A drying device for producing fenofibrate capsules with temperature control function

By designing a drying equipment with temperature control function, combined with the feeding mechanism, hot air fan, vibration motor and temperature adjustment mechanism, the quality problem caused by inconsistent moisture content during the drying process of Fenofibrate capsules is solved, and automatic adjustment of drying is achieved The dry temperature and the effect of dispersing agglomerated particles improve the drying quality and finished product quality.

CN117989822BActive Publication Date: 2025-02-14SHANG HAI HENG SHAN YAO YE YOU XIAN GONG SI
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Patent Information

Application Number
CN202410042460.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-01-11
Publication Date
2025-02-14
Estimated Expiration
2044-01-11

AI Technical Summary

Technical Problem

During the drying process of fenofibrate capsules, due to the inconsistent moisture content of the raw materials, particles with low moisture content after drying at the same temperature are prone to brittlement and crushing, affecting the quality of the medicine.

Method used

A drying equipment with temperature control function was designed. The feeding mechanism was quantified. The hot air fan provided the hot air flow, and the vibrating motor generated directional vibration. The drying temperature was automatically adjusted according to the moisture content of the drug particles, and The agglomerated particles are dispersed by a dispersion mechanism to ensure uniform drying and finished product quality.

Benefits of technology

It realizes automatic adjustment of the drying temperature according to the moisture content of the drug particles, avoids excessive drying and embrittlement of particles with low moisture content, and improves the drying quality and the finished product quality of the drug.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a drying device for producing fenofibrate capsules with a temperature control function. The drying device comprises a frame, a hot air blower, a feeding mechanism and a drying bin. The hot air blower is tightly connected to the frame, the drying bin is communicated with an air outlet of the hot air blower, the hot air blower is used to provide heat for the drying bin, the feeding mechanism is communicated with the drying bin, the feeding mechanism is used to quantitatively feed the materials, a vibration motor is arranged on the drying bin, the frame provides stable support for each mechanism to ensure stable operation of the device, the medicine particles to be dried are quantitatively added into the drying bin through the feeding mechanism for drying, the hot air blower is started to provide a stable hot air flow for the drying bin, the vibration motors on both sides of the drying bin are started, the drying bin generates directional and uniform vibration under the exciting force of the vibration motor, thereby transporting the medicine particles in the drying bin to make them evenly dried.
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Description

Technical Field

[0001] The invention relates to the technical field of drying, in particular to drying equipment for producing fenofibrate capsules with a temperature control function. Background Art

[0002] Fenofibrate capsules are a common drug used clinically to adjust blood lipid levels. The preparation method is: add fenofibrate, lactose and other raw materials into a mixer and mix them, then add the mixed materials into a wet granulator to obtain soft material particles with a high moisture content, and then dry the particles. After drying, the particles are filled into capsules to make the finished product.

[0003] Drying equipment is a kind of equipment used to remove excess moisture from items or adjust the moisture content of items. Generally, high temperature or vacuum is used to remove moisture from items to achieve the drying effect. Pharmaceutical particles are generally dried in a fluidized bed, and high-temperature airflow passes through the material to take away the moisture. However, during the drying process, because the moisture content of the raw materials is inconsistent, if the same temperature is used for drying, the particles with low moisture content will become brittle and easy to break after drying, which will affect the quality of the medicine. Summary of the invention

[0004] The object of the present invention is to provide a drying device for producing fenofibrate capsules with a temperature control function to solve the problems raised in the above-mentioned background technology.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: the drying equipment includes a frame, a hot air blower, a feeding mechanism, and a drying bin. The hot air blower is firmly connected to the frame, the drying bin is connected to an air outlet of the hot air blower, the hot air blower is used to provide heat to the drying bin, the feeding mechanism is connected to the drying bin, the feeding mechanism is used for quantitative feeding, and a vibration motor is provided on the drying bin.

[0006] The frame provides stable support for each mechanism to ensure the stable operation of the equipment. The pharmaceutical particles that need to be dried are quantitatively added into the drying bin for drying through the feeding mechanism. The hot air blower is started to provide a stable hot air flow for the drying bin. The vibration motors on both sides of the drying bin are started. The drying bin generates directional and uniform vibration under the exciting force of the vibration motor, thereby transporting the pharmaceutical particles in the drying bin for uniform drying.

[0007] Furthermore, the drying bin includes a bin body and a porous partition. The bin body is firmly connected to the frame, and the porous partition is firmly connected to the bin body. The bin body is provided with an air inlet, a feed port, an exhaust port, and a discharge port. The air inlet is connected to the air outlet of the hot air blower, the feed port is connected to the feeding mechanism, and the exhaust port is used to discharge the hot and humid gas generated by drying.

[0008] The bin body and porous partitions are made of stainless steel to ensure the hygiene and safety of the drying process. The frame provides stable support for the bin body. The hot air flow from the hot air blower flows into the bin body through the air inlet. After entering the bin body, the drug particles will fall onto the porous partition at the bottom of the bin body. The hot air flow blows upward from the bottom of the porous partition, causing the drug particles to move on the porous partition and be suspended under the blowing of the hot air flow, which promotes the mixing of the drug particles and the hot air flow, allowing the drug particles to fully contact the hot air flow, and transfer heat and moisture between the two, thereby drying the drug particles and gradually moving toward the discharge port under the action of the vibration motor. The hot and humid gases generated during the drying process are discharged through the exhaust port.

[0009] Furthermore, the feeding mechanism includes a shell, a star wheel, and a drive motor. The shell is connected to the drying bin, the star wheel is rotationally connected to the shell, the drive motor is tightly connected to the shell, and the output shaft of the drive motor is transmission-connected to the star wheel.

[0010] The shell is fixed on the drying bin to provide a stable working platform for the driving motor. The output shaft of the driving motor transmits power to the star wheel through a belt, thereby driving the star wheel to rotate in the shell, thereby dividing the drug particles entering the feeding mechanism into parts of the same volume, and driven by the rotating star wheel, gradually adding them into the drying bin for drying, so that the feed flow rate remains stable, ensuring the drying effect.

[0011] Furthermore, a temperature regulating mechanism and a dispersing mechanism are also provided in the bin body. The temperature regulating mechanism is located in the air inlet, and the dispersing mechanism is located in the discharge port.

[0012] The dryness and humidity of the drug particles obtained by the wet granulator will have a certain deviation, so the moisture content of the drug particles added to the bin for drying will be different. If the same temperature is used for drying, the material with low moisture content will be too dry after drying and easily broken, affecting the quality of the drug. Therefore, a temperature regulating mechanism is required to automatically adjust the drying temperature according to the moisture content of the added drug particles to ensure the drying quality. The temperature regulating mechanism adjusts the drying temperature by adjusting the air intake of the air inlet. The moist drug particles will move along the porous partition during drying and are prone to agglomeration. The agglomerated drug powder particles are dispersed by the dispersion mechanism to ensure the quality of the finished product.

[0013] Furthermore, the temperature regulating mechanism includes a detection component and an adjustment component. The detection component is electrically connected to the adjustment component. The detection component is firmly connected to the bin body. The detection component is located directly below the feed port. The adjustment component is firmly connected to the bin body. The adjustment component is located in the air inlet.

[0014] The detection component is used to detect the moisture content of the drug particles, and then control the action of the adjustment component according to the measured data to adjust the drying temperature. The feeding mechanism divides the drug particles into components of the same volume and adds them into the bin for drying in sequence. For the same volume of drug powder particles, the higher the moisture content and the heavier the weight, the greater the impact force on the detection component when falling into the bin. The detection component is set just below the feed port to facilitate the detection of the impact force of the drug particles when they fall. The greater the impact force, the higher the moisture content. The drying temperature is then adjusted by adjusting the air intake volume through the adjustment component located in the air inlet.

[0015] Furthermore, the detection component includes a base, a pressure strain gauge, and a movable plate. The base is tightly connected to the chamber body, the pressure strain gauge is tightly connected to the base, the pressure strain gauge is externally connected to a detection power supply, the pressure strain gauge and the detection power supply constitute a detection circuit, the detection circuit is electrically connected to the adjustment group, the movable plate is slidably connected to the base, and the movable plate abuts against the pressure strain gauge.

[0016] During the falling process, the drug particles will collide with the movable plate, thereby pushing the movable plate to slide downward on the base, causing the pressure strain gauge to be compressed. The resistance of the compressed pressure strain gauge will change and is proportional to the pressure received. The detection power supply and the pressure strain gauge are energized to form a detection circuit. The detection circuit can detect the change in the resistance of the pressure strain gauge to determine the impact force of the drug particles on the movable plate, and then determine the moisture content of the drug particles. The higher the moisture content, the greater the impact force, and the action of the adjustment component is controlled according to this electrical signal.

[0017] Furthermore, the adjustment component includes a rotating blade, a rotating shaft, a transmission gear, a rack, and an electric push rod. The rotating shaft is rotatably connected to the warehouse body, the rotating blade is firmly connected to the rotating shaft, the transmission gear is firmly connected to the rotating shaft, a movable groove is provided on the warehouse body, the rack is slidably connected to the movable groove, the output end of the electric push rod is transmission-connected to the rack, the electric push rod is firmly connected to the warehouse body, and the transmission gear is meshed with the rack.

[0018] The adjusting component adjusts the air intake by adjusting the angle of the rotating blades. When the rotating blades are parallel to each other, the air intake is maximum and the drying temperature is highest. According to the moisture content of the drug particles measured by the detection component, the angle of the rotating blades is adjusted by the electric push rod. The electric push rod moves to push the rack to slide along the movable groove, thereby driving the transmission gear meshing with the rack to rotate, and then driving the rotating shaft to rotate along the bin body, so that the angle of the rotating blades changes. The higher the moisture content of the drug particles, the more the angles between the rotating blades tend to be parallel, thereby realizing the function of automatically adjusting the drying temperature according to the moisture content of the drug particles and improving the drying quality.

[0019] Furthermore, the vertical cross-section of the discharge port is an inverted trapezoid, and the dispersion mechanism includes a rotating motor, a driving roller, a redirecting roller, a separation belt, and an air jet head. The rotating motor is firmly connected to the bin body, the output end of the rotating motor is transmission-connected to the driving roller, the driving roller is rotationally connected to the bin body, the separation belt is transmission-connected to the driving roller, the separation belt is rotationally connected to the redirecting roller, the air jet head is firmly connected to the bin body, the air outlet end of the air jet head faces the discharge port, and the movement direction of the separation belt is opposite to the movement direction of the material.

[0020] The discharge path of the drug particles is constrained by setting the vertical section of the discharge port to an inverted trapezoid, and the contracted discharge port can block the drug particles that are clustered together, so that the dispersion mechanism can disperse the clusters. The rotating motor is the main power source of the dispersion mechanism. The rotating motor is started to drive the drive roller to rotate, thereby driving the separation belt to rotate. The redirecting roller is used to constrain the moving trajectory of the separation belt. The airflow ejected by the nozzle gives a driving force to the drug particles, so that the drug particles hit the separation belt. Because the movement direction of the separation belt is opposite to the movement direction of the material, when the clustered drug particles hit the separation belt, the impact force generated by the collision and the friction force on the drug particles generated by the rotation of the separation belt will peel off the clustered drug particles, thereby dispersing the clustered particles, and the airflow ejected by the nozzle can also cool the drug particles, which is convenient for subsequent packaging processing.

[0021] Furthermore, the separation belt is provided with a protrusion.

[0022] In order to increase the friction between the drug particles and the separation belt and improve the peeling and dispersion effect, protrusions are provided on the separation belt.

[0023] Compared with the prior art, the beneficial effects achieved by the present invention are as follows: materials of equal volume are transported to the drying bin for drying through the feeding mechanism; for medicine powder particles of the same volume, the higher the moisture content and the heavier the weight, the greater the impact force on the detection component when falling into the bin; the moisture content of the medicine particles is determined by the cooperation of the pressure strain gauge and the movable plate, and the air intake is adjusted by adjusting the angle of the rotating blades through the electric push rod, thereby realizing the function of automatically adjusting the drying temperature according to the moisture content of the medicine particles and improving the drying quality; the discharge path of the medicine particles is constrained by setting the vertical section of the discharge port to an inverted trapezoid, and the contracted discharge port can block the aggregation The drug particles that are gathered together are dispersed by the dispersing mechanism. The rotating motor is started to drive the driving roller to rotate, thereby driving the separation belt to rotate. The airflow ejected from the nozzle gives a driving force to the drug particles, causing the drug particles to hit the separation belt. Because the movement direction of the separation belt is opposite to the movement direction of the material, when the drug particles that are gathered together hit the separation belt, the impact force generated by the collision and the friction force on the drug particles generated by the rotation of the separation belt will peel off the drug particles that are gathered together, thereby dispersing the agglomerated particles. In addition, the airflow ejected from the nozzle can also cool the drug particles, facilitating subsequent packaging processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0025] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0026] Figure 2 It is a schematic diagram of the drying bin structure of the present invention;

[0027] Figure 3 yes Figure 2 A partial enlarged view of the A direction;

[0028] Figure 4 It is a schematic diagram of the feeding mechanism structure;

[0029] Figure 5 is a schematic diagram of the structure of the regulating component;

[0030] Figure 6 yes Figure 5 A local B-direction enlarged view;

[0031] Figure 7 It is a schematic diagram of the decentralized organization structure;

[0032] Figure 8 It is a schematic diagram of the dispersion process;

[0033] In the figure: 1-frame, 2-hot air blower, 3-feeding mechanism, 31-shell, 32-star wheel, 33-drive motor, 4-drying bin, 41-bin, 411-air inlet, 412-feeding port, 413-exhaust port, 414-discharge port, 415-movable slot, 42-porous partition, 5-vibration motor, 6-temperature regulating mechanism, 61-detection component, 611-base, 612-pressure strain gauge, 613-movable plate, 62-adjusting component, 621-rotating blade, 622-rotating shaft, 623-transmission gear, 624-rack, 625-electric push rod, 7-dispersion mechanism, 71-rotating motor, 72-drive roller, 73-redirecting roller, 74-separation belt, 741-protrusion, 75-jet head. DETAILED DESCRIPTION

[0034] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0035] The present invention provides a technical solution:

[0036] like Figure 1 As shown, the drying equipment includes a frame 1, a hot air blower 2, a feeding mechanism 3, and a drying bin 4. The hot air blower 2 is firmly connected to the frame 1, and the drying bin 4 is connected to an air outlet of the hot air blower 2. The hot air blower 2 is used to provide heat to the drying bin 4. The feeding mechanism 3 is connected to the drying bin 4, and the feeding mechanism 3 is used for quantitative feeding. A vibration motor 5 is provided on the drying bin 4.

[0037] The frame 1 provides stable support for each mechanism to ensure the stable operation of the equipment. The pharmaceutical particles that need to be dried are quantitatively added into the drying bin 4 for drying through the feeding mechanism 3. The hot air blower 2 is started to provide a stable hot air flow for the drying bin 4. The vibration motors 5 on both sides of the drying bin 4 are started. The drying bin 4 generates directional and uniform vibration under the exciting force of the vibration motor 5, thereby transporting the pharmaceutical particles in the drying bin 4 to make them evenly dried.

[0038] like Figure 2 As shown, the drying bin 4 includes a bin body 41 and a porous partition 42. The bin body 41 is firmly connected to the frame 1, and the porous partition 42 is firmly connected to the bin body 41. The bin body 41 is provided with an air inlet 411, a feed port 412, an exhaust port 413, and a discharge port 414. The air inlet 411 is connected to the air outlet of the hot air blower 2, the feed port 412 is connected to the feeding mechanism 3, and the exhaust port 413 is used to discharge the hot and humid gas generated by drying.

[0039] The bin body 41 and the porous partition 42 are both made of stainless steel to ensure the hygiene and safety of the drying process. The frame 1 provides stable support for the bin body 41. The hot air flow of the hot air blower 2 flows into the bin body 41 through the air inlet 411. After entering the bin body 41, the drug particles will fall onto the porous partition 42 located at the bottom of the bin body 41. The hot air flow blows upward from the bottom of the porous partition 42, so that the drug particles move on the porous partition 42 and are suspended under the blowing of the hot air flow, which promotes the mixing of the drug particles and the hot air flow, so that the drug particles are fully in contact with the hot air flow, and heat and moisture are transferred between the two, thereby drying the drug particles and gradually moving toward the discharge port 414 under the action of the vibration motor 5. The hot and humid gas generated during the drying process is discharged through the exhaust port 413.

[0040] like Figure 2 , Figure 4 As shown, the feeding mechanism 3 includes a shell 31, a star wheel 32, and a driving motor 33. The shell 31 is connected to the drying bin 4, the star wheel 32 is rotationally connected to the shell 31, the driving motor 33 is fastened to the shell 31, and the output shaft of the driving motor 33 is transmission-connected to the star wheel 32.

[0041] The shell 31 is fixed on the drying bin 4 to provide a stable working platform for the driving motor 33. The output shaft of the driving motor 33 transmits power to the star wheel 32 through a belt, thereby driving the star wheel 32 to rotate in the shell 31, thereby dividing the drug particles entering the feeding mechanism 3 into parts of the same volume, and driven by the rotating star wheel 32, gradually adding them into the drying bin 4 for drying, so that the feed flow rate remains stable, ensuring the drying effect.

[0042] like Figure 2 As shown, a temperature regulating mechanism 6 and a dispersing mechanism 7 are further provided in the warehouse body 41 . The temperature regulating mechanism 6 is located in the air inlet 411 , and the dispersing mechanism 7 is located in the discharge port 414 .

[0043] The dryness and wetness of the drug particles obtained by the wet granulator will have a certain deviation, so the moisture content of the drug particles added to the bin 41 for drying will be different. If the same temperature is used for drying, the material with a low moisture content will be too dry after drying and easily break, affecting the quality of the drug. Therefore, the temperature regulating mechanism 6 is required to automatically adjust the drying temperature according to the moisture content of the added drug particles to ensure the drying quality. The temperature regulating mechanism 6 adjusts the drying temperature by adjusting the air intake of the air inlet 411. The moist drug particles will move along the porous partition 42 during drying and are prone to agglomeration. The agglomerated drug powder particles are dispersed by the dispersion mechanism 7 to ensure the quality of the finished product.

[0044] like Figure 2 , Figure 3As shown, the temperature regulating mechanism 6 includes a detection component 61 and an adjustment component 62. The detection component 61 is electrically connected to the adjustment component 62. The detection component 61 is fastened to the bin body 41. The detection component 61 is located directly below the feed port 412. The adjustment component 62 is fastened to the bin body 41. The adjustment component 62 is located in the air inlet 411.

[0045] The detection component 61 is used to detect the moisture content of the drug particles, and then control the action of the adjustment component 62 according to the measured data to adjust the drying temperature. The feeding mechanism 3 divides the drug particles into components of the same volume and adds them into the bin body 41 in sequence for drying. For the drug powder particles of the same volume, the higher the moisture content and the heavier the weight, the greater the impact force on the detection component 61 when falling into the bin body 41. The detection component 61 is arranged directly below the feed port 412 to facilitate the detection of the impact force when the drug particles fall. The greater the impact force, the higher the moisture content. The drying temperature is then adjusted by adjusting the air intake volume through the adjustment component 62 located in the air inlet 411.

[0046] like Figure 2 , Figure 3 As shown, the detection component 61 includes a base 611, a pressure strain gauge 612, and a movable plate 613. The base 611 is fastened to the chamber body 41, the pressure strain gauge 612 is fastened to the base 611, the pressure strain gauge 612 is externally connected to a detection power supply, the pressure strain gauge 612 and the detection power supply constitute a detection circuit, the detection circuit is electrically connected to the adjustment component 62, the movable plate 613 is slidably connected to the base 611, and the movable plate 613 abuts against the pressure strain gauge 612.

[0047] The drug particles will collide with the movable plate 613 during the falling process, thereby pushing the movable plate 613 to slide downward on the base 611, causing the pressure strain gauge 612 to be compressed. The resistance of the compressed pressure strain gauge 612 will change and is proportional to the pressure received. The detection power supply and the pressure strain gauge 612 are energized to form a detection circuit. The detection circuit can detect the change in the resistance of the pressure strain gauge to determine the impact force of the drug particles on the movable plate, and then determine the moisture content of the drug particles. The higher the moisture content, the greater the impact force, and the action of the adjustment component 62 is controlled according to this electrical signal.

[0048] like Figure 2 , Figure 5 , Figure 6As shown, the adjustment component 62 includes a rotating blade 621, a rotating shaft 622, a transmission gear 623, a rack 624, and an electric push rod 625. The rotating shaft 622 is rotatably connected to the warehouse body 41, the rotating blade 621 is firmly connected to the rotating shaft 622, the transmission gear 623 is firmly connected to the rotating shaft 622, a movable groove 415 is provided on the warehouse body 41, the rack 624 is slidably connected to the movable groove 415, the output end of the electric push rod 625 is transmission-connected to the rack 624, the electric push rod 625 is firmly connected to the warehouse body 41, and the transmission gear 623 is meshed with the rack 624.

[0049] The adjusting component 62 adjusts the air intake by adjusting the angle of the rotating blades 621. When the rotating blades 621 are parallel to each other, the air intake is maximum and the drying temperature is highest. According to the moisture content of the drug particles measured by the detecting component 61, the angle of the rotating blades 621 is adjusted by the electric push rod 625. The electric push rod 625 moves to push the rack 624 to slide along the movable groove 415, thereby driving the transmission gear 623 meshing with the rack 624 to rotate, and then driving the rotating shaft 622 to rotate along the bin body 41, so that the angle of the rotating blades 621 changes. The higher the moisture content of the drug particles, the more the angles between the rotating blades 621 tend to be parallel, thereby realizing the function of automatically adjusting the drying temperature according to the moisture content of the drug particles, thereby improving the drying quality.

[0050] like Figure 2 , Figure 7 , Figure 8 As shown, the vertical cross-section of the discharge port 414 is an inverted trapezoid, and the dispersion mechanism 7 includes a rotating motor 71, a driving roller 72, a redirecting roller 73, a separating belt 74, and an air jet 75. The rotating motor 71 is firmly connected to the bin body 41, and the output end of the rotating motor 71 is transmission-connected to the driving roller 72, the driving roller 72 is rotationally connected to the bin body 41, the separating belt 74 is transmission-connected to the driving roller 72, the separating belt 74 is rotationally connected to the redirecting roller 73, and the air jet 75 is firmly connected to the bin body 41, and the air outlet end of the air jet 75 faces the discharge port 414, and the movement direction of the separating belt 74 is opposite to the movement direction of the material.

[0051] By setting the vertical cross-section of the discharge port 414 to an inverted trapezoid, the discharge path of the drug particles is constrained, and the contracted discharge port 414 can block the drug particles that are agglomerated together, so that the dispersion mechanism 7 can disperse the agglomerates. The rotating motor 71 is the main power source of the dispersion mechanism 7. The rotating motor 71 is started to drive the driving roller 72 to rotate, thereby driving the separation belt 74 to rotate. The redirecting roller 73 is used to constrain the moving trajectory of the separation belt 74. The airflow ejected by the nozzle 75 gives the drug particles a driving force, so that the drug particles collide with the separation belt 74. Because the movement direction of the separation belt 74 is opposite to the movement direction of the material, when the agglomerated drug particles collide with the separation belt 74, the impact force generated by the collision and the friction force on the drug particles generated by the rotation of the separation belt 74 will peel off the agglomerated drug particles, thereby dispersing the agglomerated particles, and the airflow ejected by the nozzle 75 can also play a cooling role on the drug particles, which is convenient for subsequent packaging processing.

[0052] like Figure 2 , Figure 7 , Figure 8 As shown, a protrusion 741 is provided on the separation belt 74.

[0053] In order to increase the friction between the drug particles and the separation belt 74 and improve the peeling and dispersion effect, protrusions 741 are provided on the separation belt 74 .

[0054] The working principle of the present invention is as follows: first, the drug particles are divided into components of the same volume through the feeding mechanism 3 and added into the bin body 41 in sequence for drying. For drug powder particles of the same volume, the higher the moisture content and the heavier the weight, the greater the impact force on the detection component 61 when falling into the bin body 41. The detection component 61 is arranged directly below the feed port 412 to facilitate the detection of the impact force of the drug particles when they fall. The greater the impact force, the higher the moisture content. The air intake volume is then adjusted by the adjustment component 62 located in the air inlet 411 to adjust the drying temperature. The adjustment component 62 adjusts the air intake volume by adjusting the angle of the rotating blades 621. When the rotating blades 621 are parallel to each other, the air intake volume is the largest and the drying temperature is the highest. The discharge path of the drug particles is constrained by setting the vertical section of the discharge port 414 to an inverted trapezoid, and The contracted discharge port 414 can block the drug particles that are clustered together so that the dispersing mechanism 7 can disperse the clusters. The rotating motor 71 is the main power source of the dispersing mechanism 7. The rotating motor 71 is started to drive the driving roller 72 to rotate, thereby driving the separation belt 74 to rotate. The redirecting roller 73 is used to constrain the moving trajectory of the separation belt 74. The airflow ejected by the nozzle 75 gives a driving force to the drug particles, causing the drug particles to collide with the separation belt 74. Because the movement direction of the separation belt 74 is opposite to the movement direction of the material, when the clustered drug particles collide with the separation belt 74, the impact force generated by the collision and the friction force on the drug particles generated by the rotation of the separation belt 74 will peel off the clustered drug particles, thereby dispersing the clustered particles. Finally, the material is discharged through the discharge port 414 for subsequent packaging processing.

[0055] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0056] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A drying device for producing fenofibrate capsules with a temperature control function, characterized in that: The drying device comprises a frame (1), a hot air blower (2), a feeding mechanism (3), and a drying chamber (4); the hot air blower (2) is firmly connected to the frame (1); the drying chamber (4) is communicated with an air outlet of the hot air blower (2); the hot air blower (2) is used to provide heat to the drying chamber (4); the feeding mechanism (3) is communicated with the drying chamber (4); the feeding mechanism (3) is used to feed quantitatively; and a vibration motor (5) is provided on the drying chamber (4); The drying bin (4) comprises a bin body (41) and a porous partition (42); the bin body (41) is firmly connected to the frame (1); the porous partition (42) is firmly connected to the bin body (41); an air inlet (411), a material feed port (412), an exhaust port (413), and a material discharge port (414) are provided on the bin body (41); the air inlet (411) is communicated with an air outlet of a hot air blower (2); the material feed port (412) is communicated with a material feed mechanism (3); and the exhaust port (413) is used to discharge hot and humid gases generated by drying; The feeding mechanism (3) comprises a housing (31), a star wheel (32), and a driving motor (33); the housing (31) is in communication with the drying bin (4); the star wheel (32) is rotationally connected to the housing (31); the driving motor (33) is firmly connected to the housing (31); and the output shaft of the driving motor (33) is drivingly connected to the star wheel (32); A temperature regulating mechanism (6) and a dispersing mechanism (7) are also provided in the warehouse body (41); the temperature regulating mechanism (6) is located in the air inlet (411), and the dispersing mechanism (7) is located in the discharge port (414); The temperature adjustment mechanism (6) comprises a detection component (61) and an adjustment component (62), the detection component (61) and the adjustment component (62) are electrically connected, the detection component (61) is tightly connected to the bin body (41), the detection component (61) is located directly below the feed port (412), the adjustment component (62) is tightly connected to the bin body (41), and the adjustment component (62) is located in the air inlet (411); The detection component (61) comprises a base (611), a pressure strain gauge (612), and a movable plate (613); the base (611) is tightly connected to the chamber body (41); the pressure strain gauge (612) is tightly connected to the base (611); the pressure strain gauge (612) is externally connected to a detection power supply; the pressure strain gauge (612) and the detection power supply form a detection circuit; the detection circuit is electrically connected to the adjustment component (62); the movable plate (613) is slidably connected to the base (611); and the movable plate (613) abuts against the pressure strain gauge (612); The adjustment component (62) comprises a rotating blade (621), a rotating shaft (622), a transmission gear (623), a rack (624), and an electric push rod (625); the rotating shaft (622) is rotationally connected to the warehouse body (41); the rotating blade (621) is firmly connected to the rotating shaft (622); the transmission gear (623) is firmly connected to the rotating shaft (622); a movable groove (415) is provided on the warehouse body (41); the rack (624) is slidably connected to the movable groove (415); an output end of the electric push rod (625) is transmission-connected to the rack (624); the electric push rod (625) is firmly connected to the warehouse body (41); and the transmission gear (623) is meshed with the rack (624); The vertical cross-section of the discharge port (414) is in an inverted trapezoidal shape. The dispersion mechanism (7) comprises a rotating motor (71), a driving roller (72), a redirecting roller (73), a separation belt (74), and an air jet head (75). The rotating motor (71) is firmly connected to the bin body (41). The output end of the rotating motor (71) is transmission-connected to the driving roller (72). The driving roller (72) is rotationally connected to the bin body (41). The separation belt (74) is transmission-connected to the driving roller (72). The separation belt (74) is rotationally connected to the redirecting roller (73). The air jet head (75) is firmly connected to the bin body (41). The air outlet end of the air jet head (75) faces the discharge port (414). The movement direction of the separation belt (74) is opposite to the movement direction of the material.

2. The drying equipment for producing fenofibrate capsules with temperature control function according to claim 1, characterized in that: The separation belt (74) is provided with a protrusion (741).

Citation Information

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