Fixing device for intravenous injection of mouse caudal vein

Abstract

The utility model discloses a mouse caudal vein injection fixing device which comprises a fixed base, a movable base is arranged on the upper end face of the fixed base, a first positioning hinge is arranged between the rear end of the movable base and the rear end of the fixed base, and a caudal vein injection platform is arranged at the front end of the movable base. A second positioning hinge is arranged between the rear end of the caudal vein injection platform and the front end of the movable base, a supporting rod is arranged at the bottom of the caudal vein injection platform, one end of the supporting rod is hinged to the bottom of the caudal vein injection platform, and the other end of the supporting rod is hinged to the fixed base; the fixed base, the movable base, the caudal vein injection platform and the supporting rod form a double-rocker mechanism; an elastic bandage is fixedly arranged on one side face of the movable base, and a bandage positioning strip is fixedly arranged on the other side face of the movable base. According to the technical scheme, the mouse fixing device is reasonable in structural design, convenient to use, reliable in mouse fixing, small in mouse damage during fixing, convenient to clean and good in practicability.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental equipment, in particular to a fixing device for mouse tail vein injection. Background Art

[0002] Mouse tail vein injection fixture is widely used in laboratories of various scientific and biological research centers, animal quarantine centers and colleges and universities.

[0003] Mouse tail vein injection is often used for drug screening and acute toxicity tests. Traditional mouse tail vein injection fixtures are mostly cylindrical with an opening at one end that can be closed and the other end that can be breathable. The main principle of use is to stuff the mouse into the cylinder during injection, close one end of the cylinder, and expose the mouse's tail through the opening at the end for tail vein injection. Although the above-mentioned fixture device can achieve the expected purpose in actual use, there are still some problems that need to be improved: 1. The traditional mouse tail vein injection fixture fixes the mouse by squeezing, which has great damage to its spinal health and can cause death in severe cases. 2. In a narrow space such as a cylinder, the mouse will tend to turn its head back, that is, fold its head to the abdomen, which will cause its spinal fracture and death. 3. It is difficult for the traditional mouse tail vein injection fixture to allow the mouse to enter. If brute force is used to drag it, it is easy to cause the mouse to be injured or produce a stress response, which will cause certain harm to the experimental mouse. 4. The traditional mouse tail vein injection fixture does not have the function of adjusting the height when in use. During long-term experiments, taller or shorter experimenters are prone to waist discomfort. 5. The interior of the traditional mouse tail vein injection fixture is difficult to clean and easily has stains. 6. The traditional mouse tail vein injection fixture cannot be adjusted and fixed according to the size of the mouse. 7. The traditional mouse tail vein injection fixture lacks light assistance, and sometimes it may be difficult to find the mouse tail vein, resulting in poor practicality. Utility Model Content

[0004] In view of the shortcomings of the prior art, the purpose of the utility model is to provide a fixation device for mouse tail vein injection which has a reasonable structural design, is easy to use, can reliably fix mice, causes little damage to mice during fixation, is easy to clean and has good practicality.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a fixing device for mouse tail vein injection, comprising a fixed base, a movable base is arranged on the upper end surface of the fixed base, a first positioning hinge is arranged between the rear end of the movable base and the rear end of the fixed base, a tail vein injection platform is arranged at the front end of the movable base, a second positioning hinge is arranged between the rear end of the tail vein injection platform and the front end of the movable base, and a support rod is arranged at the bottom of the tail vein injection platform, one end of the support rod is hinged to the bottom of the tail vein injection platform, and the other end of the support rod is hinged to the fixed base; the fixed base, the movable base, the tail vein injection platform and the support rod together constitute a double rocker mechanism;

[0006] A mouse body positioning groove is fixedly arranged on the upper end surface of the movable base, a plurality of steel bars are fixedly arranged in the mouse body positioning groove, an elastic bandage is fixedly arranged on one side surface of the movable base, and a bandage positioning strip is fixedly arranged on the other side surface of the movable base;

[0007] The movable base is fixedly provided with a rat tail fixing plate near the tail vein injection platform end, and a first rat tail positioning groove with an opening facing upward is provided in the middle of the rat tail fixing plate;

[0008] A positioning strip is fixedly arranged on the upper end surface of the tail vein injection platform in alignment with the first rat tail positioning groove, and a second rat tail positioning groove is arranged on the upper end surface of the positioning strip, and the second rat tail positioning groove is arranged in alignment with the first rat tail positioning groove.

[0009] The utility model is further configured as follows: the vertical distance between the first positioning hinge and the second positioning hinge is 16-17 cm, the vertical distance between the second positioning hinge and the hinge between the tail vein injection platform and the support rod is 3-4 cm, the vertical distance between the hinge between the tail vein injection platform and the support rod and the hinge between the support rod and the fixed base is 9-10 cm, and the vertical distance between the hinge between the support rod and the fixed base and the first positioning hinge is 10-11 cm.

[0010] The utility model is further configured as follows: the first positioning hinge is a square plate flat hinge with a torque adjustment function, and the second positioning hinge is a butterfly flat hinge.

[0011] The utility model is further configured as follows: the tail vein injection platform is provided with an illumination lamp at one side or both sides of the second mouse tail positioning groove.

[0012] The utility model is further configured as follows: a support rod placement groove is arranged on the upper end surface of the fixed base in alignment with the position of each support rod.

[0013] The utility model is further configured as follows: two support rods are provided in total, and the two support rods are symmetrically arranged.

[0014] The beneficial effects of the utility model are as follows: compared with the prior art, the utility model has a reasonable structural design. Before using the fixing device for mouse tail vein injection of the utility model, the user first adjusts the fixing device for mouse tail vein injection to a suitable height, uses an inner hexagonal wrench to tighten the first positioning hinge to fix the movable base, places the target mouse in the mouse body positioning groove of the movable base, and after the mouse grabs the steel bar, fully stretches the mouse body part and inserts the root of the mouse tail into the first mouse tail positioning groove and the second mouse tail positioning groove. At this time, the mouse body should be in an elongated state, and at the same time, the elastic bandage is passed over the mouse and adhered to the bandage positioning strip to fix the mouse body. The user then turns on the lighting lamp to ensure that the tail vein is clearly visible under the lamp, and then performs the tail vein injection operation in the second mouse tail positioning groove on the tail vein injection platform; after the operation is completed, the inner hexagonal wrench is used to loosen the first positioning hinge, and the movable base is put down to clean the device. It is easy to use and can complete the tail vein injection operation in a short time; the mouse is reliably fixed and has a protective effect on the inherent morphology of the mouse, which can avoid damage to the health of the experimental mice; the mouse is less damaged during fixation, and the tightness of the fixation can be adjusted arbitrarily according to the size of the mouse; the fixing device is integrated and portable, and is a good helper for scientific researchers; the open structure is easy to clean; the liftable platform is convenient for the operator to operate at different height platforms, and it is practical.

[0015] The utility model is further described below in conjunction with the accompanying drawings and specific embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 The structure of the embodiment of the utility model in the unfolded state is shown in FIG. Figure 1 ;

[0017] Figure 2 The structure of the embodiment of the utility model in the unfolded state is shown in FIG. Figure 2 ;

[0018] Figure 3 It is an exploded schematic diagram of an embodiment of the utility model;

[0019] Figure 4 It is a schematic diagram of the structure of the embodiment of the utility model in a folded state. DETAILED DESCRIPTION

[0020] In the description of this embodiment, it should be noted that if the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", "front", "back", etc. appear, the orientation or position relationship indicated is based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore, cannot be understood as a limitation on the utility model. In addition, if the terms "first", "second", and "third" appear, they are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0021] See also Figures 1 to 4 The utility model discloses a fixing device for mouse tail vein injection, comprising a fixed base, a movable base 2 is arranged on the upper end surface of the fixed base 1, a first positioning hinge 10 is arranged between the rear end of the movable base 2 and the rear end of the fixed base 1, a tail vein injection platform 3 is arranged at the front end of the movable base 2, a second positioning hinge 20 is arranged between the rear end of the tail vein injection platform 3 and the front end of the movable base 2, and a support rod 4 is arranged at the bottom of the tail vein injection platform 3, one end of the support rod 4 is hinged to the bottom of the tail vein injection platform 3, and the other end of the support rod 4 is hinged to the fixed base 1; the fixed base 1, the movable base 2, the tail vein injection platform 3 and the support rod 4 together constitute a double rocker mechanism;

[0022] A mouse body positioning groove 21 is fixedly provided on the upper end surface of the movable base 2, and a plurality of steel bars 5 are fixedly provided in the mouse body positioning groove 21. An elastic bandage 6 is fixedly provided on one side surface of the movable base 2, and a bandage positioning strip 7 is fixedly provided on the other side surface of the movable base 2.

[0023] The movable base 2 is fixedly provided with a rat tail fixing plate 8 near the tail vein injection platform end, and a first rat tail positioning groove 81 with an opening facing upward is provided in the middle of the rat tail fixing plate 8;

[0024] A positioning bar 31 is fixedly arranged on the upper end surface of the tail vein injection platform 3 in alignment with the first rat tail positioning groove 81 , and a second rat tail positioning groove 311 is arranged on the upper end surface of the positioning bar 31 , and the second rat tail positioning groove 311 is arranged in alignment with the first rat tail positioning groove 81 .

[0025] Preferably, the number of steel bars 5 in the mouse body positioning groove 21 is set to be more than 10, and the number of steel bars 5 in this embodiment is set to be 18 in total, with a spacing of 0.8 cm between the steel bars 5, and the two ends of each steel bar 5 are respectively fixedly connected to the left and right inner wall surfaces of the mouse body positioning groove. The elastic bandage 6 is a magic elastic bandage, and the bandage positioning strip 7 is a Velcro strip that matches the magic elastic bandage. The elastic bandage 6 is fixed to the left side of the movable base 2 by glue bonding or by screw locking, and the bandage positioning strip 7 is fixed to the right side of the movable base 2 by glue bonding or by screw connection; the positioning strip 31 is integrally set with the upper end surface of the tail vein injection platform 3 or fixed by glue bonding.

[0026] In order to make the structural design of the utility model more reasonable, as a preferred embodiment, the vertical distance between the first positioning hinge 10 and the second positioning hinge 20 in this embodiment is 16-17 cm, the vertical distance between the second positioning hinge 20 and the hinge between the tail vein injection platform 3 and the support rod 4 is 3-4 cm, the vertical distance between the hinge between the tail vein injection platform 3 and the support rod 4 and the hinge between the support rod 4 and the fixed base 1 is 9-10 cm, and the vertical distance between the hinge between the support rod 4 and the fixed base 1 and the first positioning hinge 10 is 10-11 cm.

[0027] The first positioning hinge 10 is a square plate flat hinge with a torque adjustment function, and the second positioning hinge 20 is a butterfly flat hinge. The position of the movable base 2 can be fixed by tightening the first positioning hinge 10 with a hexagonal wrench.

[0028] The tail vein injection platform 3 is provided with an illumination lamp 9 on one side or on both sides of the second mouse tail positioning groove 311. Preferably, the illumination lamp 9 is fixed to the tail vein injection platform 3 by glue or screw connection, a dry cell is provided in the illumination lamp 9, and a control switch is provided on the illumination lamp 9.

[0029] The upper end surface of the fixed base 1 is provided with a support rod placement groove 11 aligned with the position of each support rod 4. Preferably, the support rods 4 described in this embodiment are provided with two in total, and the two support rods 4 are symmetrically arranged, each support rod 4 is hinged to the bottom of the tail vein injection platform 3 through a pin or a hinge, and each support rod 4 is hinged to the upper end surface of the fixed base 1 through a pin or a hinge.

[0030] In actual application, before using the fixing device for mouse tail vein injection of the utility model, the user first adjusts the fixing device for mouse tail vein injection to an appropriate height, uses an Allen wrench to tighten the first positioning hinge to fix the movable base, places the target mouse in the mouse body positioning groove of the movable base, and after the mouse grabs the steel bar, fully stretches the mouse body part and inserts the root of the mouse tail into the first mouse tail positioning groove and the second mouse tail positioning groove. At this time, the mouse body should be in an elongated state, and at the same time, the elastic bandage is passed over the top of the mouse and adhered to the bandage positioning strip to fix the mouse body. The user then turns on the lighting lamp, ensures that the tail vein is clearly visible under the lamp, and then performs the tail vein injection operation in the second mouse tail positioning groove on the tail vein injection platform; after the operation is completed, the first positioning hinge is loosened with an Allen wrench, the movable base is lowered, and the device is cleaned.

[0031] The utility model has the following beneficial effects:

[0032] (1) Ensure the stability and straightness of the mouse body, and avoid spinal compression that may be caused by traditional mouse fixation devices;

[0033] (2) The mice can be easily placed in the laboratory without the need to drag them with brute force, thus avoiding unnecessary damage to the experimental mice;

[0034] (3) It is a mouse-friendly fixation device that uses the mouse's grasping characteristics for fixation;

[0035] (4) It can be fixed quickly, making it convenient for the operator to operate;

[0036] (5) The fixation can be adjusted according to the size of the mouse, making the mouse more firmly fixed;

[0037] (6) The lighting can effectively help the operator see the tail vein and speed up the operation process;

[0038] (7) Compared with the traditional cylindrical fixing device, the marks left by the fixing device for mouse tail vein injection in the utility model can be directly removed with a brush, which is convenient to remove;

[0039] (8) The fixing device is integrated and easy to operate;

[0040] (9) The operating table can be raised or lowered to facilitate operations by different operators at different heights.

[0041] In summary, the utility model has a reasonable structural design, is easy to use, and can complete the tail vein injection operation in a relatively short time; the mouse can be reliably fixed, has a protective effect on the inherent morphology of the mouse, and can avoid damage to the health of the experimental mice; the mouse is less damaged during fixation, and the tightness of the fixation can be adjusted arbitrarily according to the size of the mouse; the fixing device is integrated and portable, and is a good helper for scientific researchers; the open structure is easy to clean; the liftable platform is convenient for the operator to operate at different height platforms, and has good practicality.

[0042] The specific description of the present invention in the above embodiments is only used to further illustrate the present invention and cannot be understood as limiting the scope of protection of the present invention. Technical engineers in this field may make some non-essential improvements and adjustments to the present invention based on the contents of the above-mentioned utility model, which fall within the scope of protection of the present invention.

Claims

1. A fixing device for mouse tail vein injection, comprising a fixing base, characterized in that: A movable base (2) is arranged on the upper end surface of the fixed base (1), a first positioning hinge (10) is arranged between the rear end of the movable base (2) and the rear end of the fixed base (1), a tail vein injection platform (3) is arranged at the front end of the movable base (2), a second positioning hinge (20) is arranged between the rear end of the tail vein injection platform (3) and the front end of the movable base (2), and a support rod (4) is arranged at the bottom of the tail vein injection platform (3), one end of the support rod (4) is hinged to the bottom of the tail vein injection platform (3), and the other end of the support rod (4) is hinged to the fixed base (1); the fixed base (1), the movable base (2), the tail vein injection platform (3) and the support rod (4) together constitute a double rocker mechanism; A mouse body positioning groove (21) is fixedly provided on the upper end surface of the movable base (2), a plurality of steel bars (5) are fixedly provided in the mouse body positioning groove (21), an elastic bandage (6) is fixedly provided on one side surface of the movable base (2), and a bandage positioning strip (7) is fixedly provided on the other side surface of the movable base (2); A rat tail fixing plate (8) is fixedly arranged on the movable base (2) near the tail vein injection platform end, and a first rat tail positioning groove (81) with an opening facing upward is arranged in the middle of the rat tail fixing plate (8); A positioning strip (31) is fixedly arranged on the upper end surface of the tail vein injection platform (3) in alignment with the first rat tail positioning groove (81), and a second rat tail positioning groove (311) is arranged on the upper end surface of the positioning strip (31), and the second rat tail positioning groove (311) is arranged in alignment with the first rat tail positioning groove (81).

2. A fixation device for mouse tail vein injection according to claim 1, characterized in that: The vertical distance between the first positioning hinge (10) and the second positioning hinge (20) is 16-17 cm, the vertical distance between the second positioning hinge (20) and the hinge between the tail vein injection platform (3) and the support rod (4) is 3-4 cm, the vertical distance between the hinge between the tail vein injection platform (3) and the support rod (4) and the hinge between the support rod (4) and the fixed base (1) is 9-10 cm, and the vertical distance between the hinge between the support rod (4) and the fixed base (1) and the first positioning hinge (10) is 10-11 cm.

3. A fixation device for mouse tail vein injection according to claim 2, characterized in that: The first positioning hinge (10) is a square plate flat hinge with a torque adjustment function, and the second positioning hinge (20) is a butterfly flat hinge.

4. A fixation device for mouse tail vein injection according to claim 3, characterized in that: The tail vein injection platform (3) is provided with an illumination lamp (9) at one side or at both left and right sides of the second mouse tail positioning groove (311).

5. A fixation device for mouse tail vein injection according to claim 4, characterized in that: The upper end surface of the fixed base (1) is provided with a support rod placement groove (11) aligned with the position of each support rod (4).

6. A fixation device for mouse tail vein injection according to claim 1 or 5, characterized in that: A total of two support rods (4) are provided, and the two support rods (4) are symmetrically arranged.

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