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Silver nanowire-containing composition for biosensor strip, biosensor strip and its preparation method

A nano-silver wire and biological detection technology, which is applied in the direction of measuring devices, coatings, instruments, etc., can solve the problems of not being able to meet the needs of patients at the same time, and achieve the effect of ensuring uniformity

Active Publication Date: 2014-08-13
K CUBIC RES +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] As shown in Table 1 above, both carbon ink type and metal type biological detection sheets have their own shortcomings, and neither can meet the needs of patients at the same time

Method used

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  • Silver nanowire-containing composition for biosensor strip, biosensor strip and its preparation method
  • Silver nanowire-containing composition for biosensor strip, biosensor strip and its preparation method
  • Silver nanowire-containing composition for biosensor strip, biosensor strip and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0074] Preparation Example 1: Preparation of Silver Nanowire Composition

[0075] First, 100 ml of ethylene glycol (ethylene glycol) was preheated to 150°C, and then 2 g of silver nitrate (AgNO 3 ) and the PVP solution of 1.533 grams are poured in the ethylene glycol solution, and after heating several minutes, the nano-silver wire that the surface is coated with a very thick layer of PVP is made.

[0076] After that, the aforesaid silver nano wires are treated by centrifugation, so as to reduce the thickness of the PVP on the surface of the silver nano wires to the thinnest, that is, silver nano wires coated with hydroxyl compounds are obtained.

[0077] It is confirmed by experimental results that the silver nano wire coated with hydroxyl compound in this preparation example has 1.2×10 7 S / m conductivity.

[0078] see Figure 1 to Figure 3 As shown, the aspect ratio of the prepared nanosilver wire is about 200, and its diameter is mostly between 60 nm and 100 nm, and by ...

preparation example 2

[0082] Preparation Example 2: Preparation of biological detection sheet

[0083] First, a polyethylene terephthalate substrate is provided, and the polyethylene terephthalate substrate is preheated at a temperature of 70 to 80° C.

[0084] Afterwards, use the screen plate (its mesh number is 200mesh / inch) with the electrode pattern to be printed, the silver nano wire composition that each sample in Preparation Example 1 is made is coated on the opening on the screen plate and the electrode pattern place, the silver nano wire composition is coated on the polyethylene terephthalate substrate. Then, it is heated to 120° C. and dried for 30 minutes, and a conductive nano-metal layer with a thickness of about 50 microns is formed on the substrate after it is cured and formed.

[0085] Next, polyvinyl chloride is coated on the substrate and a part of the conductive nano-metal layer, and after drying, a protection layer is formed on the substrate and a part of the conductive nano-me...

Embodiment 1 to 5

[0087] Embodiments 1 to 5: biological detection sheet

[0088] The biological detection sheets of Examples 1 to 5 use the silver nanowire compositions of samples 1 to 5 prepared in Preparation Example 1 respectively, and obtain the biological samples of Examples 1 to 5 of the present invention through the steps described in Preparation Example 2. Detection sheet.

[0089] see Figure 4 and Figure 5 As shown, the biological detection sheet 1 prepared in each embodiment includes from bottom to top: a substrate 10 , a conductive nano-metal layer 20 , a protective layer 30 and a biological material layer 40 .

[0090] In various embodiments, the substrate 10 is a polyethylene terephthalate substrate.

[0091] The conductive nano-metal layer 20 is formed on the substrate 10 with a thickness greater than 4 microns and has an electrode pattern. Wherein, the electrode pattern includes a working electrode 21 , a reference electrode 22 and an auxiliary electrode 23 which are insula...

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Abstract

Provided is a silver nanowire-containing composition for a biosensor strip, a biosensor strip comprising the same and its preparation method. The biosensor strip comprises a conductive pattern layer (20) made of the silver nanowire-containing composition. With the aspect ratio of 50 to 500, the silver nanowire-containing composition has good dispersion and high conductivity, such that the biosensor strip comprising the same can have high stability and provide a more accurate and efficient detection.

Description

technical field [0001] The invention relates to a nano-silver wire composition for a biological detection sheet, a biological detection sheet and a manufacturing method thereof. Background technique [0002] With the advancement of medical science and technology, the average life expectancy of Chinese people continues to prolong, making chronic diseases gradually replace acute infectious diseases as one of the main causes of death for Chinese people. Among them, diabetes is the chronic disease with the highest attack rate among Chinese people. [0003] If diabetes is not diagnosed and treated early, diabetes will lead to many complications, such as retinopathy, nerve and vascular disease, and kidney disease, and even lead to blindness, amputation, high blood pressure, stroke and even death. Therefore, how to track and manage the blood sugar and blood pressure of patients on a long-term and regular basis, control the condition of diabetes, and prevent or delay the occurrence...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B22F1/02G01N27/26
CPCG01N27/3272C09D139/06Y10T428/294Y10T428/2942
Inventor 孙文贤李厚毓柯世达柯景中
Owner K CUBIC RES
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