A kind of purification separation method of sucrose fatty acid ester

Abstract

The invention discloses a method for purification and separation of sucrose fatty acid ester, which comprises the following steps: a. dissolving crude sucrose fatty acid ester in an alcohol solution, heating and dissolving in a water bath to obtain a crude sucrose ester solution; b. treating sucrose ester with citric acid Adjust the pH value of the crude product solution, the pH value is between 2-4, separate layers, and discharge the lower layer of water; c, add NaCl+NaHCO accounting for 11-15% of the crude product quality of sucrose fatty acid ester to the upper organic phase 3 Stir the mixture with an electric stirrer for 10-20 minutes at 70°C, cool to 5°C, and generate a coprecipitate containing sucrose fatty acid ester and salt; d, dissolve the coprecipitate containing sucrose fatty acid ester and salt in alcohol In the solution, heat it in a water bath to dissolve, separate layers, drain the lower layer of water, and blow dry to obtain sucrose fatty acid ester. Utilizing the method of the invention to purify the sucrose fatty acid ester has high product purity and high recovery rate.

Description

technical field

[0001] The invention relates to a purification and separation method of sucrose fatty acid ester. Background technique

[0002] Sucrose fatty acid ester, abbreviated as sucrose ester, is an emulsifier with wide HLB value range, good effect, high safety and wide application range. Due to its high safety, the Food Organization of the United Nations (FAO) and the World Health Organization (WHO) approved sucrose esters as food additives in 1969 and 1980, respectively, and they have been widely used in the United States, Japan, China and EU countries. It has a wide range of application prospects in industries such as industry, pharmaceutical manufacturing, and daily chemical products. With the gradual deepening and widening of the application of sucrose esters, it is found that in many occasions, especially in the fields of medicine and cosmetics, the quality of sucrose esters is relatively high. Not only the impurity content in the sucrose ester is required to ...

Examples

Embodiment 1

[0032] Primary extraction of crude sucrose fatty acid ester: Weigh about 20 g crude sucrose fatty acid ester (accurate to 0.0001 g), place it in a 250ml beaker, add 100ml of 70% alcohol solution (V / V), heat and stir in a water bath at 70°C Dissolve, adjust the pH between 2 and 4 with citric acid (adjust until obvious stratification can be seen), and discharge the water layer (lower layer);

[0033] Secondary extraction of crude sucrose fatty acid ester: add 12% NaCl+NaHCO to the upper organic phase 3 (1:1), stir with an electric stirrer for 15 minutes at 70 °C, cool to 5 °C to generate a coprecipitate containing sucrose fatty acid ester and salt, then add 20 ml of water, heat and dissolve in a 65 °C water bath, and discharge the water layer ( lower layer) to obtain sucrose fatty acid ester, air-dried at 35°C, and sealed for storage.

Embodiment 2

[0035] Primary extraction of crude sucrose fatty acid ester: Weigh about 20 g crude sucrose fatty acid ester (accurate to 0.0001 g), place it in a 250ml beaker, add 100ml of 70% alcohol solution (V / V), heat and stir in a water bath at 70°C Dissolve, adjust the pH between 2 and 4 with citric acid (adjust until obvious stratification can be seen), and discharge the water layer (lower layer);

[0036] Secondary extraction of crude sucrose fatty acid ester: add 13% NaCl+NaHCO to the upper organic phase 3 (1:1), stir with an electric stirrer for 15 minutes at 70 °C, cool to 5 °C to generate a coprecipitate containing sucrose fatty acid ester and salt, then add 20 ml of water, heat and dissolve in a 65 °C water bath, and discharge the water layer ( lower layer) to obtain sucrose fatty acid ester, air-dried at 35°C, and sealed for storage.

Embodiment 3

[0038] Primary extraction of crude sucrose fatty acid ester: Weigh about 20 g crude sucrose fatty acid ester (accurate to 0.0001 g), place it in a 250ml beaker, add 100ml of 70% alcohol solution (V / V), heat and stir in a water bath at 70°C Dissolve, adjust the pH between 2 and 4 with citric acid (adjust until obvious stratification can be seen), and discharge the water layer (lower layer);

[0039] Secondary extraction of crude sucrose fatty acid ester: add 14% NaCl+NaHCO to the upper organic phase 3 (1:1), stir with an electric stirrer for 15 minutes at 70 °C, cool to 5 °C to generate a coprecipitate containing sucrose fatty acid ester and salt, then add 20 ml of water, heat and dissolve in a 65 °C water bath, and discharge the water layer ( lower layer) to obtain sucrose fatty acid ester, air-dried at 35°C, and sealed for storage.

technical field

[0001] The invention relates to a purification and separation method of sucrose fatty acid ester. Background technique

[0002] Sucrose fatty acid ester, abbreviated as sucrose ester, is an emulsifier with wide HLB value range, good effect, high safety and wide application range. Due to its high safety, the Food Organization of the United Nations (FAO) and the World Health Organization (WHO) approved sucrose esters as food additives in 1969 and 1980, respectively, and they have been widely used in the United States, Japan, China and EU countries. It has a wide range of application prospects in industries such as industry, pharmaceutical manufacturing, and daily chemical products. With the gradual deepening and widening of the application of sucrose esters, it is found that in many occasions, especially in the fields of medicine and cosmetics, the quality of sucrose esters is relatively high. Not only the impurity content in the sucrose ester is required to ...

Examples

Embodiment 1

[0032] Primary extraction of crude sucrose fatty acid ester: Weigh about 20 g crude sucrose fatty acid ester (accurate to 0.0001 g), place it in a 250ml beaker, add 100ml of 70% alcohol solution (V / V), heat and stir in a water bath at 70°C Dissolve, adjust the pH between 2 and 4 with citric acid (adjust until obvious stratification can be seen), and discharge the water layer (lower layer);

[0033] Secondary extraction of crude sucrose fatty acid ester: add 12% NaCl+NaHCO to the upper organic phase 3 (1:1), stir with an electric stirrer for 15 minutes at 70 °C, cool to 5 °C to generate a coprecipitate containing sucrose fatty acid ester and salt, then add 20 ml of water, heat and dissolve in a 65 °C water bath, and discharge the water layer ( lower layer) to obtain sucrose fatty acid ester, air-dried at 35°C, and sealed for storage.

Embodiment 2

[0035] Primary extraction of crude sucrose fatty acid ester: Weigh about 20 g crude sucrose fatty acid ester (accurate to 0.0001 g), place it in a 250ml beaker, add 100ml of 70% alcohol solution (V / V), heat and stir in a water bath at 70°C Dissolve, adjust the pH between 2 and 4 with citric acid (adjust until obvious stratification can be seen), and discharge the water layer (lower layer);

[0036] Secondary extraction of crude sucrose fatty acid ester: add 13% NaCl+NaHCO to the upper organic phase 3 (1:1), stir with an electric stirrer for 15 minutes at 70 °C, cool to 5 °C to generate a coprecipitate containing sucrose fatty acid ester and salt, then add 20 ml of water, heat and dissolve in a 65 °C water bath, and discharge the water layer ( lower layer) to obtain sucrose fatty acid ester, air-dried at 35°C, and sealed for storage.

Embodiment 3

[0038] Primary extraction of crude sucrose fatty acid ester: Weigh about 20 g crude sucrose fatty acid ester (accurate to 0.0001 g), place it in a 250ml beaker, add 100ml of 70% alcohol solution (V / V), heat and stir in a water bath at 70°C Dissolve, adjust the pH between 2 and 4 with citric acid (adjust until obvious stratification can be seen), and discharge the water layer (lower layer);

[0039] Secondary extraction of crude sucrose fatty acid ester: add 14% NaCl+NaHCO to the upper organic phase 3 (1:1), stir with an electric stirrer for 15 minutes at 70 °C, cool to 5 °C to generate a coprecipitate containing sucrose fatty acid ester and salt, then add 20 ml of water, heat and dissolve in a 65 °C water bath, and discharge the water layer ( lower layer) to obtain sucrose fatty acid ester, air-dried at 35°C, and sealed for storage.

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