Magnetic frame

By designing a magnetic stand that includes small tube separation unit and large tube separation unit, the problem that the existing magnetic stand cannot adapt to the centrifugal tubes of different specifications is solved, and effective magnetic separation of centrifugal tubes of different specifications is achieved, which significantly improves the Its versatility.

CN222518835UActive Publication Date: 2025-02-25BIOKEYSTONE TECH CO LTD
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Patent Information

Application Number
CN202420440613.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-07
Publication Date
2025-02-25
Estimated Expiration
2034-03-07

AI Technical Summary

Technical Problem

The existing magnetic racks cannot adapt to centrifuge tubes of different specifications, resulting in poor versatility and cannot meet the needs of different experimental conditions.

Method used

A magnetic rack is designed, including a small tube separation unit and a large tube separation unit. Through flexible assembly, it can adapt to different specifications of centrifuge tubes such as 1.5mL and 50mL to achieve magnetic separation of centrifuge tubes of different sizes.

Benefits of technology

This magnetic rack can place small centrifugal tubes without assembling large tube separation units, or large centrifugal tubes can be assembling large tube separation units. It is suitable for two different test conditions, significantly improving its versatility.

✦ Generated by Eureka AI based on patent content.

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Abstract

A magnetic frame comprises a small pipe separation unit, a large pipe separation unit and a magnetic unit. The small tube separation unit comprises a pair of C-shaped frames which are oppositely arranged and a pair of vertical rods which are arranged at the two ends of the C-shaped frames, and a plurality of bottom tube holes which are through up and down are formed in the transverse edges of the C-shaped frames in an array mode and used for containing small centrifugal tubes. The large tube separation unit is assembled at the upper end of the small tube separation unit and comprises a frame plate, two columns of square grooves penetrating up and down are formed in the frame plate, a vertical plate is further arranged at the upper end of the frame plate, a top plate is arranged at the upper end of the vertical plate, and a plurality of tube jacking holes are formed in the top plate and used for containing large centrifugal tubes. The magnetic unit is vertically and slidably arranged at one end of the small pipe separation unit and comprises a square frame part slidably matched with the outer ends of the two vertical rods, and a plurality of magnetic blocks matched with the square grooves are arranged at the upper end of the square frame part. The magnetic frame can be used for placing various centrifugal tubes with two different specifications and purposes, and is high in universality.
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Description

Technical Field

[0001] The utility model relates to the technical field of universal magnetic frames, in particular to a magnetic frame. Background Art

[0002] Magnetic separation technology is increasingly used in the separation of biological molecules, drugs and other materials. The general process of magnetic separation is to add magnetic materials that can bind to the sample to be separated into a centrifuge tube containing the sample solution to be separated. After the magnetic material is fully combined with the sample to be separated, an external magnetic field is applied to the outside of the centrifuge tube through a magnetic frame. Under the action of the magnetic field, the magnetic material bound to the sample to be separated is enriched from the solution, thereby achieving sample separation.

[0003] However, there are many types of centrifuge tubes used for magnetic separation, including 1.5mL or 2mL small centrifuge tubes and 50mL or 100mL large centrifuge tubes. Generally speaking, small centrifuge tubes are usually used for small-scale experiments, such as molecular biology experiments. Small centrifuge tubes can easily accommodate small amounts of reagents or samples, such as DNA, RNA, proteins and other biological molecules. Large centrifuge tubes are used for larger-scale experiments, such as cell culture, protein precipitation, etc., and can accommodate more reagents or samples. However, existing magnetic racks cannot be used to place centrifuge tubes of different specifications, and their versatility is poor. Utility Model Content

[0004] In view of the above defects, the utility model provides a magnetic rack which can hold various centrifuge tubes of two different specifications and uses and has strong versatility.

[0005] In order to achieve the purpose of this utility model, the following technologies are proposed:

[0006] A magnetic frame, comprising:

[0007] The small tube separation unit comprises a pair of C-shaped frames arranged opposite to each other and a pair of vertical rods arranged at both ends of the C-shaped frames, and a plurality of bottom tube holes penetrating vertically are arranged in a horizontal array on the C-shaped frames for placing small centrifuge tubes;

[0008] The large tube separation unit is assembled on the upper end of the small tube separation unit, and comprises a frame plate, on which two rows of square grooves are arranged running vertically, a vertical plate is arranged on the upper end of the frame plate, a top plate is arranged on the upper end of the vertical plate, and a plurality of top tube holes are arranged on the top plate for placing large centrifuge tubes;

[0009] The magnetic unit is vertically and slidably arranged at one end of the small tube separation unit, and comprises a square frame part which is slidably matched with the outer ends of the two vertical rods, and a plurality of magnetic blocks which match the square grooves are arranged at the upper end of the square frame part.

[0010] Furthermore, a bottom plate is connected between the lower ends of the inner side surfaces of the lower horizontal sides of the two C-shaped frames, and two vertical rods are respectively arranged at both ends of the bottom plate.

[0011] Furthermore, a plurality of bottom limit rings are arranged in an array on the upper end surface of the lower horizontal side of the C-shaped frame to limit the bottom end of the small centrifuge tube.

[0012] Furthermore, a plurality of insertion holes are arranged in an array on the upper end surface of the upper horizontal side of the C-shaped frame, and a plurality of insertion rods respectively matching with the insertion holes are arranged on the lower end of the frame plate.

[0013] Furthermore, the small tube separation unit is also provided with a plurality of transverse grooves penetrating on both sides, the transverse grooves penetrating the upper end surfaces of the two C-shaped frames, and blocks are installed in the transverse grooves for mounting the frame plates on the upper ends thereof.

[0014] Furthermore, the frame plate is provided with a plurality of top limit rings arranged in two rows for limiting the bottom end of the large centrifuge tube, and the top tube hole matches the top limit ring.

[0015] Furthermore, the vertical plate is located at the upper end between the two rows of square grooves.

[0016] Furthermore, a handle is provided at one end of the square frame.

[0017] The beneficial effects of this technical solution are:

[0018] It is possible not to assemble the large tube separation unit and place a small centrifuge tube in the small tube separation unit, or it is possible to assemble the large tube separation unit and place a large centrifuge tube. It is suitable for two different test conditions and has strong versatility. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 An overall stereoscopic view of the large tube separation unit when assembled in an embodiment of the present application is shown.

[0020] Figure 2 A stereoscopic view of an embodiment of the present application without a large tube separation unit is shown.

[0021] Figure 3 An exploded view of an embodiment of the present application is shown. DETAILED DESCRIPTION

[0022] The present application is further described below in conjunction with the accompanying drawings and embodiments.

[0023] like Figure 1~Figure 3 A magnetic rack shown includes a small tube separation unit 1, a large tube separation unit 2, and a magnetic unit 3.

[0024] The small tube separation unit 1 includes a pair of C-shaped frames 11 arranged opposite to each other, a bottom plate 12 is connected between the lower ends of the inner side surfaces of the lower horizontal sides of the two C-shaped frames 11, and vertical rods 13 are respectively provided at both ends of the bottom plate 12. A plurality of bottom limit rings 14 are arranged in an array on the upper end surface of the lower horizontal side of the C-shaped frame 11 for limiting the bottom end of the small centrifuge tube 4. A plurality of bottom tube holes 15 penetrating from top to bottom are arranged in an array on the upper horizontal side of the C-shaped frame 11 for limiting the upper part of the small centrifuge tube 4. A plurality of jacks 16 are also arranged in an array on the upper end surface of the upper horizontal side of the C-shaped frame 11. The small tube separation unit 1 also has a plurality of transverse grooves 17 penetrating on both sides, the transverse grooves 17 penetrate the upper end surfaces of the two C-shaped frames 11, and a stop block 18 is assembled in the transverse groove 17. The stop block 18 includes a plurality of slot plates respectively slidably fitted in the transverse slots 17, and a connecting plate connected to the lower part of one end of each slot plate.

[0025] The large tube separation unit 2 is assembled on the upper end of the small tube separation unit 1, and includes a frame plate 21. The frame plate 21 is provided with a plurality of top limit rings 22 arranged in two rows for limiting the bottom end of the large centrifuge tube 5. Specifically, each top limit ring 22 is respectively arranged above a plurality of bottom tube holes 15. In the present embodiment, two bottom tube holes 15 correspond to each other below one top limit ring 22. A plurality of plug rods 23 respectively matching the plug holes 16 are provided at the lower end of the frame plate 21. Two rows of square grooves 24 running through the frame plate 21 are provided. A vertical plate 25 is also provided at the upper end of the frame plate 21. The vertical plate 25 is located at the upper end between the two rows of square grooves 24. A top plate 26 is provided at the upper end of the vertical plate 25. A plurality of top tube holes 27 respectively matching the top limit rings 22 are provided on the top plate 26 for limiting the upper part of the large centrifuge tube 5.

[0026] The magnetic unit 3 is vertically slidably arranged at one end of the small tube separation unit 1, including a square frame portion 31 that is slidably fitted on the outer ends of the two vertical rods 13, a handle 32 is provided at one end of the square frame portion 31, and a plurality of protruding rods are provided at the upper end of the square frame portion 31, and a magnetic block 33 matching the square groove 24 is provided on the protruding rod. When the magnetic unit 3 moves to the lower end, the square frame portion 31 is located on the bottom plate 12. When assembling the large tube separation unit 2, it is necessary to move the magnetic unit 3 to the upper end and insert the stop block 18 into the horizontal groove 17. At this time, the square frame portion 31 is clamped between the stop block 18 and the frame plate 21.

[0027] Working method:

[0028] In this embodiment, the small centrifuge tube 4 is a 1.5mL centrifuge tube, and the large centrifuge tube 5 is a 50mL centrifuge tube, so the bottom limit ring 14 and the bottom tube hole 15 are processed to match the size of the 1.5mL centrifuge tube, and the top limit ring 22 and the top tube hole 27 are processed to match the size of the 50mL centrifuge tube.

[0029] When the magnetic stand is used to magnetically separate the contents of the small centrifuge tube 4, the magnetic unit 3 is moved to the bottom, and the large tube separation unit 2 is not installed. Figure 2As shown, after a small centrifuge tube 4 is placed in each hole, a magnetic block 33 is provided at the lower side of each small centrifuge tube 4 to facilitate separation.

[0030] When the magnetic rack is used to magnetically separate the contents of the large centrifuge tube 5, the magnetic unit 3 is first raised, and then the insertion rod 23 is inserted into the insertion hole 16 to fix the frame plate 21, and the stop block 18 is inserted into the horizontal groove 17 so that the upper end thereof is against the square frame portion 31, so that the handle 32 does not need to be held all the time, and the magnetic block 33 passes through the square groove 24 to the upper side. Figure 1 As shown, after the large centrifuge tubes 5 are placed in each hole, there are magnetic blocks 33 at the lower side of each large centrifuge tube 5 to facilitate separation.

[0031] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A magnetic frame, characterized in that: include: A small tube separation unit (1) comprises a pair of C-shaped frames (11) arranged opposite to each other and a pair of vertical rods (13) arranged at both ends of the C-shaped frames (11); a plurality of bottom tube holes (15) extending vertically and horizontally through the C-shaped frames (11) are arranged in an array on the horizontal side thereof for accommodating small centrifuge tubes (4); The large tube separation unit (2) is assembled on the upper end of the small tube separation unit (1), and comprises a frame plate (21). The frame plate (21) is provided with two rows of square grooves (24) extending vertically therethrough. A vertical plate (25) is also provided on the upper end of the frame plate (21). A top plate (26) is provided on the upper end of the vertical plate (25). The top plate (26) is provided with a plurality of top tube holes (27) for placing the large centrifuge tubes (5); The magnetic unit (3) is vertically slidably disposed at one end of the small tube separation unit (1), and comprises a square frame portion (31) slidably fitted on the outer ends of the two vertical rods (13), wherein the upper end of the square frame portion (31) is provided with a plurality of magnetic blocks (33) matching the square grooves (24).

2. The magnetic frame according to claim 1, characterized in that: A bottom plate (12) is connected between the lower ends of the inner side surfaces of the lower horizontal sides of the two C-shaped frames (11), and two vertical rods (13) are respectively arranged at both ends of the bottom plate (12).

3. The magnetic frame according to claim 1, characterized in that: A plurality of bottom limit rings (14) are arranged in an array on the upper end surface of the lower horizontal side of the C-shaped frame (11) for limiting the bottom end of the small centrifuge tube (4).

4. The magnetic frame according to claim 1, characterized in that: A plurality of insertion holes (16) are arranged in an array on the upper end surface of the upper horizontal side of the C-shaped frame (11), and a plurality of insertion rods (23) respectively matching the insertion holes (16) are arranged on the lower end of the frame plate (21).

5. The magnetic frame according to claim 1, characterized in that: The small tube separation unit (1) is also provided with a plurality of transverse grooves (17) penetrating through both sides. The transverse grooves (17) penetrate the upper end surfaces of the two C-shaped frames (11). Abutment blocks (18) are installed in the transverse grooves (17) for mounting the frame plate (21) on the upper end thereof.

6. The magnetic frame according to claim 1, characterized in that: A plurality of top limit rings (22) arranged in two rows are provided on the frame plate (21) for limiting the bottom end of the large centrifuge tube (5), and the top tube hole (27) matches the top limit ring (22).

7. The magnetic frame according to claim 1, characterized in that: The vertical plate (25) is located at the upper end between the two rows of square grooves (24).

8. The magnetic frame according to claim 1, characterized in that: A handle (32) is provided at one end of the square frame portion (31).