Neural intervention thrombolysis device

By designing a retractable inner casing mechanism and a nerve interventional thrombolysis device supporting the outer casing mechanism, the problem of difficult to accurately control the dose of thrombolysis drugs caused by the fixation of the catheter side pore section in the prior art is solved, and the dose and range of thrombolysis drugs are flexibly adjusted, reducing the risk of ineffective thrombolysis and systemic bleeding, and improving the effect and safety of thrombolysis.

CN119632630AInactive Publication Date: 2025-03-18AFFILIATED HOSPITAL OF NANTONG UNIV
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Patent Information

Application Number
CN202510105898.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-23
Publication Date
2025-03-18
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The length of the catheter end side pore segment of the existing neurointerventional thrombolysis device is fixed and cannot be flexibly adjusted according to the location and range of the thrombus, making it difficult to accurately control the dose of thrombolytic drugs, and there may be an ineffective thrombolytic range and risk of systemic bleeding.

Method used

A nerve interventional thrombolysis device including an inner cannula mechanism and a support for the outer cannula mechanism is designed. The amount of occlusion of the sealing liquid sac to the side hole of the discharge by the sealing liquid sac is adjusted through the end of the inner cannula body, and the dosage and scope of use of the thrombolysis drug are flexibly adjusted.

Benefits of technology

The dosage of thrombolytic drugs is flexibly adjusted according to the location and range of the thrombus, reducing the range of ineffective thrombolytic drugs, reducing the probability of excessive use of thrombolytic drugs, reducing the risk of systemic bleeding, and improving the effect and safety of thrombolytics.

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Abstract

The invention relates to the technical field of interventional therapy, and discloses a nerve intervention thrombolysis device which comprises a medicine guide inner cannula mechanism and a supporting outer cannula mechanism, the supporting outer cannula mechanism comprises a cannula unit, a sealing control unit, a disinfection isolation unit and a cannula pushing unit, the sealing control unit is fixedly installed at one end of the cannula unit, and the disinfection isolation unit is fixedly installed at the other end of the cannula unit. The disinfection and isolation unit is fixedly installed on the surface of the sealing control unit, and the tube pushing unit is fixedly arranged on one side of the sealing control unit. According to the nerve intervention thrombolysis device, during thrombolysis, the blocking number of the hole sealing liquid bag to the medicine discharging side holes can be adjusted through stretching and retracting of the end of the inner sleeve body in the outer sleeve body, so that the using number and the arrangement length of the medicine discharging side holes can be flexibly adjusted according to the thrombus position and range, and dosage control over thrombolysis medicine is facilitated; the ineffective thrombolysis range is reduced, the probability of excessive use of thrombolysis drugs is reduced, the whole body bleeding risk is reduced, and the safety is improved.
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Description

Technical Field

[0001] The present invention relates to the technical field of interventional therapy, and in particular to a neuro-interventional thrombolytic device. Background Art

[0002] Cerebral venous sinus thrombosis is a rare but serious vascular disease, the main manifestations of which are increased intracranial pressure, cerebral edema and cerebral infarction caused by venous drainage obstruction. Its main causes include infection, abnormal coagulation function, pregnancy and certain systemic diseases. At present, the treatment options for cerebral venous sinus thrombosis are mainly divided into the following categories: thrombectomy with a stent retriever, which captures and removes the thrombus with a mechanical stent retriever. This method is suitable for larger and centralized thrombi, but has limited effect on dispersed or tightly adherent thrombi; thrombectomy with a suction catheter, which uses the principle of negative pressure suction to remove the thrombus through a suction catheter. Although the operation is relatively simple, its adsorption capacity for larger loads or stubborn thrombi is limited; indwelling thrombolytic catheter, slow and continuous contact thrombolysis. A thrombolytic catheter is placed inside the thrombus, and thrombolytic drugs are slowly and continuously infused through the catheter so that the drugs directly contact the thrombus and gradually dissolve it. This method is particularly suitable for thrombi with a large thrombus load, residual thrombi that are difficult to completely remove, or scattered thrombi.

[0003] However, there is still a lack of thrombolytic catheters specifically designed for neurointervention on the market. Peripheral catheters are usually used as an alternative in clinical practice. The length of the side hole section of the catheter head of this alternative is fixed, and the length of the side hole section of the existing peripheral catheter cannot be flexibly adjusted according to the location and range of the thrombus. This fixed design makes it difficult to accurately control the dosage of thrombolytic drugs, and there may be a large range of ineffective thrombolysis, resulting in excessive use of thrombolytic drugs, which not only fails to improve the thrombolytic effect, but may even increase the risk of systemic bleeding. Summary of the invention

[0004] In view of the deficiencies of the prior art, the present invention provides a neurointerventional thrombolytic device to solve the problems mentioned in the above background.

[0005] The present invention provides the following technical solution: a neurointerventional thrombolytic device, comprising: a drug guiding inner sleeve mechanism and a supporting outer sleeve mechanism, and the supporting outer sleeve mechanism comprises a sleeve unit, a sealing control unit, a disinfection isolation unit and a pushing tube unit, the sealing control unit is fixedly installed on one end of the sleeve unit, the disinfection isolation unit is fixedly installed on the surface of the sealing control unit, and the pushing tube unit is fixedly arranged on one side of the sealing control unit.

[0006] Preferably, the drug-guiding inner sleeve mechanism comprises an inner sleeve body, a sealing liquid capsule, an inner tube developing ring, a liquid guiding channel, a side extension tube, a liquid injection head, a liquid injection rubber plug, a Y-tube joint and a sealing gasket. The sealing liquid capsule is fixedly mounted on the surface of the inner sleeve body close to the output end, the inner tube developing ring is fixedly sleeved on the surface of the output end of the inner sleeve body, the liquid guiding channel is through-opened inside the inner sleeve body, the side extension tube is integrally arranged on the surface of the inner sleeve body close to the input end, the liquid injection head is fixedly mounted on one end of the side extension tube, and the liquid injection head is connected to the sealing liquid capsule through the liquid guiding channel, the liquid injection rubber plug is fixedly connected to the inside of the liquid injection head, the Y-tube joint is fixedly mounted on the input end of the inner sleeve body, and the sealing gasket is fixedly connected to the inside of the Y-tube joint.

[0007] Preferably, the sleeve unit includes an outer sleeve body, a first outer tube developing ring, a second outer tube developing ring and a medicine discharge side hole, the first outer tube developing ring and the second outer tube developing ring are both fixedly sleeved on the surface of the outer sleeve body close to the output end, and the surface of the outer sleeve body located between the first outer tube developing ring and the second outer tube developing ring is a medicine discharge section, and the medicine discharge side hole is opened through the surface of the medicine discharge section.

[0008] Preferably, the sealing control unit includes an end seal, a sealing liquid sac and a liquid guide tube, the end seal is fixedly connected to the input end of the inner sleeve body, and there are two end seals, and the two end seals are relatively distributed, and both end seals are provided with mounting ports inside, the sealing liquid sac is fixedly connected inside the mounting port, and the liquid guide tube is fixedly connected to the surface of the sealing liquid sac.

[0009] Preferably, the sealing control unit also includes a liquid control cylinder, an end sealing piece, a constant pressure hole, a limit stop ring, a sliding seal ring, a guide ring, a guide groove and a circulation groove, the liquid control cylinder is fixedly connected between the two end sealing cylinders, the end sealing piece is fixedly connected to the inner wall of the liquid control cylinder, the constant pressure hole is penetrated and opened on the surface of the end sealing piece, the limit stop ring, the sliding seal ring and the guide ring are all fixedly connected to the inner wall of the liquid control cylinder, the guide groove is opened on the inner wall of the guide ring, and the circulation groove is opened on the surface of the guide ring.

[0010] Preferably, the sealing control unit also includes a threaded push pin, a torsion wheel, a threaded barrel, a guide ridge and a liquid pushing piston, the threaded push pin is rotatably connected to the inner walls of the two end sealing barrels through bearings, and the surface of the threaded push pin is slidably connected to the surface of the sliding seal ring, the torsion wheel is fixedly sleeved on one end of the threaded push pin, the threaded barrel is slidably connected to the inner wall of the guide ring, the guide ridge is integrally arranged on the surface of the threaded barrel, and the surface of the guide ridge is slidably connected to the inner wall of the guide groove, and the inner wall of the threaded barrel is threadedly connected to the surface of the threaded push pin, the liquid pushing piston is fixedly installed at one end of the threaded barrel, and the transmission fluid is filled between the liquid pushing piston and the sealing liquid bag.

[0011] Preferably, the sealing control unit further comprises a tube support tube and a flushing port, wherein the tube support tube is fixedly connected between the two end sealing tubes, and the flushing port is penetrated and opened on a side of the surface of the tube support tube away from the liquid control tube.

[0012] Preferably, the disinfection isolation unit comprises an isolation shell and a light-transmitting plate, the isolation shell is fixedly sleeved between the two end sealing cylinders, and the light-transmitting plate is fixedly mounted on the surface of the isolation shell.

[0013] Preferably, the disinfection isolation unit also includes a sealing block, a flushing tube, a flushing rubber plug, a spring piece and a first dust cover, the sealing block is fixedly connected to the inner wall of the liquid control cylinder, the flushing tube is integrally arranged inside the sealing block, the flushing rubber plug is fixedly installed inside the flushing tube, the spring piece is movably sleeved on the surface of the flushing tube, the first dust cover is integrally arranged on the surface of the spring piece, and the first dust cover is movably engaged with the flushing tube.

[0014] Preferably, the push pipe unit includes a connecting pipe, a sealing shell, an insertion head, a second dust cover, a guide plate, a driving rotating shaft, a driven rotating shaft, a sealing ring, an adjusting wheel and a damping push pipe wheel, the connecting pipe is fixedly connected to one end of the sealing cylinder away from one side end of the outer sleeve body, the sealing shell is fixedly connected to one end of the connecting pipe, the insertion head is fixedly installed on the end of the sealing shell away from the connecting pipe, the second dust cover is integrally arranged on the surface of the insertion head, and the second dust cover is movably engaged with the insertion head, the guide plate is fixedly connected to the inside of the sealing shell, the driving rotating shaft and the driven rotating shaft are both rotatably connected to the inner wall of the connecting pipe, the sealing ring is fixedly connected to the inner wall of the sealing shell, and the surface of the sealing ring is slidably connected to the surface of the driving rotating shaft, the damping push pipe wheel is respectively fixedly sleeved on the surface of the driving rotating shaft and the surface of the driven rotating shaft, the adjusting wheel is fixedly sleeved on one end of the driving rotating shaft, and a wheel groove is provided on the surface of the damping push pipe wheel.

[0015] Compared with the prior art, the present invention has the following beneficial effects: The neurointerventional thrombolytic device, through the drug-guiding inner sleeve mechanism, sleeve unit, sealing control unit, disinfection isolation unit and pushing tube unit, can adjust the amount of blocking of the drug-discharging side holes by the sealing liquid capsule through the extension and retraction of the end of the inner sleeve body inside the outer sleeve body during thrombolysis, so that the number of drug-discharging side holes used and the arrangement length can be flexibly adjusted according to the location and range of the thrombus, which facilitates the dosage control of the thrombolytic drug, reduces the scope of ineffective thrombolysis, reduces the probability of overdose of thrombolytic drugs, reduces the risk of systemic bleeding, and improves safety.

[0016] The neurointerventional thrombolytic device, through the inner sleeve body, sealing liquid capsule, inner tube developing ring, liquid guide channel, side extension tube, injection head, injection rubber plug, Y-tube joint and sealing gasket, can inject liquid medicine through the inner sleeve body when in use, and adjust the thrombolytic length by controlling the number of the sealing liquid capsule blocking the drug discharge side holes.

[0017] The neurointerventional thrombolytic device, through the outer sleeve body, the first outer tube developing ring, the second outer tube developing ring and the medicine discharge side hole, can support the inner sleeve body in the body when in use, and ensure the discharge of medicine at the thrombolytic position through the medicine discharge side hole.

[0018] The neurointerventional thrombolytic device, through the end sealing tube, sealing liquid sac, liquid guide tube, liquid control tube, end sealing plate, constant pressure hole, limit baffle ring, sliding sealing ring, guide ring, guide groove, flow groove, threaded push column, twist wheel, threaded tube, guide ridge, liquid pushing piston, tube support tube and flushing port, can control the expansion of the sealing liquid sac to adjust the sealing effect inside the outer sleeve mechanism during use, ensure that the reflux of body fluid is reduced when the inner sleeve body is pulled or pushed, and ensure that the disinfectant is isolated when it is left in place.

[0019] The neurointerventional thrombolytic device, through the isolation shell, light-transmitting plate, blocking block, flushing tube, flushing rubber plug, shrapnel and first dust cover, can improve the disinfection effect of the device and reduce the probability of infection by filling disinfectant inside the isolation shell when indwelling.

[0020] The neurointerventional thrombolysis device, through the provided connecting pipe, sealing shell, insertion head, second dust cover, guide plate, active rotating shaft, driven rotating shaft, sealing ring, adjusting wheel and damping tube pushing wheel, can achieve fine adjustment by twisting the adjusting wheel when the inner sleeve body is about to reach the thrombolysis position during installation, thereby improving the installation accuracy of the inner sleeve body. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the structure of the present invention; Figure 2 This is a schematic diagram of the structure of the drug guiding inner sleeve mechanism and the supporting outer sleeve mechanism of the present invention; Figure 3 It is a cross-sectional view of the sealing liquid capsule of the present invention; Figure 4 It is a cross-sectional view of the location of the liquid guide channel of the present invention; Figure 5 It is a schematic diagram of the structure of the push pipe unit of the present invention; Figure 6 It is a cross-sectional view at the position of the side extension tube of the present invention; Figure 7 This is a schematic diagram of the internal explosion structure of the push pipe unit of the present invention; Figure 8It is an internal cross-sectional view of the push tube unit of the present invention; Fig. 9 This is a schematic diagram of the structure of the disinfection isolation unit of the present invention; Fig.10 A cross-sectional view of the internal structure at the location of the disinfection isolation unit of the present invention; Fig.11 This is a schematic diagram of the internal explosion structure at the location of the disinfection isolation unit of the present invention; Fig.12 It is a structural schematic diagram of the threaded push pin position of the present invention; Fig.13 It is a schematic diagram of the explosion structure at the flushing pipe position of the present invention.

[0022] In the figure: 101, inner sleeve body; 102, sealing liquid capsule; 103, inner tube developing ring; 104, liquid guiding channel; 105, side extension tube; 106, liquid injection head; 107, liquid injection rubber plug; 108, Y-tube joint; 109, sealing pad; 201, outer sleeve body; 202, first outer tube developing ring; 203, second outer tube developing ring; 204, medicine discharge side hole; 301, end sealing cylinder; 302, sealing liquid capsule; 303, liquid guiding tube; 304, liquid control cylinder; 305, end sealing sheet; 306, constant pressure hole; 307, limit stop ring; 308, sliding seal ring; 309, guide ring; 310, guide groove; 311. Circulation slot; 312. Threaded push column; 313. Twist wheel; 314. Threaded tube; 315. Guide ridge; 316. Liquid pushing piston; 317. Support tube; 318. Flushing port; 401. Isolation shell; 402. Light-transmitting plate; 403. Blocking block; 404. Flushing tube; 405. Flushing rubber plug; 406. Shrapnel; 407. First dust cover; 501. Connecting tube; 502. Sealing shell; 503. Insertion head; 504. Second dust cover; 505. Guide plate; 506. Active rotating shaft; 507. Driven rotating shaft; 508. Sealing ring; 509. Adjusting wheel; 510. Damping tube pushing wheel. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] See also Figure 1-13A neurointerventional thrombolytic device comprises: a drug-guiding inner sleeve mechanism and a supporting outer sleeve mechanism, and the supporting outer sleeve mechanism comprises a sleeve unit, a sealing control unit, a disinfection isolation unit and a tube pushing unit, the sealing control unit is fixedly mounted on one end of the sleeve unit, the disinfection isolation unit is fixedly mounted on the surface of the sealing control unit, and the tube pushing unit is fixedly arranged on one side of the sealing control unit. Through the drug-guiding inner sleeve mechanism, the sleeve unit, the sealing control unit, the disinfection isolation unit and the tube pushing unit, the amount of blocking of the drug discharge side hole 204 by the sealing liquid capsule 102 can be adjusted by telescoping the end of the inner sleeve body 101 inside the outer sleeve body 201 during thrombolysis, so that the use amount and arrangement length of the drug discharge side hole 204 can be flexibly adjusted according to the location and range of the thrombus, which facilitates the dosage control of the thrombolytic drug, reduces the scope of ineffective thrombolysis, reduces the probability of overdose of thrombolytic drugs, reduces the risk of systemic bleeding, and improves safety.

[0025] Among them; the drug guiding inner sleeve mechanism includes an inner sleeve body 101, a sealing liquid capsule 102, an inner tube developing ring 103, a liquid guiding channel 104, a side extension tube 105, a liquid injection head 106, a liquid injection rubber plug 107, a Y-tube joint 108 and a sealing gasket 109, the sealing liquid capsule 102 is fixedly mounted on the surface of the inner sleeve body 101 near the output end, the inner tube developing ring 103 is fixedly sleeved on the surface of the inner sleeve body 101 at the output end, the liquid guiding channel 104 is opened through the inner sleeve body 101, the side extension tube 105 is integrally arranged on the surface of the inner sleeve body 101 near the input end, the liquid injection head 106 is fixedly mounted on one end of the side extension tube 105, and the liquid injection head 106 is connected to the inner sleeve body 101. The liquid conducting channel 104 is connected with the sealing liquid capsule 102, the liquid injection rubber plug 107 is fixedly connected to the inside of the liquid injection head 106, the Y-tube joint 108 is fixedly installed at the input end of the inner sleeve body 101, and the sealing gasket 109 is fixedly connected to the inside of the Y-tube joint 108. By arranging the inner sleeve body 101, the sealing liquid capsule 102, the inner tube developing ring 103, the liquid conducting channel 104, the side extension tube 105, the liquid injection head 106, the liquid injection rubber plug 107, the Y-tube joint 108 and the sealing gasket 109, the drug solution can be injected through the inner sleeve body 101 when in use, and the thrombolysis length can be adjusted by controlling the number of the drug discharge side holes 204 blocked by the sealing liquid capsule 102.

[0026] Among them; the sleeve unit includes an outer sleeve body 201, a first outer tube developing ring 202, a second outer tube developing ring 203 and a drug discharge side hole 204, the first outer tube developing ring 202 and the second outer tube developing ring 203 are both fixedly sleeved on the surface of the outer sleeve body 201 close to the output end, and the surface of the outer sleeve body 201 located between the first outer tube developing ring 202 and the second outer tube developing ring 203 is a drug discharge section, the drug discharge side hole 204 runs through the surface of the drug discharge section, and the length of the side hole section is twenty centimeters. Through the outer sleeve body 201, the first outer tube developing ring 202, the second outer tube developing ring 203 and the drug discharge side hole 204, the inner sleeve body 101 can be supported in the body during use, and the drug discharge side hole 204 ensures that the drug solution is discharged at the thrombolysis position. Compared with the traditional method, the length of the drug discharge section is sufficient to not target the special anatomical structure of the cerebral venous sinus, so it is convenient to cover the thrombus area with a large load.

[0027] Among them; the sealing control unit includes an end sealing cylinder 301, a sealing liquid capsule 302 and a liquid guide tube 303, the end sealing cylinder 301 is fixedly connected to the input end of the inner sleeve body 101, and the number of the end sealing cylinders 301 is two, and the two end sealing cylinders 301 are relatively distributed, and the inside of the two end sealing cylinders 301 is provided with a mounting port, the sealing liquid capsule 302 is fixedly connected to the inside of the mounting port, and the liquid guide tube 303 is fixedly connected to the surface of the sealing liquid capsule 302.

[0028] Among them; the sealing control unit also includes a liquid control cylinder 304, an end sealing piece 305, a constant pressure hole 306, a limit stop ring 307, a sliding seal ring 308, a guide ring 309, a guide groove 310 and a circulation groove 311. The liquid control cylinder 304 is fixedly connected between the two end sealing cylinders 301, the end sealing piece 305 is fixedly connected to the inner wall of the liquid control cylinder 304, the constant pressure hole 306 runs through the surface of the end sealing piece 305, the limit stop ring 307, the sliding seal ring 308 and the guide ring 309 are all fixedly connected to the inner wall of the liquid control cylinder 304, the guide groove 310 is opened on the inner wall of the guide ring 309, and the circulation groove 311 is opened on the surface of the guide ring 309.

[0029] Among them; the sealing control unit also includes a threaded push pin 312, a torsion wheel 313, a threaded barrel 314, a guide ridge 315 and a liquid pushing piston 316, the threaded push pin 312 is rotatably connected to the inner walls of the two end sealing barrels 301 through bearings, and the surface of the threaded push pin 312 is slidingly connected to the surface of the sliding seal ring 308, the torsion wheel 313 is fixedly sleeved on one end of the threaded push pin 312, the threaded barrel 314 is slidingly connected to the inner wall of the guide ring 309, the guide ridge 315 is integrally arranged on the surface of the threaded barrel 314, and the surface of the guide ridge 315 is slidingly connected to the inner wall of the guide groove 310, and the inner wall of the threaded barrel 314 is threadedly connected to the surface of the threaded push pin 312, the liquid pushing piston 316 is fixedly installed at one end of the threaded barrel 314, and the transmission fluid is filled between the liquid pushing piston 316 and the sealing liquid bag 302.

[0030] Among them, the sealing control unit also includes a support tube tube 317 and a flushing port 318. The support tube tube 317 is fixedly connected between the two end sealing tubes 301, and the flushing port 318 is opened through the side of the support tube tube 317 surface away from the liquid control tube 304. Through the end sealing tube 301, the sealing liquid capsule 302, the liquid guide tube 303, the liquid control tube 304, the end sealing piece 305, the constant pressure hole 306, the limit stop ring 307, the sliding seal ring 308, the guide ring 309, the guide groove 310, the flow groove 311, the threaded push column 312, the torsion wheel 313, the threaded tube 314, the guide ridge 315, the liquid pushing piston 316, the support tube tube 317 and the flushing port 318, the sealing effect of the inner part of the outer sleeve mechanism can be adjusted by controlling the expansion of the sealing liquid capsule 302 during use, so as to reduce the reflux of body fluid when the inner sleeve body 101 is pulled or pushed, and to ensure that the disinfectant is isolated when it is left in place.

[0031] The disinfection isolation unit comprises an isolation shell 401 and a light-transmitting plate 402 . The isolation shell 401 is fixedly sleeved between the two end sealing cylinders 301 , and the light-transmitting plate 402 is fixedly mounted on the surface of the isolation shell 401 .

[0032] Among them; the disinfection isolation unit also includes a blocking block 403, a flushing tube 404, a flushing rubber plug 405, a spring 406 and a first dust cover 407, the blocking block 403 is fixedly connected to the inner wall of the liquid control cylinder 304, the flushing tube 404 is integrally arranged inside the blocking block 403, the flushing rubber plug 405 is fixedly installed inside the flushing tube 404, the spring 406 is movably sleeved on the surface of the flushing tube 404, the first dust cover 407 is integrally arranged on the surface of the spring 406, and the first dust cover 407 is movably engaged with the flushing tube 404, through the isolation shell 401, the light-transmitting plate 402, the blocking block 403, the flushing tube 404, the flushing rubber plug 405, the spring 406 and the first dust cover 407 are arranged, the disinfection effect of the device can be improved by filling the isolation shell 401 with disinfectant when it is left in place, thereby reducing the probability of infection.

[0033] Among them, the tube pushing unit includes a connecting tube 501, a sealing shell 502, an insertion head 503, a second dust cover 504, a guide plate 505, a driving shaft 506, a driven shaft 507, a sealing ring 508, an adjusting wheel 509 and a damping tube pushing wheel 510. The connecting tube 501 is fixedly connected to one end of the sealing cylinder 301 at one end away from the outer sleeve body 201, the sealing shell 502 is fixedly connected to one end of the connecting tube 501, the insertion head 503 is fixedly installed at one end of the sealing shell 502 away from the connecting tube 501, the second dust cover 504 is integrally arranged on the surface of the insertion head 503, and the second dust cover 504 is movably engaged with the insertion head 503, the guide plate 505 is fixedly connected to the inside of the sealing shell 502, the driving shaft 506 and the driven shaft 507 are both rotatably connected to the connecting tube 501. The inner wall, the sealing ring 508 is fixedly connected to the inner wall of the sealing shell 502, and the surface of the sealing ring 508 is slidably connected to the surface of the driving shaft 506, the damping tube push wheel 510 is respectively fixedly sleeved on the surface of the driving shaft 506 and the surface of the driven shaft 507, the adjusting wheel 509 is fixedly sleeved on one end of the driving shaft 506, and the surface of the damping tube push wheel 510 is provided with a wheel groove, through the arranged connecting pipe 501, sealing shell 502, insertion head 503, second dust cover 504, guide plate 505, driving shaft 506, driven shaft 507, sealing ring 508, adjusting wheel 509 and damping tube push wheel 510, when the inner sleeve body 101 is about to reach the thrombolysis position during installation, fine adjustment can be achieved by twisting the adjusting wheel 509, thereby improving the installation accuracy of the inner sleeve body 101.

[0034] Working principle: When the twist wheel 313 is twisted, the twist wheel 313 drives the threaded push column 312 to rotate. When the threaded push column 312 rotates, it pushes the threaded cylinder 314 to move toward the middle or toward the outside. When the threaded cylinder 314 moves toward the middle, the space between the liquid pushing piston 316 and the sealing liquid capsule 302 increases to form a negative pressure, the sealing liquid capsule 302 shrinks, and the sealing effect decreases. When the threaded cylinder 314 moves toward the outside, the space between the liquid pushing piston 316 and the sealing liquid capsule 302 decreases to form a positive pressure, the sealing liquid capsule 302 expands, and the sealing effect increases. When in use, the medical staff first delivers the outer sleeve body 201 to the human body through the cooperation of the medical equipment to ensure that the drug discharge side hole 204 is located at the designated position, then pulls out the nerve guide wire inside the outer sleeve body 201, and inserts the inner sleeve body 101 connected to the Y tube and adjusted from the insertion head 503 into the sealing shell 502, and then continues to push it forward. After the sealing liquid capsule 102 has completely entered the outer sleeve body 201, twist the twist wheel 313 away from the side of the sealing shell 502 to make the sealing liquid capsule 302 on the same side expand and seal, to ensure that the inner sleeve body 101 can be sealed with the sealing liquid capsule 302 while being able to slide smoothly when being pushed forward, and then continue to push the inner sleeve body 101 until the end of the inner sleeve body 101 reaches the inner side of the drug discharge side hole 204, and then adjust the position of the end of the inner sleeve body 101. When adjusting the position of the inner sleeve body 101, twist the adjusting wheel 509, and the adjusting wheel 509 drives the damping tube push wheel 510 to rotate through the active rotating shaft 506, and the damping push tube wheel 510 rotates. When the tube wheel 510 rotates, the inner sleeve body 101 is moved by friction, thereby achieving fine adjustment. The deeper the inner sleeve body 101 extends, the more the drug discharge side holes 204 are blocked, the fewer the drug discharge side holes 204 that can discharge the drug, the shorter the arrangement length of the drug discharge side holes 204, and the slower the drug leakage rate. After the inner sleeve body 101 reaches the specified position, the injection rubber plug 107 is inserted through a syringe and physiological saline is injected, and the physiological saline enters from the liquid guide channel 104 The sealing liquid capsule 102 is used to expand the sealing liquid capsule 102, and the expanded sealing liquid capsule 102 closes the blocked drug discharge side hole 204, and then the twist wheel 313 close to the side of the sealing shell 502 is twisted to expand and seal the sealing liquid capsule 302 on the same side, so as to ensure that the two sealing liquid capsules 302 form a seal, and then the medicine is injected into the inner sleeve body 101 through the Y tube, and the medicine enters the outer sleeve body 201 from the inner sleeve body 101, and then seeps out from the drug discharge side hole 204 to discharge the medicine; Then insert a syringe filled with an appropriate amount of physiological saline into the flushing rubber plug 405 and continuously draw and pull it, so as to continuously flush the body fluid that flows back into the isolation shell 401 during installation with the physiological saline, and extract the waste liquid after repeated flushing for several times; After the medicine is discharged, the twist wheel 313 on the side away from the sealing shell 502 is twisted to shrink the sealing liquid capsule 302 on the same side, and then the injection rubber plug 107 is inserted through the syringe, and then the injected physiological saline is extracted. After the physiological saline is extracted from the sealing liquid capsule 102, the sealing liquid capsule 102 shrinks, and then the inner sleeve body 101 is slowly extracted. When the end of the inner sleeve body 101 passes over the sealing liquid capsule 302, the twist wheel 313 on its surface is quickly twisted to expand and seal it. After the inner sleeve body 101 is completely extracted, the twist wheel 313 is twisted to expand and seal it. The twist wheel 313 close to one side of the sealing shell 502 is turned to expand and seal the sealing liquid sac 302 on the same side, thereby ensuring that the two sealing liquid sacs 302 form a seal, and then the body fluid that flows back into the isolation shell 401 is continuously flushed with saline again. After the flushing is completed, the sealing shell 502 is filled with disinfectant through the flushing rubber plug 405 to isolate the bacteria. The disinfectant is replaced regularly every day until the disinfectant is discharged before the injection again, and flushed with saline, and then the inner cannula body 101 can be inserted.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A neurointerventional thrombolytic device, characterized in that: include: The invention discloses a drug guiding inner sleeve mechanism and a supporting outer sleeve mechanism, and the supporting outer sleeve mechanism comprises a sleeve unit, a sealing control unit, a disinfection isolation unit and a tube pushing unit, wherein the sealing control unit is fixedly mounted on one end of the sleeve unit, the disinfection isolation unit is fixedly mounted on the surface of the sealing control unit, and the tube pushing unit is fixedly arranged on one side of the sealing control unit.

2. A neurointerventional thrombolytic device according to claim 1, characterized in that: The drug-guiding inner cannula mechanism comprises an inner cannula body (101), a sealing liquid capsule (102), an inner tube developing ring (103), a liquid guiding channel (104), a side extension tube (105), a liquid injection head (106), a liquid injection rubber plug (107), a Y-tube joint (108) and a sealing gasket (109); the sealing liquid capsule (102) is fixedly mounted on a surface of the inner cannula body (101) close to the output end; the inner tube developing ring (103) is fixedly sleeved on a surface of the output end of the inner cannula body (101); and the liquid guiding channel (104) is opened through the inner cannula body (101). The side extension tube (105) is integrally arranged on a surface of the inner sleeve body (101) close to the input end, the liquid injection head (106) is fixedly mounted on one end of the side extension tube (105), and the liquid injection head (106) is connected to the sealing liquid capsule (102) through a liquid guide channel (104), the liquid injection rubber plug (107) is fixedly connected to the inside of the liquid injection head (106), the Y-tube joint (108) is fixedly mounted on the input end of the inner sleeve body (101), and the sealing pad (109) is fixedly connected to the inside of the Y-tube joint (108).

3. A neurointerventional thrombolytic device according to claim 1, characterized in that: The sleeve unit comprises an outer sleeve body (201), a first outer tube developing ring (202), a second outer tube developing ring (203) and a medicine discharge side hole (204); the first outer tube developing ring (202) and the second outer tube developing ring (203) are both fixedly sleeved on a surface of the outer sleeve body (201) close to an output end; the surface of the outer sleeve body (201) between the first outer tube developing ring (202) and the second outer tube developing ring (203) is a medicine discharge section; the medicine discharge side hole (204) is opened through the surface of the medicine discharge section.

4. A neurointerventional thrombolytic device according to claim 3, characterized in that: The sealing control unit comprises an end sealing tube (301), a sealing liquid capsule (302) and a liquid guiding tube (303); the end sealing tube (301) is fixedly connected to the input end of the inner sleeve body (101); there are two end sealing tubes (301), and the two end sealing tubes (301) are relatively distributed, and the insides of the two end sealing tubes (301) are both provided with mounting openings, the sealing liquid capsule (302) is fixedly connected to the inside of the mounting opening, and the liquid guiding tube (303) is fixedly connected to the surface of the sealing liquid capsule (302).

5. The neurointerventional thrombolytic device according to claim 3, characterized in that: The sealing control unit further comprises a liquid control cylinder (304), an end sealing piece (305), a constant pressure hole (306), a limit stop ring (307), a sliding seal ring (308), a guide ring (309), a guide groove (310) and a circulation groove (311); the liquid control cylinder (304) is fixedly connected between the two end sealing cylinders (301); the end sealing piece (305) is fixedly connected to the inner wall of the liquid control cylinder (304); the constant pressure hole (306) is penetrated and opened on the surface of the end sealing piece (305); the limit stop ring (307), the sliding seal ring (308) and the guide ring (309) are all fixedly connected to the inner wall of the liquid control cylinder (304); the guide groove (310) is opened on the inner wall of the guide ring (309); and the circulation groove (311) is opened on the surface of the guide ring (309).

6. A neurointerventional thrombolytic device according to claim 5, characterized in that: The sealing control unit further comprises a threaded push pin (312), a twist wheel (313), a threaded barrel (314), a guide ridge (315) and a liquid pushing piston (316); the threaded push pin (312) is rotatably connected to the inner walls of the two end sealing barrels (301) via bearings, and the surface of the threaded push pin (312) is slidably connected to the surface of the sliding seal ring (308); the twist wheel (313) is fixedly sleeved on one end of the threaded push pin (312); the threaded barrel (314) The guide ridge (315) is integrally arranged on the surface of the threaded barrel (314), and the surface of the guide ridge (315) is slidably connected to the inner wall of the guide groove (310), and the inner wall of the threaded barrel (314) is threadedly connected to the surface of the threaded push column (312), and the push piston (316) is fixedly installed on one end of the threaded barrel (314), and the space between the push piston (316) and the sealing liquid bag (302) is filled with transmission fluid.

7. A neurointerventional thrombolytic device according to claim 6, characterized in that: The sealing control unit further comprises a supporting tube tube (317) and a flushing port (318); the supporting tube tube (317) is fixedly connected between the two end sealing tubes (301); and the flushing port (318) is opened through a side of the surface of the supporting tube tube (317) away from the liquid control tube (304).

8. The neurointerventional thrombolytic device according to claim 7, characterized in that: The disinfection isolation unit comprises an isolation shell (401) and a light-transmitting plate (402); the isolation shell (401) is fixedly sleeved between two end sealing cylinders (301); and the light-transmitting plate (402) is fixedly mounted on the surface of the isolation shell (401).

9. The neurointerventional thrombolytic device according to claim 8, characterized in that: The disinfection isolation unit further comprises a blocking block (403), a flushing tube (404), a flushing rubber plug (405), a spring piece (406) and a first dust cover (407); the blocking block (403) is fixedly connected to the inner wall of the liquid control cylinder (304); the flushing tube (404) is integrally arranged inside the blocking block (403); the flushing rubber plug (405) is fixedly installed inside the flushing tube (404); the spring piece (406) is movably sleeved on the surface of the flushing tube (404); the first dust cover (407) is integrally arranged on the surface of the spring piece (406), and the first dust cover (407) is movably engaged with the flushing tube (404).

10. The neurointerventional thrombolytic device according to claim 7, characterized in that: The tube pushing unit comprises a connecting tube (501), a sealing shell (502), an insertion head (503), a second dust cover (504), a guide plate (505), a driving shaft (506), a driven shaft (507), a sealing ring (508), an adjusting wheel (509) and a damping tube pushing wheel (510); the connecting tube (501) is fixedly connected to one end of a sealing cylinder (301) at one side away from the outer sleeve body (201); the sealing shell (502) is fixedly connected to one end of the connecting tube (501); the insertion head (503) is fixedly installed at one end of the sealing shell (502) away from the connecting tube (501); the second dust cover (504) is integrally arranged on the surface of the insertion head (503); and the The second dust cover (504) is movably engaged with the insertion head (503); the guide plate (505) is fixedly connected to the inside of the sealing shell (502); the driving shaft (506) and the driven shaft (507) are both rotatably connected to the inner wall of the connecting pipe (501); the sealing ring (508) is fixedly connected to the inner wall of the sealing shell (502); the surface of the sealing ring (508) is slidably connected to the surface of the driving shaft (506); the damping tube pusher wheel (510) is respectively fixedly sleeved on the surface of the driving shaft (506) and the surface of the driven shaft (507); the adjusting wheel (509) is fixedly sleeved on one end of the driving shaft (506); and a wheel groove is provided on the surface of the damping tube pusher wheel (510).