Adapter for maintaining long-time low-temperature state of perforated plate

By designing an adapter made of solid aluminum alloy and combining it with a buckle fixing structure, the problem that existing technology cannot maintain the low temperature state of the multi-well plate for a long time is solved, achieving rapid cooling and long-term low temperature state of the multi-well plate, and prolonging cell activity. time, improving the accuracy of detection results.

CN222393947UActive Publication Date: 2025-01-24SUZHOU KANGWEIXUN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420684717.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-07
Publication Date
2025-01-24
Estimated Expiration
2034-04-07

AI Technical Summary

Technical Problem

The existing flow cytometer multi-well plate loaders cannot maintain the low temperature state of cells in the multi-well plate for a long time by pre-freezing or putting in ice, resulting in active cell metabolism and affecting the detection results.

Method used

An adapter is designed, which includes an adapter body made of solid aluminum alloy and a buckle fixing structure. It can be quickly cooled by placing it in a refrigerator or ice bath, and the porous plate can be stably installed through the buckle fixing structure to ensure a long-term low temperature state.

Benefits of technology

The rapid cooling of porous boards and the maintenance of long -term low temperature state, extending the activity time of cells, and improving the accuracy of the test results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an adapter for maintaining a long-time low-temperature state of a perforated plate, which belongs to the technical field of biological application, and comprises an adapter main body and a buckle fixing structure, the adapter main body is a solid metal block, and a rectangular perforated plate mounting groove is formed in the upper part of the solid metal block; the buckle fixing structure comprises spring buckles and fixing screws, and the spring buckles are installed on a set of long edges and short edges of the perforated plate installation groove of the adapter body through the fixing screws. The adapter is simple in structure and convenient to operate, is made of solid aluminum, can be put into a refrigerator or quickly cooled through ice bath, is suitable for keeping low temperature for a long time, ensures the stability of the perforated plate after being mounted, is wear-resistant and durable, and prolongs the service life of the adapter.
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Description

Technical Field

[0001] The utility model relates to the technical field of biological applications, in particular to an adapter for maintaining a multi-well plate in a low temperature state for a long time. Background Art

[0002] Flow cytometry measures cells or particles in motion and can provide statistically significant single cell, particle or aggregate measurement data in a short period of time. At present, the development of flow cytometry technology has become an indispensable technology in many fields such as biological research, new drug research, and medical diagnosis. As these fields become more dependent on flow cytometry, higher requirements are also placed on high throughput and high accuracy of flow cytometry results.

[0003] However, high throughput and high accuracy require a trade-off in some cases. High throughput means a large number of samples and a long time required. In addition to technical requirements for equipment and personnel, high accuracy of test results usually requires that the test be completed immediately after staining. Using an automatic sample loader to automate sample loading can reduce the workload of personnel and shorten the sample loading time to a certain extent. However, when the number of samples reaches a certain level, even with an automatic sample loader, the entire detection process can take more than 2 hours. In some detection experiments on metabolites of living cells, the staining time is generally 30 minutes, and 2 hours of cell activity will have a significant impact on the test results. In cell biology, maintaining cells at a low temperature (such as 4°C or on ice) can significantly reduce cell metabolism and prolong the time that cells remain active.

[0004] The existing flow cytometer multi-well plate adapter can adapt to 96-well plates and automatically detect 96 samples at a time, which provides convenience for researchers to conduct high-throughput flow detection experiments. However, most of the adapters used are bottomless hollow aluminum alloy structures, which cannot maintain the low temperature state of cells in the multi-well plate for a long time by pre-freezing or putting in ice cubes. Utility Model Content

[0005] The purpose of the utility model is to provide an adapter for maintaining a porous plate in a low temperature state for a long time to solve the above-mentioned problem, which is adaptable to a variety of porous plates and has a stable installation structure and can quickly cool down and maintain a low temperature for a long time.

[0006] Technical solution: The utility model provides an adapter for maintaining a porous plate in a low temperature state for a long time, comprising: an adapter body, a buckle fixing structure, wherein the adapter body is a solid metal block with a rectangular porous plate mounting groove on the top; the buckle fixing structure comprises: a spring buckle and a fixing screw, wherein the spring buckle is installed on a set of long and short sides of the porous plate mounting groove of the adapter body through the fixing screw. The buckle fixing structure is used to fix the porous plate, thereby improving the stability of the porous plate installation.

[0007] Furthermore, in the above-mentioned adapter for maintaining the multi-hole plate at a low temperature for a long time, the adapter body is made of aluminum alloy, can be placed in a refrigerator or cooled quickly by an ice bath, and is suitable for heat preservation operation.

[0008] Furthermore, in the above-mentioned adapter for maintaining the porous plate in a low temperature state for a long time, a spring sheet groove is provided in the middle of a group of long and short sides of the porous plate mounting slot mounting buckle fixing structure.

[0009] Furthermore, in the above-mentioned adapter for maintaining a porous plate in a low temperature state for a long time, the porous plate mounting groove is 128 mm long, 86 mm wide, and 3 mm deep.

[0010] Furthermore, in the above-mentioned adapter for maintaining the porous plate in a low temperature state for a long time, the length and width of the porous plate installation groove are slightly larger than the length and width of the installed porous plate.

[0011] Furthermore, in the above-mentioned adapter for maintaining the porous plate in a low temperature state for a long time, the buckle fixing structure is arranged in the spring sheet groove, and the spring buckle is made by bending a stainless steel sheet.

[0012] Furthermore, in the above-mentioned adapter for maintaining the multi-hole plate at a low temperature for a long time, an oxide layer is added to the surface of the adapter body, which is wear-resistant and durable, thereby increasing the service life of the adapter.

[0013] Furthermore, the adapter for maintaining the multi-hole plate in a low temperature state for a long time has a main body dimension of 132 mm in length, 90 mm in width and 30 mm in height.

[0014] It can be seen from the above technical scheme that the utility model has the following beneficial effects: the adapter for maintaining the low temperature state of the porous plate for a long time described in the utility model has a simple structure and is easy to operate. A solid metal block is used to open the porous plate installation groove, and it is made of aluminum alloy. A snap-on fixing structure is set to fix the porous plate. It can be placed in a refrigerator or quickly cooled by an ice bath. It is suitable for maintaining a low temperature for a long time and ensuring the stability of the porous plate after installation. An oxide layer is added to the surface, which is wear-resistant and durable, thereby increasing the service life of the adapter. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic diagram of an adapter for maintaining a porous plate at a low temperature for a long time according to the utility model;

[0016] Figure 2 This is a side view of an adapter for maintaining a porous plate at a low temperature for a long time according to the utility model;

[0017] Figure 3 This is a schematic diagram of the buckle fixing structure of the utility model.

[0018] In the figure: adapter body 1, buckle fixing structure 2, perforated plate mounting slot 11, spring sheet slot 12, spring buckle 21, fixing screw 22. DETAILED DESCRIPTION

[0019] Example 1

[0020] like Figure 1-2 The adapter shown in the figure is used to maintain a porous plate in a low temperature state for a long time, comprising: an adapter body 1, a buckle fixing structure 2, wherein the adapter body 1 is a solid metal block with a rectangular porous plate mounting groove 11 on the top; the buckle fixing structure 2 comprises: a spring buckle 21 and a fixing screw 22, wherein the spring buckle 21 is installed on a set of long and short sides of the porous plate mounting groove 11 in the adapter body 1 through the fixing screw 22. By providing the buckle fixing structure 2 to fix the porous plate, the stability of the porous plate installation is improved.

[0021] In this embodiment, the adapter body 1 is made of aluminum alloy, and the porous plate mounting groove 11 is 128 mm long, 86 mm wide, and 3 mm deep. It is made of solid aluminum alloy and can be quickly cooled by placing it in a refrigerator or using an ice bath, which is suitable for heat preservation operation.

[0022] In this embodiment, the adapter body has dimensions of 132 mm in length, 90 mm in width, and 30 mm in height.

[0023] Example 2

[0024] On the basis of Example 1, in this example, Figure 2 The adapter shown is used to maintain the porous plate at a low temperature for a long time, wherein the length and width of the porous plate installation slot 11 are slightly larger than the length and width of the installed porous plate, so as to facilitate the installation and fixing of the porous plate into the adapter.

[0025] In this embodiment, a spring sheet groove 12 is provided in the middle of a group of long and short sides of the perforated plate mounting groove 11 for mounting the buckle fixing structure 2 .

[0026] like Figure 2-3 The adapter shown is used to maintain a porous plate at a low temperature for a long time. The buckle fixing structure 2 is arranged in the spring sheet groove 12, and the spring buckle 21 is made of a stainless steel sheet by bending.

[0027] In this embodiment, an oxide layer is added to the surface of the adapter body 1, which is wear-resistant and durable, thereby increasing the service life of the adapter.

[0028] It should be noted that the above is only a technical solution of the utility model and is not a limitation. Although the utility model is described in detail with reference to the preferred embodiments, a person skilled in the art should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.

Claims

1. An adapter for maintaining a porous plate at a low temperature for a long time, characterized in that: include: An adapter body (1), wherein the adapter body (1) is a solid metal block with a rectangular porous plate mounting groove (11) formed on the top; A buckle fixing structure (2), the buckle fixing structure (2) comprising: a spring buckle (21) and a fixing screw (22), the spring buckle (21) being installed on a set of long and short sides of a porous plate installation groove (11) in an adapter body (1) via the fixing screw (22).

2. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 1, characterized in that: The adapter body (1) is made of aluminum alloy.

3. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 1, characterized in that: A spring sheet groove (12) is provided in the middle of a group of long and short sides of the perforated plate mounting groove (11) for mounting the buckle fixing structure (2).

4. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 1, characterized in that: The porous plate installation groove (11) is 128 mm long, 86 mm wide and 3 mm deep.

5. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 4, characterized in that: The length and width of the porous plate installation groove (11) are slightly greater than the length and width of the installed porous plate.

6. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 1, characterized in that: The buckle fixing structure (2) is arranged in the spring sheet groove (12), and the spring buckle (21) is made by bending a stainless steel sheet.

7. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 1, characterized in that: An oxide layer is added to the surface of the adapter body (1).

8. The adapter for maintaining a porous plate at a low temperature for a long time according to claim 1, characterized in that: The adapter body (1) has dimensions of 132 mm in length, 90 mm in width and 30 mm in height.