Apparatus and method for organ perfusion

An organ and perfusate technology, applied in the field of custom-controlled devices, can solve the problems that organs are not used for transplantation, are not suitable for transplantation, and their functions are not fully preserved or restored.

Active Publication Date: 2017-08-01
TEVOSOL INC
View PDF21 Cites 16 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Despite advances in perfusion techniques to date, the majority of donated organs have not been used for transplantation for a number of reasons
For example, the function of some harvested organs is not sufficiently preserved or restored to make them unsuitable for transplantation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Apparatus and method for organ perfusion
  • Apparatus and method for organ perfusion
  • Apparatus and method for organ perfusion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0037] In overview, it has been recognized that multiple pumps can be advantageously used in an ex vivo perfusion device, not only for cardiac perfusion, but also for lung perfusion or perfusion of other organs, to achieve improved flow control to allow better Simulate blood circulation in intact organs and assess organ condition. The fluidic subsystem with the pump and the control subsystem can conveniently be provided in a base unit that can be coupled to different organ-specific modules. The inclusion of multiple pumps allows the base unit to be conveniently configured and adapted to work with various organ-specific modules to perfuse different types of organs, eg heart, lungs, liver or kidneys.

[0038] For example, to perfuse a resected lung, a first pump may be used to apply preload pressure to drive perfusate into the pulmonary artery of the lung, and a second pump may be used to maintain afterload pressure against flow of perfusate from the pulmonary vein of the lung. ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

Apparatus for perfusion of multiple types of organs include base unit configured to removably couple with a perfusion module for perfusing an organ. The base unit has conduits for connecting a source of a perfusate to the organ to circulate the perfusate through the organ; first and second pumps coupled to the conduits for driving circulation of the perfusate in the conduits; and a controller configured and connected for controlling the first and second pumps to regulate the circulation of the perfusate through the organ. The controller is operable to control the first and second pumps to perfuse the organ in accordance with organ specific perfusion parameters. The organ specific perfusions parameters are selected based on the type of the organ, and may be selected by an operator for at least two organ types selected from the group of heart, liver, kidney and lung.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit and priority of US Provisional Patent Application No. 62 / 090984, filed December 12, 2014, which is hereby incorporated by reference in its entirety. technical field [0003] The present disclosure relates generally to organ perfusion devices and methods, and in particular to devices and methods for customized control of perfusate flow using fluid pumps for different types of organs (eg, heart, lung, liver, or kidney). Background technique [0004] Organ perfusion is a useful technique, especially for preserving, testing and evaluating donated organs for transplantation. For example, different perfusion devices, systems and methods have been developed for ex vivo maintenance and transport of harvested organs. After harvesting an organ for transplant from an organ donor, it is usually maintained ex vivo by perfusion for a period of time before transplanting it into a recipient. For e...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/02A61M1/00
CPCA01N1/0247
Inventor D·弗里德
Owner TEVOSOL INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap