Powder-liquid double-chamber bag production system

Abstract

The utility model relates to the technical field of sterile medicine production, and discloses a powder-liquid double-chamber bag production system which comprises a powder production system and a powder-liquid double-chamber combined production system, the powder production system comprises a powder raw material chamber, a powder mixing chamber and a powder temporary storage chamber, and the powder-liquid double-chamber combined production system comprises a powder subpackaging chamber. The powder mixing chamber is used for achieving mixing of multi-component powder, the multi-component mixed powder is conveyed to the powder temporary storage chamber in the powder production system according to the sequence of the powder raw material chamber and the powder mixing chamber, single-component powder is directly conveyed to the powder temporary storage chamber after passing through the powder raw material chamber, and the powder temporary storage chamber provides powder for the powder subpackaging chamber. According to the utility model, by adding and integrating related production links and re-planning the environmental area of each production link according to the requirements on the product quality, the production system is further improved, the whole process flow is optimized, the sterile production, the guarantee of the internal quality of medicines and the control of foreign matters are more facilitated, and meanwhile, the energy consumption and the production cost are reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of sterile medicine production, in particular to a powder-liquid double-chamber bag production system. Background Art

[0002] Powder-liquid dual-chamber bag infusion medicine is a combination packaged medicine that contains both liquid and powder dosage forms. Its characteristic is that the liquid and powder medicines are filled in the two chambers of the same non-PVC infusion bag respectively, forming a whole, which is convenient for clinical use and improves drug safety. Its production process includes two major parts: non-PVC soft bag liquid filling and powder packaging.

[0003] The production of non-PVC soft bags (liquids) and the packaging of powders in vials both have mature production systems and processes. Different processes have different requirements for the environment. For example, the liquid preparation process needs to be carried out in a Class C clean area, the bag making and filling process needs to be carried out in a Class C+A clean area, and the production auxiliary process needs to be carried out in a clean area of ​​the same clean level as the assisted process. Other processes can be set up in the ordinary production area.

[0004] Due to the particularity of powder-liquid double-chamber bag products, its production process is not a simple superposition of two dosage forms of drug production systems. The key lies in how to reasonably arrange the entire production system based on the particularity of the double-chamber bag product itself, the process requirements of the two dosage forms and the requirements for environmental cleanliness, so as to organically combine the production processes of the two dosage forms, improve space utilization, reduce energy consumption and production costs, and ensure efficient operation of the entire production system.

[0005] The applicant has applied for a Chinese patent "A Powder-Liquid Dual Chamber Bag Production System" with authorization announcement number CN203958732U for the above-mentioned problem. The application rationally arranges the entire production system according to the process requirements in liquid production and powder production, realizes the organic combination of the two dosage form production processes, and forms a new production system including liquid and powder production. During long-term use, the applicant discovered that the above-mentioned production system did not integrate the production links of powder entry and multi-component powder mixing preparation; there was no powder chamber aluminum film coating quality inspection link, resulting in the inability to timely discover aluminum film sealing defects, affecting the intrinsic quality of the product; and, the powder chamber light inspection link, powder chamber aluminum film coating link, and packaging link in the above-mentioned production system are all set in the ordinary production area, which is not conducive to the control of packaging foreign matter and affects the product appearance quality. Therefore, it is necessary to further optimize and improve the existing powder-liquid dual chamber bag production system. Utility Model Content

[0006] In view of the problems existing in the prior art: the existing powder-liquid double-chamber bag production system has not integrated all production links. The purpose of the utility model is to provide a powder-liquid double-chamber bag production system, by adding and integrating relevant production links, and re-planning the environmental areas of each production link according to the demand for product quality, further improving the production system, optimizing the entire process flow, and being more conducive to aseptic production, intrinsic quality assurance of drugs, and foreign matter control, while reducing energy consumption and lowering production costs.

[0007] In order to achieve the above object, the technical solution of the utility model is:

[0008] A powder-liquid double chamber bag production system comprises a powder production system and a powder-liquid double chamber combined production system, wherein the powder production system comprises a powder raw material chamber, the powder-liquid double chamber combined production system comprises a powder filling chamber, the powder production system further comprises a powder mixing chamber and a powder temporary storage chamber, the powder mixing chamber is used to achieve mixing of multi-component powders, the multi-component mixed powders are conveyed to the powder temporary storage chamber in the order of the powder raw material chamber and the powder mixing chamber in the powder production system, and the single-component powders are directly conveyed to the powder temporary storage chamber after passing through the powder raw material chamber, the powder temporary storage chamber provides powder to the powder filling chamber, thereby providing a preparation link for the powders to enter the powder-liquid double chamber combined production system from the powder production system.

[0009] The utility model is further configured as follows: the powder raw material room, the powder mixing room, and the powder temporary storage room are all arranged in a B+A class clean area.

[0010] The utility model is further configured as follows: the powder production system also includes a second auxiliary function room, the second auxiliary function room is used to assist the powder production system, a plurality of second auxiliary function rooms are arranged in the second auxiliary function room, and the plurality of second auxiliary function rooms are respectively arranged in the Class B clean area and the Class B+A clean area.

[0011] The utility model is further configured as follows: the powder-liquid dual-chamber combined production system also includes a liquid cavity detection chamber, in which liquid cavity leakage detection and bad bag rejection equipment are arranged, and the liquid cavity detection chamber is arranged in a Class C clean area.

[0012] The utility model is further configured as follows: the powder-liquid dual-chamber combined production system also includes a raw material temporary storage room, a liquid preparation room, a bag making and filling room, and a sterilization preparation room. The raw material temporary storage room, the bag making and filling room, and the sterilization preparation room are all arranged in a Class C clean area, and the liquid preparation room is arranged in a CNC control area.

[0013] The utility model is further configured such that: the liquid enters the liquid cavity detection chamber directly after passing through the bag making and filling chamber, and enters the sterilization preparation chamber after being detected in the liquid cavity detection chamber.

[0014] The utility model is further configured as follows: the powder-liquid dual-chamber combined production system also includes a first auxiliary function room, the first auxiliary function room is used to assist the powder-liquid dual-chamber combined production system, and the first auxiliary function room is arranged in a Class C clean area.

[0015] The utility model is further configured as follows: the powder-liquid dual-chamber combined production system comprises a sterilization receiving chamber, and the powder filling chamber and the sterilization receiving chamber are both arranged in a B+A grade clean area.

[0016] The utility model is further configured as follows: the powder-liquid dual-chamber combined production system also includes an aluminum film packaging chamber and a leak detection chamber. The powder-liquid dual-chamber bag directly enters the leak detection chamber after completing the aluminum film sealing in the aluminum film packaging chamber. The leak detection chamber is used to detect the sealing performance of the powder-liquid dual-chamber bag after the aluminum film sealing.

[0017] The utility model is further configured as follows: the powder-liquid dual-chamber combined production system also includes a powder cavity detection chamber and an outer packaging chamber, and the powder cavity detection chamber, aluminum film packaging chamber, leak detection chamber and outer packaging chamber are all arranged in a CNC control area.

[0018] In summary, the beneficial effects achieved by the present invention are as follows:

[0019] (1) A powder mixing chamber for mixing multi-component powders and a powder temporary storage chamber for preparing the powder for entering the powder-liquid dual-chamber combined production system from the powder production system were added to the powder production system. The two were integrated into the entire powder-liquid dual-chamber bag production system and placed in a Class B+A clean area, thereby improving the entire powder-liquid dual-chamber bag production system.

[0020] (2) The liquid cavity detection chamber is provided with liquid cavity leak detection and bad bag rejection equipment. Since the liquid cavity leak detection and bad bag rejection equipment may cause pollution to the clean area of ​​the corresponding clean level during operation, compared with the prior art, the present application sets the liquid cavity detection chamber in a Class C clean area with a lower clean level rather than a Class B clean area, and moves the liquid cavity detection chamber forward to the rear of the bag making and filling chamber, so that in the powder-liquid dual-chamber combined production system, the infusion bag directly enters the liquid cavity detection chamber for leak detection after passing through the bag making and filling chamber. During the leak detection process, since the liquid cavity detection chamber, the bag making and filling chamber, and the sterilization preparation room behind the liquid cavity detection chamber are all set in the Class C clean area, the pollution of the higher-level clean area by the liquid cavity detection chamber in the prior art is avoided, which is more conducive to the control of aseptic production and also helps to reduce the energy consumption for maintaining a higher-level clean area;

[0021] (3) A new leak detection chamber is added to the powder-liquid dual-chamber combined production system for testing the sealing performance of the powder-liquid dual-chamber bag after it is sealed with aluminum film. The leak detection chamber is located behind the aluminum film packaging chamber, so that the powder-liquid dual-chamber bag can directly enter the leak detection chamber after the aluminum film is sealed in the aluminum film packaging chamber, thereby promptly discovering infusion bags with defective aluminum film sealing to prevent them from affecting the intrinsic quality of the product;

[0022] (4) Compared with the prior art, the present application sets the powder chamber detection chamber, aluminum film packaging chamber, outer packaging chamber and the newly added leak detection chamber in the powder-liquid dual-chamber combined production system in the CNC control area rather than the ordinary production area, which is beneficial to control foreign matter in the packaging process and prevent it from affecting the appearance and quality of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the specification will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0024] Figure 1 This is the process block diagram of the medium powder-liquid double chamber bag production system of the utility model;

[0025] Figure 2 This is a plan layout diagram of the powder-liquid double-chamber bag production system of the utility model.

[0026] In the figure: 101, raw material temporary storage room; 102, liquid preparation room; 103, bag making and filling room; 104, liquid cavity detection room; 105, sterilization preparation room; 106, sterilization dryer; 107, sterilization receiving room; 108, first auxiliary function room; 109, powder filling room; 110, powder cavity detection room; 111, aluminum film packaging room; 112, leak detection room; 113, outer packaging room; 201, powder raw material room; 202, powder mixing room; 203, powder temporary storage room; 204, second auxiliary function room. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present invention are described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. For ease of explanation, the terms "vertical", "horizontal", "left", "right", "upper", "lower", "inner", "outer", "bottom", etc. used in this specification indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as a limitation on the present application.

[0028] It should be noted that the embodiments of the present invention and the features involved in the embodiments can be combined with each other without conflict. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.

[0029] As attached Figure 1-2 As shown, a powder-liquid dual-chamber bag production system includes an integrated powder production system and a powder-liquid dual-chamber combined production system.

[0030] The powder-liquid dual-chamber combined production system comprises a raw material temporary storage chamber 101 , a liquid preparation chamber 102 , a bag making and filling chamber 103 and a liquid cavity detection chamber 104 .

[0031] The raw material temporary storage room 101 contains liquid medicines and inner packaging materials. The liquid medicines enter the liquid preparation room 102, and enter the bag making and filling chamber 103 after the liquid preparation process is completed by the liquid preparation equipment in the liquid preparation room 102; the inner packaging materials in the raw material temporary storage room 101 directly enter the bag making and filling chamber 103, and are filled and sealed with the liquid medicines that have completed the liquid preparation through the bag making and filling machine in the bag making and filling chamber 103.

[0032] After passing through the bag making and filling chamber 103, the infusion bag directly enters the liquid cavity inspection chamber 104 for inspection. The liquid cavity inspection chamber 104 is equipped with a liquid cavity light inspection machine, a liquid cavity leak detection and bad bag rejection equipment, which can inspect the bag body of the infusion bag and promptly reject unqualified infusion bags such as sealing leakage and bag body damage to prevent them from flowing into the next process.

[0033] In terms of clean level settings, the raw material temporary storage room 101, the bag making and filling room 103 and the liquid cavity detection room 104 are all arranged in the Class C clean area, while the liquid preparation room 102 is arranged in the CNC control area.

[0034] The classification of clean area levels involved in this utility model uses the current pharmaceutical production management specifications. Clean areas are divided according to indicators such as air cleanliness, air pressure, air volume, temperature and humidity, noise, and microbial content, and are divided into four levels: A, B, C, and D. Among them, the A-level clean area is the cleanest clean area, and the D-level clean area is the lowest clean area. The C+A and B+A levels refer to the air cleanliness levels defined in the International Organization for Standardization 14644-1 standard. The cleanliness of the C+A level is ISO 7 (i.e. 1m 3 The cleanliness level of B+A is ISO 5 (i.e. 1m 3In order to achieve high-level cleanliness requirements, high-efficiency filters, differential pressure control, air circulation systems, and constant temperature and humidity control systems are required to achieve high cleanliness requirements. Therefore, the higher the cleanliness, the more energy is consumed to maintain the clean area, and the higher the cost.

[0035] CNC area refers to a controlled but non-clean area, which is controlled but not divided into specific area levels. Compared with the traditional clean area, there is no need to set relevant dust particle limits or monitor, but relevant cleaning and control are required.

[0036] The powder-liquid dual-chamber combined production system also includes a sterilization preparation chamber 105 , a sterilization dryer 106 and a sterilization receiving chamber 107 .

[0037] The qualified infusion bag after passing through the liquid cavity detection chamber 104 enters the sterilization preparation chamber 105. The sterilization preparation chamber 105 is provided with a bag sterilization preparation device, which transfers the infusion bag to the sterilization dryer 106.

[0038] The sterilization dryer 106 is used to sterilize and dry the infusion bag. The sterilization dryer 106 itself does not need to be provided with a clean area, but its cabinet chamber is a high cleanliness environment. The infusion bag dried by the sterilization dryer 106 enters the sterilization receiving chamber 107. The sterilization receiving chamber 107 is provided with a sterilized cool bag unloading device, which is used to receive the infusion bag that has passed through the sterilization dryer 106.

[0039] In the above process, the sterilization preparation room 105 is set in the C-class clean area, and the sterilization receiving room 107 is set in the B+A-class clean area.

[0040] The powder-liquid dual-chamber combined production system further includes a first auxiliary function room 108, in which a plurality of first auxiliary function rooms are arranged, and all the first auxiliary function rooms are arranged in a Class C clean area. The first auxiliary function room 108 is used to assist the powder-liquid dual-chamber combined production system.

[0041] The powder production system includes a powder raw material room 201 , a powder mixing room 202 and a powder temporary storage room 203 .

[0042] A powder raw material sterilizer is provided in the powder raw material chamber 201, which is used to sterilize the powder raw materials and their packaging. After the multi-component powders in the powder raw material chamber 201 enter the powder mixing chamber 202, a powder mixer and a primary filling machine are provided in the powder mixing chamber 202. The powder mixer is used to mix the multi-component powders, and after mixing, the powders are filled by the primary filling machine and then enter the powder temporary storage chamber 203 for storage and standby. When the powder type used in the produced medicine is single and does not require the mixing of multi-component powders, the single-component powder in the powder raw material chamber 201 can directly enter the powder temporary storage chamber 203. The powder temporary storage chamber 203 provides a preparation process for the powder to enter the powder-liquid dual-chamber combined production system from the powder production system.

[0043] In the above process, the powder raw material room 201, the powder mixing room 202, and the powder temporary storage room 203 are all arranged in a B+A class clean area.

[0044] The powder production system also includes a second auxiliary function room 204, which is used to assist the powder production system. The second auxiliary function room 204 is provided with a plurality of second auxiliary function rooms, and different second auxiliary function rooms are used to assist different process links. Due to different requirements for process parameters, the plurality of second auxiliary function rooms are respectively provided in the Class B clean area and the Class B+A clean area.

[0045] The powder-liquid dual-chamber combined production system also includes a powder filling chamber 109 , a powder cavity detection chamber 110 , an aluminum film packaging chamber 111 , a leak detection chamber 112 and an outer packaging chamber 113 .

[0046] The powder filling chamber 109 is provided with a powder filling machine and a bag sealing machine, so it has a high requirement for cleanliness and needs to be set in a Class B+A clean area. The powder temporary storage chamber 203 provides single-component powder or multi-component powder to the powder filling chamber 109, thereby providing a preparation link for the powder to enter the powder-liquid dual-chamber combined production system from the powder production system.

[0047] After the powder-liquid double chamber bag is sealed in the powder dispensing chamber 109, it first enters the powder cavity detection chamber 110 for detection. A powder cavity light inspection machine is provided in the powder cavity detection chamber 110, and only qualified powder-liquid double chamber bags can enter the aluminum film packaging chamber 111 after being inspected.

[0048] An aluminum film coating machine is provided in the aluminum film packaging room 111. After the powder-liquid double chamber bag is sealed by aluminum film coating in the aluminum film packaging room 111, it directly enters the leak detection room 112. An aluminum film sealing leak detection machine is provided in the leak detection room 112 to detect the sealing of the powder-liquid double chamber bag after aluminum film coating. The powder-liquid double chamber bag products with good sealing quality finally enter the outer packaging room 113, and the packaging equipment in the outer packaging room 113 packages the powder-liquid double chamber bag products with outer packaging materials.

[0049] In the above process, the powder chamber detection chamber 110, the aluminum film packaging chamber 111, the leak detection chamber 112 and the outer packaging chamber 113 are all arranged in the CNC control area.

[0050] It should be noted that the equipment used in each process of the powder-liquid double chamber bag production system in the present invention are all mature production equipment in the prior art, so no further description of such equipment is given. In addition, this application focuses on the setting of each production process, the sequence and location of the process, and the clean area level of the equipment used in each process. Other process requirements and related equipment required in the powder-liquid double chamber bag production system in this application belong to the prior art, so no further description is given.

[0051] The implementation principle of the above embodiment is:

[0052] The liquid medicine in the temporary raw material storage room 101 passes through the liquid preparation room 102 and enters the bag filling and sealing room 103. After the filling and sealing, the infusion bag directly enters the liquid cavity detection room 104 for detection. After the unqualified infusion bags are removed, they enter the sterilization preparation room 105. The infusion bags in the sterilization preparation room 105 pass through the sterilization dryer 106 and enter the sterilization receiving room 107.

[0053] The powder in the powder raw material chamber 201 determines whether it needs to pass through the powder mixing chamber 202 according to the type of the powder. Multi-component powders that need to be mixed first enter the powder mixing chamber 202 and then enter the powder temporary storage chamber 203, while single-component powders that do not need to be mixed directly enter the powder temporary storage chamber 203.

[0054] The powder in the powder temporary storage room 203 and the infusion bag in the sterilization receiving room 107 enter the powder filling room 109 for filling and sealing. After the sealing is completed, they first enter the powder cavity detection room 110 for detection. Only qualified powder-liquid double-chamber bag products can enter the aluminum film packaging room 111. After the aluminum film is sealed in the aluminum film packaging room 111, they enter the leak detection room 112. The sealed and qualified powder-liquid double-chamber bag products finally enter the outer packaging room 113 for packaging.

[0055] Compared with the prior art, the powder-liquid dual-chamber bag production system in the present application has a newly added powder mixing chamber 202 for achieving multi-component powder mixing and a powder temporary storage chamber 203 that can provide a preparation process for the powder to enter the powder-liquid dual-chamber combined production system from the powder production system, and a newly added leak detection chamber 112 for detecting the sealing of the powder-liquid dual-chamber bag after the aluminum film is sealed, and the powder mixing chamber 202, the powder temporary storage chamber 203 and the leak detection chamber 112 are integrated into the entire powder-liquid dual-chamber bag production system, thereby improving the powder-liquid dual-chamber bag production system. In addition, the present application moves the liquid cavity detection chamber 104 forward to the rear of the bag-making and filling chamber 103, so that the infusion bag directly enters the liquid cavity detection chamber 104 for leak detection after passing through the bag-making and filling chamber 103, and the powder-liquid dual-chamber bag can also directly enter the leak detection chamber 112 after completing the aluminum film sealing, so that defective products can be discovered in time and product quality can be improved. Finally, by replanning the clean areas where each production link is located, it is beneficial to the control of aseptic production, and it is also beneficial to reduce the energy consumption for maintaining clean areas and reduce production costs.

[0056] Although preferred embodiments of the present invention have been described, those skilled in the art may make additional changes and modifications to these embodiments once they are aware of the basic creative concepts. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the present invention. Obviously, those skilled in the art may make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A powder-liquid dual-chamber bag production system, comprising a powder production system and a powder-liquid dual-chamber combined production system, wherein the powder production system comprises a powder raw material chamber (201), and the powder-liquid dual-chamber combined production system comprises a powder filling chamber (109), characterized in that: The powder production system further comprises a powder mixing chamber (202) and a powder temporary storage chamber (203). The powder mixing chamber (202) is used to achieve mixing of multi-component powders. In the powder production system, the multi-component mixed powders are transferred to the powder temporary storage chamber (203) in the order of the powder raw material chamber (201) and the powder mixing chamber (202), while the single-component powders are directly transferred to the powder temporary storage chamber (203) after passing through the powder raw material chamber (201). The powder temporary storage chamber (203) provides powders to the powder filling chamber (109), thereby providing a preparation link for the powders to enter the powder-liquid dual-chamber combined production system from the powder production system.

2. The powder-liquid double chamber bag production system according to claim 1, characterized in that: The powder raw material room (201), the powder mixing room (202), and the powder temporary storage room (203) are all arranged in a Class B+A clean area.

3. The powder-liquid double chamber bag production system according to claim 2, characterized in that: The powder production system further comprises a second auxiliary function room (204), wherein the second auxiliary function room (204) is used to assist the powder production system, and a plurality of second auxiliary function rooms are arranged in the second auxiliary function room (204), and the plurality of second auxiliary function rooms are respectively arranged in a Class B clean area and a Class B+A clean area.

4. The powder-liquid double chamber bag production system according to claim 1, characterized in that: The powder-liquid dual-chamber combined production system further comprises a liquid cavity detection chamber (104), wherein a liquid cavity leakage detection and bad bag rejection device is arranged in the liquid cavity detection chamber (104), and the liquid cavity detection chamber (104) is arranged in a Class C clean area.

5. The powder-liquid double chamber bag production system according to claim 4, characterized in that: The powder-liquid dual-chamber combined production system further comprises a raw material temporary storage room (101), a liquid preparation room (102), a bag making and filling room (103) and a sterilization preparation room (105); the raw material temporary storage room (101), the bag making and filling room (103) and the sterilization preparation room (105) are all arranged in a Class C clean area, and the liquid preparation room (102) is arranged in a CNC control area.

6. The powder-liquid double chamber bag production system according to claim 5, characterized in that: The liquid enters the liquid cavity detection chamber (104) directly after passing through the bag making and filling chamber (103), and enters the sterilization preparation chamber (105) after being detected in the liquid cavity detection chamber (104).

7. The powder-liquid double chamber bag production system according to claim 5, characterized in that: The powder-liquid dual-chamber combined production system further comprises a first auxiliary function room (108), wherein the first auxiliary function room (108) is used to assist the powder-liquid dual-chamber combined production system, and the first auxiliary function room (108) is arranged in a Class C clean area.

8. The powder-liquid double chamber bag production system according to claim 1, characterized in that: The powder-liquid dual-chamber combined production system further comprises a sterilization receiving chamber (107), and the powder filling chamber (109) and the sterilization receiving chamber (107) are both arranged in a B+A grade clean area.

9. The powder-liquid double chamber bag production system according to claim 1, characterized in that: The powder-liquid dual-chamber combined production system further comprises an aluminum film packaging chamber (111) and a leak detection chamber (112); the powder-liquid dual-chamber bag directly enters the leak detection chamber (112) after completing the aluminum film sealing in the aluminum film packaging chamber (111); the leak detection chamber (112) is used to detect the sealing performance of the powder-liquid dual-chamber bag after the aluminum film sealing.

10. The powder-liquid double chamber bag production system according to claim 9, characterized in that: The powder-liquid dual-chamber combined production system further comprises a powder chamber detection chamber (110) and an outer packaging chamber (113); the powder chamber detection chamber (110), the aluminum film packaging chamber (111), the leak detection chamber (112) and the outer packaging chamber (113) are all arranged in a CNC control area.

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