Bamboo alginate functional dressing and preparation method thereof

Abstract

The invention belongs to the field of medical dressings, and particularly relates to a bamboo alginate functional dressing and a preparation method thereof. The dressing comprises the following components in parts by weight: 1-4.2 parts of sodium alginate, 0.05-0.4 part of sodium hyaluronate, 0.25-2 parts of collagen, 4.5-31 parts of bioactive glass powder and 62-95 parts of bamboo fiber. The dressing can quickly promote healing of a wound surface, and healed wound surface is smooth and resilient and is less prone to scar proliferation; and the dressing has the functional characteristics of antisepsis, imbibition, hemostasis, adhesion prevention, no cytotoxicity and the like, and can satisfy various requirements for wound surface healing. According to the preparation method of the bamboo alginate functional dressing, the problem that the alginate medical dressing is cracked after exudate imbibition is solved, thereby facilitating dressing change by medical personnel.

Description

technical field

[0001] The invention belongs to the field of medical dressings, and in particular relates to a bamboo alginate functional dressing and a preparation method thereof. Background technique

[0002] Alginate is a polysaccharide extracted from brown algae kelp or sargassum, and is a natural three-dimensional network polymer material. It has excellent properties such as non-toxic, non-irritating, high hygroscopicity, and biocompatibility, and is widely used in drug delivery systems and pharmaceutical fields. After the flaky alginate dressing absorbs the wound exudate, it is easy to form a gel. During the gel formation process, the calcium ions in the alginate dressing exchange with the sodium ions in the exudate, destroying the three-dimensional structure of the alginate. The mesh structure causes the flaky alginate dressing to partially break and cannot form a complete flaky gel, which is inconvenient for medical staff to change the dressing.

[0003] Bamboo fib...

Examples

Embodiment 1

[0031] A bamboo alginate functional dressing, which is composed of sodium alginate, sodium hyaluronate, collagen, bioactive glass powder and bamboo fiber, and the components are calculated in parts by weight: 1 part of sodium alginate, hyaluronic acid 0.05 parts of sodium, 0.25 parts of collagen, 4.5 parts of bioactive glass powder, and 94.2 parts of bamboo fiber.

[0032] The preparation method of described bamboo alginate functional dressing, the concrete steps of its preparation method are as follows:

[0033] (1) Dissolve 2 g of sodium alginate in 98 g of deionized water, and stir until all the sodium alginate is dissolved to obtain a sodium alginate gel, which is set aside.

[0034] (2) Dissolve 0.5 g of sodium hyaluronate in 99.5 g of deionized water, and stir until the sodium hyaluronate is completely dissolved to obtain sodium hyaluronate gel, which is set aside.

[0035] (3) Dissolve 1 g of collagen in 99 g of deionized water, and stir until the collagen is completel...

Embodiment 2

[0040] A bamboo alginate functional dressing, which is composed of sodium alginate, sodium hyaluronate, collagen, bioactive glass powder and bamboo fiber, and the components are calculated in parts by weight: 1 part of sodium alginate, hyaluronic acid 0.05 parts of sodium, 0.25 parts of collagen, 4.5 parts of bioactive glass powder, and 94.2 parts of bamboo fiber.

[0041] The preparation method of described bamboo alginate functional dressing, the concrete steps of its preparation method are as follows:

[0042] (1) Dissolve 2 g of sodium alginate in 98 g of deionized water, and stir until all the sodium alginate is dissolved to obtain a sodium alginate gel, which is set aside.

[0043] (2) Dissolve 0.5 g of sodium hyaluronate in 99.5 g of deionized water, and stir until the sodium hyaluronate is completely dissolved to obtain sodium hyaluronate gel, which is set aside.

[0044] (3) Dissolve 1 g of collagen in 99 g of deionized water, and stir until the collagen is completel...

Embodiment 3

[0049] A bamboo alginate functional dressing, which is composed of sodium alginate, sodium hyaluronate, collagen, bioactive glass powder and bamboo fiber, and the components are calculated in parts by weight: 1 part of sodium alginate, hyaluronic acid 0.05 parts of sodium, 0.25 parts of collagen, 4.5 parts of bioactive glass powder, and 94.2 parts of bamboo fiber.

[0050] The preparation method of described bamboo alginate functional dressing, the concrete steps of its preparation method are as follows:

[0051] (1) Dissolve 2 g of sodium alginate in 98 g of deionized water, and stir until all the sodium alginate is dissolved to obtain a sodium alginate gel, which is set aside.

[0052] (2) Dissolve 0.5 g of sodium hyaluronate in 99.5 g of deionized water, and stir until the sodium hyaluronate is completely dissolved to obtain sodium hyaluronate gel, which is set aside.

[0053] (3) Dissolve 1 g of collagen in 99 g of deionized water, and stir until the collagen is completel...

technical field

[0001] The invention belongs to the field of medical dressings, and in particular relates to a bamboo alginate functional dressing and a preparation method thereof. Background technique

[0002] Alginate is a polysaccharide extracted from brown algae kelp or sargassum, and is a natural three-dimensional network polymer material. It has excellent properties such as non-toxic, non-irritating, high hygroscopicity, and biocompatibility, and is widely used in drug delivery systems and pharmaceutical fields. After the flaky alginate dressing absorbs the wound exudate, it is easy to form a gel. During the gel formation process, the calcium ions in the alginate dressing exchange with the sodium ions in the exudate, destroying the three-dimensional structure of the alginate. The mesh structure causes the flaky alginate dressing to partially break and cannot form a complete flaky gel, which is inconvenient for medical staff to change the dressing.

[0003] Bamboo fib...

Examples

Embodiment 1

[0031] A bamboo alginate functional dressing, which is composed of sodium alginate, sodium hyaluronate, collagen, bioactive glass powder and bamboo fiber, and the components are calculated in parts by weight: 1 part of sodium alginate, hyaluronic acid 0.05 parts of sodium, 0.25 parts of collagen, 4.5 parts of bioactive glass powder, and 94.2 parts of bamboo fiber.

[0032] The preparation method of described bamboo alginate functional dressing, the concrete steps of its preparation method are as follows:

[0033] (1) Dissolve 2 g of sodium alginate in 98 g of deionized water, and stir until all the sodium alginate is dissolved to obtain a sodium alginate gel, which is set aside.

[0034] (2) Dissolve 0.5 g of sodium hyaluronate in 99.5 g of deionized water, and stir until the sodium hyaluronate is completely dissolved to obtain sodium hyaluronate gel, which is set aside.

[0035] (3) Dissolve 1 g of collagen in 99 g of deionized water, and stir until the collagen is completel...

Embodiment 2

[0040] A bamboo alginate functional dressing, which is composed of sodium alginate, sodium hyaluronate, collagen, bioactive glass powder and bamboo fiber, and the components are calculated in parts by weight: 1 part of sodium alginate, hyaluronic acid 0.05 parts of sodium, 0.25 parts of collagen, 4.5 parts of bioactive glass powder, and 94.2 parts of bamboo fiber.

[0041] The preparation method of described bamboo alginate functional dressing, the concrete steps of its preparation method are as follows:

[0042] (1) Dissolve 2 g of sodium alginate in 98 g of deionized water, and stir until all the sodium alginate is dissolved to obtain a sodium alginate gel, which is set aside.

[0043] (2) Dissolve 0.5 g of sodium hyaluronate in 99.5 g of deionized water, and stir until the sodium hyaluronate is completely dissolved to obtain sodium hyaluronate gel, which is set aside.

[0044] (3) Dissolve 1 g of collagen in 99 g of deionized water, and stir until the collagen is completel...

Embodiment 3

[0049] A bamboo alginate functional dressing, which is composed of sodium alginate, sodium hyaluronate, collagen, bioactive glass powder and bamboo fiber, and the components are calculated in parts by weight: 1 part of sodium alginate, hyaluronic acid 0.05 parts of sodium, 0.25 parts of collagen, 4.5 parts of bioactive glass powder, and 94.2 parts of bamboo fiber.

[0050] The preparation method of described bamboo alginate functional dressing, the concrete steps of its preparation method are as follows:

[0051] (1) Dissolve 2 g of sodium alginate in 98 g of deionized water, and stir until all the sodium alginate is dissolved to obtain a sodium alginate gel, which is set aside.

[0052] (2) Dissolve 0.5 g of sodium hyaluronate in 99.5 g of deionized water, and stir until the sodium hyaluronate is completely dissolved to obtain sodium hyaluronate gel, which is set aside.

[0053] (3) Dissolve 1 g of collagen in 99 g of deionized water, and stir until the collagen is completel...

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