided on the side where the two clamping plates (4) are close to each other; and a plurality of clamping and fixing mechanisms are evenly distributed inside the rotating centrifugal cylinder (3).

2. A cell test tube centrifuge device according to claim 1, characterized in that: The centrifugal protection mechanism comprises an opening and closing base (9), a rotating shaft (10), a mounting block (11), a matching head (12), a matching block (13), a telescopic head (14), a limiting plate (15) and a spring (16); an opening and closing base (9) is fixed to one end of the top of the centrifuge body (1); a rotating shaft (10) is rotatably connected inside the opening and closing base (9); the rotating shaft (10) and the protection cover (2) are rotatably connected; a mounting block (11) is fixed to one end of the protection cover (2); and the mounting block (11) is ) is fixed with a mating head (12) at the bottom, a mating block (13) is fixed at one end of the centrifuge body (1), two telescopic heads (14) are slidably connected inside the mating block (13), a limiting disk (15) is fixed at one end of the telescopic head (14), the limiting disk (15) and the mating block (13) are also slidably connected, a spring (16) is slidably connected on one side of the limiting disk (15) and located inside the mating block (13), and the two telescopic heads (14) and the mating head (12) are slidably connected.

3. A cell test tube centrifuge device according to claim 1, characterized in that: A centrifugal mechanism is arranged between the centrifuge body (1) and the rotating centrifugal cylinder (3), and the centrifugal mechanism comprises a motor (17), a driving bevel gear (18), a driven bevel gear (19), a cylinder (20), and a second bearing (21). The motor (17) is fixed to one end of the interior of the centrifuge body (1), the driving bevel gear (18) is fixed to the power output end of the motor (17), the driven bevel gear (19) is meshedly connected to the exterior of the driving bevel gear (18), the cylinder (20) is fixed to the interior of the driven bevel gear (19), the second bearing (21) is fixed to the bottom of the cylinder (20), the second bearing (21) is fixed to the centrifuge body (1), and the top of the cylinder (20) is fixed to the rotating centrifugal cylinder (3).

4. A cell test tube centrifuge device according to claim 3, characterized in that: A plurality of round shafts (22) are evenly distributed and fixed inside the centrifuge body (1), a rotating wheel (23) is fixed outside the round shaft (22), and the rotating wheel (23) is rotatably connected to the rotating centrifuge cylinder (3).

5. A cell test tube centrifuge device according to claim 3, characterized in that: A controller (24) is fixed at one end of the centrifuge body (1), a display screen (25) is fixed at the top of one side of the controller (24), a control switch (26) is fixed at one end of one side of the controller (24) and below the display screen (25), a speed control knob (27) is fixed at the other end of one side of the controller (24) and below the display screen (25), and the motor (17) and the speed control knob (27) are electrically connected.

6. A cell test tube centrifuge device according to claim 1, characterized in that: A groove (28) is formed at one end of the protective cover (2).

7. A cell test tube centrifuge device according to claim 1, characterized in that: A plurality of floor pads (29) are evenly distributed and fixed on the bottom of the centrifuge body (1), and anti-slip patterns (30) are provided on the bottom of the floor pads (29).

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