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Method for evaluating quality of traditional Chinese medicine product

A technology for quality evaluation of traditional Chinese medicine products, used in measuring devices, instruments, scientific instruments, etc.

Active Publication Date: 2010-03-24
TIANJIN TASLY MORDEN TCM RESOURCES
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, combined with the visual comparison of the special case data of the simulated atlas, it can be known that these four corresponding similarity measures have certain evaluation bias or error limitations in the actual application of traditional Chinese medicine.

Method used

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  • Method for evaluating quality of traditional Chinese medicine product
  • Method for evaluating quality of traditional Chinese medicine product
  • Method for evaluating quality of traditional Chinese medicine product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] In this example, the application of existing examples of fingerprints of traditional Chinese medicinal materials is used to investigate and compare whether the results of the method of the present invention are consistent with those of the existing similarity evaluation methods, so as to test its rationality and feasibility. This embodiment adopts the sample fingerprints of 10 batches of gardenia extracts that have been demonstrated (referring to: Liu Yongsuo, Cao Min, Wang Yiming, etc., similarity system theory quantitatively evaluates the similarity of Chinese medicinal material chromatographic fingerprints, Analytical Chemistry, 2006, 34 (3 ): 333~337), see Table 1 for the original data. Table 2 shows the similarity evaluation results between the fingerprints of 10 batches of gardenia extract samples and the standard spectra calculated in the literature.

[0076] Table 110 batches of gardenia extract sample fingerprints raw data represent peak area value (unit: mAu) ...

Embodiment 2

[0099] In this embodiment, the fingerprints of the listed Compound Danshen Dripping Pills are used as an example for research. Using 10 batches of different batches of product samples produced by Tianjin Tasly Pharmaceutical Co., Ltd., the corresponding chromatographic fingerprints were measured by high performance liquid chromatography.

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Abstract

The invention discloses a method for evaluating the quality of a traditional Chinese medicine product, belonging to the technical field of traditional Chinese medicine. The method includes the following steps: obtaining a fingerprint atlas of a target traditional Chinese medicine product; calculating the equality degree according to a formula I based on the obtained fingerprint atlas and the standard fingerprint atlas of the traditional Chinese medicine product; and comparing the equality degree and a preset threshold value, if the equality degree E is not less than the threshold value, the traditional Chinese medicine product being qualified, otherwise, the traditional Chinese medicine product being defective. The formula for calculating the equality degree, provided by the method of theinvention, is a comprehensive improvement for each similarity calculating method in the prior art, can compensate for a plurality of limitations of the present similarity calculating method in the practical application of the traditional Chinese medicine, has a plurality of advantages, is suitable in a plurality of complex circumstances existing in the actual present situation of traditional Chinese medicine, and has wide application value.

Description

technical field [0001] The invention relates to a method for evaluating the quality of traditional Chinese medicine products, belonging to the technical field of traditional Chinese medicines. Background technique [0002] The identification method of Chinese medicine quality is a full reflection of the development level of Chinese medicine and the quality control level of Chinese medicine, and the corresponding methods and standards are the main basis for evaluating the quality and stability of Chinese medicine. The earliest traditional Chinese medicine was mainly based on traditional empirical identification, and the authenticity and quality of traditional Chinese medicine were judged according to the properties of the medicinal materials. After development, the four relatively mature quality identification methods of traditional Chinese medicine have gradually formed, namely, traditional empirical property identification method, morphology Gene source identification metho...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/86
Inventor 孙鹤谷瑞敏郭治昕
Owner TIANJIN TASLY MORDEN TCM RESOURCES
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