Application of turpinia arguta leaf extract in preparation of itching-relieving floral water

Abstract

The invention belongs to the technical field of hygienic products, and particularly relates to application of turpinia arguta leaf extract in preparation of itching-relieving floral water which is prepared from 6-10 parts of turpinia arguta leaf extract, 1-3 parts of mangnolia officinalis flower essential oil, 1-3 parts of menthol, 8-12 parts of propolis, 1-3 parts of cosolvent, 40-60 parts of ethyl alcohol and 30-50 parts of water. The itching-relieving floral water is prepared from natural main materials through a reasonable process, is mosquito-repelling and itching-relieving, has pleasant smell, is safe to human bodies, and has no toxic or side effect after long-term use.

Description

Technical Field

[0001] The invention belongs to the technical field of sanitary products, and particularly relates to use of a safflower leaf extract in preparing antipruritic floral water. Background Art

[0002] Summer is the season when mosquitoes reproduce faster and bacteria are more likely to breed. When human skin is bitten by mosquitoes or infected by bacteria, it is easy to cause itching, redness, swelling, inflammation, etc., and even cause diseases such as dengue fever. It will also affect sleep at night, make people upset, depressed and anxious, and have a great impact on human physical and mental health.

[0003] Floral water is a daily chemical product that is used frequently in daily life. In summer, people often spray floral water on their bodies to avoid mosquito bites. Generally, floral water is made by mixing a large amount of alcohol, water, essence and some specific chemical reagents to achieve the effect of repelling mosquitoes. Most of the floral waters currently available on the market contain active mosquito repellent ingredients such as chlorpyrifos, DEET, chlorpyrifos, and chlorpyrifos, which can cause potential harm to the digestive tract, respiratory tract, etc., induce diseases such as asthma, and even cause toxic side effects such as carcinogenicity and teratogenicity. In addition, menthol, borneol and other ingredients for short-term cooling and soothing, as well as salicylic acid compounds and other antibacterial and anti-inflammatory ingredients are added, but they are highly irritating and can easily cause skin allergies, dryness and itching. Summary of the invention

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and provide an antipruritic floral water made from natural raw materials, which not only has a long efficacy time but also has a preparation method suitable for industrial production.

[0005] To achieve the above object, the technical solution adopted by the present invention is as follows: Use of a safflower leaf extract in preparing an antipruritic floral water, the antipruritic floral water comprising 6 to 10 parts of safflower leaf extract, 1 to 3 parts of magnolia officinalis essential oil, 1 to 3 parts of menthol, 8 to 12 parts of propolis, 1 to 3 parts of a solvent, 40 to 60 parts of ethanol and 30 to 50 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of the Chinese yew are taken, crushed, immersed in deionized water and allowed to stand for 30 to 50 minutes, then adjusted to a pH of 5.8 to 6.2 with a NaAc-HAc buffer solution, and then added with a composite enzyme, and hydrolyzed for 20 to 30 minutes at a temperature of 45 to 50 degrees Celsius, inactivated at 100 degrees Celsius, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 40 to 90 minutes at an ultrasonic frequency of 80 kHz to 120 kHz and a temperature of 35 to 45 degrees Celsius, filtered, and the filtrate was dried under reduced pressure to obtain a Chinese yew leaf extract; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 40°C to 60°C, and then CO2 is introduced to completely replace the air; (3) Control the extraction pressure to 20MPa-30MPa and the CO2 gas flow rate to 30Kg / h-50Kg / h, and maintain for 60 minutes. After the extraction is completed, an extract is obtained; (4) Separating the extract to obtain Magnolia officinalis flower essential oil.

[0006] In a preferred example, the preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and the cosolvent, then add ethanol and menthol, add 50% of water while stirring, stir evenly, and obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 50℃~60℃, stir evenly, cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is antipruritic floral water.

[0007] In a preferred example, in the method for preparing the extract of the leaves of the safflower tree, the complex enzyme is prepared by mixing plant hydrolases and non-starch polysaccharide enzymes in a weight ratio of 1-2:1-2; Among them, the plant hydrolase is food grade with an enzyme activity of 10,000u / g; the non-starch polysaccharide enzyme is food grade with an enzyme activity of 10,000u / g to 20,000u / g.

[0008] In a preferred example, in the method for preparing the extract of the leaves of Scutellaria baicalensis, the conditions for reduced pressure drying are: temperature 45°C to 55°C, and vacuum degree 0.02MPa to 0.04MPa.

[0009] In a preferred example, in the preparation method of Magnolia officinalis flower essential oil, the extraction entrainer is 90% vol~96% vol ethanol, and its usage is 10%~15% of the weight of Magnolia officinalis flower.

[0010] In a preferred example, the co-solvent is one of glyceryl monostearate or glyceryl monolaurate.

[0011] Compared with the prior art, the antipruritic floral water of the present invention adopts natural main materials and is prepared through reasonable processes. It can repel mosquitoes and relieve itching, has a pleasant smell, is safe to the human body, and has no toxic side effects when used for a long time. DETAILED DESCRIPTION

[0012] In order to make the purpose, technical scheme and advantages of the present invention clearer, the present invention is further described in conjunction with specific embodiments, but the present invention is not limited to these embodiments. It should be noted that, under the premise of not conflicting, the embodiments described below or the technical features can be arbitrarily combined to form new embodiments. In the present invention, unless otherwise specified, all parts and percentages are mass units, and the equipment and raw materials used can be purchased from the market or are commonly used in the art. The methods in the following embodiments, if not otherwise specified, are conventional methods in the art.

[0013] As used herein, the terms "comprises," "including," "contains," or any other variation thereof, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises the listed elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.

[0014] When an amount, concentration, or other value or parameter is expressed as a range, a preferred range, or a range limited by a series of upper preferred values ​​and lower preferred values, this should be understood as specifically disclosing all ranges formed by any pairing of any range upper limit or preferred value with any range lower limit or preferred value, regardless of whether the range is disclosed separately. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted as including a range of "1 to 4", "1 to 3", "1 to 2", "1 to 2 and 4 to 5", "1 to 3 and 5" etc. When a numerical range is described in this article, unless otherwise specified, the range is intended to include its end values ​​and all integers and fractions within the range.

[0015] Example 1

[0016] An antipruritic floral water, comprising 10 parts of scutellaria baicalensis leaf extract, 1 part of magnolia officinalis flower essential oil, 3 parts of menthol, 8 parts of propolis, 3 parts of glyceryl monostearate, 40 parts of ethanol and 50 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of Scutellaria scabra were taken, crushed, immersed in deionized water and allowed to stand for 45 minutes, then adjusted to pH 6.1 with NaAc-HAc buffer solution, and then added with complex enzyme, hydrolyzed for 25 minutes at 48°C, inactivated at 100°C, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 75 minutes at an ultrasonic frequency of 110KHz and a temperature of 40°C, filtered, and the filtrate was dried under reduced pressure at a temperature of 50°C and a vacuum degree of 0.03MPa to obtain a Scutellaria scabra leaf extract; The compound enzyme is prepared by mixing plant hydrolase and non-starch polysaccharide enzyme in a weight ratio of 2:1, wherein the plant hydrolase is food grade with an enzyme activity of 10000u / g; the non-starch polysaccharide enzyme is food grade with an enzyme activity of 15000u / g; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 52°C, and then CO2 is introduced to completely replace the air; (3) The extraction pressure is 25 MPa, the CO2 gas flow rate is 45 kg / h and maintained for 60 min. After the extraction is completed, an extract is obtained; (4) separating the extract to obtain Magnolia officinalis flower essential oil; The extraction entrainer is 95% vol ethanol, and its dosage is 12.5% ​​of the weight of Magnolia officinalis flower; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and glyceryl monostearate, then add ethanol and menthol, add 50% of water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 56°C, stir evenly, and cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is an antipruritic floral water; The finished product of the antipruritic floral water prepared in this embodiment was inspected: it had no irritating odor and had a fresh smell.

[0017] Example 2

[0018] An antipruritic floral water, comprising 8 parts of scutellaria baicalensis leaf extract, 2 parts of magnolia officinalis flower essential oil, 2 parts of menthol, 9 parts of propolis, 2 parts of lauric acid monoglyceride, 45 parts of ethanol and 45 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of Scutellaria scabra were taken, crushed, immersed in deionized water and allowed to stand for 50 minutes, then adjusted to pH 5.8 with NaAc-HAc buffer solution, added with complex enzyme, hydrolyzed for 20 minutes at 50°C, inactivated at 100°C, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 50 minutes at an ultrasonic frequency of 90KHz and a temperature of 38°C, filtered, and the filtrate was dried under reduced pressure at a temperature of 52°C and a vacuum degree of 0.04MPa to obtain a Scutellaria scabra leaf extract; The compound enzyme is prepared by mixing plant hydrolase and non-starch polysaccharide enzyme in a weight ratio of 1:1, wherein the plant hydrolase is food grade with an enzyme activity of 10000u / g; the non-starch polysaccharide enzyme is food grade with an enzyme activity of 20000u / g; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 45°C, and then CO2 is introduced to completely replace the air; (3) The extraction pressure is 25 MPa, the CO2 gas flow rate is 40 Kg / h and maintained for 60 min. After the extraction is completed, an extract is obtained; (4) separating the extract to obtain Magnolia officinalis flower essential oil; The extraction entrainer is 92% vol ethanol, and its dosage is 10% of the weight of Magnolia officinalis flower; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of Cyperus rotundus leaves, Magnolia officinalis flower essential oil and monolaurin, then add ethanol and menthol, add 50% water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 50°C, stir evenly, and cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is an antipruritic floral water; The finished product of the antipruritic floral water prepared in this embodiment was inspected: it had no irritating odor and had a fresh smell.

[0019] Example 3

[0020] An antipruritic floral water, comprising 6 parts of scutellaria baicalensis leaf extract, 1 part of magnolia officinalis flower essential oil, 1 part of menthol, 8 parts of propolis, 1 part of glyceryl monostearate, 40 parts of ethanol and 30 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of Scutellaria scabra were taken, crushed, immersed in deionized water and allowed to stand for 35 minutes, then adjusted to pH 6.2 with NaAc-HAc buffer solution, and then added with complex enzyme, hydrolyzed for 20 minutes at 45°C, inactivated at 100°C, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 90 minutes at an ultrasonic frequency of 120KHz and a temperature of 35°C, filtered, and the filtrate was dried under reduced pressure at a temperature of 45°C and a vacuum degree of 0.02MPa to obtain a Scutellaria scabra leaf extract; The compound enzyme is prepared by mixing plant hydrolase and non-starch polysaccharide enzyme in a weight ratio of 1:2, wherein the plant hydrolase is food grade with an enzyme activity of 10000u / g; the non-starch polysaccharide enzyme is food grade with an enzyme activity of 10000u / g; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 40°C, and then CO2 is introduced to completely replace the air; (3) The extraction pressure is 20 MPa, the CO2 gas flow rate is 30 Kg / h and maintained for 60 min. After the extraction is completed, an extract is obtained; (4) separating the extract to obtain Magnolia officinalis flower essential oil; The extraction entrainer is 90% vol ethanol, and its dosage is 15% of the weight of Magnolia officinalis flower; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and glyceryl monostearate, then add ethanol and menthol, add 50% of water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, and heat to 50℃~60℃. Stir evenly and cool to room temperature to obtain phase B. Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is an antipruritic floral water; The finished product of the antipruritic floral water prepared in this embodiment was inspected: it had no irritating odor and had a fresh smell.

[0021] Comparative Example 1

[0022] An antipruritic floral water, comprising 10 parts of scutellaria baicalensis leaf extract, 1 part of magnolia officinalis flower essential oil, 3 parts of menthol, 8 parts of propolis, 3 parts of glyceryl monostearate, 40 parts of ethanol and 50 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of Scutellaria scabra were taken, crushed, immersed in deionized water and allowed to stand for 45 minutes, then adjusted to pH 6.1 with NaAc-HAc buffer solution, and then added with plant hydrolase, hydrolyzed for 25 minutes at 48°C, inactivated at 100°C, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 75 minutes at an ultrasonic frequency of 110KHz and a temperature of 40°C, filtered, and the filtrate was dried under reduced pressure at a temperature of 50°C and a vacuum degree of 0.03MPa to obtain a Scutellaria scabra leaf extract; Among them, the plant hydrolase is food grade, with an enzyme activity of 10000u / g; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 52°C, and then CO2 is introduced to completely replace the air; (3) The extraction pressure is 25 MPa, the CO2 gas flow rate is 45 kg / h and maintained for 60 min. After the extraction is completed, an extract is obtained; (4) separating the extract to obtain Magnolia officinalis flower essential oil; The extraction entrainer is 95% vol ethanol, and its dosage is 12.5% ​​of the weight of Magnolia officinalis flower; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and glyceryl monostearate, then add ethanol and menthol, add 50% of water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 56°C, stir evenly, and cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is antipruritic floral water.

[0023] Comparative Example 2

[0024] An antipruritic floral water, comprising 10 parts of scutellaria baicalensis leaf extract, 1 part of magnolia officinalis flower essential oil, 3 parts of menthol, 8 parts of propolis, 3 parts of glyceryl monostearate, 40 parts of ethanol and 50 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of Scutellaria scabra were taken, crushed, immersed in deionized water and allowed to stand for 45 minutes, then adjusted to pH 6.1 with NaAc-HAc buffer solution, and then non-starch polysaccharide enzyme was added, and enzymolysis was performed for 25 minutes at a temperature of 48°C, inactivated at 100°C, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 75 minutes at an ultrasonic frequency of 110KHz and a temperature of 40°C, filtered, and the filtrate was dried under reduced pressure at a temperature of 50°C and a vacuum degree of 0.03MPa to obtain a Scutellaria scabra leaf extract; Among them, the non-starch polysaccharide enzyme is food grade, with an enzyme activity of 15000u / g; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 52°C, and then CO2 is introduced to completely replace the air; (3) The extraction pressure is 25 MPa, the CO2 gas flow rate is 45 kg / h and maintained for 60 min. After the extraction is completed, an extract is obtained; (4) separating the extract to obtain Magnolia officinalis flower essential oil; The extraction entrainer is 95% vol ethanol, and its dosage is 12.5% ​​of the weight of Magnolia officinalis flower; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and glyceryl monostearate, then add ethanol and menthol, add 50% of water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 56°C, stir evenly, and cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is antipruritic floral water.

[0025] Comparative Example 3

[0026] An antipruritic floral water, comprising 10 parts of scutellaria baicalensis leaf extract, 1 part of magnolia officinalis flower essential oil, 3 parts of menthol, 8 parts of propolis, 3 parts of glyceryl monostearate, 40 parts of ethanol and 50 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of the Chinese yew are crushed, immersed in deionized water and allowed to stand for 45 minutes, then adjusted to pH 6.1 with a NaAc-HAc buffer solution, and then subjected to ultrasonic countercurrent extraction for 75 minutes at an ultrasonic frequency of 110 KHz and a temperature of 40° C., filtered, and the filtrate is dried under reduced pressure at a temperature of 50° C. and a vacuum degree of 0.03 MPa to obtain a Chinese yew leaf extract; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 52°C, and then CO2 is introduced to completely replace the air; (3) The extraction pressure is 25 MPa, the CO2 gas flow rate is 45 kg / h and maintained for 60 min. After the extraction is completed, an extract is obtained; (4) separating the extract to obtain Magnolia officinalis flower essential oil; The extraction entrainer is 95% vol ethanol, and its dosage is 12.5% ​​of the weight of Magnolia officinalis flower; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and glyceryl monostearate, then add ethanol and menthol, add 50% of water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 56°C, stir evenly, and cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is antipruritic floral water.

[0027] Comparative Example 4

[0028] An antipruritic floral water, comprising 10 parts of safflower leaf extract, 3 parts of menthol, 8 parts of propolis, 3 parts of glyceryl monostearate, 40 parts of ethanol and 50 parts of water; The preparation method of the extract of the leaves of the Rhizoma Cyperi var. The dried leaves of Scutellaria scabra were taken, crushed, immersed in deionized water and allowed to stand for 45 minutes, then adjusted to pH 6.1 with NaAc-HAc buffer solution, and then added with complex enzyme, hydrolyzed for 25 minutes at 48°C, inactivated at 100°C, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 75 minutes at an ultrasonic frequency of 110KHz and a temperature of 40°C, filtered, and the filtrate was dried under reduced pressure at a temperature of 50°C and a vacuum degree of 0.03MPa to obtain a Scutellaria scabra leaf extract; The compound enzyme is prepared by mixing plant hydrolase and non-starch polysaccharide enzyme in a weight ratio of 2:1, wherein the plant hydrolase is food grade with an enzyme activity of 10000u / g; the non-starch polysaccharide enzyme is food grade with an enzyme activity of 15000u / g; The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the safflower leaf and glyceryl monostearate, then add ethanol and menthol, add 50% water while stirring, stir evenly to obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 56°C, stir evenly, and cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is antipruritic floral water.

[0029] Test Example 1

[0030] To test the irritation of floral water, a skin patch test was conducted; The test method is: 30 healthy volunteers were selected, and the floral water of Examples 1 to 3 of the present invention and Comparative Examples 1 to 4 were used to conduct a 48-hour closed patch test on the back skin of the 30 volunteers. All results showed no irritation, indicating that the antipruritic floral water of the present invention is safe and non-irritating.

[0031] Test Example 2

[0032] Test samples: Examples 1 to 3 of the present invention, Comparative Examples 1 to 4, and commercially available floral water (Liushen brand, main ingredients of which are mint, borneol, honeysuckle, artificial bezoar, snake gall, and artificial musk); Subjects: 150 volunteers aged 15 to 55 years; Test method: The test subjects were randomly divided into 8 groups, each with 15 subjects, and used Examples 1 to 3, Comparative Examples 1 to 4, and commercially available floral water, respectively. Used once a day in the morning and evening, sprayed on the exposed skin of the hands, legs, etc., for one week, and scored the mosquito repellent effect, swelling and itching effect, irritation, and cooling feeling. 5 points was the highest score, and 3 points or less was a poor effect. The average score was taken, and the results are shown in Table 1 below.

[0033] Table 1 Human test effect rating: sample Mosquito repellent effect Anti-swelling and anti-itching effect Non-irritating Cooling sensation Example 1 4.8 4.9 4.9 4.9 Example 2 4.7 4.8 4.7 4.8 Example 3 4.6 4.8 4.7 4.8 Comparative Example 1 4.5 4.3 4.4 4.5 Comparative Example 2 4.5 4.2 4.3 4.5 Comparative Example 3 4.4 3.9 4.2 4.3 Comparative Example 4 4.3 3.5 4.2 4.3 Commercially available floral water 4.2 3.8 4.3 4.7 As shown in Table 1, the floral water of Examples 1 to 3 of the present invention has obvious mosquito repelling effect, significant swelling and antipruritic effect, and the floral water of the present invention is non-irritating to the skin and has a cool feeling after use. In Comparative Examples 1 to 4, the mosquito repelling effect of the commercial floral water is slightly worse than that of Examples 1 to 3 of the present invention, and the swelling and antipruritic effect is significantly lower than that of Examples 1 to 3 of the present invention, indicating that the floral water of the present invention achieves mosquito repelling and antipruritic effect through synergistic effect among the various components, and improves the comfort of use.

[0034] The above embodiments are merely preferred implementations of the present invention. Any simple modification, amendment and substitution of the above embodiments based on the technical essence of the present invention are within the scope of the technical solution of the present invention.

Claims

1. Use of a safflower leaf extract in the preparation of antipruritic floral water, characterized in that: The antipruritic floral water is composed of 6 to 10 parts of safflower leaf extract, 1 to 3 parts of magnolia officinalis essential oil, 1 to 3 parts of menthol, 8 to 12 parts of propolis, 1 to 3 parts of cosolvent, 40 to 60 parts of ethanol and 30 to 50 parts of water; The preparation method of the extract of the leaves of the safflower oil plant comprises the following steps: The dried leaves of the Chinese yew are taken, crushed, immersed in deionized water and allowed to stand for 30 to 50 minutes, then adjusted to a pH of 5.8 to 6.2 with a NaAc-HAc buffer solution, and then added with a composite enzyme, and hydrolyzed for 20 to 30 minutes at a temperature of 45 to 50 degrees Celsius, inactivated at 100 degrees Celsius, filtered, and the residue was subjected to ultrasonic countercurrent extraction for 40 to 90 minutes at an ultrasonic frequency of 80 kHz to 120 kHz and a temperature of 35 to 45 degrees Celsius, filtered, and the filtrate was dried under reduced pressure to obtain a Chinese yew leaf extract; The preparation method of the magnolia officinalis flower essential oil comprises the following steps: (1) Take dried Magnolia officinalis flowers, crush them, and perform supercritical CO2 extraction; (2) The extraction temperature reaches 40°C to 60°C, and then CO2 is introduced to completely replace the air; (3) Control the extraction pressure to 20 MPa to 30 MPa and the CO2 gas flow rate to 30 kg / h to 50 kg / h, and maintain for 60 minutes. After the extraction is completed, an extract is obtained; (4) Separating the extract to obtain Magnolia officinalis flower essential oil.

2. The use of the extract of the leaves of the Rhizoma Cyperi according to claim 1 in the preparation of antipruritic floral water, characterized in that: The preparation method of the antipruritic floral water is as follows: Accurately weigh the extract of the leaves of the safflower, the essential oil of the magnolia officinalis flower and the cosolvent, then add ethanol and menthol, add 50% of water while stirring, stir evenly, and obtain phase A; Accurately weigh propolis, add the remaining 50% of water, heat to 50℃~60℃, stir evenly, cool to room temperature to obtain phase B; Mix phase A and phase B and stir evenly, let stand, filter through a filter membrane, and the filtrate is antipruritic floral water.

3. The use of the extract of the leaves of the Rhizoma Cyperi according to claim 1 in the preparation of antipruritic floral water, characterized in that: In the preparation method of the extract of the leaves of the safflower, the complex enzyme is prepared by mixing plant hydrolases and non-starch polysaccharide enzymes in a weight ratio of 1-2:1-2; Among them, the plant hydrolase is food grade with an enzyme activity of 10,000u / g; the non-starch polysaccharide enzyme is food grade with an enzyme activity of 10,000u / g to 20,000u / g.

4. The use of the extract of the leaves of the Rhizoma Cyperi according to claim 1 in the preparation of antipruritic floral water, characterized in that: In the preparation method of the extract of the leaves of the safflower, the conditions for reduced pressure drying are: temperature 45° C. to 55° C., and vacuum degree 0.02 MPa to 0.04 MPa.

5. Use of the extract of the leaves of the Rhizoma Cyperi according to claim 1 in the preparation of antipruritic floral water, characterized in that: In the preparation method of magnolia flower essential oil, the extraction entrainer is 90%vol-96%vol ethanol, and its usage is 10%-15% of the weight of magnolia flower.

6. Use of the extract of the leaves of the Rhizoma Cyperi according to claim 1 in the preparation of antipruritic floral water, characterized in that: The cosolvent is one of glyceryl monostearate or glyceryl monolaurate.