Phellinus igniarius and ganoderma lucidum capsules and preparation method thereof

Abstract

The invention discloses a method for preparing phellinus igniarius and ganoderma lucidum capsules. The capsules are prepared by encapsulating capsule contents according to a conventional process, wherein the capsule contents are composed of the following components in parts by weight: 5-10 parts of phellinus igniarius extract, 5-10 parts of ganoderma lucidum extract, 15-20 parts of ganoderma lucidum spore oil and 5-10 parts of beewax. The active ingredients in the phellinus igniarius and ganoderma lucidum are extracted at the greatest degree by comprehensively utilizing a unique extraction process, the effects are improved, the bioavailability is improved, the usage amount of the original medicinal materials is correspondingly reduced, and the capsules have excellent anti-fatigue effects.

Description

technical field

[0001] The invention relates to the application of Ganoderma lucidum and Phellinus linteus in the fields of pharmacy, functional food and health food, in particular to a high-content Phellinus linteus Ganoderma lucidum capsule and a preparation method thereof. Background technique

[0002] Due to work pressure, family burden and the natural aging of human organs, people often feel that their physical condition is not as good as before, and they are easily fatigued. At present, the commonly used traditional Chinese medicines for anti-fatigue in clinical practice include Acanthopanax senticosus, American ginseng, ginseng, Rhodiola rosea and Panax notoginseng.

[0003] Ganoderma lucidum, also known as "Ganoderma Lucidum", "Xiancao", "Sui Cao", is a fungus Ganoderma lucidum in the family Ganoderma lucidum of the order Ganoderma lucidum. Famous medicinal fungi, distributed in temperate regions of the northern hemisphere. It was first recorded in "Shen Nong's Mat...

Examples

Embodiment 1

[0044] Preparation of Phellinus Phellinus Extract:

[0045]Take Phellinus linteus, pulverize it, add 1:1 ethyl acetate and ethanol, heat under reflux for 40 minutes, extract 3 times, and combine the filtrates to obtain Extract I; the medicinal residues are added with 70% ethanol, heated under reflux for 40 minutes, extracted twice, and the filtrate is Merge extract II, concentrate extract II into extract, dissolve extract with 50% methanol, use ODS-C18 column to separate it, first use 8% methanol as mobile phase, get eluent I, then replace 60% methanol was used as the mobile phase to obtain eluent II, which was concentrated and dried to obtain the sample; the sample obtained by continued separation by preparative liquid chromatography: separation conditions of preparative chromatography: the chromatographic column was a semi-preparative column Lichrospher-C18; 10.0mmX250mm, 5μm , the mobile phase is A is water and B is acetonitrile, and the gradient elution procedure is as fol...

Embodiment 2

[0060] The preparation method is the same as in Example 1

[0061] It's just that the dosage ratio of Phellinus linteus extract, Ganoderma lucidum extract, Ganoderma lucidum spore oil and beeswax is 1:1:2:1.

Embodiment 3

[0063] The preparation method is the same as in Example 1

[0064] Only the dosage ratio of Phellinus linteus extract, Ganoderma lucidum extract, Ganoderma lucidum spore oil and beeswax is 2:1:3:1.

technical field

[0001] The invention relates to the application of Ganoderma lucidum and Phellinus linteus in the fields of pharmacy, functional food and health food, in particular to a high-content Phellinus linteus Ganoderma lucidum capsule and a preparation method thereof. Background technique

[0002] Due to work pressure, family burden and the natural aging of human organs, people often feel that their physical condition is not as good as before, and they are easily fatigued. At present, the commonly used traditional Chinese medicines for anti-fatigue in clinical practice include Acanthopanax senticosus, American ginseng, ginseng, Rhodiola rosea and Panax notoginseng.

[0003] Ganoderma lucidum, also known as "Ganoderma Lucidum", "Xiancao", "Sui Cao", is a fungus Ganoderma lucidum in the family Ganoderma lucidum of the order Ganoderma lucidum. Famous medicinal fungi, distributed in temperate regions of the northern hemisphere. It was first recorded in "Shen Nong's Mat...

Examples

Embodiment 1

[0044] Preparation of Phellinus Phellinus Extract:

[0045]Take Phellinus linteus, pulverize it, add 1:1 ethyl acetate and ethanol, heat under reflux for 40 minutes, extract 3 times, and combine the filtrates to obtain Extract I; the medicinal residues are added with 70% ethanol, heated under reflux for 40 minutes, extracted twice, and the filtrate is Merge extract II, concentrate extract II into extract, dissolve extract with 50% methanol, use ODS-C18 column to separate it, first use 8% methanol as mobile phase, get eluent I, then replace 60% methanol was used as the mobile phase to obtain eluent II, which was concentrated and dried to obtain the sample; the sample obtained by continued separation by preparative liquid chromatography: separation conditions of preparative chromatography: the chromatographic column was a semi-preparative column Lichrospher-C18; 10.0mmX250mm, 5μm , the mobile phase is A is water and B is acetonitrile, and the gradient elution procedure is as fol...

Embodiment 2

[0060] The preparation method is the same as in Example 1

[0061] It's just that the dosage ratio of Phellinus linteus extract, Ganoderma lucidum extract, Ganoderma lucidum spore oil and beeswax is 1:1:2:1.

Embodiment 3

[0063] The preparation method is the same as in Example 1

[0064] Only the dosage ratio of Phellinus linteus extract, Ganoderma lucidum extract, Ganoderma lucidum spore oil and beeswax is 2:1:3:1.

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