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Method for analysing an image of the brain of a subject, computer program product for analysing such image and apparatus for implementing the method

A computer program and brain image technology, applied in the field of computer program products and equipment for implementing the method, can solve problems such as unreliability, inability to give selection of regions of interest, and poor repeatability of known methods.

Inactive Publication Date: 2010-03-24
INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM)
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Problems solved by technology

[0008] In addition, known methods based on a comparison between a brain image of a subject and multiple brain images of a population do not give an accurate and objective selection of important regions of interest
[0009] Moreover, the known methods are poorly reproducible and even unreliable, since the collection of brain images by the above methods requires the use of the same equipment under the same conditions and the same settings in order to make possible distinctions and comparisons

Method used

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  • Method for analysing an image of the brain of a subject, computer program product for analysing such image and apparatus for implementing the method
  • Method for analysing an image of the brain of a subject, computer program product for analysing such image and apparatus for implementing the method
  • Method for analysing an image of the brain of a subject, computer program product for analysing such image and apparatus for implementing the method

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Embodiment Construction

[0021] In one embodiment, segmentation may include:

[0022] - normalization of the image, each voxel is assigned to a region of interest in a common template for region of interest segmentation in a common reference frame;

[0023] - Apply a non-linear transformation to the template for the above region of interest segmentation.

[0024] This non-linear transformation can include:

[0025] - inverse transform calculation for normalization processing,

[0026] - applying said inverse transformation to said region of interest segmented template.

[0027] The determination of the discriminant value may include: for each region of interest, calculating a plurality of relative parameters related to the image data, and establishing a discriminant value from a combination of the above relative parameters.

[0028] In a specific embodiment, determining the discriminant value may include: for each region of interest, identifying a group of voxels based on the image data of the voxe...

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Abstract

The invention provides a method for analysing an image of the brain of a subject, comprising: collection of an image in at least three dimensions of the brain of a subject, parcellation of said imageinto regions of interest (ROIs) in a brain native reference frame characteristic of said brain, determination in an automated manner, for each ROI, of at least one discriminating value based on imagedata measured on the image, said image data being representative of an anatomical or functional feature of the brain, said discriminating value being relative with regard to the discriminating valuesof the other ROIs.

Description

technical field [0001] The invention relates to a method for analyzing a brain image of a subject, as well as a computer program product for analyzing the image and a device for implementing the method. Background technique [0002] For brain studies, especially from a compositional, morphological, behavioral, or evolutionary perspective, a subject's brain can be visualized, for example, in three-dimensional or four-dimensional images. Brain images can then be processed and analyzed to identify reliable features representing anatomical or functional features of the brain that correspond to the measured image data. [0003] Brain images of multiple subjects can be distinguished from each other or classified into different groups based on the image data in certain applications. For example, the method described above can be used to compare an image in which data indicates that the brain has Alzheimer's disease (Alzheimer) with an image in which data indicates that the brain h...

Claims

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Application Information

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IPC IPC(8): G06T7/00
CPCG06T2207/10088G06T2207/20104G06T2207/30016G06T7/0014G06T7/0012G06T2207/10104G06T7/00
Inventor 哈比卜·贝纳利斯特凡娜·勒埃里西塞尔日·坎坎尼厄于恩伯努瓦·马尼安布律诺·迪布瓦
Owner INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM)
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