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Composition for increasing bone mineral density and preparation method and application of composition

A technology for increasing bone density and composition, applied in the field of composition for increasing bone density of menopausal women and its preparation, can solve the problems of not increasing bone density, improve effective absorption rate, inhibit osteoclast differentiation, increase estrogen The effect of hormone secretion

Inactive Publication Date: 2020-03-20
BEIJING COMPETITOR SPORTS SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The raw materials involve common food raw materials, traditional Chinese medicinal materials, new resource foods, pharmaceutical excipients and other raw materials, b

Method used

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  • Composition for increasing bone mineral density and preparation method and application of composition
  • Composition for increasing bone mineral density and preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Ingredient content (parts by weight): 10 parts of milk mineral salt, vitamin K 2 0.6 parts of dry powder, vitamin D 3 0.05 parts of dry powder, 8 parts of marine fish skin collagen oligopeptide, 5.5 parts of hydrolyzed egg yolk powder, and 2.7 parts of epimedium extract.

[0024] The above-mentioned components are uniformly mixed to make a soft material, and then granulated, dried and sized to obtain a composition.

[0025] In the raw material formula of this example, add appropriate amount of water, 2.25 parts of sodium carboxymethyl starch, 11.5 parts of microcrystalline cellulose, and 0.4 parts of magnesium stearate, and mix the materials, granulate, dry, granulate, compress into tablets or not Tablets and other processes can be made into tablets or capsules.

Embodiment 2

[0027] Ingredient content (parts by weight): 25 parts of milk mineral salt, vitamin K 2 0.2 parts of dry powder, vitamin D 3 0.015 parts of dry powder, 5 parts of marine fish skin collagen oligopeptide, 3 parts of hydrolyzed egg yolk powder, 0.8 part of epimedium extract.

[0028] In the raw material formula of this example, add appropriate amount of water, 2.25 parts of sodium carboxymethyl starch, 8.335 parts of microcrystalline cellulose, and 0.4 part of magnesium stearate, and mix the materials, granulate, dry, granulate, compress into tablets or not Tablets and other processes can be made into tablets or capsules.

Embodiment 3

[0030] Ingredient content (parts by weight): 18 parts of milk mineral salt, vitamin K 2 0.4 parts of dry powder, 0.04 parts of vitamin D3 dry powder, 8 parts of marine fish skin collagen oligopeptide, 5 parts of hydrolyzed egg yolk powder, and 1.8 parts of epimedium extract.

[0031] In the raw material formula of this example, add appropriate amount of water, 2.25 parts of sodium carboxymethyl starch, 9.11 parts of microcrystalline cellulose, and 0.4 parts of magnesium stearate, mix the materials, granulate, dry, granulate, compress into tablets or not Tablets and other processes can be made into tablets or capsules.

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Abstract

The invention discloses a health food composition for increasing bone mineral density. The health food composition is characterized by comprising the following components in parts by weight: 5-33 parts of milk mineral salt, 0.1-0.6 part of vitamin K2 dry powder, 0.012-0.06 part of vitamin D3 dry powder, 5-12 parts of marine fish skin collagen oligopeptide, 3-6 parts of hydrolyzed yolk powder and 0.8-2.7 parts of an epimedium extract. According to the composition disclosed by the invention, aiming at osteoporosis metabolism and pathological characteristics of menopausal women, the milk mineralsalt is used as a high-quality calcium supplement source, a dual-channel absorption promoting factor is supplemented, the vitamin D assists in active transportation of calcium, and serine phosphate residues are negatively charged in an intestinal pH weakly alkaline environment and form a soluble compound with the calcium, so that the generation of insoluble precipitates is inhibited, the loss of the calcium is avoided, and the effective absorption rate of the calcium is improved. From the aspects of supplementing the calcium, promoting absorption, improving hormones, balancing bone cells and the like, according to the concept of combination of traditional Chinese medicines and western medicines, all the components are synergistic, and a purpose of enhancing the bone mineral density is achieved.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a composition for increasing the bone density of menopausal women, a preparation method and application thereof. Background technique [0002] Osteoporosis is a bone disease associated with aging, and its incidence increases with age. Studies have shown that in 2016, the prevalence of osteoporosis among the elderly over 60 years old in China was 36%, which has become an important public health problem facing our country. According to epidemiological surveys, in 2010, there were 2.33 million patients with osteoporotic fractures in my country, and the medical expenditure for this was 64.9 billion yuan. It is predicted that by 2050, the number of patients with osteoporotic fractures in my country will reach 5.99 million, and the corresponding medical expenditure will reach 174.5 billion yuan, especially in middle-aged and elderly women. More than 1 / 3 of the time will be postm...

Claims

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Application Information

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IPC IPC(8): A23L33/16A23L33/155A23L33/15A23L33/105A23L33/10A23L15/00
CPCA23L33/16A23L33/155A23L33/15A23L33/105A23L33/10A23L15/00A23V2002/00
Inventor 李奇庚魏冰朱玉丽
Owner BEIJING COMPETITOR SPORTS SCI & TECH