A blood sampling device with magnetic stirring function

Abstract

The present invention discloses a blood collector with a magnetic stirring function, comprising a blood collector body and a magnetic stirring body arranged in the inner cavity of the blood collector body, wherein the magnetic stirring body is used for reciprocating stirring motion along the inner cavity of the blood collector body under the action of a changing magnetic field. The blood collector with a magnetic stirring function provided by the present invention stirs evenly, is easy to use, and effectively avoids the phenomenon of coagulation caused by uneven mixing of blood and anticoagulant during the blood collection process.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a blood collection device with a magnetic stirring function. Background Technology

[0002] Currently, existing blood collection devices are coated with anticoagulant on their inner walls. After blood collection, the device is rubbed back and forth and inverted to mix the blood and anticoagulant. Heparin is the most commonly used anticoagulant. Heparin binds to antithrombin III, thereby blocking clotting. Ideally, the dead space air in a blood gas sample should be less than 5%. Under these air-isolated conditions, mixing the anticoagulant is very difficult; therefore, blood gas sample collection requires a relatively high concentration of heparin for anticoagulation. The IFCC (International Federation for Clinical Chemistry) recommends a final appropriate heparin concentration of 50 IU / mL. However, high concentrations of heparin will bind to free calcium ions in the blood, as well as other vital signs such as potassium ions. + Cl － Ions, etc., can cause these test results to be lower than expected. Existing blood collection devices typically use a low concentration of heparin in conjunction with a stirrer to mix the blood and prevent it from clotting.

[0003] Currently, blood collection devices contain mixing balls, and the mixing relies mainly on continuous rubbing and repeated inversion of the device to agitate the blood. However, due to the small size of the balls, the mixing effect is not ideal. For micro-volume blood collection devices, metal balls are added for vibration and agitation. However, for large-capacity devices, the effect is not ideal, and multiple rubbing of the device is still required. Alternatively, a separate mixing device can be used, which provides better mixing, but is bulky and inconvenient. Furthermore, manual pre-mixing is still required before using the device, which can easily cause blood clotting.

[0004] Therefore, how to solve the problem of uneven mixing of blood and anticoagulant has become a technical problem that needs to be solved by those skilled in the art. Summary of the Invention

[0005] The purpose of this invention is to provide a blood collection device with magnetic stirring function. This device can stir blood evenly, is easy to use, and effectively avoids the phenomenon of coagulation caused by uneven mixing of blood and anticoagulant during the blood collection process.

[0006] To achieve the above objectives, the present invention provides a blood collection device with a magnetic stirring function, comprising a blood collection device body and a magnetic stirring body disposed in the inner cavity of the blood collection device body, wherein the magnetic stirring body is used to reciprocate stirring along the inner cavity of the blood collection device body under the action of a changing magnetic field.

[0007] Optionally, the magnetic stirrer includes a magnetic induction mechanism and a stirring mechanism, wherein the magnetic induction mechanism is embedded in the stirring mechanism.

[0008] Optionally, the stirring mechanism includes coaxially arranged stirring blades and an impeller disposed around all of the stirring blades.

[0009] Optionally, the magnetic induction mechanism is a permanent magnet.

[0010] Optionally, the magnetic induction mechanism is a closed coil.

[0011] Optionally, the impeller has an annular groove in its circumference, and the magnetic induction mechanism is embedded in the annular groove.

[0012] Optionally, all the blades are tilted in the same direction.

[0013] Optionally, it also includes a magnetic field generating mechanism for generating a changing magnetic field, wherein the magnetic field generating mechanism is an electromagnetic generating mechanism that excites a periodically changing magnetic field by a periodically changing current.

[0014] Optionally, the blood collection device body is a syringe, and the diameter of the magnetic stirrer is smaller than the inner diameter of the syringe.

[0015] Compared to the aforementioned background technology, the blood collection device with magnetic stirring function provided by this invention includes a blood collection device body and a magnetic stirring element disposed within the inner cavity of the blood collection device body. By placing the blood collection device body in a changing magnetic field environment, the magnetic stirring element is subjected to the changing magnetic field, generating changing forces (including attraction and repulsion) between itself and the changing magnetic field. This causes the magnetic stirring element to reciprocate within the inner cavity of the blood collection device body, effectively mixing the blood and anticoagulant thoroughly and evenly. Furthermore, once the blood collection device body is in place, no manual shaking or vibration is required, making it very convenient. Moreover, the magnetic stirring element does not require mechanical connection to the outside environment, which helps maintain the airtight and oxygen-free environment of the blood collection device body.

[0016] For example, after the blood collection device is vertically fixed, a changing magnetic field generates varying magnetic attraction or repulsion on the magnetic stirrer. When the sum of the attraction or repulsion and the buoyancy force on the magnetic stirrer exceeds the weight of the magnetic stirrer and the resistance of the blood, the magnetic stirrer moves upward along the inner cavity of the blood collection device; conversely, it moves downward along the inner cavity. This reciprocating upward and downward movement thoroughly stirs the blood and anticoagulant within the blood collection device, effectively preventing blood clotting. By appropriately setting the placement of the blood collection device and changing the strength and direction of the magnetic field, the direction and speed of the magnetic stirrer can be altered as needed. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0018] Figure 1 This is a structural diagram of a blood collection device with magnetic stirring function provided in an embodiment of the present invention;

[0019] Figure 2 for Figure 1 Schematic diagram of a magnetic stirrer;

[0020] Figure 3 for Figure 1 A schematic diagram of another type of magnetic stirrer;

[0021] Figure 4 for Figure 2 or Figure 3 A schematic diagram of the stirring mechanism.

[0022] in:

[0023] 1-Blood collection device body, 2-Magnetic stirring body, 21-Magnetic induction mechanism, 211-Closed coil, 212-Permanent magnet, 22-Stirring mechanism, 221-Blade, 222-Impeller. Detailed Implementation

[0024] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0025] To enable those skilled in the art to better understand the present invention, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0026] Please refer to Figures 1 to 4 , Figure 1 This is a structural diagram of a blood collection device with magnetic stirring function provided in an embodiment of the present invention. Figure 2 for Figure 1 A schematic diagram of the magnetic stirrer 2. Figure 3 for Figure 1 A schematic diagram of another type of magnetic stirrer 2. Figure 4 for Figure 2 or Figure 3 A schematic diagram of the stirring mechanism 22.

[0027] The blood collection device with magnetic stirring function provided by this invention includes a blood collection device body 1 and a magnetic stirrer 2 disposed in the inner cavity of the blood collection device body 1. After blood collection is completed, the blood collection device is placed in a changing magnetic field. Under the action of the changing magnetic field, the magnetic stirrer 2 generates magnetic attraction or repulsion. With the help of attraction or repulsion, it reciprocates along the inner cavity of the blood collection device body 1 in a preset direction, thoroughly stirring the blood and anticoagulant in the inner cavity of the blood collection device body 1 to prevent blood coagulation. The entire process does not require manual shaking of the blood collection device, nor does it require the magnetic stirrer 2 to be mechanically connected to an external power mechanism through the blood collection device body 1, improving the convenience of using the blood collection device and helping to maintain a low-oxygen or even oxygen-free environment in the blood.

[0028] The blood collection device with magnetic stirring function provided by the present invention will be described in more detail below with reference to the accompanying drawings and specific embodiments.

[0029] In the present invention as provided Figure 1 In the specific embodiment shown, the blood collection device body 1 is illustrated using a syringe as an example. The magnetic stirrer 2 is disposed inside the syringe barrel, and the diameter of the magnetic stirrer 2 is slightly smaller than the inner diameter of the syringe barrel. After blood collection is completed, the syringe can be vertically fixed in a changing magnetic field. Under the action of the magnetic field, the magnetic stirrer 2 is subjected to the magnetic force of the changing magnetic field. For example, when the syringe is fixed above the magnetic field, when the sum of the magnetic repulsion force and the magnetic force experienced by the magnetic stirrer 2 is greater than the sum of the weight of the magnetic stirrer 2 and the upward resistance, the magnetic stirrer 2 will float up along the syringe barrel. By changing the direction, intensity, and rate of change of the magnetic field, the magnetic force experienced by the magnetic stirrer 2 can be changed, thereby controlling the movement direction and speed of the magnetic stirrer 2 along the inner cavity of the blood collection device body 1, and thoroughly mixing the collected blood with the anticoagulant added to the blood to prevent blood coagulation.

[0030] The blood collection device body 1 can also be made of various shapes and specifications as needed, as long as the size of the magnetic stirrer 2 matches that of the blood collection device body 1. This size matching mainly refers to ensuring that the diameter of the magnetic stirrer 2 is not too small relative to the inner cavity of the blood collection device body 1, thus preventing the magnetic stirrer 2 from failing to achieve its mixing function. It should be noted that the core of this invention lies in using a changing magnetic field to drive the magnetic stirrer 2 to experience changing magnetic attraction or repulsion. Under the combined action of attraction, gravity, buoyancy, and resistance, it reciprocates along the inner cavity of the stirrer body to achieve mixing. The magnetic stirrer 2 can be configured not only as shown in the example... Figure 1 The set shown can also be set into multiple sets depending on the size specifications.

[0031] To provide a changing magnetic field, a magnetic attraction or repulsion force is generated to drive the magnetic stirrer 2. This invention also provides a magnetic field generating mechanism. Specifically, the magnetic field generating mechanism is an electromagnetic generating mechanism, including an electromagnetic coil and a current input control mechanism connected to the electromagnetic coil. The current input control mechanism is mainly connected to an external power source to provide a periodically changing current, such as a sinusoidal alternating current, to the electromagnetic coil. The electromagnetic coil and the current input control mechanism are sealed in an insulating box. The upper surface of the insulating box can be provided with a platform or fixing frame, fixing clamp, or other mechanism for placing the blood collection device body 1.

[0032] The current input control mechanism generates a periodically changing magnetic field in space by inputting a periodically changing current into the electromagnetic coil. This causes the magnetic stirrer 2, which is placed in the changing magnetic field, to be subjected to a periodically changing magnetic force (attraction or repulsion), thereby achieving a periodic reciprocating stirring motion along the inner cavity of the blood collection device.

[0033] Please refer to Figures 2 to 4 In the above embodiment, the magnetic stirrer 2 mainly includes a magnetic induction mechanism 21 and a stirring mechanism 22, with the magnetic induction mechanism 21 embedded in the stirring mechanism 22. When the changing magnetic field and the magnetic force generated between the magnetic induction mechanism 21 act on the magnetic induction mechanism 21, causing it to move, the magnetic induction mechanism 21, being embedded in the stirring mechanism 22, drives the stirring mechanism 22 to reciprocate and stir.

[0034] Specifically, the stirring mechanism 22 can be configured as a stirring mechanism 22 including stirring blades 221 and impeller 222. All blades 221 are coaxially arranged, and the impeller 222 is arranged circumferentially on the blades 221 and connected to the blades 221 through the blade tips. An annular groove is formed on the outer periphery of the impeller 222, and the magnetic induction mechanism 21 is embedded in the annular groove.

[0035] Furthermore, all the blades 221 are inclined in the same direction. The inclined setting mentioned here mainly refers to the plane defined by the impeller 222. In this way, when the magnetic induction mechanism 21 is driven by magnetic attraction or force to drive the stirring mechanism 22 to reciprocate, the blood acts on the surface of the inclined blades 221, generating a rotational driving force for the blades 221 and the impeller 222.

[0036] In other words, by using the inclined blades 221 to make the stirring mechanism 22 reciprocate under the drive of the magnetic induction mechanism 21, the stirring mechanism 22 can also rotate and stir at the same time, which further improves the mixing effect of blood and anticoagulant and avoids blood clotting.

[0037] In the above embodiments, the magnetic induction mechanism 21 mainly includes the following two forms, one of which is as follows: Figure 2 The closed coil 211 shown is another type, as shown in the figure. Figure 3The permanent magnet 212 shown.

[0038] When the magnetic induction mechanism 21 is a closed coil 211, the working mechanism of the magnetic stirrer 2 is as follows: the magnetic field generating mechanism excites a periodically changing magnetic field, and the closed coil 211, which is embedded in the periphery of the impeller 222, induces a current under the action of the periodically changing magnetic field. The direction of the induced magnetic field generated by the induced current is always opposite to the direction of the change of the original magnetic field strength. Through the interaction between the original magnetic field and the induced magnetic field, a magnetic attraction or magnetic repulsion is generated, which drives the magnetic induction mechanism 21 to reciprocate relative to the magnetic field generating mechanism. At the same time as the magnetic induction mechanism 21 drives the stirring mechanism 22 to reciprocate, the stirring mechanism 22 rotates under the action of the inclined blade 221, which fully mixes the blood and anticoagulant evenly.

[0039] Obviously, the annular groove and the closed coil 211 can not only provide... Figure 2 The set shown can be flexibly configured into multiple sets depending on the thickness of the impeller 222.

[0040] When the magnetic induction mechanism 21 is a permanent magnet 212, the magnetic field generated by the magnetic field generating mechanism interacts with the magnetic field of the permanent magnet 212, driving the magnetic induction mechanism 21 to reciprocate along the inner cavity of the blood collection device body 1. At the same time, the force on the inclined impeller 222 drives the stirring mechanism 22 to rotate, so as to fully mix the blood and anticoagulant evenly.

[0041] Similarly, when the magnetic induction mechanism 21 is a permanent magnet 212, the permanent magnet 212 can be configured in multiple sets. Moreover, the permanent magnet 212 does not need to be configured as a closed ring, but can be configured as multiple sets of block magnets symmetrically arranged around the impeller 222 to ensure that the impeller 222 is subjected to a uniform driving force.

[0042] By applying an anticoagulant to the surface of the magnetic stirrer 2, the magnetic stirrer 2 can be driven to reciprocate within the blood collection device body 1 after blood collection, so that the anticoagulant on the surface of the magnetic stirrer 2 is fully mixed with the blood.

[0043] It should be noted that in this specification, relational terms such as first and second are used only to distinguish one entity from several other entities, and do not necessarily require or imply any such actual relationship or order between these entities.

[0044] The above provides a detailed description of the blood collection device with magnetic stirring function provided by the present invention. Specific examples have been used to illustrate the principles and implementation methods of the invention. The descriptions of the embodiments above are merely for the purpose of helping to understand the method and core ideas of the present invention. It should be noted that those skilled in the art can make various improvements and modifications to the present invention without departing from its principles, and these improvements and modifications also fall within the protection scope of the claims of the present invention.

Claims

1. A blood sampling device with magnetic stirring function, characterized in that: The invention comprises a blood collector body (1) and a magnetic stirring body (2) arranged in the inner cavity of the blood collector body (1), wherein the magnetic stirring body (2) is used for reciprocating stirring motion along the inner cavity of the blood collector body (1) under the action of a changing magnetic field; the magnetic stirring body (2) and the blood collector body (1) are coaxially arranged; the diameter of the magnetic stirring body (2) is slightly smaller than the inner diameter of the blood collector body (1); The magnetic stirring body (2) comprises a magnetic induction mechanism (21) and a stirring mechanism (22), wherein the magnetic induction mechanism (21) is embedded in the stirring mechanism (22); The stirring mechanism (22) comprises stirring blades (221) arranged coaxially and impellers (222) arranged around all the stirring blades (221); all the blades (221) are arranged to be inclined in the same direction, so as to generate a rotational driving force for the stirring blades (221) and the impellers (222); It also includes a magnetic field generating mechanism for generating a changing magnetic field. The magnetic field generating mechanism is an electromagnetic generating mechanism that excites a periodically changing magnetic field with a periodically changing current, thereby realizing a periodic reciprocating stirring motion along the inner cavity of the blood collector.

2. The blood sampling device with magnetic stirring function according to claim 1, characterized in that: The magnetic force induction mechanism (21) is a permanent magnet (212).

3. The blood sampling device with magnetic stirring function according to claim 1, characterized in that: The magnetic force induction mechanism (21) is a closed coil (211).

4. The blood sampling device with magnetic stirring function according to claim 1, characterized in that: An annular groove is provided in the circumference of the impeller (222), and the magnetic induction mechanism (21) is installed in the annular groove.

5. The blood sampling device with magnetic stirring function according to claim 1, characterized in that: The blood sampling device body (1) is a syringe.

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