Traditional Chinese medicine for treating body-resistance-weak and pathogen-strong type chronic osteomyelitis and preparation method thereof

A technology for chronic osteomyelitis and the growth of positive and false evils. It is used in pharmaceutical formulations, medical preparations containing active ingredients, and bone diseases. It can solve the problems of decreased curative effect, easy recurrence, and drug resistance variation, and achieve exact curative effect, Less toxic and side effects

Inactive Publication Date: 2015-04-22
姜永杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the irrational use of antibiotics, pathogenic bacteria often have drug resistance and mutation, which reduces the curative effect
Although surgical treatment can remove the lesion, it has the disadvantage of easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0065] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine, wherein the dosage form of the traditional Chinese medicine for oral administration is a tablet, and the preparation method comprises the following steps:

[0066] Step 1: Mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 80-90% 3-5 times the mass of the mixture, heat and reflux for 1-2 hours, extract, and filter to obtain the first extract , add ethanol with an alcohol concentration of 80-90% relative to the mass of the medicinal residues that is 1 to 3 times the mass of the medicinal residues obtained by filtering, heat and reflux for 35 to 45 minutes, extract, and filter to obtain a second extract, mix the first extract with The second extracts were combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0067] The second step: put the d...

Embodiment 1

[0083] Embodiment 1: tablet

[0084] Take 340g of Achyranthes bidentata, 180g of Acanthopanax, 160g of Thousand Needles, 230g of Egg Ginseng, 310g of Xuefengteng, 120g of Shihua, 110g of Deer's Grass, 230g of Daxueteng, 160g of Duhuo, 110g of Evening Primrose, Lantana Flower 120g, elderberry 240g and fennel 110g;

[0085] Prepare as follows:

[0086] The first step: mix the various raw materials of the traditional Chinese medicine, add ethanol with an alcohol concentration of 90% that is 5 times the mass of the mixture, heat and reflux for 2 hours, extract, filter to obtain the first extract, and add the dregs obtained by filtering Ethanol with an alcohol concentration of 90% relative to the mass of the dregs is heated to reflux for 45 minutes, extracted, filtered to obtain the second extract, the first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried , to obtain dry paste;

[0087] The second step: pl...

Embodiment 2

[0089] Embodiment 2: capsules

[0090] Take 310g of Achyranthes bidentata, 160g of Acanthopanax, 190g of Thousand Needles, 220g of Egg Ginseng, 340g of Bloodwind Vine, 140g of Stone Flower, 130g of Deer's Grass, 210g of Great Blood Vine, 170g of Grass Duhuo, 130g of Evening Primrose, Lantana Flower 140g, elderberry 220g and fennel 130g;

[0091] Prepare as follows:

[0092] The first step is to mix the raw materials of the traditional Chinese medicine, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 60 minutes, extract, and filter to obtain the first extract; filter the obtained dregs and then add Ethanol with an alcohol concentration of 90% that is 3 times the mass of the dregs is heated to reflux for 30 minutes, extracted, and filtered to obtain the second extract; the first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried , to obtain dry p...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating body-resistance-weak and pathogen-strong type chronic osteomyelitis, and a preparation method thereof. The traditional Chinese medicine comprises a medicine for oral administration and a medicine for external use, wherein the medicine for oral administration comprises the following medicinal materials: radix achyranthis bidentatae, radix acanthopanacis semticosi, stellaria yunnanensis, codonopsis convolvulacea, ventilago leiocarpa benth, corallodiscus flabellatus, pyrola, sargentgloryvine stem, lovage, evening primrose, rhododendron delavayi, elderberry and rhizoma dioscoreae hypoglaucae; the medicine for external use comprises the following medicinal materials: pararuellia delavayana, cupparis spinosa, common andrographis herb, helwingia root, radix rubiae, siberian walking fern, paniculate spotflower herb, cryptolepis buchananii, fir club moss, radermachera sinica and cortex kadsurae radicis. The traditional Chinese medicine provided by the invention has the effects of combining oral administration and external use, strengthening the body resistance, eliminating pathogen, benefiting qi, nourishing blood, removing toxicity, promoting granulation, activating blood, dissolving stasis and relieving swelling and pains, has an extract curative effect for the body-resistance-weak and pathogen-strong type chronic osteomyelitis, and has slight toxic and side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating chronic osteomyelitis of deficiency of deficiency and excess of evil and its preparation method. Background technique [0002] Most chronic osteomyelitis develops as a result of inadequate or untimely treatment of acute osteomyelitis. However, if the pathogenic bacteria of acute osteomyelitis have low virulence or the patient's resistance is strong, it may be subacute or chronic osteomyelitis from the beginning, and osteomyelitis infected by skin wounds is often chronic osteomyelitis from the beginning . The pathogenic bacteria of chronic osteomyelitis is mainly Staphylococcus aureus pyogenes. Those with chronic sinuses often have a mixed infection of various bacteria. The disease is prone to occur in the metaphysis of long tubular bones in children. Most of them have a history o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61K36/74A61P19/00A61P7/00
Inventor 姜永杰李霞牛霞崔新艳王霞
Owner 姜永杰
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