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49results about How to "Significant activity" patented technology

Low-shrinkage, low-viscosity and ultrahigh strength concrete

The invention belongs to the technical field of building materials and particularly relates to low-shrinkage, low-viscosity and ultrahigh strength concrete. Based on a single formula proportional dosage, the low-shrinkage, low-viscosity and ultrahigh strength concrete comprises the following components by weight: 250-300kg of cement, 120-180kg of microspheres, 90-120kg of mineral powder, 820-860kg of machine-made sand, 950-1000kg of gravels, 7-11kg of a water reducer and 115-125kg of water. The components are mixed with stirring for 1.5-2 minutes to obtain a concrete mixture. The concrete provided by the invention is less in binding material use, the total shrinkage percentage is less than (0.03-0.04per mill), the emptying time of an inverted slump cone is 5-10 seconds, the viscosity of mortar in same proportion is 20-28 Mp.s, the 28d compressive strength is 110-130MPa, and the 56d compressive strength is 120-135MPa. The concrete has the characteristics of being low in bonding material use, short in stirring time, excellent in working performance and low in comprehensive cost, and can be produced on a large scale and has a broad application prospect.
Owner:中建商品混凝土(福建)有限公司 +1

Marine fungi aspergillus terreus C23-3, fermentation liquor active extract as well as preparation method and application thereof

InactiveCN108165500AImprove antioxidant capacityInhibits acetylcholinesterase activityFungiNervous disorderBiotechnologyBacterial strain
The invention relates to marine fungi aspergillus terreus C23-3, a fermentation liquor active extract as well as a preparation method and application thereof. The marine fungi aspergillus terreus C23-3 is collected in the Guangdong Microbiological Culture Collection Center (GDMCC) on Jan 22th, 2018 with the collection number GDMCC No. 60316. Active substances of standing fermentation liquor of theaspergillus terreus C23-3 are subjected to extraction and purification; a fermentation liquor total extract of a bacterial strain can well resist oxidization and restrain the activity of acetylcholinesterase; an active extract prepared by purifying the fermentation liquor of the bacterial strain has very high oxidization resistance and / or acetylcholin esterase restraining activity, and has a very good application prospect on the aspect of preparation of an anti-senile dementia medicament and on the aspect of preparation of an anti-oxidization and / or acetylcholin esterase activity restrainingmedicament.
Owner:SHENZHEN INST OF GUANGDONG OCEAN UNIV +1

Benzoyl fluoride benzene salicylamide compounds, preparation and application thereof

The invention provides a benzoyl fluorobenzene salicylamide compound and a preparation method and an application thereof. The benzoyl fluorobenzene salicylamide compound with a structure shown in a formula (I) is formed by the substitution reaction of benzoyl fluorobenzene salicyloylchloride as shown in a formula (III) and R1R2NH in an organic solvent at a temperature of between 0 and 160 DEG C. Derivatives of the benzoyl fluorobenzene salicylamide compound and the preparation method and the application thereof of the invention have the advantages of: (1) providing a novel anti-inflammatory and analgesic drug with remarkable anti-inflammatory and analgesic activities, and providing a research basis for selecting novel drugs; (2) simple preparation process and applicability industrialized production.
Owner:ZHEJIANG UNIV OF TECH

Application of Ypsilandra herbs for preparing medicines for treating hemorrhagic diseases

An application of the plants in Ypsilandra family in preparing the medicines for treating the hemorrhagic diseases (menorr hagia, postpartum hemorrhage, metrorrhagia, etc) is disclosed. Said plants are chosen from the Ypsilandra thibetica. Y.yunnanensis, Y.alpina, Y cavalevici, and Y kansuensis. Its advantages are high curative effect, low cost and high safety.
Owner:KUNMING INST OF BOTANY - CHINESE ACAD OF SCI

Periplaneta americana immunomodulating peptide and preparation method and medical application thereof

The invention relates to a periplaneta americana immunomodulating peptide and a preparation method and medical application thereof. Specifically, the invention relates to an immunomodulating peptide which is extracted from periplaneta americana and has the effects of preventing and treating tumor diseases and improving the immunity function of an organism. The polypeptide substance is a single chain polypeptide of which the amino acid sequence is arginine-arginine-asparagine-leucine-leucine-alanine-alanine-serine-leucine-leucine-asparagine- aspartate, and is prepared by extracting fresh or dry periplaneta americana in water or an organic solvent and a buffer solution and refining through a membrane separation method and an HPLC (High Performance Liquid Chromatography) technology. The immunomodulating peptide has remarkable antitumor activity and immunomodulating effect, and can be used to make medicaments for preventing and treating tumor diseases and / or modulating immunity, daily chemical products or medical devices.
Owner:DALI UNIV

Long-acting disinfecting nitrous acid compositions and related processes

The invention relates to long-acting nitrous acid compositions that disinfect inanimate surfaces and animal tissues, and that can be used to treat diseases and wounds. Compositions of the invention are single-phase, metastable nitrous acid solutions that exhibit enhanced germicidal efficacy and can have an effective lifetime exceeding several years. Compositions of the invention have a wide variety of applications that include, but are not limited to, teat dips, oral rinses, instrument sterilization, and disinfection of food.
Owner:KROSS ROBERT D +1

Antrodia camphorata composition

The invention relates to an antrodia camphorate composition. The composition is prepared from the following components in parts by weight: 100-135 parts of antrodia camphorate mycelia, 12-18 parts of coenzyme Q10, 15-30 parts of gynostemma pentaphylla, 20-35 parts of pseudo-ginseng, 5-12 parts of American ginseng, 3-6 parts of wolfberry fruits and 20-40 parts of olive extract. The antrodia camphorate composition can be used for lowering the contents of total blood serum cholesterol, low-density lipoprotein cholesterol and triglyceride and improving the content of high-density lipoprotein cholesterol; the liver damage can be reduced and the liver function can be improved; and the antrodia camphorate composition has the effects of activating blood and removing blood stasis, lowering blood pressure and preventing cardiovascular and cerebrovascular events, and also has the effects of lowering blood glucose, improving the immunity and resisting tumors.
Owner:中山安荞生物科技有限公司

Rubimaillin/chitosan nanoparticle, and preparation method and application thereof

The invention discloses a rubimaillin / chitosan nanoparticle, and a preparation method and an application thereof. The nanoparticle is a three-dimensional reticular structure formed by crosslinking chitosan with sodium tripolyphosphate, rubimaillin is fixed in the nanoparticle in a molecular form, the rubimaillin encapsulation rate is 4.58-14.64%, the average particle size of the nanoparticle is 96-467nm, and the polydispersity index, the drug loading capacity and the Zeta potential of the nanoparticle are 0.25-0.27, 5.73-28.153[mu]g / mg and 45.07-48.73mV respectively. The preparation method of the rubimaillin / chitosan nanoparticle comprises the following steps: 1, preparing a chitosan component liquid; 2, preparing a rubimaillin component liquid; and 3, adding the rubimaillin component liquid into the chitosan component liquid in a dropwise manner, fully stirring, and adding an aqueous solution of sodium tripolyphosphate of 1.0-3.0mg / mL in a dropwise manner in order to prepare the rubimaillin / chitosan nanoparticle. The nanoparticle prepared in the invention has the advantages of regular shape, small particle size, good dispersion, and obvious anti-oxidation and cancer cell inhibition effects, and is a potential antioxidant and antitumor preparation.
Owner:WUHAN INSTITUTE OF TECHNOLOGY

Three flower fermentation original solution cosmetic, and preparation method thereof

The invention provides a three flower fermentation original solution cosmetic product. The three flower fermentation original solution cosmetic product is prepared from a zymophyte solution with a lactobacillus plantarum concentration ranging from 10<6> to 10<8>CFU / ml, peach flower powder, Flores Chamomillae powder, rose flower powder, glucose, and water. The invention also discloses a preparationmethod of the three flower fermentation original solution cosmetic product. The preparation method comprises following steps: peach flower powder, Flores Chamomillae powder, rose flower powder, water, and zymophyte are mixed so as to obtain an initial fermentation system, the obtained fermentation solution is subjected to disinfection and centrifugation so as to obtain a supernatant, wherein thesupernatant is the three flower fermentation original solution cosmetic product. According to the preparation method, lactic acid bacteria is adopted for full plant fermentation of the three kinds offlowers, so that all plant functional components and the activities are maintained, active component loss caused by extraction method is avoided, and plant natural activity is maintained. The three flower fermentation original solution cosmetic product is rich in components, such as kaempferol, trifolin, vitamins, amino acids, rose polyphenols, and quercitrin, with excellent antioxidation activityand inhibition activity on tyrosinase.
Owner:SHANGHAI INST OF TECH

Coumarin type derivative and application thereof

ActiveCN109232498ASignificant antitumor activitySignificantly PD-1Organic chemistryAntineoplastic agentsDiseaseCancer prevention
The invention provides a coumarin type derivative or pharmaceutically-acceptable salts thereof. The structural formula of the coumarin type derivative is shown as formula I (which is described in thespecification). The invention also discloses the pharmaceutically-acceptable salts of the coumarin type derivative. The compound provided by the invention has obvious anti-tumor activity and PD-1 / PD-L1 inhibiting activity, and can be used for preparing mediciens for treating or preventing cancer diseases and other proliferative diseases, so that the treatment or prevention of the cancer diseases and other proliferative diseases is realized.
Owner:HUAQIAO UNIVERSITY

Sea cucumber royal jelly capable of delaying aging and production method of sea cucumber royal jelly

InactiveCN107668569ASignificant activitySignificant swelling and pain relief effectFood ingredient functionsAdditive ingredientLactarius
The invention discloses sea cucumber royal jelly capable of delaying aging and a production method of the sea cucumber royal jelly. The sea cucumber royal jelly is characterized in that sea cucumber serosity made from food materials of fresh sea cucumbers and the like as raw materials cooperates with prepared royal jelly liquid, and then a traditional Chinese medicine extracting solution obtainedby decocting Chinese yams, radix astragali, mulberries, glossy ganoderma, red jujubes, Pseudo-ginseng, radix angelica sinensis, haws and radix acanthopanacis senticosi is added; and the sea cucumber royal jelly is made through the technological steps of performing mixing, performing filtering, performing homogenizing, performing concentration, performing sending to a fermenter, adding lactic acidbacteria of which the weight is 1-4% of that of the concentrated slurry, performing constant-temperature fermentation at 37-45 DEG C for 7-12 hours, performing filling, performing sealing, performingsterilization, and performing packing. The adopted formula is scientific, the adopted physical method and an enzymolysis technology are organically combined, nutrient components and bioactivity of food materials of the fresh sea cucumbers and the like are well reserved, and the adopted biological fermentation technique can increase the health-care effects of products. The sea cucumber royal jellyis good in mouth feel. Compared with a conventional sea cucumber royal jelly product, the sea cucumber royal jelly disclosed by the invention is better in nutrient and health-care effect, better in mouth feel, quicker and more convenient to eat, and has the efficacy of delaying aging.
Owner:威海健方医药研究所

Method for synthesizing cobalt-doped ferronickel mesh nanosheet array efficient bifunctional electrocatalyst and application

PendingCN111437819ASolve the problem of single catalytic performanceEfficient dual-function catalyticMetal/metal-oxides/metal-hydroxide catalystsElectrodesPtru catalystIron salts
The invention relates to a method for synthesizing a cobalt-doped ferronickel mesh nanosheet array efficient bifunctional electrocatalyst and application. The invention aims to solve the problem thatthe existing commercial hydrogen evolution reaction and oxygen evolution reaction catalyst is noble metal, high in price, poor in stability and limited in industrial application and the problem that the existing cheap ferronickel catalyst is complex in synthesis process, high in cost and single in catalytic performance and large-scale synthesis and application of the catalyst is thus seriously restricted. A simple two-pot hydrothermal method is adopted. Firstly, foamed nickel is pretreated, and then the pretreated foamed nickel is immersed into a nickel-iron salt solution, taken out after a hydrothermal reaction is conducted for a period of time, immersed into a cobalt salt solution for a hydrothermal reaction, taken out and dried to obtain the cobalt-doped ferronickel mesh nanosheet arrayefficient bifunctional electrocatalyst. The synthesis method is simple, convenient, low in cost, low in equipment requirement, capable of achieving large-scale production and suitable for industrialapplication. According to the method, the cobalt-doped ferronickel mesh nanosheet array efficient bifunctional electrocatalyst can be obtained.
Owner:BEIJING UNIV OF TECH

Bone strengthening pawpaw wine and preparation method thereof

The invention provides bone strengthening pawpaw wine. The pawpaw wine comprises the following raw materials: fragrant solomonseal rhizome, cape jasmine fruit, pawpaw, Chinese angelica, incised notopterygium rhizome and root, doubleteeth pubescent angelica root, dried tangerine peel, Chinese silkvine root-bark, Sichuan lovage rhizome, radix gentianae macrophyllae, medicinal cyathula root, safflower, Chinese taxillus herb, rhizoma homalomenae and leopard bone juice. With reasonable component composition and optimized dosages, each medicine in the pawpaw wine has a synergistic effect and has a good health care function for human bodies. The pawpaw wine especially has obvious functions of dispelling wind and dampness and clearing and activating the meridians, and is used for treating tension of the sinews, condyle pain and numbness of limbs.
Owner:TIANJIN DARENTANG JINGWANHONG PHARMA

Shrinkage-resistant antibacterial nano composite fiber material for extracting uranium from seawater and preparation method of shrinkage-resistant antibacterial nano composite fiber material

The invention discloses a preparation method of a shrinkage-resistant antibacterial nano composite fiber material for extracting uranium from seawater. The shrinkage-resistant antibacterial nano composite fiber material for extracting the uranium from the seawater is prepared by blending a methoxypolyethylene glycol-b-polyarginine diblock copolymer with the mass concentration of 10-15% and a polypropylene amidoxime precursor solution with the mass concentration of 18.5%. In the method, an air spinning process is simple, and complicated equipment is not required. By the prepared nano compositefiber material, the strength of composite fibers is improved through electrostatic action, and shrinkage and degradation of amidoxime-based fibers are improved, thereby enhancing the stability and durability of the fibers in extracting the uranium from the seawater; the shrinkage-resistant antibacterial nano composite fiber material has remarkable antibacterial and anti-biofilm activity, the anti-biofouling performance of the fiber adsorption material in extraction of the uranium from the seawater is improved, and the adsorption sites are increased, so that the uranium adsorption capacity is improved.
Owner:HAINAN UNIVERSITY

Medicine for curing waist and leg pain and its preparing method

The invention relates to a pharmaceutical composition for treating waist and leg pains and process for preparation, wherein the medicament is prepared from wood louse, frankincense, myrrh, native copper, safflower, drynaria, rhubarb horsetails, borax and Chinese angelica root through steps of disintegrating, concentrating, granulating, and making capsule with pharmaceutically acceptable carriers or adjuvant.
Owner:刘会东

Far infrared thermal-sensing physical therapy paste and preparing method thereof

InactiveCN109999353ASmooth releaseImprove blood circulation systemLight therapyTherapeutic coolingFar infraredPolymer gel
The invention discloses a far infrared thermal-sensing physical therapy paste and a preparing method thereof. The far infrared thermal-sensing physical therapy paste comprises a non-woven fabric backlining layer, a gel layer and a stripping layer. The stripping layer is a CPP embossed film and is located on the upper layer of the gel layer. The non-woven fabric back lining layer is located on thelower side of the gel layer. The gel layer is composed of a polymer gel material and a thermal-sensing active material. On one hand, the thermal-sensing active material can collect the heat concentratedly generated within a certain period of time in a heating material and slowly release the heat by introducing a certain ratio of ultra-low-sulfur expansible graphite and bamboo charcoal powder, andtherefore human skin is prevented from being hurt by excessive heat; on the other hand, the thermal-sensing active material and far infrared ceramic beads have a synergistic thermal-sensing physicaltherapy effect, and therefore the human blood circulation system is greatly improved, and the functions of promoting blood circulation to remove blood stasis, relaxing tendons and activating collaterals, and eliminating swelling and easing pains are realized.
Owner:GUANGDONG TAIBAO MEDICAL SCI TECH

Rutin aliphatic ester derivatives, preparation method and application thereof

The invention provides rutin aliphatic ester derivatives, which are prepared by chemically synthesizing rutin and the aliphatic ester. The rutin aliphatic ester derivatives have an easily-obtained raw material, low cost, simple preparation method and high yield, and are suitable for industrialized production. The pharmacological test shows that the rutin aliphatic ester derivatives have obvious effect for inhibiting platelet aggregation and inhibiting the activity of hepatitis virus, and can be used for preparing an anti-angiocardiopathy medicine, an anti-cerebrovascular disease medicine, an anti-viral hepatitis B medicine and an anti-hepatitis C medicine.
Owner:上海双科医药科技有限公司

Naphtho thiophene diketone compound and preparation method and application thereof

The invention discloses a naphthothiophene diketone compound with antitumor activity from marine Streptomyces, and a preparation method and application thereof. The structure of the compound is shownin formula I, the compound belongs to a novel structural compound containing sulfur, has significant protein kinase inhibitory activity and anti-tumor activity, can effectively inhibit protein kinasePKC, ROCK2 and the like, can be used for development as a kinase inhibitor; and the compound has a good therapeutic prospect for cancers such as lung cancer, gastric cancer, breast cancer, lymphatic cancer, PDGF dependent tumors and the like. The invention further discloses the preparation method of the compound with antitumor activity, the compound is produced by solid fermentation of marine actinomycetes, through extraction by ethyl acetate or dichloromethane, the culture product is extracted, then through separation and purification by silica gel column chromatography, gel column chromatography and reversed phase chromatography, the compound is obtained, and the method is easy to operate and carry out. The formula I is shown in the description.
Owner:ZHEJIANG UNIV

Multi-effect traditional Chinese medicine toothpaste and preparation method thereof

The invention discloses multi-effect traditional Chinese medicine toothpaste and a preparation method thereof, and relates to the technical field of toothpaste. The multi-effect traditional Chinese medicine toothpaste comprises the following components in parts by weight: 3-9 parts of poria cocos extract, 0.5-1.5 parts of radix salviae miltiorrhizae extract, 0.5-1.5 parts of pseudo-ginseng extract, 0.5-1.5 parts of vernonia amygdalina extract and 88-96 parts of toothpaste matrices. The multi-effect traditional Chinese medicine toothpaste is scientific and reasonable in structure and convenientto operate; poria cocos is added into the raw materials, is a medicinal and edible treasure and has an important nourishing effect; Chinese herbal medicine active ingredients including radix salviaemiltiorrhizae and pseudo-ginseng are added into the formula, the multi-effect traditional Chinese medicine toothpaste is prepared through compatibility according to the theory of traditional Chinese medicine, and the effect of treating both symptoms and root causes of heart-spleen deficiency diseases is jointly achieved. The medicine dissolves into saliva by brushing teeth every day, permeates, diffuses and is absorbed through oral mucosa, sublingual capillaries and meridian points, and directly enters blood circulation; and the multi-effect traditional Chinese medicine toothpaste is used forreplacing medicines taken by a patient suffering from heart-spleen deficiency diseases for a long time, improves oral inflammation and has a remarkable health-care effect.
Owner:冼国茂

Pain stasis and paralysis eliminating powder for treating soft tissue injury

ActiveCN102302564ASignificant activitySignificantly reduce swelling and relieve painAntipyreticAnalgesicsEffective treatmentActive ingredient
The invention relates to pain stasis and paralysis eliminating powder for treating soft tissue injury. The pain stasis and paralysis eliminating powder is mainly prepared from the following raw material drugs in parts by weight: 400 to 600 parts of rhubarb, 400 to 600 parts of frankincense, 400 to 600 parts of pseudo-ginseng, 725 to 925 parts of kadsura rootbark, and 650 to 850 parts of angelica.The invention also provides application of the pain stasis and paralysis eliminating powder for treating soft tissue injury. The pain stasis and paralysis eliminating powder has the advantages that: the pain stasis and paralysis eliminating power is compatible with a principle of Chinese medicament 'monarch, minister, assistant and guide'; and pharmacodynamic tests prove that the pain stasis and paralysis eliminating powder has the remarkable effects of activating blood and eliminating stasis, and reducing swelling and relieving pain. The powder is used for treating pains and swelling caused by acute and chronic soft tissue injuries, lumbar sprain, stiff neck and gonarthromeningitis, has small toxic or side effect, remarkable curative effect, low cost and is safe to administer convenient to manufacture, suitable for long-term use and easy for wide popularization, and thus the pain stasis and paralysis eliminating powder is a safe and effective external medicament for treating acute and chronic soft tissue injuries.
Owner:XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Pegylation hypoglycemic polypeptide and preparation method and application thereof

The invention discloses pegylation hypoglycemic polypeptide. The pegylation hypoglycemic polypeptide has an amino acid sequence as shown by the sequence 1 (SQDID NO:1): His-Gly-Glu-Gly-Xaa1-Phe-Thr-Ser-Asp-Leu-Ser-Xaa2-Xaa3-Xaa4-Glu-Glu-Glu-Ala-Va1-Xaa5-Leu-Phe-I le-Glu-Trp-Leu-Xaa6-Xaa7-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-Xaa8; and a side-chain hydrosulfide group of C-terminal amino acidXaa8 of the hypoglycemic polypeptide is in covalent linkage with polyethylene glycol. The GLP-1 receptor stimulating agent activity of the pegylation hypoglycemic polypeptide is higher than that of aGLP-1 prototype molecule. A peptide sequence of the molecule does not contain recognition sites of dipeptidyl peptidase and neutral peptidase and has high stability. Besides, due to the masking action of the polyethylene glycol, the immunogenicity of a modified peptide molecule is basically eliminated, and when the polyethylene glycol of which the molecular weight is over 20 kDa is adopted to perform modification, the pharmacokinetic half-life of the pegylation hypoglycemic polypeptide can be over 48 hours.
Owner:CHINA PHARM UNIV

Rice bean flavone extracts and their use

An adzuki bean total flavone extract and its use are disclosed. The extract consists of Catechine, Rutin, Myricetin-rutinoside and Quercetin. The preparation style consists of liquid preparation and solid preparation, medicine feeding style consists of oral medicine feed and non-intestinal tract feed. Its advantages include prevention, health-care, anti-senility, colorful sources and high safety.
Owner:ZHEJIANG UNIV

Preparation method of fly ash-sodium alginate composite adsorption material

The invention discloses a preparation method of a fly ash-sodium alginate composite adsorption material. Fly ash is taken as the raw material and is activated and separated. Because fly ash has a goodpore structure, during the process of water bloom reactions, abundant hydroxyl groups appear on the surface of fly ash particles, thus fly ash will have a prominent hydrophilic performance, adsorbingperformance, and surface chemical activity; then the fly ash is modified by functional groups to prepare functional fly ash; then functionalized fly ash and sodium alginate are used to prepare the granular composite adsorption material; the synergetic effect between the functional fly ash and abundant functional groups (COO- groups) on the surface of sodium alginate is fully exerted; the adsorption material can be used to adsorb heavy metal ions with positive charges, such as Cu<2+>, Ni<2+>, Zn<2+>, Pb<2+>, Cd<2+>, and the like; the production cost is low, the fly ash is converted into valuable resources; the specific surface area of activated fly ash is increased by 15 to 20 times, the adsorbing performance is greatly enhanced, the prepared composite material can be desorbed and repeatedly used and can avoid secondary pollution, and the processing cost is reduced.
Owner:SHENZHEN HONGKONG INSTITUTION OF IND EDUCATION & RES ENVIRONMENTAL ENG TECH CO LTD +1

Drug for treatment of rheumatism, stroke and other diseases and preparation method thereof

The present invention relates to the technical field of medicines, and particularly relates to a drug for treatment of rheumatism, stroke and other diseases and a preparation method thereof; the drug comprises the following components: radix aconiti agrestis, Radix Aconiti, Polygonum multiflorum, frankincense, Typhonium giganteum Engl, aconite, monkshood, pig's trotters and rock candy, the preparation method comprises the following steps: 1) processing with water and cutting; 2) hydrolyzing for extraction and detoxification; and 3) concentrating to obtain paste; through the improvement of the preparation method, especially vinegar frying of the frankincense, toxic ingredients in the radix aconiti agrestis and the Radix Aconiti can be completely removed, and the added frankincense and licorice are cooperated with main medicines in the formula, so that a better rheumatism treatment effect can be achieved.
Owner:YUNNAN JINWUHEI PHARMA

Traditional Chinese medicine composition for treating rheumatism bone disease, and preparation method and application of Chinese patent medicines

InactiveCN103585275ASignificant effectSignificant effect of promoting blood circulation and removing blood stasisOrganic active ingredientsAntipyreticCyathula officinalisJoint arthralgia
The invention discloses a traditional Chinese medicine composition for treating rheumatism bone disease. The traditional Chinese medicine composition comprises the active parts by the mass percentage: 40%-60% of glycyrrhizin, 10%-20% of licoflavone, 5%-20% of ephedra alkaloids, 5%-20% of radix cyathulae saponins, and 5%-10% of strychnos alkaloids. A method for preparing Chinese patent medicines according to the traditional Chinese medicine composition comprises the following steps: (1) preparing the glycyrrhizin; (2) preparing the licoflavone; (3) preparing the ephedra alkaloids; (4) preparing the radix cyathulae saponins; (5) preparing the strychnos alkaloids; (6) preparing the active part composition; and (7) producing the Chinese patent medicines for treating rheumatism bone disease. The Chinese patent medicines comprise capsules, soft capsules and tablets. The Chinese patent medicines prepared according to the traditional Chinese medicine composition and used for treating rheumatism bone disease can be applied in easing pain, resisting inflammatory, promoting blood circulation, removing blood stasis, tonifying middle-jiao, replenishing qi, enhancing immunity and treating rheumatic arthritis and arthralgia caused by cold-dampness blocking meridians and collaterals.
Owner:EAST CHINA UNIV OF SCI & TECH

Culture method and application of bacillus subtilis

The invention provides a culture method and application of bacillus subtilis. The bacillus subtilis is a strain preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No.61565. A culture system is utilized to more accurately control the culture conditions of the bacillus subtilis, so that the generation of foam in the culture process is effectively reduced, the culture temperature and the dissolved oxygen content of culture are effectively controlled, and culture fermentation liquor with fewer impurities and higher activity is obtained; besides, after the bacillus subtilis is subjected to three-stage fermentation, metabolites of the bacillus subtilis have remarkable in-vitro and in-vivo prevention and treatment effects on the clostridium perfringens, the average diameter of an inhibition zone of the bacillus subtilis on the clostridium perfringens can reach 26.78 mm, and the prevention and treatment effect on the clostridium perfringens caused by the clostridium perfringens reaches 98.71%.
Owner:GUANGDONG HINAPHARM PHARMA CO LTD

Radix panacis quinquefolii preparation with fatigue-resisting and heart-curing effects and preparation method thereof

InactiveCN107232608ASignificant activitySignificant swelling and pain relief effectFood scienceDigestionBULK ACTIVE INGREDIENT
The invention discloses an anti-fatigue and heart-protecting American ginseng preparation and a preparation method thereof, which are characterized in that the active ingredients are made of American ginseng, Sanqi and Rhodiola rosea, and are also made of fresh American ginseng as raw materials. American ginseng extract, combined with Panax notoginseng extract and Rhodiola rosea extract, mixed, granulated, dried, granulated, then added magnesium stearate and mixed evenly, then filled into capsules, polished, packaged, and irradiated to sterilize Made into capsule preparations. The present invention adopts processing technologies such as the combination of pure physical means and heating ultrasonic hydrolysis treatment, so that the obtained product has high yield and good activity, helps to improve the nutritional value of the product, promotes the digestion and absorption of nutrients, and helps to improve the immune system. At the same time, it promotes the release of cell content and improves the effective utilization of American ginseng. The product has strong human immune function, anti-fatigue and anti-aging, and heart protection. It can be widely promoted and produced.
Owner:江苏新先制药有限公司

Three-color Furong honey powder

InactiveCN112618471AStrong anti-wrinklePowerful anti-agingCosmetic preparationsToilet preparationsGlycerolPolymethyl methacrylate
The invention discloses three-color Furong honey powder. The honey powder is prepared from the following components in percentage of 50-60% of silica, 20-25% of synthetic fluorophlogopite, 8-12% of aluminum starch octenylsuccinate, 4-6% of polydimethylsiloxane, 3-5% of polymethyl methacrylate, 0.9-1% of triethoxyoctylsilane, 0.1-0.3% of tocopheryl acetate, 0.01% of sodium hyaluronate, 0.01% of nicotinamide, 0.01% of jellyfish extract, 0.01% of a combination of water, glycerin and tripeptide-1 copper, 0.7% of phenoxyethanol, 0.1% of ethylhexylglycerin and 0.4-1% of a coloring agent, wherein the silica is spherical porous silicon dioxide, and the average particle size of the spherical porous silicon dioxide is 5-10 microns; and the refractive index of the spherical porous silicon dioxide is 1.544. The Furong honey powder has the technical effects of improving the skin fine line fading effect and the oil absorption and anti-oxidation effects.
Owner:广州卡洛莱化妆品有限公司

Anti-inflammatory and analgesic capsule with antrodia camphorata

The invention relates to an anti-inflammatory analgesic capsule. The preparation method comprises the following steps: firstly, treating the following medicinal materials: preparing various medicinal materials into powder, wherein the weight ratio of shortstalk monkshood root powder to nux vomica powder to pseudo-ginseng powder to safflower powder to raw liquorice powder is 1: (0.2-3): (0.4-0.5): (0.5-0.6): (0.7-0.8); uniformly mixing the treated medicine powder in proportion, and respectively filling into No.0 capsules. The traditional Chinese medicine composition has the advantages that the five medicines interact with one another, antagonize toxicity, enhance the drug effect, improve the neuroendocrine network regulation effect, inhibit abnormal generation of nitric oxide in macrophages, inhibit abnormal apoptosis of cells, realize the unique effect of traditional Chinese medicines, and solve the partial problems of inflammation resistance, immunity and analgesia; anti-inflammatory and analgesic effects are good and toxic and side effects are low.
Owner:冯学君
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