31 results about "Epimedium elatum" patented technology

This invention relates to the field of traditional Chinese medicine preparation technology, and discloses a Qingfu Chaijin granule, its preparation method, and its application. The Qingfu Chaijin granule comprises the following traditional Chinese medicine raw materials in parts by weight: Bupleurum chinense 8-12 parts, Cyperus rotundus 8-12 parts, Citrus reticulata peel 8-12 parts, Salvia miltiorrhiza 12-18 parts, Curcuma longa 8-12 parts, Angelica sinensis 8-12 parts, Ligusticum chuanxiong 5-8 parts, Foeniculum vulgare 8-12 parts, Amethyst 25-35 parts, Artemisia argyi 5-8 parts, Cistanche deserticola 8-12 parts, Epimedium brevicornu 8-12 parts, and Rehmannia glutinosa 8-12 parts. The invention also discloses the application of the aforementioned Qingfuchaijin granules in the preparation of drugs for relieving or treating dysmenorrhea caused by qi stagnation and blood stasis. By scientifically optimizing the compatibility ratio of Qingfuchaijin granules and combining it with a reasonable preparation process design, the resulting Qingfuchaijin granules have been significantly improved in terms of stability, user experience, and performance. The use of dry granulation or spray drying-dry granulation combined technology effectively reduces the initial moisture content of the granules, significantly reduces the hygroscopicity of the granules, and improves the storage stability of the product.

A new cultivar of Epimedium plant named ‘Little Bo Peep’ characterized by its compact dense habit and semi-evergreen tri-parted foliage with ovate leaflets that develop as light chartreuse with bronze-burgundy blush in the cooler spring and become medium green in the summer. Medium-sized flowers appear on panicles above the foliage starting in late spring with spurs having a light pinkish-purple tips and medium rose-colored centers, and pinkish-purple sepals. ‘Little Bo Peep’ is useful in the garden landscape as a specimen, en mass, or in containers.

This invention relates to the field of plant tissue culture and the breeding of superior varieties of traditional Chinese medicinal materials. This invention discloses a method for rapid propagation of Epimedium inflorescences via tissue culture, comprising the following steps: S1, collecting newly sprouted flower inflorescences of Epimedium in early spring, disinfecting them, and setting them aside; S2, cutting the disinfected inflorescences into 1.1-1.2 cm segments, inoculating them into callus induction medium, and culturing them under conditions of 1200-1300 lux light intensity, 12 h / day photoperiod, and 24℃. This invention ensures uniform seedling quality and stable traits through targeted screening of effective components and monitoring of genetic stability. The optimized culture medium ratios at each stage result in a high proliferation coefficient, robust rooting, and a short propagation cycle, enabling efficient year-round propagation. Standardized seedling hardening and transplanting lead to a high survival rate. This method is technically stable and highly applicable, enabling the mass production of high-flavonoid glycoside, genetically stable, high-quality seedlings, fundamentally solving problems such as germplasm degradation, low propagation coefficient, and uneven quality, providing strong support for the breeding and industrialization of superior varieties of Epimedium.

This invention relates to the fields of traditional Chinese medicine and anti-aging technology. The invention provides a scientifically formulated traditional Chinese medicine composition based on epigenetic guidance, its preparation method, and its application. The composition is made from the following raw materials in parts by weight: ginseng 3-12 parts, cordyceps 3-12 parts, polygonatum 2-8 parts, ganoderma lucidum 2-10 parts, mulberry fungus 2-6 parts, pine needles 1-6 parts, epimedium 2-8 parts, salvia miltiorrhiza 3-10 parts, bletilla striata 1-5 parts, cistanche deserticola 2-6 parts, rosemary 1-5 parts, and banana peel 1-6 parts. The composition is designed to comprehensively consider aging-related oxidative stress, energy metabolism regulation, and multi-component intervention needs, and is constructed in conjunction with epigenetic regulatory directions, reflecting the standardized design concept of scientifically formulated traditional Chinese medicine. The composition of this invention has the characteristics of clear composition, feasible preparation process, controllable quality parameters, and verifiable efficacy indicators.

The application discloses a kind of whole-process tracking management methods and systems for Epimedium sagittatum plantation, it is related to agricultural product management technical field, comprising: according to planting plot and planting time, generating planting batch number, constructing basic traceability file, based on agricultural key control point, obtain planting monitoring data, and association binding, set threshold to growth stage plant representation data, compare set threshold and planting node process file abnormal node, integrate planting node process file and abnormal disposal file, generate harvesting suitability score to determine planting batch, according to executable batch harvesting confirmation voucher, verify planting batch number, record postpartum quality data, input to planting node process file, and construct planting whole-process traceability file.The application is associated with binding by setting agricultural key control point and planting batch number, realizes the automatic acquisition of Epimedium sagittatum planting process data and whole-node traceability.

This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for treating intestinal injury. The traditional Chinese medicine composition comprises: 50-150 parts of ginseng, 60-180 parts of polygonatum, 40-90 parts of atractylodes, 30-58 parts of sophora flavescens, 60-180 parts of ophiopogon japonicus, 60-110 parts of rehmannia glutinosa, 40-90 parts of polygonum multiflorum, 60-180 parts of cornus officinalis, 40-90 parts of poria cocos, 35-58 parts of eupatorium fortunei, 35-58 parts of coptis chinensis, 35-90 parts of anemarrhena asphodeloides, 35-58 parts of epimedium, 40-110 parts of salvia miltiorrhiza, 60-180 parts of kudzu root, 80-140 parts of litchi seed, and 40-90 parts of lycium chinense root bark. The above-mentioned traditional Chinese medicine composition can inhibit the expression of TNF, AGE-RAGE, TLR and IL-17 and the infiltration of macrophages. It also helps to regulate the proliferation and differentiation of intestinal cells, restore beneficial bacteria in the intestine, and significantly improve the barrier function of the intestine, thereby effectively improving the damaged intestinal function.

This invention discloses a traditional Chinese medicine composition for treating liver fibrosis with damp-heat toxicity, comprising the following raw materials in parts by weight: 20-30 parts of processed turtle shell, 18-25 parts of Oldenlandia diffusa, 11-15 parts of Curcuma zedoaria, 20-30 parts of processed Salvia miltiorrhiza (wine-processed), 14-20 parts of Scutellaria barbata, 11-15 parts of Epimedium, 10-15 parts of Artemisia capillaris, 14-20 parts of Sedum sarmentosum, 7-10 parts of Bupleurum chinense, 7-10 parts of Curcuma longa, 6-8 parts of dried ginger, 11-15 parts of stir-fried Atractylodes macrocephala, 18-25 parts of Astragalus membranaceus, 7-10 parts of Prunus persica, 8-12 parts of Schisandra chinensis, 4-6 parts of Panax notoginseng (powder), 14-20 parts of Poria cocos, and 3-5 parts of Cinnamomum cassia. This traditional Chinese medicine composition is developed based on the principles of TCM syndrome differentiation and treatment for liver fibrosis with damp-heat toxicity, and has the expected therapeutic effect on this condition.

The application belongs to the technical field of traditional Chinese medicine detection, and specifically provides a construction method of a characteristic chromatogram of fatty acid components in Zhi Yinyanghuo and application thereof. The application screens gas chromatography conditions and a pretreatment procedure of a test sample through a large number of experiments, screens four characteristic peaks of fatty acids, and realizes effective separation of four characteristic peaks of methyl myristate, methyl palmitate, methyl oleate and methyl stearate, with good peak shape, stable baseline and high resolution, thereby providing a basis for quality detection and control of fatty acid components in Zhi Yinyanghuo and preparations thereof. Through methodology investigation, the precision and intermediate precision of the instrument are good, and the repeatability, specificity and durability of the method are good, thereby meeting the determination requirements. The method can also be used to distinguish raw products and processed products, and is helpful for accurate medication in clinic.

This invention belongs to the field of daily chemical products technology, and particularly relates to a hair-darkening composition, its preparation method, and its application. The hair-darkening composition provided by this invention is scientifically formulated with acetyl hexapeptide-1 and extracts of Polygonum multiflorum, Epimedium, and Aristolochia debilis root extract and Avena sativa seed extract. Through the synergistic effect of small molecule peptides and multiple plant active ingredients, it achieves multi-target and multi-pathway regulation of melanin production mechanisms. Each active ingredient, under specific ratios, exhibits significant synergistic effects, synergistically promoting melanin synthesis in hair follicles. Compared to single ingredients, it effectively enhances hair-darkening efficacy, providing a stable and efficient technical solution for improving gray hair and restoring its natural color, possessing outstanding practicality and application value.

A new cultivar of Epimedium plant named ‘Carnival Clown’ characterized by its medium-sized perennial habit and evergreen foliage with flowering in panicles beginning in the late spring that have spurs with yellowish tips and centers and bright orange in the middle. The sepals are vivid reddish-orange. The foliage has three lanceolate leaflets with small marginal teeth, with a light chartreuse with bronze coloring in cooler conditions and becoming deep green in summer.

The application discloses a kind of traditional Chinese medicine composition of soothing liver and dredging yang and consolidating foundation and cultivating yuan and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine.The traditional Chinese medicine composition is composed of red ginseng 6-9 parts by weight, dangshen 20-30 parts, fried atractylodes 20-30 parts, tuckahoe 10-20 parts, amomum villosum 6-10 parts, saussurea 9-18 parts, Sichuan cyathocline 20-28 parts, cassia twig 15-30 parts, herba rhizomatosi 6-10 parts, herba epimedii 10-20 parts, asarum 3 parts, centipede 1-3 parts.The preparation method can prepare various dosage forms such as granules, capsules and the like by processing, extracting and processing each raw medicinal material.The present application has scientific prescription, conforms to the overall concept of traditional Chinese medicine and the principle of treatment based on syndrome differentiation, can tonify heart and spleen, warm and dredge meridians, and arouse yang, is targeted to treat erectile dysfunction of heart and spleen deficiency and liver stagnation, has exact curative effect and high safety, has simple and controllable preparation process, low cost, is suitable for large-scale industrial production, and has high clinical promotion and industrialization value.

This invention relates to the field of traditional Chinese medicine extraction technology, specifically disclosing a method for ultrasonic extraction of flavonol glycosides from Epimedium using a eutectic solvent-assisted process. The method involves mixing choline chloride and glycerol, heating to prepare a eutectic solvent; mixing Epimedium leaf powder with a mixture of 70% ethanol and the eutectic solvent; ultrasonic extraction followed by centrifugation and filtration to obtain the Epimedium flavonol glycoside extract. The extraction method provided by this invention is green, efficient, and operates under mild conditions, resulting in good extraction effects. Compared with conventional ethanol ultrasonic extraction, the extracted icariin content is increased by 37.93%, and the total content of the three monomers is increased by 22.99%, providing technical support for the large-scale preparation and further development and utilization of Epimedium flavonol glycosides.

This invention discloses a multi-functional traditional Chinese medicine composition, an oral preparation, its preparation method, and its applications. The traditional Chinese medicine composition comprises the following components in parts by weight: Epimedium 2-8 parts, dried ginger 2-8 parts, licorice 2-8 parts, ginseng 1-4 parts, Poria cocos 1-4 parts, and Salvia miltiorrhiza 1-4 parts. This traditional Chinese medicine composition has multiple effects, simultaneously preventing and treating impotence, myocardial infarction, estrogen deficiency (typical estrogen deficiency such as postmenopause) related diseases (including osteoporosis, obesity, and uterine atrophy), and anti-fatigue effects, with significant efficacy and a very high degree of applicability. Moreover, the composition is simple, with all components being medicinal and edible herbs, ensuring high safety. It can be extracted using conventional water decoction methods to produce extracts, which can then be formulated into various oral preparations, including drugs, health foods (functional foods), or other food products, possessing significant market value.

This invention relates to a thin-layer chromatography (TLC) method for detecting *Pseudostellaria heterophylla* in a ginseng-pueraria lobata kidney-tonifying preparation. The raw materials of the preparation include *Pseudostellaria heterophylla*, kudzu root, and epimedium. The TLC method for detecting *Pseudostellaria heterophylla* in the preparation comprises the following steps: preparing a test solution and a *Pseudostellaria heterophylla* reference solution; spotting the test solution and the reference solution onto the same TLC plate, developing the solution in a developing solvent, adding a colorimetric reagent, and examining the sample; wherein the developing solvent is a mixture of 75% isopropanol and ethanol in a volume ratio of (1-9):1; and the colorimetric reagent is a mixed solution of aniline, diphenylamine, phosphoric acid, and acetone. This method can rapidly and accurately detect *Pseudostellaria heterophylla* in ginseng-pueraria lobata kidney-tonifying preparations, improving the accuracy and comprehensiveness of quality control and facilitating the establishment and overall evaluation of quality standards for these preparations.

This invention provides a fast-dissolving compound microcapsule powder of traditional Chinese medicine and its preparation method, belonging to the field of health food technology. The microcapsule powder preparation method includes: sequentially extracting a mixture of Epimedium powder, Hovenia dulcis powder, Cornus officinalis powder, Pueraria lobata root, Morus alba fruit, and Citrus reticulata peel with 55-60% ethanol for a first extraction, followed by a second extraction with water to adjust the ethanol concentration to 45-50%, obtaining a mixed extract; concentrating and drying to obtain a powder of the traditional Chinese medicine extract; mixing this powder with maltodextrin, citric acid, and stevia to prepare a core material powder; preparing a capsule material solution with gum arabic, β-cyclodextrin, and konjac gum; and coating the core material surface with the capsule material using a fluidized bed, followed by solidification to obtain the final product. This invention achieves efficient extraction of components with different polarities through a combination of gradient alcohol extraction and fluidized bed microencapsulation technology, significantly improving product stability, hygroscopic resistance, and solubility, effectively masking unpleasant odors. The resulting microcapsule powder has synergistic effects of anti-fatigue and kidney tonification, is convenient to take, and is suitable for the health product field.

This invention discloses a high-pressure synergistic extraction process for the combined active ingredients of mulberry leaf and epimedium, and a process for preparing functional granules. The process includes raw material pretreatment, high-pressure extraction, concentration, compounding, softening, granulation, and drying. Through the scientific combination of mulberry leaf and epimedium, the cold nature of mulberry leaf is neutralized to reduce gastrointestinal irritation, while the precise ratio avoids the risk of excessive heat caused by excessive epimedium intake, achieving a product with "synergistic effects of cold and heat, safe and mild," thus broadening the target population. The high-pressure room-temperature extraction technology shortens the extraction time by more than 80% and reduces energy consumption by 50% compared to traditional solvent extraction, significantly improving production efficiency. Simultaneously, the pure water solvent system is residue-free and pollution-free, ensuring product safety and conforming to green production principles. The flavonoids and DNJ, among other hypoglycemic active ingredients in mulberry leaf, synergistically interact with components such as icariin in epimedium, extending the product's efficacy from single-function hypoglycemia to multi-dimensional health benefits, meeting the diverse health needs of consumers.

The application provides a meridian-targeting theory-based traditional Chinese medicine preparation for treating prostatitis and a preparation method thereof. The preparation is composed of eighteen kinds of traditional Chinese medicines, including plantago seed, alisma orientalis, phellodendron, taraxacum, salvia miltiorrhiza, cyathula officinalis, eucommia ulmoides and epimedium etc. The cyathula officinalis, plantago seed and alisma orientalis are used as meridian-leading drugs to guide the active ingredients to flow down along the liver meridian of foot-Jueyin, the kidney meridian of foot-Shaoyin and the bladder meridian of foot-Taiyang, and target the prostate region. The whole preparation has the effects of clearing heat and reducing dampness, promoting blood circulation to remove blood stasis, soothing liver and regulating qi and tonifying kidney and consolidating the foundation, and is suitable for chronic prostatitis and benign prostatic hyperplasia of the type of lower-heat and kidney deficiency and blood stasis. The preparation can be prepared into various dosage forms such as capsules, granules and oral liquid. Experiments show that the preparation can significantly improve the urination symptoms and reduce the inflammation and fibrosis of the prostate, and has the advantages of strong targeting, definite curative effect, high safety and long-term use.

The application discloses a traditional Chinese medicine capsule of Herba Epimedii and Radix Morindae Officinalis and a preparation method thereof, relates to the technical field of traditional Chinese medicine preparations, and overcomes the defects of single-component preparation target, large side effect of hormone-containing drugs and unreasonable traditional compound prescription, etc.

The application provides a pharmaceutical composition, a preparation method and application thereof, and the pharmaceutical composition comprises a first component and a second component, the first component is a soft capsule, and the second component is a hard capsule or a tablet; the content of the soft capsule comprises total flavonoids of pueraria lobata and epimedium, an oily base, a surfactant and a suspending agent, and the second component comprises a panax notoginseng polysaccharide extract, a filler and a lubricant. The total flavonoids of pueraria lobata and epimedium are more easily absorbed in the oily base, so that the dissolution of the total flavonoids of pueraria lobata and epimedium is effectively improved, and the problem of low bioavailability of traditional water-soluble preparations is overcome; the panax notoginseng polysaccharide extract is placed in the hard capsule or the tablet, deformation caused by contact with the oily base is avoided, and therefore the activity and bioavailability of the panax notoginseng polysaccharide extract are ensured.

This invention relates to a fertilization method for improving the effective components in the traditional Chinese medicinal herb Epimedium brevicornu, specifically a fertilization method for Epimedium brevicornu, comprising: applying Bacillus subtilis and Bacillus thuringiensis or Trichoderma to the area to be planted with Epimedium brevicornu, wherein the Bacillus subtilis and Bacillus thuringiensis or Trichoderma are applied at a concentration of 1 g / m². 2 / Application of this invention can significantly increase the effective active ingredients in Epimedium brevicornu.

This invention discloses a linseed lignan-icariin compound solid beverage for the prevention or adjuvant treatment of osteoporosis and its preparation method, belonging to the field of functional food processing technology. The main active ingredient is a compound extract of linseed lignan and icariin, supplemented with sorbitol, maltodextrin, and β-cyclodextrin. Flaxseed and epimedium are mixed at a specific mass ratio, extracted using subcritical fluid technology, and purified with macroporous resin to obtain the compound extract; then encapsulated with β-cyclodextrin, and finally mixed with excipients and shaped. This method achieves efficient simultaneous extraction and stabilization of the active ingredients, with a simple process, resulting in a product with good solubility, good taste, and high stability. In vitro, this compound solid beverage effectively promotes osteoblast activity, inhibits osteoclast formation, regulates intestinal flora, and increases the production of beneficial metabolites such as short-chain fatty acids, indicating that it can enhance bone density through multiple pathways and can be used in the preparation of products for the prevention or adjuvant treatment of osteoporosis.

This invention provides a method for detecting kidney-tonifying and body-strengthening tablets, including thin-layer chromatography (TLC) to identify the effective components of Epimedium, Ligustrum lucidum, and Cuscuta chinensis in the tablets. The chromatographic identification method of this invention produces clear spots with good separation, eliminates interference from impurities, improves the controllability of the quality standards for kidney-tonifying and body-strengthening tablets, and further ensures the product's intrinsic quality and efficacy.

This invention relates to the field of medicinal plant cultivation technology and proposes a highly efficient method for the understory simulated ecological cultivation of Epimedium. The method includes: calculating the light limitation coefficient of the target seedlings in the understory simulated ecological environment; when the light limitation coefficient is greater than a preset light limitation threshold, subjecting the target seedlings to red and blue supplemental lighting treatment; calculating the rhizosphere growth-promoting bacteria colonization index of the target seedlings in the understory simulated ecological environment; when the rhizosphere growth-promoting bacteria colonization index is less than a preset growth-promoting bacteria colonization threshold, subjecting the target seedlings to targeted microbial community regulation treatment; calculating the water stress index of the target seedlings; when the water stress index is in the moderate stress range, subjecting the target seedlings to alternating irrigation treatment in the root zone; and implementing coordinated management of the plants after supplemental lighting, after rhizosphere regulation, and after water and fertilizer regulation throughout the entire growth period to obtain the target Epimedium. This invention enables the efficient cultivation of high-quality Epimedium germplasm.

The present application relates to the technical field of Chinese herbal medicine harvesting, and particularly relates to a harvesting device for Epimedium, which comprises a rack, a cutting mechanism, a sorting assembly, a collecting assembly, a screening assembly and a mode switching mechanism; the cutting mechanism is arranged at the front end of the rack; the sorting assembly comprises a vibration sorting module and an air sorting module, and is sequentially arranged behind the cutting mechanism; the collecting assembly comprises a leaf collecting box and a stem collecting box, which are respectively correspondingly arranged in a drop direction of an air sorting module discharge end and a vibration sorting module discharge end; the screening assembly is arranged in the leaf collecting box; the mode switching mechanism switches the working mode by switching the opening and closing of the baffle; the vibration sorting module and the air sorting module after cutting solve the technical problems that the existing Epimedium harvesting device cannot completely separate stems and leaves, has poor adaptability and cannot balance efficiency and purity.

The present application relates to the technical field of traditional Chinese medicine, and particularly relates to an anti-fatigue composition, which comprises the following raw materials in parts by weight: 5-15 parts of artemisia argyi, 10-20 parts of cistanche, 5-10 parts of pueraria, 5-15 parts of rehmannia, 10-20 parts of astragalus, 10-20 parts of epimedium, 12-18 parts of clove, 5-15 parts of psyllium, 5-12 parts of ginger, 5-15 parts of cassia, 5-12 parts of semen bellicidae, and 5-12 parts of licorice. The composition can supplement the body energy, has the functions of warming and tonifying kidney yang, strengthening muscles and bones, and regulating water passage, and can effectively relieve fatigue and improve the exercise endurance of the body.

The present application relates to the technical field of external treatment of traditional Chinese medicine, and specifically discloses a traditional Chinese medicine acupoint paste for regulating metabolism, a preparation method and application thereof. In view of the deficiency of the existing part of the metabolism regulation paste product in focusing on the function of a single Zang organ, the present application provides a traditional Chinese medicine acupoint paste based on the same regulation theory of liver, spleen and kidney. The paste is composed of the following medicinal materials in parts by weight: 20-30 parts of Radix Astragali, 12-15 parts of Radix Bupleuri, 15-20 parts of Herba Epimedii, 10-12 parts of Rhizoma Chuanxiong, 10-12 parts of Paeonia, 15-18 parts of Rhizoma Corydalis, 10-15 parts of Radix Atractylodis, 15-18 parts of Rhizoma Cyperi and 4-5 parts of Borneolum Syntheticum. The present application is used for the comprehensive regulation of the functions of liver, spleen and kidney through the synergistic effect of drugs and specific acupoints, and is suitable for the auxiliary regulation of the metabolic disorder state caused by liver stagnation, spleen dysfunction and kidney dysfunction.

The application discloses an extraction method for Epimedium extract, and relates to the technical field of traditional Chinese medicine extraction. The method comprises the following steps: firstly, freezing and crushing the raw material, and then adopting an ethanol solution to perform gradient temperature extraction, and through nonlinear decreasing solvent multiple, the energy consumption is reduced while the extraction rate is ensured; then, the extraction liquid is concentrated to a relative density of 1.10-1.15 and the residual ethanol is controlled to be 10%-15%, a metastable system with a specific alcohol-water ratio is constructed; after filtering out the fat-soluble impurities while hot, the effective components are directionally crystallized by using programmed temperature reduction, and finally, low-temperature washing and drying are performed to obtain the product. The method completely discards the complicated macroporous resin column chromatography process, effectively solves the problems of large solvent consumption, long production cycle and resin residue risk in the traditional technology, and is green and efficient, so that the cost is greatly reduced, and the high-purity and quality uniformity of the product are realized.

The application discloses a traditional Chinese medicine composition for senile dementia and stroke and a preparation method thereof, which is prepared from the following raw medicinal materials in parts by weight: 40 parts of Schinus molle, 10 parts of American ginseng, 8 parts of Panax notoginseng, 5 parts of hawthorn, 5 parts of Chinese yam, 5 parts of Herba Epimedii, 6 parts of Radix Curcumae, 5 parts of Poria cocos, 5 parts of Astragalus membranaceus, 5 parts of Codonopsis pilosula, 3 parts of Platycladus orientalis, 3 parts of Corydalis, and 5 parts of Cannabis sativa Linn. The application has the advantages that a nerve blood vessel unit system regulation mechanism is creatively proposed, the limitation of single target treatment is broken through, the Schinus molle, which is the monarch drug in the prescription, is rich in nervonic acid and neurotrophic factor-like substances, can directly act on neuron mitochondrial energy metabolism, improves brain tissue energy supply, and on the process level, the multi-stage dynamic extraction technology of the application innovates the traditional decocting mode.

This invention discloses a flavonol glycosyltransferase EsGT_F from *Epimedium sagittatum* and its applications. The EsGT_F gene provided by this invention is 1398 bp in length, encoding 466 amino acids. After cloning the *Epimedium sagittatum* flavonol glycosyltransferase gene EsGT_F, a prokaryotic expression system was constructed. The expressed protein exhibits flavonol glycosyltransferase activity, catalyzing the conversion of cymosin I to icariin. The *Epimedium sagittatum* flavonol glycosyltransferase and its encoding gene provided by this invention offer important gene elements and corresponding technical methods for the microbial cell factory production of the active ingredients of *Epimedium*, and have significant application prospects.