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Application of a medicinal composition containing Achyranthes bidentata

A composition and medicine technology, applied in the field of medicinal compositions containing Achyranthes, can solve the problems of aggravating toxicity, many impurities, harm to human body and environment, etc., and achieve the effect of obvious effect.

Active Publication Date: 2019-01-18
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The traditional drying method of Achyranthes bidentata is sulfur fumigation. Sulfur fumigation has a long history and plays an important role in the drying and storage of Achyranthes bidentata medicinal materials. However, sulfur fumigation of Achyranthes bidentata also has great problems. It affects the efficacy of the medicine, and sulfur fumigation will pollute the medicinal materials, aggravate the toxicity, and have certain harm to the human body and the environment
In the prior art, there is no report on the use of microwave and infrared technology in the extraction and preparation of pharmaceutical compositions containing Achyranthes bidentata, but the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient Taking it seriously affects the clinical application of this product

Method used

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  • Application of a medicinal composition containing Achyranthes bidentata
  • Application of a medicinal composition containing Achyranthes bidentata

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Take 20g of Achyranthes bidentata, 30g of Hanging Rock Wind, 10g of Hard Nine Zizilianhuancai, 20g of Red Back Leaf, 10g of Hairy Impeller Ring Vine, 20g of Caulis Spatholobi, 50g of Cassia twig, 15g of Mulberry Branch, 20g of Digu Bark, 5g of Licorice, take first Achyranthes bidentata was taken out when the moisture content of the medicinal material was 40% in an electric heating constant temperature blast drying oven under the condition of 60℃, then it was taken out when the moisture content of the medicinal material was 20% by microwave at 380V, 20-30mA. Dry the medicinal materials in an infrared heating device with moisture below 10%, take them out and let cool, combine with other medicinal materials, add 10 times the weight of the medicinal materials, soak for 0.5h, decoct for 1 hour, filter, and add 8 times the weight of medicinal materials to the medicinal residues Decocted for 1 hour, the medicinal solution was filtered out, combined the two decocted liquids, conc...

Embodiment 2

[0013] Take 20g of Achyranthes bidentata, 30g of Hanging Rock Wind, 10g of Rhodocarpus serrata, 20g of Red-backed Leaf, 10g of Hairy Impeller Ring Vine, 20g of Caulis spatholobi, 50g of Cassia twig, 15g of Mulberry Branch, 20g of Earth Bone Bark, 5g of Licorice, take first Achyranthes bidentata was baked in an electric heating constant temperature blast drying oven at 60°C until the moisture content of the medicinal material was 40%, then taken out by microwave at 380V, 20-30mA until the moisture content of the medicinal material was 20%, and then set Dry the medicinal materials in an infrared heating device with moisture below 10%, take them out and let cool, combine with other medicinal materials, add 10 times the weight of the medicinal materials, soak for 0.5h, decoct for 1 hour, filter, and add 8 times the weight of medicinal materials to the medicinal residue Decocted for 1 hour, the medicinal solution was filtered out, combined the two decocted liquids, and concentrated u...

Embodiment 3

[0015] Take 20g of Achyranthes bidentata, 30g of Hanging Rock Wind, 10g of Hard Nine Zizilianhuancai, 20g of Red Back Leaf, 10g of Hairy Impeller Ring Vine, 20g of Caulis Spatholobi, 50g of Cassia twig, 15g of Mulberry Branch, 20g of Digu Bark, 5g of Licorice, take first Achyranthes bidentata was taken out when the moisture content of the medicinal material was 40% in an electric heating constant temperature blast drying oven under the condition of 60℃, then it was taken out when the moisture content of the medicinal material was 20% by microwave at 380V, 20-30mA. Dry the medicinal materials in an infrared heating device with moisture below 10%, take them out and let cool, combine with other medicinal materials, add 10 times the weight of the medicinal materials, soak for 0.5h, decoct for 1 hour, filter, and add 8 times the weight of medicinal materials to the medicinal residues Decocted for 1 hour, the medicinal solution was filtered out, combined the two decocted liquids, and ...

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Abstract

The invention discloses a medicine composition containing radix achyranthis bidentatae. The medicine composition contains radix achyranthis bidentatae and other medicine materials, and radix achyranthis bidentatae is processed through an electric heating constant-temperature air dry oven, a microwave and infrared heating device and the like. The invention further discloses application of the medicine composition containing radix achyranthis bidentatae in preparation of rheumatic arthritis treating medicine.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition containing achyranthes bidentata and its application. Background technique [0002] The traditional drying method of Achyranthes bidentata is sulfur fumigation. Sulfur fumigation has a long history and has a significant effect on the drying and storage of Achyranthes bidentata medicinal materials. However, there are also big problems with the sulfur fumigation of Achyranthes bidentata, which may not only change the chemical composition of Achyranthes It affects the efficacy of the medicine, and sulfur fumigation will pollute the medicinal materials, increase the toxicity, and have certain harm to the human body and the environment. In the prior art, there has not been a report on the use of microwave and infrared technology in the extraction and preparation of pharmaceutical compositions containing achyranthes bidentata. H...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P29/00A61P19/02
CPCA61K36/21A61K36/47A61K36/484A61K36/486A61K36/54A61K36/59A61K36/605A61K36/815A61K36/87A61K36/898A61K2236/17A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 李伟东王恒陆兔林陈志鹏高倩倩赵根华
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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