Laboratory microplate reader

By designing anti-slip structure and support plate in the laboratory microplate reader, combining the open and closed structure and the moving plate, the clamping positioning of the sample plate is achieved, which solves the problem of inaccurate detection caused by inclination of the sample plate, improves detection accuracy and simplifies operation.

CN222539358UActive Publication Date: 2025-02-28ARMY MEDICAL UNIV
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Patent Information

Application Number
CN202421066475.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-16
Publication Date
2025-02-28
Estimated Expiration
2034-05-16

AI Technical Summary

Technical Problem

Existing laboratory microplate reader is prone to tilt during the positioning of the sample plate, resulting in inaccurate detection.

Method used

A laboratory microplate reader was designed, using a combination of anti-slip structure and support plate. Through the design of the open and closed structure and the moving plate, the clamping positioning of the sample plate is achieved to avoid tilting.

Benefits of technology

It effectively avoids the tilt of the sample plate during the inspection process, improves the accuracy of the inspection, and simplifies the operation process through the automatic storage function.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of ELISA detection equipment, and discloses a laboratory microplate reader, which comprises a microplate reader, the outer surface of the microplate reader is provided with an antiskid structure, the bottom wall of the inner cavity of the microplate reader is fixedly provided with a support plate, the support plate is provided with an opening and closing structure, the opening and closing structure is provided with a moving plate, and the moving plate is provided with a sliding plate. A sample plate is arranged on the moving plate, the moving plate is movably connected with an opening in the microplate reader, the anti-skid structure comprises a connecting plate, the connecting plate is fixedly connected with the outer surface of the microplate reader, a threaded short shaft is arranged in the connecting plate, a rotating block is fixedly mounted at one end of the threaded short shaft, and the other end of the threaded short shaft is fixedly connected with the rotating block. A suction cup is fixedly installed at the end, away from the rotating block, of the threaded short shaft, and a threaded hole is formed in the connecting plate. According to the utility model, not only is the sample plate conveniently clamped and positioned, but also the phenomenon of inaccurate detection caused by inclination of the sample plate can be avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of enzyme-labeled detection equipment, in particular to an enzyme-labeled instrument for laboratory use. Background Art

[0002] The microplate reader is a commonly used detection instrument in analytical biology for measuring the rate and activity of enzymatic reactions. It can determine the concentration or activity of a specific enzyme in a target sample by detecting parameters such as reaction depth, color change, and luminescence. Its working principle is to add the target sample to a reaction system containing a substrate, and use the specific catalytic effect of the enzyme to cause a specific reaction change in the substrate. Then, the activity level of the enzyme is determined by measuring the changes in optical signals generated by the reaction, such as absorbance, luminescence intensity, etc.

[0003] During use of existing laboratory ELISA instruments, the sample plate needs to be placed in a positioning groove and moved into the detector for detection. However, the inventors found that when the sample plate is placed in the positioning groove, the sample plate is prone to tilt, resulting in inaccurate detection. Therefore, we propose a laboratory ELISA instrument. Utility Model Content

[0004] 1. Technical issues to be solved

[0005] In view of the deficiencies in the prior art, the utility model provides a laboratory ELISA instrument, which has the advantages of conveniently snapping and positioning a sample plate to avoid inaccurate detection caused by tilting of the sample plate, thereby solving the problem of inaccurate detection caused by easy tilting of the sample plate.

[0006] (II) Technical solution

[0007] In order to achieve the above-mentioned purpose of conveniently snapping and positioning the sample plate to avoid the sample plate from tilting and causing inaccurate detection, the utility model provides the following technical solutions: a laboratory microplate reader, including an microplate reader, the outer surface of the microplate reader is provided with an anti-slip structure, a support plate is fixedly installed on the bottom wall of the inner cavity of the microplate reader, an opening and closing structure is provided on the support plate, a movable plate is provided on the opening and closing structure, and the sample plate is provided on the movable plate, and the movable plate is movably connected to the opening on the microplate reader to facilitate the snap-in positioning of the sample plate, thereby avoiding the sample plate from tilting and causing inaccurate detection.

[0008] As a preferred technical solution of the utility model, the anti-slip structure includes a connecting plate, which is fixedly connected to the outer surface of the microplate reader, and a threaded short shaft is arranged inside the connecting plate, and a rotating block is fixedly installed at one end of the threaded short shaft, and a suction cup is fixedly installed at the end of the threaded short shaft away from the rotating block. The microplate reader is placed on the laboratory table and then the block is spirally rotated. At this time, the rotating block drives the threaded short shaft to move in the inner cavity of the threaded hole and move toward the direction of the laboratory table. At the same time, the threaded short shaft drives the suction cup to move until the suction cup is adsorbed on the laboratory table to prevent the microplate reader from sliding, thereby facilitating the adsorption and fixation of the microplate reader to prevent the microplate reader from sliding.

[0009] As a preferred technical solution of the utility model, a threaded hole is opened inside the connecting plate, and the inner cavity of the threaded hole is threadedly connected to the outer surface of the threaded short shaft to facilitate the threaded movement of the threaded short shaft inside the connecting plate.

[0010] As a preferred technical solution of the utility model, a movable hole is opened inside the support plate, and the inner cavity of the movable hole is movably connected to the opening and closing structure to facilitate the rotation of the opening and closing structure;

[0011] A slide groove is provided on the inner side of the support plate, and the inner cavity of the slide groove is movably connected to the movable plate so that the movable plate can move along the inner cavity of the slide groove.

[0012] As a preferred technical solution of the utility model, the opening and closing structure includes a motor, the motor is fixedly connected to the support plate, and the output shaft on the motor is movably connected to the inner cavity of the movable hole;

[0013] A rotating rod is fixedly mounted on the output shaft of the motor, and the outer surface of the rotating rod is movably connected to the inner cavity of the movable hole, a gear is fixedly sleeved on the outer surface of the rotating rod, and a rack is meshingly connected to the outer surface of the gear, and the rack is fixedly connected to the bottom end of the movable plate. By starting the motor, the output shaft on the motor drives the rotating rod to rotate in the inner cavity of the movable hole, and the rotating rod drives the gear to rotate, the gear drives the rack to move, and the rack drives the movable plate to move. At the same time, the movable plate drives the slider to slide along the inner cavity of the slide groove until the sample plate on the movable plate is completely collected into the microplate reader, and then the microplate reader is used for detection, thereby facilitating the automatic storage of the sample plate, and then facilitating the automatic storage of the sample tube.

[0014] As a preferred technical solution of the utility model, sliders are fixedly installed on the outer surfaces of both sides of the movable plate, and the outer surfaces of the sliders are slidably connected to the inner cavity of the slide groove to facilitate the sliders to slide along the inner cavity of the slide groove.

[0015] As a preferred technical solution of the utility model, a snap-in groove is provided inside the top of the movable plate, and positioning holes are provided at the four corners of the inner cavity of the snap-in groove. The inner cavities of the snap-in groove and the positioning holes are movably connected to the sample plate to facilitate the assembly of the sample plate onto the movable plate in a snap-in and positioning manner.

[0016] As a preferred technical solution of the utility model, a sample hole is opened inside the top of the sample plate, and the sample holes are arranged in a rectangular linear array, and a taking hole is opened inside the top of the sample plate;

[0017] The outer surface of the sample plate is movably engaged with the inner cavity of the snap-fitting groove, and positioning posts are fixedly installed at the four corners of the sample plate. The outer surface of the positioning post is movably engaged with the inner cavity of the positioning hole. The sample plate with the sample tube is assembled onto the movable plate. At this time, the sample plate is snap-fitted to the inner cavity of the snap-fitting groove, and the positioning post is positioned and snap-fitted to the inner cavity of the positioning hole until the sample plate is assembled onto the movable plate in a snap-fitting and positioning manner, thereby facilitating the snap-fitting and positioning of the sample plate, thereby avoiding the phenomenon of inaccurate detection caused by the tilt of the sample plate.

[0018] (III) Beneficial effects

[0019] Compared with the prior art, the utility model provides a laboratory microplate reader, which has the following beneficial effects:

[0020] 1. The laboratory uses an ELISA instrument, which assembles a sample plate with sample tubes onto a movable plate. At this time, the sample plate is snapped into the inner cavity of the snap-fit ​​groove, and the positioning column is snapped into the inner cavity of the positioning hole until the sample plate is snap-fitted and positioned onto the movable plate, thereby facilitating the snap-fitting and positioning of the sample plate, thereby avoiding the phenomenon of inaccurate detection caused by the tilt of the sample plate.

[0021] 2. The laboratory uses an ELISA reader. The ELISA reader is placed on the laboratory table and then the spiral rotating block is driven by the rotating block to move the threaded short shaft in the inner cavity of the threaded hole and move toward the direction of the laboratory table. At the same time, the threaded short shaft drives the suction cup to move until the suction cup is adsorbed on the laboratory table to prevent the ELISA reader from sliding, thereby facilitating the adsorption and fixation of the ELISA reader to prevent the ELISA reader from sliding.

[0022] 3. The laboratory uses an ELISA instrument. By starting the motor, the output shaft on the motor drives the rotating rod to rotate in the inner cavity of the movable hole. At the same time, the rotating rod drives the gear to rotate, the gear drives the rack to move, and the rack drives the moving plate to move. At the same time, the moving plate drives the slider to slide along the inner cavity of the slide groove until the sample plate on the moving plate is completely collected in the ELISA instrument. Then the ELISA instrument is used for detection, so as to facilitate the automatic storage of the sample plate and the automatic storage of the sample tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a main stereoscopic view of the utility model;

[0024] Figure 2 It is a cutaway stereogram of the utility model;

[0025] Figure 3 This is a three-dimensional diagram of the connection between the support plate, the opening and closing structure and the movable plate of the utility model;

[0026] Figure 4 This is an exploded stereogram of the movable plate and the sample plate of the utility model.

[0027] In the figure: 1. ELISA instrument; 2. Anti-skid structure; 21. Connecting plate; 211. Threaded hole; 22. Threaded short shaft; 23. Rotating block; 24. Suction cup; 3. Support plate; 31. Movable hole; 32. Slide groove; 4. Opening and closing structure; 41. Motor; 42. Turning rod; 43. Gear; 44. Rack; 5. Moving plate; 51. Snap-in groove; 52. Positioning hole; 53. Sliding block; 6. Sample plate; 61. Sample hole; 62. Pick-up hole; 63. Positioning column. DETAILED DESCRIPTION

[0028] In order to make the above-mentioned purposes, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0029] Example 1

[0030] Reference Figure 1 and Figure 4 , which is the first embodiment of the utility model, provides a laboratory microplate reader, including a microplate reader 1, the outer surface of the microplate reader 1 is provided with an anti-slip structure 2, a support plate 3 is fixedly installed on the bottom wall of the inner cavity of the microplate reader 1, an opening and closing structure 4 is provided on the support plate 3, a movable plate 5 is provided on the opening and closing structure 4, a sample plate 6 is provided on the movable plate 5, and the movable plate 5 is movably connected to the opening on the microplate reader 1.

[0031] The anti-slip structure 2 includes a connecting plate 21, which is fixedly connected to the outer surface of the microplate reader 1. A threaded short shaft 22 is arranged inside the connecting plate 21, a rotating block 23 is fixedly installed at one end of the threaded short shaft 22, and a suction cup 24 is fixedly installed at the end of the threaded short shaft 22 away from the rotating block 23.

[0032] A threaded hole 211 is formed inside the connecting plate 21 , and an inner cavity of the threaded hole 211 is threadedly connected to an outer surface of the threaded short shaft 22 .

[0033] During use, the microplate reader 1 is placed on the laboratory table, and then the rotating block 23 is screwed on the threaded short shaft 22. At this time, the rotating block 23 drives the threaded short shaft 22 to move in the inner cavity of the threaded hole 211 and move toward the laboratory table. At the same time, the threaded short shaft 22 drives the suction cup 24 to move until the suction cup 24 is adsorbed on the laboratory table to prevent the microplate reader 1 from sliding, thereby facilitating the adsorption and fixation of the microplate reader 1 to prevent the microplate reader 1 from sliding.

[0034] Example 2

[0035] Reference Figure 1-4 , which is the second embodiment of the utility model. This embodiment is different from the first embodiment in that: a movable hole 31 is opened inside the support plate 3, and the inner cavity of the movable hole 31 is movably connected to the opening and closing structure 4;

[0036] A slide groove 32 is provided on the inner side of the support plate 3 , and the inner cavity of the slide groove 32 is movably connected to the movable plate 5 .

[0037] The opening and closing structure 4 includes a motor 41, the motor 41 is fixedly connected to the support plate 3, and the output shaft on the motor 41 is movably connected to the inner cavity of the movable hole 31;

[0038] A rotating rod 42 is fixedly mounted on the output shaft of the motor 41, and the outer surface of the rotating rod 42 is movably connected to the inner cavity of the movable hole 31. A gear 43 is fixedly sleeved on the outer surface of the rotating rod 42, and a rack 44 is meshingly connected to the outer surface of the gear 43. The rack 44 is fixedly connected to the bottom end of the movable plate 5.

[0039] Slide blocks 53 are fixedly mounted on both side outer surfaces of the movable plate 5 , and the outer surfaces of the slide blocks 53 are slidably connected to the inner cavity of the slide groove 32 .

[0040] A clamping groove 51 is provided inside the top of the movable plate 5 , and positioning holes 52 are provided at four corners of the inner cavity of the clamping groove 51 . The inner cavities of the clamping groove 51 and the positioning holes 52 are movably connected to the sample plate 6 .

[0041] A sample hole 61 is provided inside the top of the sample plate 6, and the sample holes 61 are arranged in a rectangular linear array. A taking hole 62 is provided inside the top of the sample plate 6;

[0042] The outer surface of the sample plate 6 is movably engaged with the inner cavity of the engaging groove 51 . Positioning posts 63 are fixedly installed at the four corners of the sample plate 6 . The outer surface of the positioning posts 63 is movably engaged with the inner cavity of the positioning hole 52 .

[0043] During use, the sample plate 6 with the sample tube is assembled onto the movable plate 5. At this time, the sample plate 6 is snapped into the inner cavity of the snap groove 51, and the positioning column 63 is snapped into the inner cavity of the positioning hole 52 until the sample plate 6 is assembled onto the movable plate 5 in a snap-fitting and positioning manner, thereby facilitating the snap-fitting and positioning of the sample plate 6, thereby avoiding the phenomenon of inaccurate detection caused by the tilt of the sample plate 6.

[0044] Then, by starting the motor 41 fixed on the support plate 3, the output shaft on the motor 41 drives the rotating rod 42 fixed on the output shaft to rotate in the inner cavity of the movable hole 31, and at the same time, the rotating rod 42 drives the gear 43 to rotate, the gear 43 drives the rack 44 to move, and the rack 44 drives the movable plate 5 to move. At the same time, the movable plate 5 drives the slider 53 to slide along the inner cavity of the slide groove 32 until the sample plate 6 on the movable plate 5 is completely received into the microplate reader 1, and then the microplate reader 1 is used for detection, so as to facilitate the automatic storage of the sample plate 6, and then facilitate the automatic storage of the sample tube.

[0045] The remaining structures are the same as those of Example 1.

[0046] It should be noted that the above embodiments are only used to illustrate the technical solution of the utility model rather than to limit it. Although the utility model has been described in detail with reference to the preferred embodiments, ordinary technicians in the field should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the spirit and scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.

Claims

1. A laboratory microplate reader, comprising a microplate reader (1), characterized in that: The outer surface of the microplate reader (1) is provided with an anti-slip structure (2); a support plate (3) is fixedly mounted on the bottom wall of the inner cavity of the microplate reader (1); an opening and closing structure (4) is provided on the support plate (3); a movable plate (5) is provided on the opening and closing structure (4); a sample plate (6) is provided on the movable plate (5); and the movable plate (5) is movably connected to an opening on the microplate reader (1).

2. A laboratory microplate reader according to claim 1, characterized in that: The anti-slip structure (2) comprises a connecting plate (21), the connecting plate (21) being fixedly connected to the outer surface of the microplate reader (1), a threaded short shaft (22) being arranged inside the connecting plate (21), a rotating block (23) being fixedly mounted on one end of the threaded short shaft (22), and a suction cup (24) being fixedly mounted on one end of the threaded short shaft (22) away from the rotating block (23).

3. A laboratory microplate reader according to claim 2, characterized in that: A threaded hole (211) is provided inside the connection plate (21), and an inner cavity of the threaded hole (211) is threadedly connected to an outer surface of the threaded short shaft (22).

4. A laboratory microplate reader according to claim 1, characterized in that: A movable hole (31) is provided inside the support plate (3), and the inner cavity of the movable hole (31) is movably connected to the opening and closing structure (4); A sliding groove (32) is provided on the inner side of the support plate (3), and the inner cavity of the sliding groove (32) is movably connected to the movable plate (5).

5. A laboratory microplate reader according to claim 4, characterized in that: The opening and closing structure (4) comprises a motor (41), the motor (41) is fixedly connected to the support plate (3), and the output shaft on the motor (41) is movably connected to the inner cavity of the movable hole (31); A rotating rod (42) is fixedly mounted on the output shaft of the motor (41); the outer surface of the rotating rod (42) is movably connected to the inner cavity of the movable hole (31); a gear (43) is fixedly sleeved on the outer surface of the rotating rod (42); a rack (44) is meshingly connected to the outer surface of the gear (43); and the rack (44) is fixedly connected to the bottom end of the movable plate (5).

6. A laboratory microplate reader according to claim 5, characterized in that: Slide blocks (53) are fixedly mounted on the outer surfaces of both sides of the movable plate (5), and the outer surfaces of the slide blocks (53) are slidably connected to the inner cavity of the slide groove (32).

7. A laboratory microplate reader according to claim 5, characterized in that: A snap-fit ​​groove (51) is provided inside the top end of the movable plate (5), and positioning holes (52) are provided at four corners of the inner cavity of the snap-fit ​​groove (51). The inner cavities of the snap-fit ​​groove (51) and the positioning holes (52) are movably connected to the sample plate (6).

8. A laboratory microplate reader according to claim 7, characterized in that: A sample hole (61) is provided inside the top of the sample plate (6), and the sample holes (61) are arranged in a rectangular linear array. A taking hole (62) is provided inside the top of the sample plate (6); The outer surface of the sample plate (6) is movably engaged with the inner cavity of the engaging groove (51); positioning columns (63) are fixedly installed at the four corners of the sample plate (6); and the outer surface of the positioning column (63) is movably engaged with the inner cavity of the positioning hole (52).