Cell culture plate
By designing hollow cell culture plates and using structures such as sealing rings and fixing frames, cleaning difficulties and pollution risks caused by the design of the depression structure is solved, and higher cleaning convenience and safety are achieved.
Patent Information
- Application Number
- CN202421100097.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-20
- Publication Date
- 2025-02-21
- Estimated Expiration
- 2034-05-20
AI Technical Summary
In the prior art, the culture tanks of cell culture plates are designed as recessed structures, which make it difficult to clean and increase the risk of contamination and cross-infection.
A hollow cell culture plate is designed to ensure the sealing of the culture tank by setting up a sealing ring, a fixing frame and a threaded knob. The cleaning and operation of the culture tank is facilitated by placing blocks and connecting plates.
Through the hollowed-out design and sealing structure, the cleaning convenience of cell culture plates is improved, the risks of contamination and cross-infection are reduced, and the safety and effectiveness of cell culture are ensured.
Smart Images
Figure CN222512935U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell culture, in particular to a cell culture plate. Background Art
[0002] The cell culture plate has good transparency, is non-toxic and sterile, and can promote the growth and reproduction of primary cells such as nerve cells, passage cells such as tumor cells and other animal and human cells. The commonly used cell culture plate is an integrally formed porous structure with a plurality of fixed unit holes. During cell culture, the culture personnel place a cell culture plate with a plurality of unit holes in the same cell culture box so that the same type of cells can grow and reproduce in a unified and balanced environment. In the long-term culture process of the cell culture plate of the prior art, when operating a single culture tank, whether it is adding drugs or changing liquid, the entire plate cover needs to be opened, so that a large area of the culture plate is exposed to the outside world, which can easily contaminate the culture in other culture tanks.
[0003] Prior art patent CN214937535U discloses a cell culture plate, comprising a cell culture plate seat, wherein the upper end surface of the cell culture plate seat is provided with a plurality of evenly distributed culture grooves, the two opposite sides of the upper end surface of the cell culture plate seat are provided with T-shaped slide grooves, the upper end surface of the cell culture plate seat is also provided with a locking groove, a cell culture plate cover is provided above the cell culture plate seat, a T-shaped slider slidably connected to the T-shaped slide groove is fixedly connected to the lower end of the cell culture plate cover, a fastening bolt is threadedly connected to the cell culture plate cover, and the fastening bolt matches the locking groove. The cell culture plate provided by the prior art can effectively prevent other independent culture grooves from being exposed to the outside world and being contaminated.
[0004] However, in the above-mentioned prior art, since the culture tank of the cell culture plate is designed in a concave structure, it is difficult to clean, which easily increases the risk of contamination and cross infection. Utility Model Content
[0005] The utility model aims to provide a cell culture plate, aiming to solve the technical problem in the prior art that the culture tank of the cell culture plate is designed in a concave structure, which makes it difficult to clean and easily causes an increased risk of contamination and cross infection.
[0006] To achieve the above-mentioned purpose, the utility model adopts a cell culture plate, including a cover plate, a base and a fixing mechanism, wherein fasteners are arranged at both ends of the cover plate, a plurality of sealing covers are arranged above the cover plate, two convex blocks are arranged below the cover plate, fastening grooves are arranged at both ends of the base, convex grooves are arranged on both sides of the base, a plurality of culture grooves are arranged on the end surface of the base, a sealing groove is arranged below the culture groove, a placement block is slidably arranged in the culture groove, a connecting disk is arranged below the placement block, and the connecting disk is located in the sealing groove, and the cover plate is slidably connected to the base , and is located above the base, and the convex block is located in the convex groove, the fastener is plugged into the base and is located in the corresponding fastening groove, the fixing mechanism includes a plurality of sealing rings, a fixing frame and a plurality of threaded knobs, a plurality of the sealing rings are respectively slidably connected with the corresponding placement blocks, and are sleeved on the placement blocks, and are held between the sealing groove and the connecting plate, the fixing frame is fixedly connected to the base through the threaded knob, and is located below the base, and a plurality of the connecting plates are respectively fixedly connected to the fixing frame, and are located above the fixing frame.
[0007] Wherein, the fixing frame includes a vertical rod and two cross rods, the vertical rod is fixedly connected to the corresponding cross rod and is located between the two cross rods, the vertical rod is also fixedly connected to the base through the threaded knob and is located below the base, the two cross rods are fixedly connected to the base through the threaded knob and are located below the base, and the multiple connecting plates are respectively fixedly connected to the corresponding cross rods and are located on the cross rods.
[0008] Wherein, the fastener includes a limit plate, a spring and a fastening rod, and the cover plate has movable cavities at both ends. The limit plate is fixedly connected to the fastening rod and sleeved on the fastening rod. The limit plate is also slidably connected to the cover plate and is located in the movable cavity. The spring is sleeved on the fastening rod and is supported between the movable cavity and the limit plate. The fastening rod is slidably connected to the cover plate and is located in the movable cavity and passes through both ends of the movable cavity. The fastening rod is also plugged into the base and is located in the corresponding fastening groove.
[0009] Wherein, the cell culture plate further comprises a plurality of supporting mechanisms, and the plurality of supporting mechanisms are respectively fixedly connected to the base and are located at four bottom corners of the base.
[0010] Wherein, the cell culture plate further includes two limiting members, and the two limiting members are respectively arranged on both sides of the cover plate and the base.
[0011] Among them, the supporting mechanism includes an anti-slip pad, a screw rod and a supporting leg. There is a threaded groove at the bottom of the supporting leg. The anti-slip pad is fixedly connected to the screw rod and is located below the screw rod. The screw rod is threadedly connected to the supporting leg and is located in the threaded groove. The supporting leg is fixedly connected to the base and is located at the bottom corner of the base.
[0012] Among them, the limiting part includes an elastic reel box and a fixed block, a limiting rope is arranged in the elastic reel box, the elastic reel box is fixedly connected to the cover plate and is located on one side of the cover plate, and the limiting rope is fixedly connected to the fixed block and is located above the fixed block, and the fixed block is fixedly connected to the base and is located on one side of the base.
[0013] The utility model provides a cell culture plate, comprising a cover plate, a base and a fixing mechanism, wherein fasteners are arranged at both ends of the cover plate, a plurality of sealing covers are arranged above the cover plate, two convex blocks are arranged below the cover plate, fastening grooves are arranged at both ends of the base, convex grooves are arranged at both sides of the base, a plurality of culture grooves are arranged at the end face of the base, a sealing groove is arranged below the culture grooves, a placement block is slidably arranged in the culture grooves, a connecting disk is arranged below the placement block, the fixing mechanism comprises a plurality of sealing rings, a fixing frame and a plurality of threaded knobs, and the culture grooves are arranged in a hollow shape so as to facilitate subsequent cleaning, thereby avoiding the increased risk of contamination and cross infection, and the placement block and the connecting disk are arranged so as to facilitate the culture groove to culture cells normally, and finally the sealing between the connecting disk and the sealing groove is improved by the arrangement of the sealing ring and the fixing frame. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0015] Figure 1 It is a side view of the first embodiment of the utility model.
[0016] Figure 2 The utility model Figure 1 Section view along line AA.
[0017] Figure 3 The utility model Figure 1 Sectional view along line BB.
[0018] Figure 4 The utility model Figure 1 Sectional view along the CC line.
[0019] Figure 5 It is a three-dimensional stereogram of the second embodiment of the utility model.
[0020] Figure 6 It is a side view of the second embodiment of the utility model.
[0021] Figure 7 The utility model Figure 6 Sectional view along line DD.
[0022] 101-cover, 102-base, 103-sealing cover, 104-convex block, 105-fastening groove, 106-convex groove, 107-culture groove, 108-sealing groove, 109-placing block, 110-connecting plate, 111-sealing ring, 112-threaded knob, 113-vertical rod, 114-cross rod, 115-limiting plate, 116-spring, 117-fastening rod, 118-movable cavity, 201-anti-slip pad, 202-screw, 203-support leg, 204-threaded groove, 205-elastic reel box, 206-fixing block, 207-limiting rope. DETAILED DESCRIPTION
[0023] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.
[0024] First embodiment:
[0025] See also Figure 1 to Figure 4 ,in Figure 1 is a side view of the first embodiment of the utility model, Figure 2 The utility model Figure 1 The cross-sectional view along the AA line. Figure 3 The utility model Figure 1 The cross-sectional view of the BB line. Figure 4 The utility model Figure 1 Sectional view along the CC line.
[0026] The utility model provides a cell culture plate, comprising a cover plate 101, a base 102 and a fixing mechanism, wherein the fixing mechanism comprises a plurality of sealing rings 111, a fixing frame and a plurality of threaded knobs 112, the fixing frame comprises a vertical rod 113 and two horizontal rods 114, and the fastener comprises a limit piece 115, a spring 116 and a fastening rod 117. The above-mentioned scheme solves the technical problem that the culture groove 107 of the cell culture plate is designed with a concave structure, which makes it difficult to clean and easily causes an increased risk of contamination and cross infection.
[0027] According to this specific embodiment, fasteners are provided at both ends of the cover plate 101, a plurality of sealing covers 103 are provided above the cover plate 101, two convex blocks 104 are provided below the cover plate 101, fastening grooves 105 are provided at both ends of the base 102, convex grooves 106 are provided on both sides of the base 102, a plurality of culture grooves 107 are provided on the end surface of the base 102, a sealing groove 108 is provided below the culture groove 107, a placement block 109 is provided in a sliding manner in the culture groove 107, a connection plate 110 is provided below the placement block 109, and the The connecting plate 110 is located in the sealing groove 108, the cover plate 101 is slidably connected to the base 102 and is located above the base 102, and the convex block 104 is located in the convex groove 106, the fastener is plugged into the base 102 and is located in the corresponding fastening groove 105. During long-term culture, when it is necessary to add medicine or change the liquid, the sealing cover 103 can be opened directly to add medicine or change the liquid for the corresponding independent culture tank 107 in the base 102, so as to prevent other culture tanks 107 from being exposed to the outside and contaminated.
[0028] Among them, multiple sealing rings 111 are respectively slidably connected to the corresponding placement blocks 109, and are sleeved on the placement blocks 109, and are held between the sealing groove 108 and the connecting plate 110. The fixing frame is fixedly connected to the base 102 through the threaded knob 112, and is located below the base 102. Multiple connecting plates 110 are respectively fixedly connected to the fixing frame and are located above the fixing frame. By setting the culture tank 107 to be hollow, subsequent cleaning can be facilitated, thereby avoiding the increased risk of contamination and cross infection. By setting the placement block 109 and the connecting plate 110, the culture tank 107 can be facilitated to culture cells normally. Finally, the sealing between the connecting plate 110 and the sealing groove 108 can be improved by setting the sealing ring 111 and the fixing frame.
[0029] Secondly, the vertical rod 113 is fixedly connected to the corresponding cross rod 114 and is located between the two cross rods 114. The vertical rod 113 is also fixedly connected to the base 102 through the threaded knob 112 and is located below the base 102. The two cross rods 114 are fixedly connected to the base 102 through the threaded knob 112 and are located below the base 102. The multiple connecting plates 110 are respectively fixedly connected to the corresponding cross rods 114 and are located on the cross rods 114. The arrangement of the vertical rod 113 and the cross rod 114 can facilitate the support of the multiple connecting plates 110, thereby improving the sealing between the connecting plates 110 and the sealing groove 108.
[0030] Again, both ends of the cover plate 101 have an active cavity 118, the limiting piece 115 is fixedly connected to the fastening rod 117 and sleeved on the fastening rod 117, the limiting piece 115 is also slidably connected to the cover plate 101 and is located in the active cavity 118, the spring 116 is sleeved on the fastening rod 117 and abuts between the active cavity 118 and the limiting piece 115, the fastening rod 117 is slidably connected to the cover plate 101 and is located in the active cavity 118, and passes through the active cavity 118. At both ends of 8, the fastening rod 117 is also plugged into the base 102 and is located in the corresponding fastening groove 105. By pulling the fastening rod 117, the fastening rod 117 is moved out of the fastening groove 105, so that the cover 101 can be easily removed from the base 102. Then the fastening rod 117 is loosened so that the fastening rod 117 is plugged into another fastening groove 105 under the action of the spring 116, so as to facilitate the cleaning of the multiple culture tanks 107 on the base 102.
[0031] When using the utility model to clean the culture tank 107, the threaded knob 112 is removed, and then the fixing frame is removed. At the same time, the fixing frame drives the multiple connecting plates 110 to move, and the placement block 109 is moved out of the culture tank 107 under the action of the connecting plate 110. At this time, the culture tank 107 can be cleaned, and the surface of the placement block 109 can also be directly cleaned. The culture tank 107 is set to be hollow, which can facilitate subsequent cleaning, thereby avoiding the increased risk of contamination and cross infection.
[0032] The second embodiment is:
[0033] Based on the first embodiment, please refer to Figure 5 to Figure 7 ,in Figure 5 It is a three-dimensional stereogram of the second embodiment of the utility model. Figure 6 is a side view of the second embodiment of the utility model, Figure 7 The utility model Figure 6 Sectional view along line DD.
[0034] The utility model provides a cell culture plate, which also includes a plurality of supporting mechanisms and two limiting members. The supporting mechanisms include an anti-slip pad 201 , a screw rod 202 and a supporting leg 203 , and the limiting members include an elastic reel box 205 and a fixing block 206 .
[0035] According to this specific embodiment, the plurality of support mechanisms are respectively fixedly connected to the base 102 and are located at the four bottom corners of the base 102. The base 102 can be easily supported by the support mechanisms, thereby facilitating the use of the cell culture plate.
[0036] The two limiting members are respectively arranged on both sides of the cover plate 101 and the base 102 , and the limiting members can effectively prevent the cover plate 101 from being completely pushed away from the base 102 .
[0037] Among them, there is a thread groove 204 at the bottom of the support leg 203, the anti-slip pad 201 is fixedly connected to the screw rod 202 and is located below the screw rod 202, the screw rod 202 is threadedly connected to the support leg 203 and is located in the thread groove 204, the support leg 203 is fixedly connected to the base 102 and is located at the bottom corner of the base 102, the grip of the cell culture plate can be improved by the anti-slip pad 201, and the screw rod 202 can facilitate the subsequent replacement of the damaged anti-slip pad 201.
[0038] Among them, a limiting rope 207 is arranged in the elastic reel box 205, the elastic reel box 205 is fixedly connected to the cover plate 101 and is located on one side of the cover plate 101, and the limiting rope 207 is fixedly connected to the fixed block 206 and is located above the fixed block 206, the fixed block 206 is fixedly connected to the base 102 and is located on one side of the base 102, the limiting rope 207 can be easily collected through the elastic reel box 205, thereby facilitating the lengthening and shortening of the limiting rope 207.
[0039] When using a cell culture plate of the present embodiment, the base 102 can be supported by the supporting mechanism, thereby facilitating the use of the cell culture plate. The limiting member can effectively prevent the cover 101 from being completely pushed away from the base 102. The anti-slip pad 201 can improve the grip of the cell culture plate. Meanwhile, the screw 202 can facilitate the subsequent replacement of the damaged anti-slip pad 201. The elastic reel box 205 can facilitate the collection of the limiting rope 207, thereby facilitating the lengthening and shortening of the limiting rope 207.
[0040] The above disclosure is only a preferred embodiment of the present invention, and certainly cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiment and equivalent changes made according to the claims of the present invention still fall within the scope covered by the utility model.
Claims
1. A cell culture plate, comprising a cover plate and a base, wherein fasteners are arranged at both ends of the cover plate, a plurality of sealing covers are arranged above the cover plate, two convex blocks are arranged below the cover plate, fastening grooves are arranged at both ends of the base, convex grooves are arranged on both sides of the base, a plurality of culture grooves are arranged on the end face of the base, a sealing groove is arranged below the culture groove, a placement block is slidably arranged in the culture groove, a connecting disk is arranged below the placement block, and the connecting disk is located in the sealing groove, the cover plate is slidably connected to the base and is located above the base, and the convex block is located in the convex groove, the fastener is plugged into the base and is located in the corresponding fastening groove, characterized in that Also includes a fixing mechanism; The fixing mechanism includes a plurality of sealing rings, a fixing frame and a plurality of threaded knobs. The plurality of sealing rings are respectively slidably connected to the corresponding placement blocks, and are sleeved on the placement blocks and are held between the sealing groove and the connecting plate. The fixing frame is fixedly connected to the base through the threaded knob and is located below the base, and the plurality of connecting plates are respectively fixedly connected to the fixing frame and are located above the fixing frame.
2. The cell culture plate according to claim 1, characterized in that The fixing frame includes a vertical rod and two cross rods, the vertical rod is fixedly connected to the corresponding cross rod and is located between the two cross rods, the vertical rod is also fixedly connected to the base through the threaded knob and is located below the base, the two cross rods are fixedly connected to the base through the threaded knob and are located below the base, and the multiple connecting plates are respectively fixedly connected to the corresponding cross rods and are located on the cross rods.
3. The cell culture plate according to claim 2, characterized in that The fastener includes a limit plate, a spring and a fastening rod. Both ends of the cover plate have movable cavities. The limit plate is fixedly connected to the fastening rod and sleeved on the fastening rod. The limit plate is also slidably connected to the cover plate and is located in the movable cavity. The spring is sleeved on the fastening rod and is supported between the movable cavity and the limit plate. The fastening rod is slidably connected to the cover plate and is located in the movable cavity and passes through both ends of the movable cavity. The fastening rod is also plugged into the base and is located in the corresponding fastening groove.
4. The cell culture plate according to claim 3, characterized in that The cell culture plate further comprises a plurality of supporting mechanisms, which are respectively fixedly connected to the base and are located at four bottom corners of the base.
5. The cell culture plate according to claim 4, characterized in that The cell culture plate further comprises two limiting members, which are respectively arranged on both sides of the cover plate and the base.
6. The cell culture plate according to claim 5, characterized in that The support mechanism includes an anti-skid pad, a screw rod and a support leg. A threaded groove is provided below the support leg. The anti-skid pad is fixedly connected to the screw rod and is located below the screw rod. The screw rod is threadedly connected to the support leg and is located in the threaded groove. The support leg is fixedly connected to the base and is located at the bottom corner of the base.
7. The cell culture plate according to claim 6, characterized in that The limiting member includes an elastic reel box and a fixed block, a limiting rope is arranged in the elastic reel box, the elastic reel box is fixedly connected to the cover plate and is located on one side of the cover plate, and the limiting rope is fixedly connected to the fixed block and is located above the fixed block, and the fixed block is fixedly connected to the base and is located on one side of the base.