Phototherapy device

Abstract

The invention discloses a phototherapy device, which comprises a flexible substrate, a water-blocking oxygen layer, a light-emitting layer, a packaging layer and a biocompatible material layer, wherein the flexible substrate, the water-blocking oxygen layer, the light-emitting layer and the packaging layer are sequentially stacked; the biocompatible material layer is arranged on one side, far away from the water-blocking oxygen layer, of the flexible substrate and / or on one side, far away from the light-emitting layer, of the packaging layer; the thickness of the biocompatible material layer is smaller than or equal to a first set value, and the Young modulus of the biocompatible material layer is smaller than or equal to a second set value. According to the embodiment of the invention, the film layer can be prevented from being broken or delaminated in the bending process of the phototherapy device, the bending performance of the phototherapy device is improved, the biocompatibility of the phototherapy device is improved, and adverse reactions such as allergy and poisoning of a user in the phototherapy process are prevented.

Description

Technical Field

[0001] The present invention relates to the technical field of phototherapy, and in particular to a phototherapy device. Background Art

[0002] Organic Light-Emitting Diode (OLED) is a photoelectric device that emits light through carrier injection and recombination. The specific light-emitting process of OLED is that electrons are injected through the cathode and transferred to the light-emitting layer through the electron transport material, holes are injected through the anode and transferred to the light-emitting layer through the hole transport material, and electrons and holes recombine in the light-emitting layer to form excitons, which then de-excite to emit light. OLED light-emitting devices have been widely used due to their many advantages such as flexibility, light weight, uniform light emission, and good light quality.

[0003] Flexible OLEDs are gradually being used in optical medical products, which need to be bent for ease of wear to ensure better treatment effects. However, existing optical medical products have poor bending performance, and are prone to film breakage or shedding, which affects their service life. Summary of the invention

[0004] The present invention provides a phototherapy device, which can avoid film breakage or delamination during the bending process of the phototherapy device, improve the bending performance of the phototherapy device, and at the same time improve the biocompatibility of the phototherapy device to prevent users from experiencing adverse reactions such as allergies and poisoning during the phototherapy process.

[0005] According to one aspect of the present invention, there is provided a phototherapy device, comprising:

[0006] Flexible substrate, water-oxygen barrier layer, luminescent layer, encapsulation layer and biocompatible material layer;

[0007] Wherein, the flexible substrate, the water-blocking oxygen layer, the light-emitting layer and the encapsulation layer are stacked in sequence;

[0008] The biocompatible material layer is arranged on a side of the flexible substrate away from the water-oxygen blocking layer and / or on a side of the encapsulation layer away from the light-emitting layer;

[0009] The thickness of the biocompatible material layer is less than or equal to a first set value, and the Young's modulus of the biocompatible material layer is less than or equal to a second set value.

[0010] Optionally, the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer are determined according to the thickness, Young's modulus and Poisson's ratio of the flexible substrate, the water-oxygen blocking layer, the luminescent layer and the encapsulation layer.

[0011] Optionally, the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer are determined by the following formula:

[0012]

[0013] Among them, the film closest to the bending center is the first film, ν i is the Poisson's ratio of the i-th film, the total thickness of the flexible substrate 10, the water-blocking oxygen layer 20, the luminescent layer 30, the encapsulation layer 40 and the biocompatible material layer 50 is h, and the strain of the bottom surface of the film closest to the bending center when the phototherapy device is bent is ε bot , the height from the bottom to the top of the i-th film is z i , the height from the bottom to the top of the i-1th film is z i-1 , i is an integer greater than or equal to 1, the curvature radius of the bottom surface is R, v i is the Poisson's ratio of the i-th film, Ei is the Young's modulus of the i-th film, ε a is the strain of the plane at a height a from the bottom surface, and a is the distance from the set plane in the water-blocking oxygen layer or the encapsulation layer to the bottom surface.

[0014] Optionally, the first set value is less than or equal to 5 mm, and the second set value is less than or equal to 10 GPa.

[0015] Optionally, the thickness of the biocompatible material layer is smaller than the thickness of the packaging layer, and the sum of the thickness of the flexible substrate and the biocompatible material layer is smaller than the thickness of the packaging layer.

[0016] Optionally, the material used for the biocompatible material layer includes at least one of polyurethane, silicone rubber, polyester fiber, polyvinyl pyrrolidone, polyetheretherketone, parylene, polymethyl methacrylate, polyvinyl alcohol, polylactic acid, polyethylene, natural rubber, collagen, protein fiber and gelatin.

[0017] Optionally, the biocompatible material layer covers the side of the flexible substrate, covers the surface of the flexible substrate away from the water-oxygen blocking layer, covers the side of the water-oxygen blocking layer, covers the side of the encapsulation layer and covers the surface of the encapsulation layer away from the luminescent layer.

[0018] Optionally, the transmittance of the biocompatible material layer in a preset wavelength range is greater than or equal to 80%; wherein the preset wavelength range is the light output wavelength range of the phototherapy device.

[0019] Optionally, the preset wavelength range includes 380nm-1000nm.

[0020] Optionally, when the biocompatible material layer is disposed on a side of the flexible substrate away from the water-oxygen blocking layer, an adhesive layer is disposed between the biocompatible material layer and the flexible substrate;

[0021] When the biocompatible material layer is disposed on a side of the packaging layer away from the light-emitting layer, an adhesive layer is disposed between the biocompatible material layer and the packaging layer.

[0022] In this embodiment, a biocompatible material layer is arranged on a side of the flexible substrate away from the water-blocking oxygen layer and / or a side of the encapsulation layer away from the light-emitting layer, and the thickness of the biocompatible material layer is set to be less than or equal to a first set value, and the Young's modulus of the biocompatible material layer is less than or equal to a second set value, so that when the phototherapy device is bent, the stress on the encapsulation layer and the water-blocking oxygen layer is smaller, thereby preventing the encapsulation layer and the water-blocking oxygen layer from being subjected to excessive stress when the phototherapy device is bent, thereby generating a large strain and causing breakage or delamination, thereby improving the bending performance of the phototherapy device, and the biocompatible layer can provide biocompatibility for the phototherapy device to prevent the user from experiencing adverse reactions such as allergies and poisoning during the phototherapy process.

[0023] It should be understood that the contents described in this section are not intended to identify the key or important features of the embodiments of the present invention, nor are they intended to limit the scope of the present invention. Other features of the present invention will become easily understood through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0025] Figure 1 is a schematic diagram of a phototherapy device provided by an embodiment of the present invention;

[0026] Figure 2 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention;

[0027] Figure 3 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention;

[0028] Figure 4 is a curved schematic diagram of a phototherapy device provided by an embodiment of the present invention;

[0029] Figure 5 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention;

[0030] Figure 6 It is a schematic diagram of another phototherapy device provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0031] In order to enable those skilled in the art to better understand the scheme of the present invention, the technical scheme in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0032] It should be noted that the terms "first", "second", etc. in the specification and claims of the present invention and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged where appropriate, so that the embodiments of the present invention described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0033] An embodiment of the present invention provides a phototherapy device, Figure 1 is a schematic diagram of a phototherapy device provided by an embodiment of the present invention, Figure 2 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention, Figure 3 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention. Figure 1-Figure 3 , the phototherapy device comprises:

[0034] Flexible substrate 10, water-blocking oxygen layer 20, luminescent layer 30, encapsulation layer 40 and biocompatible material layer 50;

[0035] Among them, the flexible substrate 10, the water-blocking oxygen layer 20, the light-emitting layer 30 and the encapsulation layer 40 are stacked in sequence;

[0036] The biocompatible material layer 50 is disposed on a side of the flexible substrate 10 away from the water-blocking oxygen layer 20 and / or on a side of the encapsulation layer 40 away from the light-emitting layer 30;

[0037] The thickness of the biocompatible material layer 50 is less than or equal to a first set value, and the Young's modulus of the biocompatible material layer 50 is less than or equal to a second set value.

[0038] Among them, the main material of the flexible substrate 10 is PI (polyimide), the water-blocking oxygen layer 20 may include at least one material of silicon nitride, silicon oxide and silicon oxynitride, and the light-emitting layer 30 may include an anode, a hole injection layer, a hole transport layer, an electron blocking layer, an organic light-emitting layer, a hole blocking layer, an electron transport layer, an electron injection layer and a cathode. The encapsulation layer 40 may be a thin film encapsulation layer, which includes an inorganic layer and an organic layer arranged in sequence, and the outermost layer of the thin film encapsulation layer is an inorganic layer. Exemplarily, the thin film encapsulation layer may be an inorganic / organic / inorganic three-layer structure. The inorganic layer may include at least one material of silicon nitride, silicon oxide and silicon oxynitride. The organic layer may include acrylic or epoxy resin.

[0039] The biocompatible material layer 50 is used to improve the biocompatibility of the phototherapy device and prevent the user from experiencing adverse reactions such as allergies and poisoning during the phototherapy process. The biocompatible material layer 50 can be set on the light-emitting side of the phototherapy device, or on the non-light-emitting side of the phototherapy device. Figure 1 When the phototherapy device emits light from the flexible substrate 10, a biocompatible material layer 50 can be provided on the side of the flexible substrate 10 away from the water-blocking oxygen layer 20. When the biocompatible material layer 50 is not provided on the side of the encapsulation layer 40 away from the light-emitting layer 30, a tape 70 and a protective film 80 can be provided on the side of the encapsulation layer 40 away from the light-emitting layer 30. The tape 70 can be an OCA optical adhesive or a pressure-sensitive adhesive, and the protective film 80 can be PET, aluminum foil or copper foil, etc. The protective film 80 is used to protect other film layers. Figure 2 When the phototherapy device emits light from the encapsulation layer 40, a biocompatible material layer 50 can be provided on the side of the encapsulation layer 40 away from the light-emitting layer 30. The biocompatible material layer 50 can replace the protective mold to protect other film layers, and no protective mold is required. Figure 3 Alternatively, a biocompatible material layer 50 may be disposed on the side of the flexible substrate 10 away from the water-blocking oxygen layer 20 and on the side of the encapsulation layer 40 away from the light-emitting layer 30 .

[0040] Figure 4 is a curved schematic diagram of a phototherapy device provided by an embodiment of the present invention, with reference to Figure 4 During the bending process of the phototherapy device, the film layers at different positions will be subjected to different stresses. Figure 4 When the phototherapy device is bent in the form of a flexible substrate 10, the flexible substrate 10 will be subjected to compressive stress during the bending process, and the encapsulation layer 40 will be subjected to tensile stress (tensile stress) after bending. When the compressive stress is too large, it will cause the film layer to delaminate, and when the tensile stress is too large, it will cause the film layer to break. Generally, due to the good brittleness of inorganic materials, it is easy to cause the water-blocking oxygen layer 20 to delaminate and the encapsulation layer 40 to break during the bending process. In addition, when the phototherapy device is bent in the form of a flexible substrate 10, the flexible substrate 10 will be subjected to compressive stress during the bending process, and the encapsulation layer 40 will be subjected to tensile stress (tensile stress) after bending. When the compressive stress is too large, it will cause the film layer to delaminate, and when the tensile stress is too large, it will cause the film layer to break. Figure 4When the flexible substrate 10 is bent in the opposite direction, that is, when the encapsulation layer 40 is subjected to compressive stress and the flexible substrate 10 is subjected to tensile stress, the water-blocking oxygen layer 20 is easily broken and the encapsulation layer 40 is easily delaminated.

[0041] In this embodiment, the biocompatible material layer 50 is also used to improve the bending performance of the phototherapy device and avoid the encapsulation layer 40 and the water-blocking oxygen layer 20 from breaking or delaminating. The thickness and Young's modulus of the biocompatible material layer 50 will affect the bending performance of the phototherapy device and the bending stress and strain of each film layer when the phototherapy device is bent. By setting the thickness of the biocompatible material layer 50 to be less than or equal to the first set value and the Young's modulus of the biocompatible material layer 50 to be less than or equal to the second set value, when the phototherapy device is bent, the stress on the encapsulation layer 40 or the water-blocking oxygen layer 20 is smaller, so as to avoid excessive stress on the encapsulation layer 40 and the water-blocking oxygen layer 20 when the phototherapy device is bent, resulting in large strain, resulting in breakage or delamination, thereby improving the bending performance of the phototherapy device.

[0042] In this embodiment, a biocompatible material layer 50 is arranged on a side of the flexible substrate 10 away from the water-blocking oxygen layer 20 and / or a side of the encapsulation layer 40 away from the light-emitting layer 30, and the thickness of the biocompatible material layer 50 is arranged to be less than or equal to a first set value, and the Young's modulus of the biocompatible material layer 50 is less than or equal to a second set value, so that when the phototherapy device is bent, the stress on the encapsulation layer 40 and the water-blocking oxygen layer 20 is small, and when the phototherapy device is bent, the encapsulation layer 40 and the water-blocking oxygen layer 20 are prevented from being subjected to excessive stress, generating large strain, causing breakage or delamination, thereby improving the bending performance of the phototherapy device, and the biocompatible layer 50 can improve the biocompatibility of the phototherapy device, and prevent the user from experiencing adverse reactions such as allergies and poisoning during the phototherapy process.

[0043] Optionally, the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 are determined according to the thickness, Young's modulus and Poisson's ratio of the flexible substrate 10 , the water- and oxygen-blocking layer 20 , the luminescent layer 30 and the encapsulation layer 40 .

[0044] Specifically, a relationship between the strain or stress of each layer and the thickness, Young's modulus and Poisson's ratio of the flexible substrate 10, the water-blocking oxygen layer 20, the luminescent layer 30 and the encapsulation layer 40, and the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 can be established. Since the thickness, Young's modulus and Poisson's ratio of the flexible substrate 10, the water-blocking oxygen layer 20, the luminescent layer 30 and the encapsulation layer 40 are fixed values, the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 can be determined according to the required strain. Exemplarily, the stress or strain corresponding to the water-blocking oxygen layer 20 or the encapsulation layer 40 can be set to be less than a set value, thereby calculating the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50.

[0045] In this embodiment, the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 are determined according to the thickness, Young's modulus and Poisson's ratio of the flexible substrate 10, the water-blocking oxygen layer 20, the light-emitting layer 30 and the encapsulation layer 40, so that the determined thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 are more accurate, so that after the biocompatible material layer 50 is set, the stress on the encapsulation layer 40 and the water-blocking oxygen layer 20 is smaller, thereby preventing the encapsulation layer 40 and the water-blocking oxygen layer 20 from being subjected to excessive stress when the phototherapy device is bent, resulting in large strain and causing breakage or delamination.

[0046] Optionally, the thickness and Young's modulus of the biocompatible material layer 50 are determined according to the following formula:

[0047]

[0048] Among them, the film closest to the bending center is the first film, ν i is the Poisson's ratio of the i-th film, the total thickness of the flexible substrate 10, the water-blocking oxygen layer 20, the luminescent layer 30, the encapsulation layer 40 and the biocompatible material layer 50 is h, and the strain of the bottom surface of the film closest to the bending center when the phototherapy device is bent is ε bot , the height from the bottom to the top of the i-th film is z i , the height from the bottom to the top of the i-1th film is z i-1 , i is an integer greater than or equal to 1, the curvature radius of the bottom surface is R, v i is the Poisson's ratio of the i-th film, Ei is the Young's modulus of the i-th film, ε a is the strain of the plane at a height a from the bottom surface, and a is the distance from the set plane in the water-blocking oxygen layer or the encapsulation layer to the bottom surface.

[0049] Specifically, refer to Figure 4 ,by Figure 4 Taking a film layer as an example, the strain expression of any plane extending along the X-axis and Y-axis is obtained according to the generalized Hooke's law as follows:

[0050]

[0051] Among them, E and ν represent the elastic modulus and Poisson's ratio of the material, ε and σ represent strain and stress, respectively. The subscript x represents the direction along the X-axis, y represents the direction along the Y-axis perpendicular to the paper, and z represents the direction along the Z-axis. z = 0, relative to the length of the film segment along the X-axis, the width of the film segment along the Y-axis can be considered to be infinitely extended and no strain is generated, so ε y =0. Combining the above formula, we can get:

[0052]

[0053] Assuming that the bending strain in the multilayer film is linearly distributed along the thickness direction, the strain at a distance z from the bottom surface in the multilayer film can be expressed as:

[0054]

[0055] The resultant force along the X-axis in the multilayer film is zero, and the following formula can be obtained:

[0056]

[0057] From this, the bottom surface strain formula can be obtained as follows:

[0058]

[0059] According to Formula 4 and Formula 6, the strain at a set plane in the water-blocking oxygen layer 20 or the encapsulation layer 40 can be calculated. According to the strain requirements, as well as the thickness, Young's modulus and Poisson's ratio of the flexible substrate, the water-blocking oxygen layer 20, the light-emitting layer 30 and the encapsulation layer 40, the relationship between the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer can be calculated. According to the relationship, the material of the biocompatible material layer can be selected to determine the Young's modulus, Poisson's ratio and thickness of the biocompatible material layer.

[0060] This embodiment establishes the relationship between the thickness, Young's modulus and Poisson's ratio of each layer and the strain, and determines the thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 according to the required strain and the thickness, Young's modulus and Poisson's ratio of the flexible substrate 10, the water-blocking oxygen layer 20, the light-emitting layer 30 and the encapsulation layer 40, so that the determined thickness, Young's modulus and Poisson's ratio of the biocompatible material layer 50 are more accurate, so that after the biocompatible material layer 50 is set, the strain of the encapsulation layer 40 and the water-blocking oxygen layer 20 is small, thereby avoiding excessive strain of the encapsulation layer 40 and the water-blocking oxygen layer 20 when the phototherapy device is bent, resulting in breakage or delamination.

[0061] Optional, ε a The absolute value of is less than or equal to the third set value, that is, the strain of the set plane in the encapsulation layer 40 or the water-blocking oxygen layer 20 is less than the third set value, and the strain of the encapsulation layer 40 or the water-blocking oxygen layer 20 is small, avoiding fracture or delamination. Exemplarily, the third set value is 0. Optionally, the first set value is less than or equal to 5 mm, and can be 5 mm, 4 mm, 3 mm, 2 mm, 1 mm, and the second set value is less than or equal to 10 GPa, and can be 10 GPa, 9 GPa, 8 GPa, 7 GPa, 5 GPa, 3 GPa, 2 GPa, 1 GPa.

[0062] This arrangement ensures that when the phototherapy device is bent, the strain of the packaging layer 40 or the water-blocking oxygen layer 20 is small, thereby preventing the packaging layer 40 and the water-blocking oxygen layer 20 from being broken or delaminated due to excessive strain.

[0063] Optionally, the thickness of the biocompatible material layer 50 is less than the thickness of the encapsulation layer 40 ; the sum of the thickness of the flexible substrate 10 and the biocompatible material layer 50 is less than the thickness of the encapsulation layer 40 .

[0064] Specifically, during the bending process of the multi-layer film, the film layer with smaller strain will be close to the film layer with larger thickness. By setting the thickness of the biocompatible material layer 50 to be smaller than the thickness of the encapsulation layer, the thickness of the flexible substrate 10 and the biocompatible material layer 50 is smaller than the thickness of the encapsulation layer 40, so that the film layer with smaller strain is closer to the encapsulation layer 40, so that the stress and strain of the encapsulation layer 40 are smaller. The above-mentioned setting can also reduce the compressive stress on the flexible substrate 10 when bending to one side of the flexible substrate 10, and the flexible substrate 10 has a larger thickness, even if the biocompatible material layer 50 is separated from the flexible substrate 10, it will not affect the stability of the device.

[0065] Optionally, the material used for the biocompatible material layer includes at least one of polyurethane, silicone rubber, polyester fiber, polyvinyl pyrrolidone, polyetheretherketone, parylene, polymethyl methacrylate, polyvinyl alcohol, polylactic acid, polyethylene, natural rubber, collagen, protein fiber and gelatin.

[0066] Specifically, the above materials have good biocompatibility and a small Young's modulus. The use of the above materials makes the phototherapy device have better bending performance and can better adjust the position of the membrane layer with smaller bending strain, so that the strain of the packaging layer 40 and the water-blocking oxygen layer 20 is smaller when the phototherapy device is bent, and better avoid excessive strain of the packaging layer 40 and the water-blocking oxygen layer 20 when the phototherapy device is bent, resulting in breakage or delamination.

[0067] Figure 5 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention, optionally, refer to Figure 5 The biocompatible material layer 50 covers the side of the flexible substrate 10 , covers the surface of the flexible substrate 10 away from the water-blocking oxygen layer 20 , covers the side of the water-blocking oxygen layer 20 , covers the side of the encapsulation layer 40 , and covers the surface of the encapsulation layer 40 away from the light-emitting layer 30 .

[0068] This arrangement ensures that all surfaces of the phototherapy device that may come into contact with the user are made of the biocompatible material layer 50, further improving the biocompatibility of the phototherapy device and preventing the user from experiencing adverse reactions such as allergies and poisoning during the phototherapy process.

[0069] Optionally, the transmittance of the biocompatible material layer 50 in a preset wavelength range is greater than or equal to 80%; wherein the preset wavelength range is the light output wavelength range of the phototherapy device.

[0070] This arrangement enables the phototherapy device to have a higher light output rate and a better phototherapy effect.

[0071] Optionally, the preset wavelength range includes 380nm-1000nm.

[0072] Figure 6 is a schematic diagram of another phototherapy device provided by an embodiment of the present invention, optionally, refer to Figure 6 When the biocompatible material layer 50 is disposed on a side of the flexible substrate 10 away from the water-blocking oxygen layer 20 , an adhesive layer 60 is disposed between the biocompatible material layer 50 and the flexible substrate 10 ;

[0073] When the biocompatible material layer 50 is disposed on a side of the encapsulation layer 40 away from the light-emitting layer 30 , an adhesive layer 60 is disposed between the biocompatible material layer 50 and the encapsulation layer 40 .

[0074] Specifically, the adhesive layer 60 may be an OCA adhesive with high shear strain. The biocompatible material layer 50 is attached to the surface of the flexible substrate 10 and the packaging layer 40 through the adhesive layer 60, which is simple in process and helps to reduce process costs.

[0075] In addition, the biocompatible material layer 50 can also be prepared by other processes. For example, the biocompatible material layer 50 can be prepared on the surface of the flexible substrate 10 and the packaging layer 40 by coating and UV curing or thermal curing, or by chemical vapor deposition or molecular layer deposition.

[0076] It should be understood that the various forms of processes shown above can be used to reorder, add or delete steps. For example, the steps described in the present invention can be executed in parallel, sequentially or in different orders, as long as the desired results of the technical solution of the present invention can be achieved, and this document does not limit this.

[0077] The above specific implementations do not constitute a limitation on the protection scope of the present invention. It should be understood by those skilled in the art that various modifications, combinations, sub-combinations and substitutions can be made according to design requirements and other factors. Any modification, equivalent substitution and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A phototherapy device, characterized in that: include: Flexible substrate, water-oxygen barrier layer, luminescent layer, encapsulation layer and biocompatible material layer; Wherein, the flexible substrate, the water-blocking oxygen layer, the light-emitting layer and the encapsulation layer are stacked in sequence; The biocompatible material layer is arranged on a side of the flexible substrate away from the water-oxygen blocking layer and / or on a side of the encapsulation layer away from the light-emitting layer; The thickness of the biocompatible material layer is less than or equal to a first set value, and the Young's modulus of the biocompatible material layer is less than or equal to a second set value.

2. The phototherapy device according to claim 1, characterized in that The thickness, Young's modulus and Poisson's ratio of the biocompatible material layer are determined according to the thickness, Young's modulus and Poisson's ratio of the flexible substrate, the water-oxygen blocking layer, the light-emitting layer and the encapsulation layer.

3. The phototherapy device according to claim 2, characterized in that: The thickness, Young's modulus and Poisson's ratio of the biocompatible material layer are determined by the following formula: Among them, the film closest to the bending center is the first film, ν i is the Poisson's ratio of the i-th film, the total thickness of the flexible substrate 10, the water-blocking oxygen layer 20, the luminescent layer 30, the encapsulation layer 40 and the biocompatible material layer 50 is h, and the strain of the bottom surface of the film closest to the bending center when the phototherapy device is bent is ε bot , the height from the bottom to the top of the i-th film is z i , the height from the bottom to the top of the i-1th film is z i-1 , i is an integer greater than or equal to 1, the curvature radius of the bottom surface is R, v i is the Poisson's ratio of the i-th film, Ei is the Young's modulus of the i-th film, ε a is the strain of the plane at a height a from the bottom surface, and a is the distance from the set plane in the water-blocking oxygen layer or the encapsulation layer to the bottom surface.

4. The phototherapy device according to claim 1 or 3, characterized in that: The first set value is less than or equal to 5 mm, and the second set value is less than or equal to 10 GPa.

5. The phototherapy device according to claim 1, characterized in that: The thickness of the biocompatible material layer is smaller than the thickness of the packaging layer, and the sum of the thickness of the flexible substrate and the biocompatible material layer is smaller than the thickness of the packaging layer.

6. The phototherapy device according to claim 1, characterized in that: The material used for the biocompatible material layer includes at least one of polyurethane, silicone rubber, polyester fiber, polyvinyl pyrrolidone, polyetheretherketone, parylene, polymethyl methacrylate, polyvinyl alcohol, polylactic acid, polyethylene, natural rubber, collagen, protein fiber and gelatin.

7. The phototherapy device according to claim 1, characterized in that: The biocompatible material layer covers the side of the flexible substrate, the surface of the flexible substrate away from the water-oxygen blocking layer, the side of the water-oxygen blocking layer, the side of the encapsulation layer and the surface of the encapsulation layer away from the luminescent layer.

8. The phototherapy device according to claim 1, characterized in that: The transmittance of the biocompatible material layer within a preset wavelength range is greater than or equal to 80%; wherein the preset wavelength range is the light output wavelength range of the phototherapy device.

9. The phototherapy device according to claim 8, characterized in that: The preset wavelength range includes 380nm-1000nm.

10. The phototherapy device according to claim 1, characterized in that: When the biocompatible material layer is disposed on a side of the flexible substrate away from the water- and oxygen-blocking layer, an adhesive layer is disposed between the biocompatible material layer and the flexible substrate; When the biocompatible material layer is disposed on a side of the packaging layer away from the light-emitting layer, an adhesive layer is disposed between the biocompatible material layer and the packaging layer.

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