Polypeptide synthesis filtering type reaction kettle with protective structure

Abstract

The utility model relates to the technical field of reaction kettles, in particular to a polypeptide synthesis filtering type reaction kettle with a protection structure. The reaction kettle comprises a fixing frame, the inner surface of the fixing frame is fixedly connected with a reaction kettle body, the surface of the reaction kettle body is provided with a discharging port, the surface of the fixing frame is provided with an operation panel, the surface of the discharging port is provided with a protection device, the protection device comprises a support, the support is fixedly connected with the surface of the discharging port, and the operation panel is arranged on the surface of the support. A round rod is fixedly connected to the inner surface of the support, a connecting plate is rotatably connected to the arc surface of the round rod, a protective cover is fixedly connected to one side of the connecting plate, an L-shaped plate is fixedly connected to the surface of the discharging port, a screw is inserted into the L-shaped plate in a threaded mode, and a limiting block is rotatably connected to one end of the screw. The problems that dust or impurities in external air are attached to an inner cavity of the discharging port and are prone to pollution, and the purity and quality of products are reduced are solved.

Description

Technical Field

[0001] The utility model relates to the technical field of reaction kettles, in particular to a filtering reaction kettle for polypeptide synthesis with a protective structure. Background Art

[0002] Polypeptide is a biologically active substance related to various cell functions in organisms. Its molecular structure is between amino acids and proteins. It is a compound composed of multiple amino acids connected by peptide bonds in a certain order. It needs to be processed and synthesized in a reactor. Reactors are widely used in petroleum, chemical, rubber, pesticide, dye, medicine, food and other industries. They are mainly used to complete chemical process such as vulcanization, nitration, hydrogenation, polymerization, condensation and other reaction equipment.

[0003] A Chinese patent application CN201921285193.4 discloses a filtering reaction vessel for peptide synthesis, and the key points of its technical solution are: 1. Complete functions; the reactor has both reactor functions and filtering functions, and can realize repeated operations of reaction, washing and filtering, without the need to configure filters and other auxiliary equipment separately; 2. High degree of automation; compared with the prior art, the reactor can control the discharge through a pneumatic expansion valve, and combined with a TCU temperature control system and a nitrogen seal and tail gas system, it can also automatically control key parameters such as temperature and pressure, which is easy to operate and highly intelligent; 3. Safe, environmentally friendly and reliable; the reactor is made of metal or enamel material, and is equipped with a pressure regulating valve, which can automatically control the pressure in the reactor, which is safe and reliable; all reaction processes are completed in closed equipment and pipelines, and operators do not need to contact materials, and the production process is safer and more environmentally friendly; in summary, the polypeptide reaction vessel of the present scheme has both reactor functions and filtering functions, and its functions are relatively complete, with a high degree of automation and easy operation. In addition, its production process is safer and more environmentally friendly.

[0004] In view of the above and existing related technologies, the inventors believe that the following defects often exist: dust or impurities in the outside air adhere to the inner cavity of the discharge port, which is easily contaminated, resulting in a decrease in the purity and quality of the product; therefore, in view of the above problems, a filtering reactor for polypeptide synthesis with a protective structure is proposed. Utility Model Content

[0005] The utility model aims to solve the disadvantage in the prior art that dust or impurities in the external air adhere to the inner cavity of the discharge port, resulting in a decrease in the purity and quality of the product, and proposes a filtering reactor for polypeptide synthesis with a protective structure.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a filtering reactor for polypeptide synthesis with a protective structure, comprising a fixed frame, the inner surface of the fixed frame is fixedly connected to a reactor body, the surface of the reactor body is equipped with a discharge port, the surface of the fixed frame is equipped with an operation panel, the surface of the discharge port is provided with a protective device, the protective device comprises a bracket, the bracket is fixedly connected to the surface of the discharge port, the inner surface of the bracket is fixedly connected to a round rod, the circular arc surface of the round rod is rotatably connected to a connecting plate, one side of the connecting plate is fixedly connected to a protective cover, the surface of the discharge port is fixedly connected to an L-shaped plate, a screw is inserted into the internal thread of the L-shaped plate, and one end of the screw is rotatably connected to a limiting block.

[0007] The effect achieved by the above components is: by setting up the protective device, the discharge port is protected, avoiding dust or impurities in the outside air from adhering to the inner cavity of the discharge port, which is easily contaminated and causes the purity and quality of the product to decrease, thereby improving the practicability of the device.

[0008] Preferably, a sliding rod is slidably inserted in the L-shaped plate, and one end of the sliding rod is fixedly connected to the limiting block.

[0009] The effects achieved by the above components are: preventing the limit block from rotating with the rotation of the screw rod, thereby improving the stability of the device.

[0010] Preferably, the arc surface of the round rod is sleeved with two torsion springs, and two ends of the torsion springs are fixedly connected to the bracket and the connecting plate respectively.

[0011] The effects achieved by the above components are: the torsion of the torsion spring drives the connecting plate to rotate on the arc surface of the round rod, and the connecting plate drives the protective cover to rotate automatically and maintain the position state, thereby improving the convenience of the device.

[0012] Preferably, one end of the screw rod away from the limiting block is fixedly connected to a handle, and a surface of the handle has a plurality of protrusions.

[0013] The effect achieved by the above components is: to facilitate work, the screw rod can be quickly and accurately rotated to control the position of the limit block.

[0014] Preferably, adjustment devices are provided on both sides of the operation panel, and the adjustment devices include two slides, and the two slides are fixedly connected to the two sides of the operation panel, and long rods are slidably inserted in the two slides, one end of the long rod is fixedly connected to a mounting block, and baffles are fixedly connected to the surfaces of the two mounting blocks, and the end of the long rod away from the mounting block is fixedly connected to a setting block, and a sliding groove is provided on the surface of the setting block, and an L-shaped frame is fixedly connected to the surface of the slide, and an insertion rod is slidably inserted in the L-shaped frame, and one end of the insertion rod is fixedly connected to the placement block.

[0015] The effect achieved by the above components is: by setting the adjustment device, the operation panel is prevented from being accidentally touched, thereby avoiding the situation where the staff accidentally touches the operation panel buttons and causes material damage during the installation of various condensation tubes and the reactor body, thereby improving the stability of the device.

[0016] Preferably, the arc surface of the insertion rod is sleeved with a first spring, and two ends of the first spring are respectively fixedly connected to the placement block and the L-shaped frame.

[0017] The effect achieved by the above components is that the elastic force of the first spring drives the insertion rod to automatically insert into the setting block slide groove, thereby improving the quickness of the device.

[0018] Preferably, a second spring is fixedly connected to the inner surface of the slide, and one end of the second spring is fixedly connected to the mounting block.

[0019] The effects achieved by the above components are: the elastic force of the second spring drives the installation block to move, the installation block drives the long rod to move, and the installation block drives the baffle to open automatically, thereby improving the convenience of the device.

[0020] In summary, the beneficial effects of the utility model are:

[0021] 1. In the utility model, by setting a protective device, the effect of protecting the discharge port is achieved, which prevents dust or impurities in the outside air from adhering to the inner cavity of the discharge port, thereby preventing it from being easily contaminated, resulting in a decrease in the purity and quality of the product, and improving the practicability of the device.

[0022] 2. In the utility model, by setting the adjustment device, the effect of preventing the operation panel from being accidentally touched is achieved, which avoids the situation where the staff accidentally touches the operation panel buttons and causes material damage during the installation of various condensation tubes and the reactor body, and improves the stability of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;

[0024] Figure 2 It is a bottom view of the utility model;

[0025] Figure 3 It is a structural schematic diagram of the protective device in the utility model;

[0026] Figure 4 It is a structural schematic diagram of the regulating device in the utility model;

[0027] Figure 5 For the utility model Figure 4 Enlarged view of point A.

[0028] Legend: 1. Fixed frame; 2. Reactor body; 3. Discharge port; 4. Operation panel; 5. Protective device; 501. Bracket; 502. Round rod; 503. Connecting plate; 504. Protective cover; 505. L-shaped plate; 506. Screw; 507. Limit block; 508. Torsion spring; 509. Slide bar; 510. Handle; 6. Adjustment device; 601. Slide; 602. Long rod; 603. Mounting block; 604. Baffle; 605. Setting block; 606. L-shaped frame; 607. Insert rod; 608. Placement block; 609. First spring; 610. Second spring. DETAILED DESCRIPTION

[0029] Reference Figure 1 and Figure 2 As shown, the utility model provides a technical solution: a filtering reactor for polypeptide synthesis with a protective structure, comprising a fixing frame 1, the inner surface of the fixing frame 1 is fixedly connected to a reactor body 2, a discharge port 3 is installed on the surface of the reactor body 2, an operation panel 4 is installed on the surface of the fixing frame 1, and a protective device 5 is provided on the surface of the discharge port 3. By providing the protective device 5, the discharge port 3 is protected, and dust or impurities in the outside air are prevented from adhering to the inner cavity of the discharge port 3, which is easily contaminated, resulting in a decrease in the purity and quality of the product, thereby improving the practicability of the device. Adjustment devices 6 are provided on both sides of the operation panel 4. By providing the adjustment device 6, the operation panel 4 is prevented from being accidentally touched, thereby preventing the staff from accidentally touching the buttons of the operation panel 4 during the installation of various condensation tubes and the reactor body 2, thereby improving the stability of the device.

[0030] The specific settings and functions of the protective device 5 and the regulating device 6 are described in detail below.

[0031] Reference Figure 3As shown, in this embodiment: the protective device 5 includes a bracket 501, the bracket 501 is fixedly connected to the surface of the discharge port 3, the inner surface of the bracket 501 is fixedly connected to a round rod 502, the arc surface of the round rod 502 is rotatably connected to a connecting plate 503, one side of the connecting plate 503 is fixedly connected to a protective cover 504, the surface of the discharge port 3 is fixedly connected to an L-shaped plate 505, the L-shaped plate 505 has an internal thread inserted with a screw 506, one end of the screw 506 is rotatably connected to a limiting block 507, a sliding rod 509 is slidably inserted in the L-shaped plate 505, and one end of the sliding rod 509 is fixedly connected to the limiting block 507. The screw rod 506 rotates in the L-shaped plate 505, the screw rod 506 drives the limit block 507 to move, and the limit block 507 drives the slide bar 509 to slide in the L-shaped plate 505, so as to avoid the limit block 507 rotating with the rotation of the screw rod 506, thereby improving the stability of the device. The arc surface of the round rod 502 is covered with two torsion springs 508, and the two ends of the torsion spring 508 are respectively fixedly connected to the bracket 501 and the connecting plate 503. Until the limit block 507 does not block the protective cover 504, the torsion of the torsion spring 508 drives the connecting plate 503 to rotate on the arc surface of the round rod 502, and the connecting plate 503 drives the protective cover 504 to rotate automatically and maintain the position state, thereby improving the convenience of the device. The end of the screw rod 506 away from the limit block 507 is fixedly connected with a handle 510, and the surface of the handle 510 has a plurality of convex points. The handle 510 is rotated to drive the screw rod 506 to rotate in the L-shaped plate 505 , and the screw rod 506 drives the limit block 507 to move, so that the screw rod 506 can be rotated quickly and accurately to control the position of the limit block 507 during work.

[0032] Reference Figure 4 and Figure 5As shown, specifically, the adjustment device 6 includes two slides 601, and the two slides 601 are fixedly connected to both sides of the operation panel 4. A long rod 602 is slidably inserted in the two slides 601, one end of the long rod 602 is fixedly connected to a mounting block 603, and the surfaces of the two mounting blocks 603 are fixedly connected to a baffle 604, and the end of the long rod 602 away from the mounting block 603 is fixedly connected to a setting block 605, and a sliding groove is provided on the surface of the setting block 605, and an L-shaped frame 606 is fixedly connected to the surface of the slide 601, and an insertion rod 607 is slidably inserted in the L-shaped frame 606, and one end of the insertion rod 607 is fixedly connected to a placement block 608, and the arc surface of the insertion rod 607 is sleeved with a first spring 609, and the two ends of the first spring 609 are respectively fixedly connected to the placement block 608 and the L-shaped frame 606. Pushing the baffle 604 drives the long rod 602 to slide in the slide 601, and the long rod 602 drives the installation block 603 to move, and the long rod 602 drives the setting block 605 to move, until the setting block 605 is squeezed with the insertion rod 607, at which time the first spring 609 is in a stretched state, until the insertion rod 607 is aligned with the slide groove of the setting block 605, the elastic force of the first spring 609 drives the insertion rod 607 to automatically insert into the slide groove of the setting block 605, thereby improving the convenience of the device, and the inner surface of the slide 601 is fixedly connected with the second spring 610, one end of the second spring 610 is fixedly connected with the installation block 603. Pulling the placement block 608 drives the insertion rod 607 to slide in the L-shaped frame 606, until the insertion rod 607 is separated from the slide groove of the setting block 605, the elastic force of the second spring 610 drives the installation block 603 to move, the installation block 603 drives the long rod 602 to move, and the installation block 603 drives the baffle 604 to open automatically, thereby improving the convenience of the device.

[0033] Working principle: when the staff needs to block the discharge port 3, the protective cover 504 is pulled to drive the connecting plate 503 to rotate on the arc surface of the round rod 502, and the handle 510 is turned to drive the screw 506 to rotate in the L-shaped plate 505, and the screw 506 drives the limit block 507 to move until the limit block 507 blocks the baffle 604. When the protective cover 504 needs to be opened, the handle 510 is turned to drive the screw 506 to rotate in the L-shaped plate 505, and the screw 506 drives the limit block 507 to move until the limit block 507 does not block the protective cover 504. The torsion of the torsion spring 508 drives the connecting plate 503 to rotate on the arc surface of the round rod 502, and the connecting plate 503 drives the protective cover 504 to rotate and automatically open, thereby achieving the effect of protecting the discharge port 3, avoiding dust or impurities in the outside air from adhering to the inner cavity of the discharge port 3, which is easily contaminated, resulting in a decrease in the purity and quality of the product, thereby improving the practicability of the device.

[0034] When the staff needs to block the operation panel 4, the baffle 604 is pushed to drive the long rod 602 to slide in the slide 601, and the long rod 602 drives the installation block 603 to move, and the long rod 602 drives the setting block 605 to move until the setting block 605 is squeezed with the insertion rod 607. At this time, the first spring 609 is in a stretched state. Until the insertion rod 607 is aligned with the sliding groove of the setting block 605, the elastic force of the first spring 609 drives the insertion rod 607 to automatically insert into the sliding groove of the setting block 605. When the baffle 604 needs to be opened, By pulling the placement block 608, the insertion rod 607 is driven to slide in the L-shaped frame 606 until the insertion rod 607 is disengaged from the slide groove of the setting block 605, and the elastic force of the second spring 610 drives the installation block 603 to move, and the installation block 603 drives the long rod 602 to move, and the installation block 603 drives the baffle 604 to open automatically, thereby achieving the effect of preventing accidental touching of the operation panel 4, avoiding the situation in which the staff accidentally touches the buttons of the operation panel 4 and causes material damage during the installation of various condensation tubes and the reactor body 2, thereby improving the stability of the device.

[0035] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

Claims

1. A filtering reactor for peptide synthesis with a protective structure, comprising a fixing frame (1), characterized in that: The inner surface of the fixing frame (1) is fixedly connected to a reactor body (2), a discharge port (3) is installed on the surface of the reactor body (2), an operation panel (4) is installed on the surface of the fixing frame (1), a protective device (5) is provided on the surface of the discharge port (3), the protective device (5) comprises a bracket (501), the bracket (501) is fixedly connected to the surface of the discharge port (3), a round rod (502) is fixedly connected to the inner surface of the bracket (501), a connecting plate (503) is rotatably connected to the circular arc surface of the round rod (502), a protective cover (504) is fixedly connected to one side of the connecting plate (503), an L-shaped plate (505) is fixedly connected to the surface of the discharge port (3), a screw rod (506) is inserted into the inner thread of the L-shaped plate (505), and one end of the screw rod (506) is rotatably connected to a limiting block (507).

2. The filtering reactor for polypeptide synthesis with a protective structure according to claim 1, characterized in that: A sliding rod (509) is slidably inserted into the L-shaped plate (505), and one end of the sliding rod (509) is fixedly connected to the limiting block (507).

3. The filtering reactor for polypeptide synthesis with a protective structure according to claim 1, characterized in that: The arc surface of the round rod (502) is sleeved with two torsion springs (508), and the two ends of the torsion spring (508) are respectively fixedly connected to the bracket (501) and the connecting plate (503).

4. The filtering reactor for polypeptide synthesis with a protective structure according to claim 1, characterized in that: One end of the screw rod (506) away from the limiting block (507) is fixedly connected to a handle (510), and a surface of the handle (510) has a plurality of protrusions.

5. The filtering reactor for peptide synthesis with a protective structure according to claim 1, characterized in that: Adjustment devices (6) are provided on both sides of the operation panel (4), and the adjustment device (6) comprises two slides (601), and the two slides (601) are fixedly connected to both sides of the operation panel (4), and a long rod (602) is slidably inserted in each of the two slides (601), and one end of the long rod (602) is fixedly connected to a mounting block (603), and the surfaces of the two mounting blocks (603) are fixedly connected to a baffle (604), and one end of the long rod (602) away from the mounting block (603) is fixedly connected to a setting block (605), and a sliding groove is provided on the surface of the setting block (605), and an L-shaped frame (606) is fixedly connected to the surface of the slide (601), and an insertion rod (607) is slidably inserted in the L-shaped frame (606), and one end of the insertion rod (607) is fixedly connected to a placement block (608).

6. The filtering reactor for peptide synthesis with a protective structure according to claim 5, characterized in that: The arc surface of the insert rod (607) is sleeved with a first spring (609), and the two ends of the first spring (609) are respectively fixedly connected to the placement block (608) and the L-shaped frame (606).

7. The filtering reactor for peptide synthesis with a protective structure according to claim 5, characterized in that: A second spring (610) is fixedly connected to the inner surface of the slide (601), and one end of the second spring (610) is fixedly connected to the mounting block (603).

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