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49results about How to "Significant activity" patented technology

Rubimaillin/chitosan nanoparticle, and preparation method and application thereof

The invention discloses a rubimaillin/chitosan nanoparticle, and a preparation method and an application thereof. The nanoparticle is a three-dimensional reticular structure formed by crosslinking chitosan with sodium tripolyphosphate, rubimaillin is fixed in the nanoparticle in a molecular form, the rubimaillin encapsulation rate is 4.58-14.64%, the average particle size of the nanoparticle is 96-467nm, and the polydispersity index, the drug loading capacity and the Zeta potential of the nanoparticle are 0.25-0.27, 5.73-28.153[mu]g/mg and 45.07-48.73mV respectively. The preparation method of the rubimaillin/chitosan nanoparticle comprises the following steps: 1, preparing a chitosan component liquid; 2, preparing a rubimaillin component liquid; and 3, adding the rubimaillin component liquid into the chitosan component liquid in a dropwise manner, fully stirring, and adding an aqueous solution of sodium tripolyphosphate of 1.0-3.0mg/mL in a dropwise manner in order to prepare the rubimaillin/chitosan nanoparticle. The nanoparticle prepared in the invention has the advantages of regular shape, small particle size, good dispersion, and obvious anti-oxidation and cancer cell inhibition effects, and is a potential antioxidant and antitumor preparation.
Owner:WUHAN INSTITUTE OF TECHNOLOGY

Three flower fermentation original solution cosmetic, and preparation method thereof

The invention provides a three flower fermentation original solution cosmetic product. The three flower fermentation original solution cosmetic product is prepared from a zymophyte solution with a lactobacillus plantarum concentration ranging from 10<6> to 10<8>CFU/ml, peach flower powder, Flores Chamomillae powder, rose flower powder, glucose, and water. The invention also discloses a preparationmethod of the three flower fermentation original solution cosmetic product. The preparation method comprises following steps: peach flower powder, Flores Chamomillae powder, rose flower powder, water, and zymophyte are mixed so as to obtain an initial fermentation system, the obtained fermentation solution is subjected to disinfection and centrifugation so as to obtain a supernatant, wherein thesupernatant is the three flower fermentation original solution cosmetic product. According to the preparation method, lactic acid bacteria is adopted for full plant fermentation of the three kinds offlowers, so that all plant functional components and the activities are maintained, active component loss caused by extraction method is avoided, and plant natural activity is maintained. The three flower fermentation original solution cosmetic product is rich in components, such as kaempferol, trifolin, vitamins, amino acids, rose polyphenols, and quercitrin, with excellent antioxidation activityand inhibition activity on tyrosinase.
Owner:SHANGHAI INST OF TECH

Sea cucumber royal jelly capable of delaying aging and production method of sea cucumber royal jelly

InactiveCN107668569ASignificant activitySignificant swelling and pain relief effectFood ingredient functionsAdditive ingredientLactarius
The invention discloses sea cucumber royal jelly capable of delaying aging and a production method of the sea cucumber royal jelly. The sea cucumber royal jelly is characterized in that sea cucumber serosity made from food materials of fresh sea cucumbers and the like as raw materials cooperates with prepared royal jelly liquid, and then a traditional Chinese medicine extracting solution obtainedby decocting Chinese yams, radix astragali, mulberries, glossy ganoderma, red jujubes, Pseudo-ginseng, radix angelica sinensis, haws and radix acanthopanacis senticosi is added; and the sea cucumber royal jelly is made through the technological steps of performing mixing, performing filtering, performing homogenizing, performing concentration, performing sending to a fermenter, adding lactic acidbacteria of which the weight is 1-4% of that of the concentrated slurry, performing constant-temperature fermentation at 37-45 DEG C for 7-12 hours, performing filling, performing sealing, performingsterilization, and performing packing. The adopted formula is scientific, the adopted physical method and an enzymolysis technology are organically combined, nutrient components and bioactivity of food materials of the fresh sea cucumbers and the like are well reserved, and the adopted biological fermentation technique can increase the health-care effects of products. The sea cucumber royal jellyis good in mouth feel. Compared with a conventional sea cucumber royal jelly product, the sea cucumber royal jelly disclosed by the invention is better in nutrient and health-care effect, better in mouth feel, quicker and more convenient to eat, and has the efficacy of delaying aging.
Owner:威海健方医药研究所

Method for synthesizing cobalt-doped ferronickel mesh nanosheet array efficient bifunctional electrocatalyst and application

PendingCN111437819ASolve the problem of single catalytic performanceEfficient dual-function catalyticMetal/metal-oxides/metal-hydroxide catalystsElectrodesPtru catalystIron salts
The invention relates to a method for synthesizing a cobalt-doped ferronickel mesh nanosheet array efficient bifunctional electrocatalyst and application. The invention aims to solve the problem thatthe existing commercial hydrogen evolution reaction and oxygen evolution reaction catalyst is noble metal, high in price, poor in stability and limited in industrial application and the problem that the existing cheap ferronickel catalyst is complex in synthesis process, high in cost and single in catalytic performance and large-scale synthesis and application of the catalyst is thus seriously restricted. A simple two-pot hydrothermal method is adopted. Firstly, foamed nickel is pretreated, and then the pretreated foamed nickel is immersed into a nickel-iron salt solution, taken out after a hydrothermal reaction is conducted for a period of time, immersed into a cobalt salt solution for a hydrothermal reaction, taken out and dried to obtain the cobalt-doped ferronickel mesh nanosheet arrayefficient bifunctional electrocatalyst. The synthesis method is simple, convenient, low in cost, low in equipment requirement, capable of achieving large-scale production and suitable for industrialapplication. According to the method, the cobalt-doped ferronickel mesh nanosheet array efficient bifunctional electrocatalyst can be obtained.
Owner:BEIJING UNIV OF TECH

Shrinkage-resistant antibacterial nano composite fiber material for extracting uranium from seawater and preparation method of shrinkage-resistant antibacterial nano composite fiber material

The invention discloses a preparation method of a shrinkage-resistant antibacterial nano composite fiber material for extracting uranium from seawater. The shrinkage-resistant antibacterial nano composite fiber material for extracting the uranium from the seawater is prepared by blending a methoxypolyethylene glycol-b-polyarginine diblock copolymer with the mass concentration of 10-15% and a polypropylene amidoxime precursor solution with the mass concentration of 18.5%. In the method, an air spinning process is simple, and complicated equipment is not required. By the prepared nano compositefiber material, the strength of composite fibers is improved through electrostatic action, and shrinkage and degradation of amidoxime-based fibers are improved, thereby enhancing the stability and durability of the fibers in extracting the uranium from the seawater; the shrinkage-resistant antibacterial nano composite fiber material has remarkable antibacterial and anti-biofilm activity, the anti-biofouling performance of the fiber adsorption material in extraction of the uranium from the seawater is improved, and the adsorption sites are increased, so that the uranium adsorption capacity is improved.
Owner:HAINAN UNIVERSITY

Far infrared thermal-sensing physical therapy paste and preparing method thereof

InactiveCN109999353ASmooth releaseImprove blood circulation systemLight therapyTherapeutic coolingFar infraredPolymer gel
The invention discloses a far infrared thermal-sensing physical therapy paste and a preparing method thereof. The far infrared thermal-sensing physical therapy paste comprises a non-woven fabric backlining layer, a gel layer and a stripping layer. The stripping layer is a CPP embossed film and is located on the upper layer of the gel layer. The non-woven fabric back lining layer is located on thelower side of the gel layer. The gel layer is composed of a polymer gel material and a thermal-sensing active material. On one hand, the thermal-sensing active material can collect the heat concentratedly generated within a certain period of time in a heating material and slowly release the heat by introducing a certain ratio of ultra-low-sulfur expansible graphite and bamboo charcoal powder, andtherefore human skin is prevented from being hurt by excessive heat; on the other hand, the thermal-sensing active material and far infrared ceramic beads have a synergistic thermal-sensing physicaltherapy effect, and therefore the human blood circulation system is greatly improved, and the functions of promoting blood circulation to remove blood stasis, relaxing tendons and activating collaterals, and eliminating swelling and easing pains are realized.
Owner:GUANGDONG TAIBAO MEDICAL SCI TECH

Multi-effect traditional Chinese medicine toothpaste and preparation method thereof

The invention discloses multi-effect traditional Chinese medicine toothpaste and a preparation method thereof, and relates to the technical field of toothpaste. The multi-effect traditional Chinese medicine toothpaste comprises the following components in parts by weight: 3-9 parts of poria cocos extract, 0.5-1.5 parts of radix salviae miltiorrhizae extract, 0.5-1.5 parts of pseudo-ginseng extract, 0.5-1.5 parts of vernonia amygdalina extract and 88-96 parts of toothpaste matrices. The multi-effect traditional Chinese medicine toothpaste is scientific and reasonable in structure and convenientto operate; poria cocos is added into the raw materials, is a medicinal and edible treasure and has an important nourishing effect; Chinese herbal medicine active ingredients including radix salviaemiltiorrhizae and pseudo-ginseng are added into the formula, the multi-effect traditional Chinese medicine toothpaste is prepared through compatibility according to the theory of traditional Chinese medicine, and the effect of treating both symptoms and root causes of heart-spleen deficiency diseases is jointly achieved. The medicine dissolves into saliva by brushing teeth every day, permeates, diffuses and is absorbed through oral mucosa, sublingual capillaries and meridian points, and directly enters blood circulation; and the multi-effect traditional Chinese medicine toothpaste is used forreplacing medicines taken by a patient suffering from heart-spleen deficiency diseases for a long time, improves oral inflammation and has a remarkable health-care effect.
Owner:冼国茂

Pain stasis and paralysis eliminating powder for treating soft tissue injury

ActiveCN102302564ASignificant activitySignificantly reduce swelling and relieve painAntipyreticAnalgesicsEffective treatmentActive ingredient
The invention relates to pain stasis and paralysis eliminating powder for treating soft tissue injury. The pain stasis and paralysis eliminating powder is mainly prepared from the following raw material drugs in parts by weight: 400 to 600 parts of rhubarb, 400 to 600 parts of frankincense, 400 to 600 parts of pseudo-ginseng, 725 to 925 parts of kadsura rootbark, and 650 to 850 parts of angelica.The invention also provides application of the pain stasis and paralysis eliminating powder for treating soft tissue injury. The pain stasis and paralysis eliminating powder has the advantages that: the pain stasis and paralysis eliminating power is compatible with a principle of Chinese medicament 'monarch, minister, assistant and guide'; and pharmacodynamic tests prove that the pain stasis and paralysis eliminating powder has the remarkable effects of activating blood and eliminating stasis, and reducing swelling and relieving pain. The powder is used for treating pains and swelling caused by acute and chronic soft tissue injuries, lumbar sprain, stiff neck and gonarthromeningitis, has small toxic or side effect, remarkable curative effect, low cost and is safe to administer convenient to manufacture, suitable for long-term use and easy for wide popularization, and thus the pain stasis and paralysis eliminating powder is a safe and effective external medicament for treating acute and chronic soft tissue injuries.
Owner:XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Preparation method of fly ash-sodium alginate composite adsorption material

The invention discloses a preparation method of a fly ash-sodium alginate composite adsorption material. Fly ash is taken as the raw material and is activated and separated. Because fly ash has a goodpore structure, during the process of water bloom reactions, abundant hydroxyl groups appear on the surface of fly ash particles, thus fly ash will have a prominent hydrophilic performance, adsorbingperformance, and surface chemical activity; then the fly ash is modified by functional groups to prepare functional fly ash; then functionalized fly ash and sodium alginate are used to prepare the granular composite adsorption material; the synergetic effect between the functional fly ash and abundant functional groups (COO- groups) on the surface of sodium alginate is fully exerted; the adsorption material can be used to adsorb heavy metal ions with positive charges, such as Cu<2+>, Ni<2+>, Zn<2+>, Pb<2+>, Cd<2+>, and the like; the production cost is low, the fly ash is converted into valuable resources; the specific surface area of activated fly ash is increased by 15 to 20 times, the adsorbing performance is greatly enhanced, the prepared composite material can be desorbed and repeatedly used and can avoid secondary pollution, and the processing cost is reduced.
Owner:SHENZHEN HONGKONG INSTITUTION OF IND EDUCATION & RES ENVIRONMENTAL ENG TECH CO LTD +1

Traditional Chinese medicine composition for treating rheumatism bone disease, and preparation method and application of Chinese patent medicines

InactiveCN103585275ASignificant effectSignificant effect of promoting blood circulation and removing blood stasisOrganic active ingredientsAntipyreticCyathula officinalisJoint arthralgia
The invention discloses a traditional Chinese medicine composition for treating rheumatism bone disease. The traditional Chinese medicine composition comprises the active parts by the mass percentage: 40%-60% of glycyrrhizin, 10%-20% of licoflavone, 5%-20% of ephedra alkaloids, 5%-20% of radix cyathulae saponins, and 5%-10% of strychnos alkaloids. A method for preparing Chinese patent medicines according to the traditional Chinese medicine composition comprises the following steps: (1) preparing the glycyrrhizin; (2) preparing the licoflavone; (3) preparing the ephedra alkaloids; (4) preparing the radix cyathulae saponins; (5) preparing the strychnos alkaloids; (6) preparing the active part composition; and (7) producing the Chinese patent medicines for treating rheumatism bone disease. The Chinese patent medicines comprise capsules, soft capsules and tablets. The Chinese patent medicines prepared according to the traditional Chinese medicine composition and used for treating rheumatism bone disease can be applied in easing pain, resisting inflammatory, promoting blood circulation, removing blood stasis, tonifying middle-jiao, replenishing qi, enhancing immunity and treating rheumatic arthritis and arthralgia caused by cold-dampness blocking meridians and collaterals.
Owner:EAST CHINA UNIV OF SCI & TECH
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