Application of traditional Chinese medicine composition for strengthening body resistance, eliminating pathogenic factors and treating HPV infection

Abstract

The invention discloses application of a traditional Chinese medicine composition for strengthening body resistance, eliminating evil and treating HPV infection, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition comprises the following raw materials: 40-50 parts of astragalus membranaceus, 40-50 parts of codonopsis pilosula slices, 40-50 parts of rhizoma smilacis glabrae, 25-45 parts of rehmannia, 10-20 parts of fructus cnidii and 10-20 parts of radix sophorae flavescentis. The traditional Chinese medicine composition is mainly applied in the form of a traditional Chinese medicine external preparation, and can be used for treating one of low-risk HPV infection, high-risk HPV infection and mixed HPV infection and various diseases caused by HPV infection. The traditional Chinese medicines such as astragalus membranaceus, codonopsis pilosula and the like for tonifying healthy qi are matched with the traditional Chinese medicines such as rhizoma smilacis glabrae, fructus cnidii, sophora flavescens, rehmannia glutinosa and the like for clearing away heat and toxic materials and eliminating evil, so that the traditional Chinese medicine composition can be exactly used for the symptoms of qi deficiency and exogenous infection such as HPV (human papillomavirus) infection or qi and blood deficiency caused by interior excess and heat accumulation, and the principle of strengthening healthy qi and eliminating evil is adopted, so that pathogenic factors are attacked without damaging healthy qi, the curative effect can be improved, and disease relapse can be inhibited; and side effects are reduced.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an application of a traditional Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection. Background Art

[0002] HPV, also known as human papillomavirus, is a relatively small double-stranded DNA virus known to date. It is mainly divided into high-risk and low-risk types according to its carcinogenicity. If high-risk HPV infection persists for a long time, it may cause abnormal cell proliferation on the surface of the cervix, leading to cervical intraepithelial neoplasia and even cervical cancer. Cervical cancer is a malignant tumor that is common in women and poses a serious threat to women's health. Currently, more than 95% of cervical cancers in the world are caused by HPV infection.

[0003] At present, there is no particularly good specific medicine for the treatment of HPV infection and its complications, including cervical cancer. Western medicine, physical therapy and surgical treatment are effective in treating HPV infection in clinical practice, but there is a certain probability of recurrence, and the course of treatment is long and the side effects are large. In recent years, the application scope of traditional Chinese medicine has become wider and wider. For HPV infection, traditional Chinese medicine believes that the main cause is deficiency of the root and excess of the superficial. Internally, it is the imbalance of internal organs and the lack of body qi, and externally, it is the invasion of dampness and toxicity. Through oral and external Chinese medicine and other methods of treatment, the virus conversion rate and long-term efficacy are improved, and the recurrence rate is reduced. However, there are still defects such as the bitterness of Chinese medicine, which hurts the spleen and stomach, and the slow effect. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine composition for treating HPV infection by strengthening the body's resistance and eliminating pathogens, so as to solve the problems of slow effect, high recurrence rate and significant side effects in treating HPV infection.

[0005] The purpose of the present invention can be achieved by the following technical solutions:

[0006] The present invention provides an application of a traditional Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 40-50 parts of astragalus, 40-50 parts of codonopsis pilosula, 40-50 parts of smilax glabra, 25-45 parts of rehmannia root, 10-20 parts of cnidium monnieri and 10-20 parts of sophora flavescens.

[0007] Preferably, the Chinese medicine composition comprises the following raw materials in parts by weight: 42-48 parts of Astragalus, 42-48 parts of Codonopsis pilosula, 43-46 parts of Smilax glabra, 30-35 parts of Rehmannia root, 15-20 parts of Cnidium monnieri and 12-18 parts of Sophora flavescens.

[0008] Preferably, the Chinese medicine composition comprises the following raw materials in parts by weight: 45 parts of Astragalus, 45 parts of Codonopsis pilosula, 45 parts of Smilax glabra, 30 parts of Rehmannia root, 20 parts of Cnidium monnieri and 15 parts of Sophora flavescens.

[0009] Traditional Chinese medicine believes that the pathogenesis of HPV infection and complications caused by HPV infection lies in the body's insufficiency of vital energy and its inability to resist external pathogens. Damp-heat and toxic pathogens take the opportunity to accumulate in the vulva and genitals, and the stalemate between the vital energy and the evil eventually leads to the deficiency of vital energy and the excess of evil, which progresses to cancer. The most common symptoms of the infected are damp-heat and spleen deficiency and dampness. By adopting the above technical scheme, both Astragalus and Codonopsis have the effect of replenishing vital energy, among which Astragalus can both nourish the spleen and strengthen the lungs; Codonopsis can strengthen the spleen and replenish qi. Although it has no power to strengthen the surface, it can replenish qi and produce body fluid. Modern pharmacology also shows that the astragalus polysaccharides, folic acid, amino acids and other compounds contained in Astragalus, as well as the alkaloids, amino acids and polysaccharides contained in Codonopsis have the effects of enhancing the body's immunity, anti-oxidation and delaying aging. The combination of the two can replenish vital energy to improve the immunity-enhancing effect.

[0010] The main function of Smilax glabra is to clear away heat and detoxify. By removing dampness, it can be combined with tonic herbs such as Astragalus and Codonopsis to enhance the tonic effect of the medicine, and it does not leave evil spirits. As an antidote, Smilax glabra is mild in nature and will not cause excessive coldness and excessive heat clearing, which will damage the positive energy and block the flow of qi, blood and body fluids, thereby aggravating the condition. In addition, while Smilax glabra detoxifies, it can be used together with detoxifiers such as Cnidium monnieri and Sophora flavescens to enhance the effect of removing dampness and detoxification. Cnidium monnieri and Sophora flavescens can be used together to improve the patient's vaginal microecology, and have the effects of drying heat and stopping leukorrhea, killing insects and relieving itching, clearing heat and detoxifying, which just fits the principle of clearing heat and drying dampness in the treatment of HPV infection.

[0011] In addition, the formula also contains Rehmannia root, which can nourish yin and blood, nourish the liver and benefit the kidney. Blood is the mother of Qi, and when Qi is deficient for a long time, the blood is also deficient. When Rehmannia root is combined with Astragalus and Codonopsis pilosula, it can enhance the effect of the composition in replenishing the vital energy, nourishing yin and clearing away heat, and can also provide the effect of nourishing blood and promoting body fluid. At the same time, Rehmannia root is combined with detoxifying drugs such as Smilax glabra, Cnidium monnieri and Sophora flavescens, which can also improve the effect of the composition in raising the clear and lowering the turbid, clearing away heat and removing dampness, and improving the effect of the composition in expelling evil.

[0012] The sophora flavescens of the present invention is a cold Chinese medicine, which has a strong effect of removing damp-heat pathogens, and can have a strong effect on treating HPV infection. At the same time, it is assisted by warm Chinese medicines such as Cnidium monnieri and Astragalus membranaceus and mild Chinese medicines such as Smilax glabra, which can disperse the damp-cold pathogens in a gentle manner, and will not cause the cold medicine to damage the vital energy, bringing large side effects. If only warm Chinese medicines are used, it will only advocate the damp-heat pathogens, consume yin and hurt body fluid, and the warm-cold composition interacts with each other to achieve the harmony of yin and yang. In addition, the present invention adopts the compatibility of the Chinese medicines for replenishing vital energy such as Astragalus membranaceus and Codonopsis pilosula and the Chinese medicines for clearing away heat and toxic substances such as Smilax glabra, Cnidium monnieri, Sophora flavescens and Rehmannia glutinosa, which can be used for HPV infection and other symptoms of qi deficiency exogenous infection or internal heat accumulation and qi and blood deficiency, etc., with the principle of replenishing qi and removing pathogens, so that the pathogens are attacked without damaging the vital energy, the efficacy of the Chinese medicine composition is improved, and the recurrence of symptoms is effectively suppressed.

[0013] Preferably, the Chinese medicine composition further comprises 15 to 25 parts by weight of Cimicifuga heracleifolia.

[0014] More preferably, the Chinese medicine composition further comprises 18 to 21 parts by weight of Cimicifuga heracleifolia.

[0015] More preferably, the Chinese medicine composition further comprises 20 parts by weight of Cimicifuga heracleifolia.

[0016] By adopting the above technical scheme, Cimicifuga has the effects of clearing away heat and detoxifying, and raising Yang Qi. For some patients infected with HPV and who have not turned negative for a long time, adding Cimicifuga can more effectively regulate the distribution and flow of Yang Qi in the body, thereby improving the symptoms of Qi deficiency and sinking. The effect of replenishing Qi and blood can be enhanced by cooperating with the tonic and strengthening medicinal materials in the Chinese medicine composition. It can be used to improve the flow of clear Qi in the body, promote blood circulation, improve Qi and blood stasis, help the circulation of Yang Qi, and restore normal physiological functions by cooperating with other dampness-clearing, heat-clearing and detoxifying medicinal materials. In addition, the heat-clearing and detoxifying effects of Cimicifuga can also help remove heat and toxins in the body, further helping long-term infected people to adjust their internal balance and push the evil Qi out.

[0017] Preferably, the Chinese medicine composition is used in the form of a Chinese medicine external preparation.

[0018] Preferably, the dosage form of the Chinese medicine external preparation includes one of a decoction, a gel and a suppository.

[0019] By adopting the above technical scheme, the Chinese medicine composition of the present invention is mainly applied in the form of a Chinese medicine external preparation, and the components of the Chinese medicine composition are directly applied to the local part of the cervix. By retaining the drug in the vagina and continuously maintaining the concentration of the local drug, the therapeutic effect can be enhanced, the development of the virus can be inhibited, the inflammatory response of the infected area can be reduced, and the repair of skin tissue can be promoted, thereby accelerating the healing process of the diseased area while strengthening the body and eliminating pathogens.

[0020] Preferably, the Chinese medicine external preparation is prepared according to the following method:

[0021] S1. Weigh the corresponding weight portions of the raw materials of the Chinese medicine composition and soak them in water for 20 to 30 minutes;

[0022] S2. The soaked raw material of the Chinese medicine composition is decocted twice, wherein the first decoction time is 20 to 25 min, the second decoction time is 15 to 20 min, and the decoction water amount is 7 to 12 times the total mass of the raw material;

[0023] S3. The filtrates obtained from the two decoctions are mixed, concentrated by distillation, and molded to obtain a Chinese medicine external preparation.

[0024] Preferably, the raw materials of the Chinese medicine composition are Chinese herbal medicine slices.

[0025] By adopting the above technical scheme, the Chinese herbal medicine slices are slices of medicinal materials that have been pre-treated, which can ensure the consistency and stability of the medicinal efficacy of the medicinal materials, and can also release the effective ingredients more quickly during the decoction process; and the Chinese herbal external preparation of the present invention adopts a concentrated decoction method for decoction, which can increase the concentration of the medicinal solution, stabilize the properties of the medicinal solution, and enable the effective ingredients in the medicinal materials to be more fully dissolved, which can better help the skin absorb when used externally, thereby improving the therapeutic effect.

[0026] Preferably, the Chinese medicine composition is used for one of low-risk HPV infection, high-risk HPV infection and mixed HPV infection, and one of chronic cervicitis, cervical precancerous lesions, wart-like lesions and condyloma acuminatum caused by HPV infection.

[0027] Beneficial effects of the present invention:

[0028] 1. The present invention is mainly used for various types of HPV infection and complications caused by infection. In the Chinese medicine composition, Astragalus and Codonopsis are used in combination as tonic and strengthening medicinal materials, which play the role of tonic and strengthening the body's immunity. Smilax glabra, Cnidium monnieri and Sophora flavescens are used in combination as dehumidifying and expelling pathogenic factors, which play the role of clearing away heat, detoxifying and removing dampness. At the same time, it is assisted by Rehmannia root to replenish blood and produce body fluid, raise clearness and lower turbidity. The mutual compatibility of various compositions can warm and harmonize the cold, with the principle of replenishing qi and expelling pathogenic factors, strengthening the body's health and expelling pathogenic factors, so that the pathogenic factors are attacked without damaging the healthy qi, thereby improving the treatment effect, reducing side effects, and effectively inhibiting the recurrence of symptoms.

[0029] 2. Cimicifuga can also be added to the Chinese medicine composition of the present invention to improve qi deficiency and sinking, regulate the distribution and flow of yang qi in the body, improve the circulation of clear qi and qi and blood stasis in the body while replenishing qi and blood, and assist in clearing heat and toxins in the body. It can effectively help long-term infected people regulate the balance of yin and yang in the body, promote the excretion of evil qi, and achieve a healing effect. DETAILED DESCRIPTION

[0030] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Example 1, a Chinese medicine composition for strengthening the body and eliminating evil to treat HPV infection, using a Chinese medicine external preparation decoction for HPV infection and its complications, wherein the Chinese medicine composition formula used is: 45g of Astragalus, 45g of Codonopsis pilosula, 45g of Smilax glabra, 30g of Rehmannia root, 20g of Cnidium monnieri, and 15g of Sophora flavescens. The raw materials of the Chinese medicine composition in the formula are all Chinese medicine pieces.

[0032] The preparation method of the Chinese medicine external preparation decoction comprises the following steps:

[0033] S1. According to the above-mentioned Chinese medicine composition, weigh the corresponding Chinese medicine pieces and soak them in water for 25 minutes;

[0034] S2. The soaked raw material of the Chinese medicine composition was decocted twice, wherein the first decoction time was 25min, the second decoction time was 20min, and the decoction water amount was 8 times the total mass of the raw material;

[0035] S3. The filtrates obtained from the two decoctions are mixed, distilled and concentrated to obtain a Chinese medicine decoction for external use.

[0036] Example 2, an application of a traditional Chinese medicine composition for strengthening the body and eliminating evil to treat HPV infection, which is different from Example 1 only in that the traditional Chinese medicine composition used is composed of: 42g of Astragalus, 48g of Codonopsis pilosula, 43g of Smilax glabra, 30g of Rehmannia root, 20g of Cnidium monnieri, and 20g of Sophora flavescens.

[0037] Example 3, an application of a traditional Chinese medicine composition for strengthening the body and eliminating evil to treat HPV infection, which is different from Example 1 only in that the traditional Chinese medicine composition used is composed of: 48g of Astragalus, 42g of Codonopsis pilosula, 40g of Smilax glabra, 35g of Rehmannia root, 15g of Cnidium monnieri, and 12g of Sophora flavescens.

[0038] Example 4, an application of a traditional Chinese medicine composition for strengthening the body and eliminating evil to treat HPV infection, which is different from Example 1 only in that the traditional Chinese medicine composition used is composed of: 50g of Astragalus, 42g of Codonopsis pilosula, 48g of Smilax glabra, 45g of Rehmannia root, 10g of Cnidium monnieri, and 18g of Sophora flavescens.

[0039] Example 5, an application of a traditional Chinese medicine composition for strengthening the body and eliminating evil to treat HPV infection, which is different from Example 1 only in that the traditional Chinese medicine composition used is composed of: 40g of Astragalus, 50g of Codonopsis pilosula, 50g of Smilax glabra, 25g of Rehmannia root, 20g of Cnidium monnieri, and 10g of Sophora flavescens.

[0040] Example 6, an application of a traditional Chinese medicine composition for strengthening the body and eliminating pathogens to treat HPV infection, which is different from Example 1 only in that the traditional Chinese medicine composition used is composed of: 45g of Astragalus, 45g of Codonopsis pilosula, 45g of Smilax glabra, 30g of Rehmannia glutinosa, 20g of Cnidium monnieri, 15g of Sophora flavescens, and 20g of Cimicifuga heracleifolia.

[0041] Example 7, an application of a traditional Chinese medicine composition for strengthening the body and eliminating pathogens to treat HPV infection, which is different from Example 6 only in that the traditional Chinese medicine composition used is composed of: 45g of Astragalus, 45g of Codonopsis pilosula, 45g of Smilax glabra, 30g of Rehmannia glutinosa, 20g of Cnidium monnieri, 15g of Sophora flavescens, and 18g of Cimicifuga heracleifolia.

[0042] Example 8, an application of a traditional Chinese medicine composition for strengthening the body and eliminating pathogens to treat HPV infection, which is different from Example 6 only in that the traditional Chinese medicine composition used is composed of: 45g of Astragalus, 45g of Codonopsis pilosula, 45g of Smilax glabra, 30g of Rehmannia root, 20g of Cnidium monnieri, 16g of Sophora flavescens, and 15g of Cimicifuga heracleifolia.

[0043] Example 9, an application of a traditional Chinese medicine composition for strengthening the body and eliminating pathogens to treat HPV infection, which is different from Example 6 only in that the traditional Chinese medicine composition used is composed of: 45g of Astragalus, 45g of Codonopsis pilosula, 45g of Smilax glabra, 30g of Rehmannia glutinosa, 20g of Cnidium monnieri, 12g of Sophora flavescens, and 24g of Cimicifuga heracleifolia.

[0044] Clinical trials:

[0045] 1. Sample population: 30 HPV-infected patients admitted from September 2018 to May 2024, females aged 30 to 66 years old.

[0046] 2. Experimental method: The sample population was randomly divided into two groups, 15 people in each group, of which the control group was treated with interferon; the experimental group was treated with the Chinese medicine external preparation made from the Chinese medicine composition of the present invention, with a dosage of 80 mL each time, once a day, divided into three courses of treatment, each course of treatment lasting 3 weeks.

[0047] 3. Treatment results: After the treatment course, a reexamination was conducted and the results were compared. Recovery means that the HPV reexamination was negative and there was no recurrence after three months of stopping the medication; improvement means that the clinical symptoms were significantly alleviated; ineffectiveness means that the clinical symptoms did not improve significantly or worsened, and the HPV reexamination result was positive. In addition, statistics were collected to see if there were any adverse reactions during the medication period.

[0048] The above test results are shown in Table 1:

[0049] Table 1 Statistical results of clinical trials

[0050] Group Number of recovered people Number of people who have improved Invalid number of people Adverse Reactions Effectiveness / % Experimental Group 11 4 0 0 100 Control group 2 5 8 3 46.7

[0051] It can be seen from the clinical trials and the test results in Table 1 that the number of cured patients and the effective rate of the treatment with the present invention are significantly higher than those of the control group (P value < 0.05), and no side effects were found during the treatment process of the present invention, which shows that the Chinese herbal external preparation prepared by the present invention plays an effective role in the treatment of HPV infection, has no tendency to relapse and no side effects, and can be safely used to treat various types of HPV infections and complications caused by the infection.

[0052] Application Example 1: Wei, 67 years old, tested positive for HPV in November 2022, and was positive for HPV high-risk type 52. Western medicine treatment had no obvious effect. He started the first course of Chinese medicine in February 2023. The Chinese medicine external preparation prepared in Example 1 was used for treatment, with a dosage of 80 mL each time, once a day. After three courses of Chinese medicine treatment, he was re-examined in April 2024, and the HPV test was negative, and there was no recurrence.

[0053] Application Example 2: Mr. Du, 60 years old, tested positive for HPV in March 2022, and was positive for HPV high-risk types 16 and 31. After Western medicine treatment, he was tested positive for HPV high-risk type 16 in June 2022. He was then transferred to Chinese medicine treatment and the Chinese medicine external preparation prepared in Example 1 was used for treatment. The dosage was 200 mL each time, once a day. After the course of treatment, he was re-examined in April 2023, and the HPV test was negative, and there was no recurrence.

[0054] Application Example 3: Guan, 59 years old, underwent a hysterectomy in 2017 and was infected with HPV in 2020. In October 2020, the examination showed that HPV high-risk types 52 and 59 were positive. In October 2021, the examination showed that HPV high-risk types 16, 51, 52, 59 were positive and low-risk types 6 and 42 were positive for mixed infection. After Western medicine treatment, in March 2022, the examination showed that HPV high-risk type 16 was positive and low-risk types 6 and 42 were positive for mixed infection. In the same month, he was transferred to traditional Chinese medicine treatment, and the Chinese medicine external preparation prepared in Example 1 was used for treatment, with a dosage of 80 mL each time, once a day. After three courses of traditional Chinese medicine treatment, he was re-examined in August 2022, and the HPV test was negative. After that, he had sexual life and was tested positive for HPV high-risk type 42 in December 2022. He continued treatment and was re-examined in July 2023, and the HPV test was negative. He was re-examined in February 2024, and the HPV test was negative, with no recurrence.

[0055] Application Example 4, Yang, 31 years old, tested positive for HPV high-risk type 18 in September 2018. Until December 2022, he received Western medicine treatment, using interferon and Baofukang suppository for treatment. The reexamination result was still positive for HPV high-risk types 18 and 59. He was transferred to traditional Chinese medicine treatment in May 2023, using the Chinese medicine external preparation prepared in Example 6 for treatment, with a dosage of 80 mL each time, once a day. After three courses of traditional Chinese medicine treatment, he was reexamined in September 2023, and the HPV test was negative. He was reexamined in April 2024, and the HPV test was negative, with no recurrence.

[0056] Application Example 5, Huang, 32 years old, was diagnosed with HPV high-risk types 51, 59, and 66 in August 2021. In March 2022, he was diagnosed with a mixed infection of HPV high-risk types 51, 59, and 66 and low-risk type 43. He received laser surgery in May of the same year. He relapsed in September 2022 and underwent laser surgery again in conjunction with Western medicine treatment, but there was no obvious effect. He was transferred to traditional Chinese medicine treatment in January 2023, using the Chinese medicine external preparation prepared in Example 6 for treatment, with a dosage of 80 mL each time, once a day. After three courses of traditional Chinese medicine treatment, he was reexamined in February 2024, and the HPV test was negative, with no recurrence.

[0057] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0058] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An application of a Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection, characterized in that: The Chinese medicine composition comprises the following raw materials in parts by weight: 40-50 parts of astragalus, 40-50 parts of codonopsis slices, 40-50 parts of smilax glabra, 25-45 parts of rehmannia root, 10-20 parts of cnidium monnieri and 10-20 parts of sophora flavescens.

2. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 1, characterized in that: The Chinese medicine composition comprises the following raw materials in parts by weight: 42-48 parts of astragalus, 42-48 parts of codonopsis slices, 43-46 parts of smilax glabra, 30-35 parts of rehmannia root, 15-20 parts of cnidium monnieri and 12-18 parts of sophora flavescens.

3. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 1, characterized in that: The Chinese medicine composition comprises the following raw materials in parts by weight: 45 parts of astragalus, 45 parts of codonopsis pilosula, 45 parts of smilax glabra, 30 parts of rehmannia root, 20 parts of cnidium monnieri and 15 parts of sophora flavescens.

4. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 1, characterized in that: The traditional Chinese medicine composition further comprises 15 to 25 parts by weight of Cimicifuga heracleifolia.

5. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 1, characterized in that: The Chinese medicine composition is used in the form of a Chinese medicine external preparation.

6. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 5, characterized in that: The dosage form of the traditional Chinese medicine external preparation includes one of a decoction, a gel and a suppository.

7. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 5, characterized in that: The Chinese medicine external preparation is prepared according to the following method: S1. Weigh the corresponding weight portions of the raw materials of the Chinese medicine composition and soak them in water for 20 to 30 minutes; S2. The soaked raw material of the Chinese medicine composition is decocted twice, wherein the first decoction time is 20 to 25 min, the second decoction time is 15 to 20 min, and the decoction water amount is 7 to 12 times the total mass of the raw material; S3. The filtrates obtained from the two decoctions are mixed, concentrated by distillation, and molded to obtain a Chinese medicine external preparation.

8. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 7, characterized in that: The raw materials of the Chinese medicine composition are Chinese medicine pieces.

9. The use of the Chinese medicine composition for strengthening the body's resistance and eliminating pathogens to treat HPV infection according to claim 1, characterized in that: The Chinese medicine composition is used for one of low-risk HPV infection, high-risk HPV infection and mixed HPV infection, and one of chronic cervicitis, cervical precancerous lesions, wart-like lesions and condyloma acuminatum caused by HPV infection.