PCR (Polymerase Chain Reaction) gene amplification instrument convenient to maintain

Abstract

The utility model discloses a PCR (Polymerase Chain Reaction) gene amplification instrument convenient to maintain, which comprises a gene amplification instrument main body and a cover body, a sample groove is arranged in the middle of one side of the top of the gene amplification instrument main body, and a hot cover matched with the sample groove is arranged on one side of the top of the gene amplification instrument main body. A spring A is arranged on the other side of the top of the gene amplification instrument main body, and a heat dissipation plate is arranged at the bottom of the sample groove; according to the gene amplification instrument, the fan, the cover body, the elastic sheet, the electric contact block and the mounting plate are matched with one another, so that the fan is mounted on the cover body, the fan can be directly dismounted to be overhauled and cleaned conveniently when the device is maintained, the elastic sheet can be automatically contacted with the electric contact block to be electrified after the cover body is closed, the fan and the gene amplification instrument main body are mounted in a split manner, and the mounting efficiency is improved. The installation space in the gene amplification instrument main body is saved, so that internal parts are more intuitive during maintenance and overhaul, the operation space is enlarged, and the maintenance convenience is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of PCR gene amplification instruments, in particular to a PCR gene amplification instrument which is easy to maintain. Background Art

[0002] Polymerase chain reaction, abbreviated as PCR, is a method of in vitro enzymatic synthesis of specific DNA fragments. It consists of a cycle of high-temperature denaturation, low-temperature annealing and temperature-appropriate extension. The cycle allows the target DNA to be rapidly amplified. It has the characteristics of strong specificity, high sensitivity, simple operation and time saving. It can not only be used for basic research such as gene isolation, cloning and nucleic acid sequence analysis, but also for disease diagnosis or any place with DNA and RNA. Polymerase chain reaction is also called cell-free molecular cloning or specific DNA sequence in vitro primer-directed enzymatic amplification technology;

[0003] The existing patent with the authorization announcement number "CN215856128U" discloses a gene amplification instrument, which sets the heating temperature of the heating chamber and the constant temperature time through the control panel to evenly heat the genes inside multiple test tubes. After heating, two cooling fans are operated at the same time to form convection in the internal air of the shell, so that the air flow is increased to achieve the purpose of heat dissipation. Multiple supporting feet can be extended and retracted inside the threaded groove. When the air inlet volume is too small, the height of the air inlet is adjusted through the multiple supporting feet, so that the air inlet volume further improves the cooling effect of the equipment, which is conducive to rapid heat dissipation and convenient for the use of the equipment.

[0004] However, there are the following deficiencies in this device:

[0005] 1. The cooling fan in the above device is installed in the main body of the device, which occupies a large amount of space in the device. When maintaining the equipment, it not only affects the operating space of the maintenance personnel, but also makes it inconvenient to disassemble and repair the cooling fan, reducing the convenience of maintenance;

[0006] 2. When the device is maintained, it is not convenient to disassemble and assemble the shell, which results in a long maintenance time and reduces the maintenance efficiency of the device. Utility Model Content

[0007] The utility model aims to provide a PCR gene amplification instrument which is easy to maintain, so as to solve the existing problems raised in the above-mentioned background technology.

[0008] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a PCR gene amplification instrument that is easy to maintain, comprising a gene amplification instrument body and a cover body, a sample slot is arranged in the middle of one side of the top of the gene amplification instrument body, a heat cover matched with the sample slot is arranged on one side of the top of the gene amplification instrument body, a spring A is arranged on the other side of the top of the gene amplification instrument body, a heat sink is arranged at the bottom of the sample slot, the bottom of the heat sink extends to the inside of the gene amplification instrument body, and a circuit board is arranged on one side of the inside of the gene amplification instrument body;

[0009] A fan is arranged on the inner side of the cover body, a spring is arranged on one side of the fan, a mounting plate is arranged in the middle of one side of one end of the main body of the gene amplification instrument, and an electric contact block matching with the spring is arranged in the middle of one side of the mounting plate;

[0010] A slot is provided on one side of the top and bottom of the cover body, a guide hole is provided on one side of the top and bottom of the inner side of the main body of the gene amplification instrument, wedge-shaped rods matching the slots are slidably inserted into the inner sides of two groups of the guide holes, springs B are provided at the top and bottom of the two groups of wedge-shaped rods away from each other, adjustment slots are provided on the top and bottom of the cover body, push rods are sleeved on the inner sides of the two groups of the slots, pull rods are sleeved on one side of the inside of the two groups of the adjustment slots, and push blocks matching the adjustment slots are provided on the side of the two groups of pull rods away from the top and bottom.

[0011] Preferably, handles are provided at the top and bottom of one side of the cover body to facilitate taking the cover body when removing it.

[0012] Preferably, a stopper is provided in the middle of the outer sides of the two groups of pull rods to limit the range of movement of the pull rods.

[0013] Preferably, a pull ring is provided on one side of the two groups of pull rods, and the pull ring is located on the inner side of the handle, so that the pull rods can be pulled conveniently through the pull ring.

[0014] Preferably, ventilation holes are provided in the middle of both ends of the main body of the gene amplification instrument to allow air flow to circulate in the main body of the gene amplification instrument.

[0015] Preferably, pressure blocks are provided at the top and bottom portions of the two groups of push rods which are far away from each other, and the wedge-shaped inserting rod can be pushed by the pressure blocks to pull the wedge-shaped inserting rod out of the slot.

[0016] Compared with the prior art, the utility model has the following beneficial effects: the PCR gene amplification instrument is easy to maintain;

[0017] 1. Through the cooperation between the fan, cover, spring, electric contact block and mounting plate, the device installs the fan on the cover, which is convenient for directly removing the fan for inspection and cleaning when maintaining the device. After the cover is closed, the spring can automatically contact the electric contact block to energize. By installing the fan and the main body of the gene thermal cycler separately, the installation space in the main body of the gene thermal cycler is saved, making the internal components more intuitive during maintenance and inspection, increasing the operating space and improving the convenience of maintenance;

[0018] 2. Through the cooperation between the pull rod, the adjustment slot, the push rod, the push block, the slot, the wedge-shaped rod, the guide hole and the spring B, when the device is in use, the pull rod can be pulled through the pull ring to quickly release the cover body and open the cover body. The disassembly is very convenient, which facilitates the maintenance of the main body of the gene thermal cycler. After the maintenance is completed, the cover body can be quickly fixed by inserting it into the main body of the gene thermal cycler, thereby improving the maintenance efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a three-dimensional diagram of the utility model;

[0020] Figure 2 It is a front cross-sectional view of the utility model;

[0021] Figure 3 For the utility model Figure 2 A schematic diagram of the structure at A;

[0022] Figure 4 For the utility model Figure 2 Enlarged schematic diagram of the structure at B.

[0023] In the figure: 1. Gene amplification instrument body; 2. Circuit board; 3. Heat sink; 4. Heat cover; 5. Sample slot; 6. Fan; 7. Cover; 8. Shrapnel; 9. Electric contact block; 10. Mounting plate; 11. Pull rod; 12. Spring A; 13. Adjustment slot; 14. Push rod; 15. Push block; 16. Slot; 17. Wedge-shaped rod; 18. Guide hole; 19. Spring B. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] See also Figure 1-4, the utility model provides an embodiment: a PCR gene amplification instrument that is easy to maintain, including a gene amplification instrument body 1 and a cover body 7, the top and bottom of one side of the cover body 7 are provided with handles, which are convenient for taking the cover body 7 when removing it, and the middle parts of the two ends of the inside of the gene amplification instrument body 1 are provided with vents, which can allow airflow to circulate in the gene amplification instrument body 1, and the middle part of one side of the top of the gene amplification instrument body 1 is provided with a sample slot 5, and one side of the top of the gene amplification instrument body 1 is provided with a heat cover 4 that matches the sample slot 5, and the other side of the top of the gene amplification instrument body 1 is provided with a spring A12, and the bottom of the sample slot 5 is provided with a heat sink 3, and the bottom of the heat sink 3 extends to the inside of the gene amplification instrument body 1, and one side of the inside of the gene amplification instrument body 1 is provided with a circuit board 2;

[0026] A fan 6 is arranged on the inner side of the cover 7, a spring piece 8 is arranged on one side of the fan 6, a mounting plate 10 is arranged in the middle of one side of one end of the main body 1 of the gene amplification instrument, and an electric contact block 9 matching with the spring piece 8 is arranged in the middle of one side of the mounting plate 10;

[0027] A slot 16 is provided on one side of the top and bottom of the cover body 7, a guide hole 18 is provided on one side of the top and bottom of the inner side of the main body 1 of the gene amplification instrument, wedge-shaped rods 17 matching the slot 16 are slidably inserted into the inner sides of the two groups of guide holes 18, and springs B19 are provided at the top and bottom of the two groups of wedge-shaped rods 17 away from each other. Adjustment grooves 13 are provided on the top and bottom of the cover body 7, push rods 14 are sleeved on the inner sides of the two groups of slots 16, and pull rods 11 are sleeved on one side of the two groups of adjustment grooves 13. Push blocks 15 matching the adjustment grooves 13 are provided on the side of the two groups of pull rods 11 away from the top and bottom.

[0028] Furthermore, a stopper is provided in the middle of the outer sides of the two groups of pull rods 11, so that when the pull rods 11 are pulled, the pull rods 11 can be limited by the stopper and can only move within a specified range, so that the push block 15 will not go over the push rod 14.

[0029] Furthermore, a pull ring is provided on one side of the two groups of pull rods 11, and the pull ring is located on the inner side of the handle. When the cover body 7 is disassembled, the handle can be held, and then the pull ring can be pulled with one finger to drive the two groups of pull rods 11 to move.

[0030] Furthermore, pressure blocks are provided at the top and bottom of the two groups of push rods 14 which are far away from each other, and the wedge-shaped inserting rod 17 can be pushed by the pressure blocks to pull the wedge-shaped inserting rod 17 out of the slot 16 .

[0031] Working principle: When the device is used, the gene sample can be placed in the sample slot 5, and the heat cover 4 is covered to heat and perform gene amplification. The sample data can be observed through the spring A12. When the device is used, the heat of the sample slot 5 can be absorbed by the heat sink 3 to cool it, and then the fan 6 is started to run. The fan 6 can drive the external airflow into the main body 1 of the gene amplification instrument and blow it to the heat sink 3 and the circuit board 2 for heat dissipation. After the airflow takes away the heat, it can be discharged from the vent so that the airflow can circulate;

[0032] When the device needs to be repaired, the operator can hold the handle and then pull the pull ring with one finger to drive the two sets of pull rods 11 to move, and then drive the push block 15 through the pull rod 11 to push the push rod 14 to move. At this time, the push rod 14 can push the wedge-shaped plug 17 through the push block to overcome the elastic force of the spring B19 and pull it out of the slot 16, releasing the fixation of the cover body 7, and then the cover body 7 can be directly pulled out. At this time, the spring piece 8 can be disconnected from the electric contact block 9 to cut off the power of the fan 6, so that the cover body 7 can be quickly removed to repair and maintain the parts in the main body 1 of the gene amplification instrument. At the same time, after the cover body 7 is removed, it is convenient to repair and clean the fan 6;

[0033] After maintenance is completed, the cover 7 can be inserted into the main body 1 of the gene amplification instrument again. At this time, the wedge-shaped rod 17 can be automatically inserted into the slot 16 to fix the cover 7. At the same time, the spring piece 8 can automatically contact the electric contact block 9 to energize, which is very convenient for disassembly and assembly.

[0034] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

[0035] In the description of the present invention, unless otherwise specified, "multiple" means two or more; the terms "upper", "lower", "left", "right", "inner", "outer", "front end", "rear end", "head", "tail" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third" and the like are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0036] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A PCR gene amplifier that is easy to maintain, comprising a gene amplifier body (1) and a cover (7), characterized in that: A sample slot (5) is provided in the middle of one side of the top of the main body (1) of the gene amplification instrument; a heat cover (4) matching the sample slot (5) is provided on one side of the top of the main body (1) of the gene amplification instrument; a spring A (12) is provided on the other side of the top of the main body (1) of the gene amplification instrument; a heat sink (3) is provided at the bottom of the sample slot (5); the bottom of the heat sink (3) extends to the inside of the main body (1) of the gene amplification instrument; and a circuit board (2) is provided on one side of the inside of the main body (1) of the gene amplification instrument; A fan (6) is arranged on the inner side of the cover (7), a spring piece (8) is arranged on one side of the fan (6), a mounting plate (10) is arranged in the middle of one side of one end of the main body (1) of the gene amplification instrument, and an electric contact block (9) matching with the spring piece (8) is arranged in the middle of one side of the mounting plate (10); A slot (16) is provided on one side of the top and bottom of the cover body (7); a guide hole (18) is provided on one side of the inner top and bottom of the main body (1) of the gene amplification instrument; a wedge-shaped rod (17) matching with the slot (16) is slidably inserted into the inner side of two groups of the guide holes (18); springs B (19) are provided at the top and bottom of the two groups of the wedge-shaped rods (17) away from each other; an adjustment slot (13) is provided on the top and bottom of the cover body (7); a push rod (14) is sleeved on the inner side of the two groups of the slots (16); a pull rod (11) is sleeved on one side of the two groups of the adjustment slots (13); a push block (15) matching with the adjustment slot (13) is provided at one side of the two groups of the pull rods (11) away from the top and bottom.

2. The PCR gene amplifier easy to maintain according to claim 1, characterized in that: The top and bottom of one side of the cover body (7) are provided with handles.

3. The PCR gene amplifier easy to maintain according to claim 1, characterized in that: Stoppers are provided at the middle parts of the outer sides of the two groups of pull rods (11).

4. The PCR gene amplifier easy to maintain according to claim 2, characterized in that: One side of the two groups of pull rods (11) is provided with a pull ring, and the pull ring is located on the inner side of the handle.

5. The PCR gene amplifier easy to maintain according to claim 1, characterized in that: Ventilation holes are provided in the middle of both ends of the main body (1) of the gene amplification instrument.

6. The PCR gene amplifier easy to maintain according to claim 1, characterized in that: The tops and bottoms of the two groups of push rods (14) that are far away from each other are provided with pressure blocks.

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