Anesthesia injection device for laboratory mice

By designing the piston-adjusted anesthesia gas access area and the uniform plate design of the air extraction mechanism in the mouse anesthesia injection device, the problem of increasing anesthesia gas usage in the small size of mice is solved, and gas saving and operational safety is achieved Sexual effect.

CN222426323UActive Publication Date: 2025-02-07ANHUI MEDICAL UNIV
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Patent Information

Application Number
CN202420540909.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-20
Publication Date
2025-02-07
Estimated Expiration
2034-03-20

AI Technical Summary

Technical Problem

The existing mouse anesthesia injection device is small in the mouse volume and requires excessive anesthesia gas, which leads to an increase in the amount of gas used and is difficult to suck out, affecting operational efficiency and safety.

Method used

An anesthesia injection device for experimental mice was designed. The space volume formed by the inner ring and the front end of the piston was adjusted through the movement of the piston, so that the volume of anesthetic gas could enter the area was smaller, reducing the amount of anesthetic gas used, and at the same time, the gas was extracted. The mechanism and uniform plate are designed to ensure the concentration of anesthetic gas and the inspiration effect.

Benefits of technology

It achieves the reduction of the amount of anesthetic gas, while ensuring the concentration and inspiration effect of anesthetic gas, saving the amount of anesthetic gas, and facilitating the later removal of anesthetic gas, improving operational safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of mouse experiments, and particularly discloses an anesthesia injection device for laboratory mice, which comprises an anesthesia box, the front end of the anesthesia box is fixedly connected with a tail clamping block, the top of the tail clamping block is provided with a tail placing groove, the front end of the anesthesia box is detachably connected with a baffle, and an anesthesia assembly is arranged in the anesthesia box. The anesthesia assembly comprises an inner ring fixedly connected into the anesthesia box, a cavity is formed between the outer wall of the inner ring and the inner wall of the anesthesia box, a piston is slidably connected into the inner ring, an air inlet pipe assembly is arranged at the rear end of the piston, a toothed plate is fixedly connected to the rear end of the piston, and the rear end of the toothed plate penetrates through the anesthesia box and is slidably connected with the anesthesia box. Through the cooperation of the structures, the size of the area where gas for anesthetizing mice can be introduced is small, and the concentration of the anesthetic gas in the space can be guaranteed while the use amount of the anesthetic gas is reduced.
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Description

Technical Field

[0001] The utility model relates to the technical field of mouse experiments, in particular to an anesthesia injection device for experimental mice. Background Art

[0002] Laboratories often conduct animal experiments and research. When using experimental mice to verify the performance of tracers, the effects of drugs, or obtain treatment data, tail vein injection is often used to introduce them into the experimental mice. Since mice are small and will instinctively resist and struggle when receiving treatment in a painful state, tail vein injection of mice is very difficult.

[0003] In order to avoid pain in mice during drug injection, it is usually necessary to anesthetize the experimental mice first and then perform tail vein injection on them.

[0004] For example, the "A device for anesthesia and tail vein injection for mice and rats" with the authorization announcement number "CN215080184U" mainly sets an anesthesia box behind the mouse tail fixing part to fix the mouse tail after gas anesthesia induction. It is easy to operate and has high efficiency in mouse tail injection.

[0005] In actual use, since the sizes of mice are different, but in the above scheme, the length of the anesthesia box is fixed. When the size of the mouse is small, more anesthetic gas still needs to be injected into the anesthesia box, which leads to an increase in the use of anesthetic gas. Excessive use of anesthetic gas can easily make it difficult to suck out the anesthetic gas inside the anesthesia box. Summary of the invention

[0006] The purpose of the utility model is to provide an anesthesia injection device for experimental mice, which can reduce the volume of the area where gas used to anesthetize mice can pass, and can reduce the amount of anesthetic gas used while ensuring the concentration of anesthetic gas in the space, so as to solve the problems raised in the above-mentioned background technology.

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an anesthesia injection device for experimental mice, comprising an anesthesia box, a tail clamp block is fixedly connected to the front end of the anesthesia box, a tail groove is provided on the top of the tail clamp block, a baffle is detachably connected to the front end of the anesthesia box, an anesthesia assembly is arranged inside the anesthesia box, the anesthesia assembly comprises an inner ring fixedly connected to the inside of the anesthesia box, a cavity is arranged between the outer wall of the inner ring and the inner wall of the anesthesia box, a piston is slidably connected to the inside of the inner ring, and an air intake pipe assembly is arranged at the rear end of the piston.

[0008] Preferably, the rear end of the piston is fixedly connected to a tooth plate, the air intake pipe assembly is located on the left side of the tooth plate, the rear end of the tooth plate passes through the anesthesia box and is slidably connected to the anesthesia box, and a tooth groove is provided on the right side of the tooth plate.

[0009] Preferably, a connecting plate is fixedly connected to the rear end of the anesthesia box, a motor is fixedly connected to the top of the connecting plate, a gear is fixedly connected to the output end of the motor, and the tooth grooves formed on the gear plate mesh with the gear.

[0010] Preferably, a sealing gasket is fixedly connected to the rear end of the baffle.

[0011] Preferably, an exhaust mechanism is provided inside the anesthesia box, and the exhaust mechanism includes an absorption ring slidably connected between the anesthesia box and the inner ring, and suction pipes are provided at the rear ends of both sides of the right side of the absorption ring, and a plurality of ventilation holes are opened inside the inner ring.

[0012] Preferably, an empty groove is provided inside the absorption ring, a uniform plate is fixedly connected inside the empty groove, a plurality of suction holes are provided at the front ends of the uniform plate and the absorption ring, and the suction holes on the uniform plate and the suction holes on the absorption ring are staggered.

[0013] Preferably, the air intake pipe assembly comprises a small tube fixedly plugged into the rear end of the piston, a sleeve is slidably connected to the rear end outer wall of the small tube, and an O-ring is fixedly installed on the front end inner wall of the sleeve.

[0014] Preferably, a tee is fixedly mounted on the middle portion of the sleeve, and valves are mounted on the top and right side of the tee.

[0015] Compared with the prior art, the beneficial effects of the utility model are:

[0016] 1. The volume of the space formed by the front end of the piston and the inner ring is adjusted by the movement of the piston, so that the volume of the area where the gas used to anesthetize the mice can pass is smaller, which can reduce the amount of anesthetic gas used while ensuring the concentration of anesthetic gas in the space, thereby saving the amount of anesthetic gas used. At the same time, the reduction in the amount of anesthetic gas used also facilitates the removal of anesthetic gas inside the anesthesia box at a later stage;

[0017] 2. The design of staggered arrangement of the suction holes on the uniform plate and the suction holes on the absorption ring makes the absorption ring more uniform when sucking air into the cavity, so that the effect of absorbing anesthetic gas is better. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the specific implementation methods of the utility model or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0019] Figure 1 This is the overall structural view of the utility model;

[0020] Figure 2 It is a schematic diagram of a half-section structure of the utility model;

[0021] Figure 3 It is a schematic diagram of the top-section structure of the anesthesia box of the utility model;

[0022] Figure 4 It is a partial half-section structural schematic diagram of the casing of the utility model;

[0023] Figure 5 It is a schematic diagram of the overall rear view structure of the utility model.

[0024] Description of reference numerals:

[0025] 1. Anesthesia box; 2. Tail block; 3. Tail groove; 4. Baffle; 5. Anesthesia assembly; 51. Inner ring; 52. Cavity; 53. Piston; 54. Inlet pipe assembly; 541. Small tube; 542. Sleeve; 543. O-ring; 544. Tee; 545. Valve; 55. Tooth plate; 56. Tooth groove; 57. Connecting plate; 58. Motor; 59. Gear; 6. Vacuum mechanism; 61. Absorption ring; 62. Suction pipe; 63. Vent; 64. Slot; 65. Uniform plate; 66. Suction hole; 7. Sealing pad. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] See also Figures 1 to 5The utility model provides a technical solution: an anesthesia injection device for experimental mice, comprising an anesthesia box 1, a tail clamp block 2 is fixedly connected to the front end of the anesthesia box 1, a tail slot 3 is arranged on the top of the tail clamp block 2, a baffle 4 is detachably connected to the front end of the anesthesia box 1, an anesthesia component 5 is arranged inside the anesthesia box 1, and the anesthesia component 5 includes an inner ring 51 fixedly connected to the inside of the anesthesia box 1, a cavity 52 is arranged between the outer wall of the inner ring 51 and the inner wall of the anesthesia box 1, a piston 53 is slidably connected to the inside of the inner ring 51, and the rear end of the piston 53 An air intake pipe assembly 54 is provided, and a tooth plate 55 is fixedly connected to the rear end of the piston 53. The air intake pipe assembly 54 is located on the left side of the tooth plate 55. The rear end of the tooth plate 55 penetrates the anesthesia box 1 and is slidably connected to the anesthesia box 1. A tooth groove 56 is provided on the right side of the tooth plate 55. A connecting plate 57 is fixedly connected to the rear end of the anesthesia box 1. A motor 58 is fixedly connected to the top of the connecting plate 57. A gear 59 is fixedly connected to the output end of the motor 58. The tooth groove 56 provided on the tooth plate 55 is meshed with the gear 59. A sealing gasket 7 is fixedly connected to the rear end of the baffle 4.

[0028] By adopting the above technical solution, the detachable connection between the baffle plate 4 and the front end of the anesthesia box 1 can be bolted or magnetically connected. When in use, the mouse is placed in the anesthesia box 1, and the tail of the mouse is close to the end of the tail clamp 2, and the tail of the mouse is placed at this time. The position of the piston 53 is adjusted according to the body length of the mouse. During adjustment, the output shaft of the motor 58 rotates, so that the gear 59 rotates accordingly, and the tooth groove 56 provided in the tooth plate 55 is engaged with the gear 59, so that the tooth plate 55 can move, thereby controlling the movement of the piston 53, and moving the piston 53 to a position close to the mouse head. At this time, the baffle plate 4 is covered at the front end of the anesthesia box 1, and the air for anesthetizing the mouse is passed into the anesthesia box 1 through the air inlet pipe assembly 54. The gas used to anesthetize the mouse enters the inner ring 51 and is at the front end of the piston 53. In this way, the volume of the space formed by the front end of the piston 53 and the inner ring 51 can be adjusted by the movement of the piston 53, so that the volume of the area where the gas used to anesthetize the mouse can pass is smaller, which can reduce the use of anesthetic gas while ensuring the concentration of anesthetic gas in the space, thereby achieving the purpose of saving the use of anesthetic gas. At the same time, the reduction in the use of anesthetic gas also facilitates the later removal of anesthetic gas inside the anesthesia box 1. After anesthesia, the mouse's tail can be injected with drugs. A small plate is fixedly connected to the bottom of the front end of the tooth plate 55, and a magnetic ring is fixedly connected to the bottom of the small plate. The absorption ring 61 is made of iron. When the piston 53 moves, the absorption ring 61 moves synchronously under the action of the magnetic force.

[0029] Specifically, Figures 1 to 3As shown, an exhaust mechanism 6 is provided inside the anesthesia box 1, and the exhaust mechanism 6 includes an absorption ring 61 slidably connected between the anesthesia box 1 and the inner ring 51, and suction pipes 62 are provided on both sides of the right rear end of the absorption ring 61. A plurality of vents 63 are provided inside the inner ring 51, and an empty groove 64 is provided inside the absorption ring 61. A uniform plate 65 is fixedly connected inside the empty groove 64. A plurality of suction holes 66 are provided at the front ends of the uniform plate 65 and the absorption ring 61. The suction holes 66 on the uniform plate 65 and the suction holes 66 on the absorption ring 61 are staggered. The air inlet pipe assembly 54 includes a small tube 541 fixedly inserted at the rear end of the piston 53, and a sleeve 542 is slidably connected to the rear end outer wall of the small tube 541, and an O-ring 543 is fixedly installed on the front end inner wall of the sleeve 542. A tee 544 is fixedly installed on the middle part of the sleeve 542, and valves 545 are installed on the top and right side of the tee 544.

[0030] By adopting the above technical solution, when injecting medicine, the valve 545 on the top of the three-way 544 is closed, and the valve 545 on the right side of the three-way 544 is opened. After the mouse is injected with medicine, the anesthetic gas inside the anesthesia box 1 is sucked out by connecting the suction pipe 62 to the external hose, and the hose is connected to the external suction equipment, so as to avoid the leakage of anesthetic gas to affect the health of the staff. By closing the valve 545 on the right side of the three-way 544 and opening the valve 545 on the top of the three-way 544, during the inhalation process, the external air can enter the interior of the sleeve 542 from the top of the three-way 544, and then enter the front end area of ​​the piston 53 from the small tube 541, ensuring that the front end area of ​​the piston 53 will not cause negative pressure due to inhalation. During inhalation, the anesthetic gas at the front end of the piston 53 in the inner ring 51 enters the cavity 52 through the vent hole 63, and then the anesthetic gas enters the absorption ring 61 and enters the external inhalation device from the inhalation pipe 62. The inhalation holes 66 on the uniform plate 65 and the inhalation holes 66 on the absorption ring 61 are staggered, so that the absorption ring 61 inhales the cavity 52 more evenly, so that the effect of absorbing the anesthetic gas is better. The design of the O-ring 543 does not affect the sliding between the sleeve 542 and the small tube 541, and ensures the sealing effect between the sleeve 542 and the small tube 541. When the anesthetic gas enters, the absorption ring 61 blocks the cavity 52 to prevent the anesthetic gas from entering the rear end of the absorption ring 61.

[0031] Working principle: Place the mouse in the anesthesia box 1, and the tail of the mouse is at one end close to the tail clamp 2, and the tail of the mouse is placed at this time to adjust the position of the piston 53 according to the body length of the mouse. During adjustment, the output shaft of the motor 58 rotates, so that the gear 59 rotates accordingly, so that the tooth plate 55 moves, thereby controlling the movement of the piston 53. In this way, the volume of the space formed by the front end of the piston 53 and the inside of the inner ring 51 can be adjusted by the movement of the piston 53, so that the volume of the area where the gas used to anesthetize the mouse can pass is smaller, while reducing the use of anesthetic gas. The concentration of anesthetic gas in the space is guaranteed, and the anesthetic gas inside the anesthesia box 1 is sucked out to avoid the leakage of anesthetic gas. The health of the staff is affected. When inhaling through the suction pipe 62, the anesthetic gas at the front end of the piston 53 inside the inner ring 51 enters the interior of the cavity 52 through the vent 63, and then the gas used for anesthesia enters the absorption ring 61 and enters the external suction device from the suction pipe 62.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solution deviate from the scope of the technical solution of the embodiments of the utility model.

Claims

1. An anesthesia injection device for experimental mice, comprising an anesthesia box (1), characterized in that: The front end of the anesthesia box (1) is fixedly connected to a tail clamp block (2), the top of the tail clamp block (2) is provided with a tail slot (3), and the front end of the anesthesia box (1) is detachably connected to a baffle plate (4); An anesthesia assembly (5) is arranged inside the anesthesia box (1), and the anesthesia assembly (5) comprises an inner ring (51) fixedly connected inside the anesthesia box (1), a cavity (52) is arranged between the outer wall of the inner ring (51) and the inner wall of the anesthesia box (1), a piston (53) is slidably connected inside the inner ring (51), and an air intake pipe assembly (54) is arranged at the rear end of the piston (53).

2. The anesthesia injection device for experimental mice according to claim 1, characterized in that: The rear end of the piston (53) is fixedly connected to a tooth plate (55), the air inlet pipe assembly (54) is located on the left side of the tooth plate (55), the rear end of the tooth plate (55) penetrates the anesthesia box (1) and is slidably connected to the anesthesia box (1), and a tooth groove (56) is provided on the right side of the tooth plate (55).

3. The anesthesia injection device for experimental mice according to claim 2, characterized in that: A connecting plate (57) is fixedly connected to the rear end of the anesthesia box (1), a motor (58) is fixedly connected to the top of the connecting plate (57), a gear (59) is fixedly connected to the output end of the motor (58), and a tooth groove (56) provided on the tooth plate (55) is meshed with the gear (59).

4. The anesthesia injection device for experimental mice according to claim 3, characterized in that: A sealing gasket (7) is fixedly connected to the rear end of the baffle (4).

5. The anesthesia injection device for experimental mice according to claim 4, characterized in that: An air extraction mechanism (6) is arranged inside the anesthesia box (1), and the air extraction mechanism (6) comprises an absorption ring (61) slidably connected between the anesthesia box (1) and the inner ring (51), and suction pipes (62) are arranged at the rear ends of both sides of the right side of the absorption ring (61), and a plurality of ventilation holes (63) are opened inside the inner ring (51).

6. The anesthesia injection device for experimental mice according to claim 5, characterized in that: The absorption ring (61) is provided with an empty groove (64) inside, and a uniform plate (65) is fixedly connected inside the empty groove (64). The uniform plate (65) and the front end of the absorption ring (61) are provided with a plurality of suction holes (66), and the suction holes (66) on the uniform plate (65) and the suction holes (66) on the absorption ring (61) are arranged in an alternating manner.

7. The anesthesia injection device for experimental mice according to claim 6, characterized in that: The air intake pipe assembly (54) comprises a small tube (541) fixedly plugged into the rear end of the piston (53); a sleeve (542) is slidably connected to the rear end outer wall of the small tube (541); and an O-type sealing ring (543) is fixedly installed on the front end inner wall of the sleeve (542).

8. The anesthesia injection device for experimental mice according to claim 7, characterized in that: A tee (544) is fixedly mounted in the middle portion of the sleeve (542), and valves (545) are mounted on the top and right side of the tee (544).

Citation Information

Patent Citations

  • Rat and mouse anesthesia and caudal vein injection device

    CN215080184U