Production process of benzoin

Abstract

The invention discloses a production process of benzoin, and relates to the technical field of benzoin. The production process comprises the following process steps: S1, preparing raw materials in proportion; S2, according to the proportion of the raw materials in step S1, firstly pumping benzaldehyde into a reaction kettle, then adding tap water, then starting stirring, then adding tetrabutylammonium bromide, finally adding a sodium cyanide solution, and heating to the internal temperature of 100 + / -5 DEG C; and S3, carrying out a thermal insulation reaction for 1.5-4 h until a large amount of solids are separated out, ending the reaction, and naturally cooling to 5-10 DEG C to obtain the benzoin through the four steps. The preparation method disclosed by the invention has the advantagesof improving the yield and saving the cost.

Description

technical field

[0001] The invention relates to the technical field of benzoin, in particular to a production process of benzoin. Background technique

[0002] Benzoin is also called benzoin. Benzoin is an important chemical raw material, and can also be used as a pharmaceutical intermediate, such as the synthesis of antiepileptic drug diphenylhydantoin; it can also be used in the synthesis of benzoin dimethyl ether, photosensitizer benzoin ether, and benzil.

[0003] The synthetic technique of existing benzoin discloses a kind of preparation method of benzoin product as authorized announcement number is the Chinese invention patent of CN103288609B, take benzaldehyde as reaction raw material, sodium cyanide or potassium cyanide as catalyst, water as reaction solvent, select A high-efficiency cationic surfactant, a phase transfer catalyst, a dispersant, and an inorganic salt are added to the reaction mixture system, the temperature is raised to 60-70°C, and the reaction is k...

Examples

preparation example Construction

[0052]Sodium carbonate composite particles are prepared by the following steps:

[0053] Step 1: Mix the solutions of calcium chloride and sodium lauryl sulfate evenly in proportion, and control the stirring speed to be 200 revolutions / second when mixing;

[0054] Step 2: Then add sodium carbonate solution in proportion, and maintain the rotating speed to stir;

[0055] Step 3: centrifuging the mixed solution after stirring to obtain solid A;

[0056] Step 4: Soak solid A in sodium glycinate solution for 1 hour to obtain solid B;

[0057] Step 5: drying the soaked fixed B to obtain sodium carbonate composite particles.

Embodiment 1

[0060] The difference between embodiment 17~20 and embodiment 1 is that each component in the sodium carbonate composite particle counts the following table by weight.

[0061] Example Sodium carbonate calcium chloride Sodium dodecyl sulfate sodium glycinate Example 17 27.5 27.5 27.5 17.5 Example 18 35 25 25 15 Example 19 42.5 22.5 22.5 12.5 Example 20 50 20 20 10

[0062] The difference between Embodiments 20-23 and Embodiment 1 is that the parameters in steps S2 and S3 are listed in the following table.

[0063]

technical field

[0001] The invention relates to the technical field of benzoin, in particular to a production process of benzoin. Background technique

[0002] Benzoin is also called benzoin. Benzoin is an important chemical raw material, and can also be used as a pharmaceutical intermediate, such as the synthesis of antiepileptic drug diphenylhydantoin; it can also be used in the synthesis of benzoin dimethyl ether, photosensitizer benzoin ether, and benzil.

[0003] The synthetic technique of existing benzoin discloses a kind of preparation method of benzoin product as authorized announcement number is the Chinese invention patent of CN103288609B, take benzaldehyde as reaction raw material, sodium cyanide or potassium cyanide as catalyst, water as reaction solvent, select A high-efficiency cationic surfactant, a phase transfer catalyst, a dispersant, and an inorganic salt are added to the reaction mixture system, the temperature is raised to 60-70°C, and the reaction is k...

Examples

preparation example Construction

[0052]Sodium carbonate composite particles are prepared by the following steps:

[0053] Step 1: Mix the solutions of calcium chloride and sodium lauryl sulfate evenly in proportion, and control the stirring speed to be 200 revolutions / second when mixing;

[0054] Step 2: Then add sodium carbonate solution in proportion, and maintain the rotating speed to stir;

[0055] Step 3: centrifuging the mixed solution after stirring to obtain solid A;

[0056] Step 4: Soak solid A in sodium glycinate solution for 1 hour to obtain solid B;

[0057] Step 5: drying the soaked fixed B to obtain sodium carbonate composite particles.

Embodiment 1

[0060] The difference between embodiment 17~20 and embodiment 1 is that each component in the sodium carbonate composite particle counts the following table by weight.

[0061] Example Sodium carbonate calcium chloride Sodium dodecyl sulfate sodium glycinate Example 17 27.5 27.5 27.5 17.5 Example 18 35 25 25 15 Example 19 42.5 22.5 22.5 12.5 Example 20 50 20 20 10

[0062] The difference between Embodiments 20-23 and Embodiment 1 is that the parameters in steps S2 and S3 are listed in the following table.

[0063]

Images