Prosthetic system to improve heart valve coaptation

Abstract

The present application relates to the field of medical devices, and in particular to a repair system for improving the engagement of heart valves, comprising an outer sheath, an artificial valve leaflet, an anchoring needle, and an adjusting device, wherein the adjusting device comprises a first tube, a first guide wire, a second tube, a second guide wire, an abutment member, a threaded needle, a fitting member, and an operating rod, wherein the first tube is detachably connected to the artificial valve leaflet via the first guide wire, the fitting member is arranged between the first tube and the second tube, and when the operating rod is rotated to allow the threaded needle to pass through the artificial valve leaflet and penetrate into the heart tissue, the fitting member is located in the middle region of the artificial valve leaflet close to the native valve ring, so that the middle region is in close contact with the atrial tissue or the native valve leaflet; the present invention can effectively avoid the presence of a gap between the closing aid and the native valve leaflet, so that blood flows into the gap and causes adverse conditions such as thrombus accumulation and calcification, and has great clinical significance.

Description

Technical Field

[0001] The present application relates to the field of medical devices, and in particular to a repair system for improving heart valve coaptation. Background Art

[0002] The mitral valve is located at the left atrioventricular orifice and is composed of five parts: the valve ring, valve leaflets, chordae tendineae, papillary muscles, and commissural connections. Its accurate anatomical name is the mitral apparatus (mitral apparatus) or mitral complex (mitral complex).

[0003] The tricuspid valve is located at the right atrioventricular orifice and has three nearly triangular sail-shaped valves. The base of the valve is attached to the fibrous ring of the atrioventricular orifice. Functionally, the fibrous ring, valve, chordae tendineae and papillary muscles can be seen, forming the tricuspid valve complex (tricuspidvalvarcomplex).

[0004] Mitral regurgitation can be divided into the following two types: 1. Rheumatic mitral regurgitation, mainly caused by mitral valve insufficiency, can cause blood to flow in reverse, thereby mixing different bloods, causing the heart to pump blood and oxygen delivery function to decline. 2. Non-rheumatic mitral regurgitation, usually refers to mitral regurgitation of varying degrees caused by abnormalities of the mitral valve itself and its surrounding anatomical structures in addition to rheumatic valvular disease. There are many causes of non-rheumatic mitral regurgitation, the more common ones are: mitral valve prolapse, papillary muscle insufficiency or chordae tendineae rupture, left atrial myxoma, valve ring calcification, congenital valve malformation, infective endocarditis, etc. Mitral regurgitation can also be divided into three types: functional, degenerative or mixed. The most common are degenerative and functional mitral regurgitation. Functional mitral regurgitation is generally secondary to impaired left ventricular wall motion, left ventricular dilatation, and papillary muscle dysfunction, and is generally seen in patients with heart failure. This group of patients also includes ischemic mitral regurgitation secondary to coronary artery disease and mitral regurgitation associated with non-ischemic cardiomyopathy. Degenerative mitral regurgitation disease is generally considered to be a pathological change in the valve structure or pathological changes in the subvalvular structure, including abnormal extension or rupture of the chordae tendineae.

[0005] When the mitral valve is diseased, we usually replace the diseased posterior leaflet so that the implanted patch can be aligned with the anterior leaflet. For example, patent CN202210058417.8 discloses a repair device with a bionic leaflet morphology, including a first skeleton and a closing aid. After the repair device is implanted, the first skeleton is fixed to the native valve annulus or atrial tissue, and the closing aid can move with the movement of the native valve leaflet. The repair device also includes a shape retaining member, one end of which is connected to the first skeleton, and the shape retaining member is attached to the closing aid. When the native valve is in a closed state, the part of the closing aid close to the native valve annulus is supported by the shape retaining member. Although the shape retaining member in the patent solution can provide effective shape support for the upper part of the closing aid, its first skeleton is difficult to be anchored tightly against the native valve ring due to the invisible reason during the surgical operation. The fixed position of the first skeleton is usually above the native valve ring, which will cause some space to exist between the root area of ​​the closing aid and the root area of ​​the native valve ring. When the valve is closed, blood will flow into this space and further flow out to both sides of the closing aid, causing blood reflux. In addition, long-term blood accumulation will also cause calcification, thrombosis and other problems in this area.

[0006] In summary, the repair device in the prior art has at least the following technical pain points: after the shape retaining member is set, although the arched shape of the closing aid can be maintained, due to the uncertainty of the needle insertion position, a gap space will be generated between the root area and the native valve ring. When the valve opens and closes, part of the blood will accumulate in this area, forming adverse conditions such as thrombosis and calcification. In addition, the blood accumulated in the root area will flow out from the two sides of the root of the closing aid, causing paravalvular leakage and affecting the repair effect. Summary of the invention

[0007] This application is proposed in view of the above and other more concepts.

[0008] One of the purposes of the present application is to overcome the deficiencies of the prior art and to provide a repair system for improving heart valve coaptation, for example, to address the problems of blood congestion and bilateral paravalvular leakage between the root of the closing aid and the root of the native valve leaflet in the prior art.

[0009] The technical solution adopted to solve the technical problem of the present invention is to provide a repair system for improving the engagement of a heart valve, comprising an outer sheath, an artificial valve leaflet arranged in the outer sheath, an anchoring needle for anchoring the artificial valve leaflet, and an adjustment device detachably connected to the artificial valve leaflet, wherein the adjustment device comprises a first tube, a first guide wire, a second tube arranged in the first tube, a second guide wire, a support member arranged at the head end of the second tube, a threaded needle arranged in the second tube, a fitting component connected to the threaded needle, and a control rod detachably connected to the tail of the threaded needle, wherein the first tube is detachably connected to the artificial valve leaflet through the first guide wire, the fitting component is arranged between the first tube and the second tube, and when the control rod is rotated so that the threaded needle passes through the artificial valve leaflet and penetrates into the heart tissue, the fitting component is located in the middle area of ​​the artificial valve leaflet close to the native valve ring, so that the middle area is in close contact with the atrial tissue or the native valve leaflet.

[0010] As a further improvement of the present invention, the abutment member includes a first developing ring, a second developing ring, and an elastic member arranged between the first developing ring and the second developing ring. The second guide wire is tightened, the first developing ring abuts against the artificial valve leaflet, and pushes the second tube to compress the elastic member. The first developing ring and the second developing ring are fitted together, and the control rod is rotated so that the threaded needle passes through the artificial valve leaflet and penetrates into the heart tissue.

[0011] As a further improvement of the present invention, a buffer structure is provided on the first developing ring.

[0012] As a further improvement of the present invention, the artificial valve leaflet includes a mate plate and a fixing bracket arranged at the distal end of the mate plate, the fixing bracket is provided with an anchoring area, and the first tube and the second tube are detachably connected to the anchoring area through the first guide wire and the second guide wire respectively.

[0013] As a further improvement of the present invention, the apposition piece is made of biological material (such as bovine pericardium or porcine pericardium), and of course it can also be made of polymer material. The apposition piece is arched in shape to facilitate better apposition with the native valve leaflet to prevent reflux.

[0014] As a further improvement of the present invention, the fitting component includes a lower pressing plate and an anti-twist member, the lower pressing plate includes a connecting portion and a lower pressing portion, wherein the connecting portion is sleeved on the root of the threaded needle, and the connecting portion has a preset shape.

[0015] As a further improvement of the present invention, after the first developing ring is in close contact with the anchoring area, the first tube is withdrawn so that the connecting portion returns to a preset shape, and the lower pressing plate is located in the middle area of ​​the matching plate close to the autologous valve ring.

[0016] As a further improvement of the present invention, the longer the stroke of the threaded needle penetrating into the heart tissue, the shorter the distance between the downward pressing portion and the atrial wall or the native valve leaflet; that is, the deeper the threaded needle penetrates into the heart tissue, the greater the degree of downward pressing of the fitting component. This allows the degree to which the fitting component presses down on the fitting piece to be adjusted by the threaded needle to adapt to the differences in physiological and anatomical structures between different patients, while also ensuring that there is no gap between the fitting piece and the root of the native valve leaflet.

[0017] As a further improvement of the present invention, the connecting part includes a plurality of memory metal wires. Since they are not visible during the operation, the position of the anchoring needle may be on the atrial wall, resulting in a certain height difference between the root of the apposition piece and the native valve ring, creating a layer gap space, and blood will accumulate in this space. Therefore, the fitting component is a hard part with a certain rigidity, so that the fitting component can press the apposition piece down close to the middle area of ​​the native valve ring (the middle area is the main area for blood accumulation), so that the apposition piece can be close to the heart tissue and prevent blood from entering between the apposition piece and the native valve leaflet.

[0018] As a further improvement of the present invention, the pressing part includes a frame and a fabric layer wrapped on the frame, the frame is composed of a plurality of metal wires and is arranged in a grid structure, and the longitudinal arrangement density of the metal wires is greater than the transverse arrangement density.

[0019] As a further improvement of the present invention, one end of the anti-twist-away member is fixed to the anchoring area, and the other end of the anti-twist-away member is fixed to the lower pressure plate, wherein the anti-twist-away member includes a first anti-twist-away member and a second anti-twist-away member respectively arranged on the left and right sides of the lower pressure plate, so that when the threaded needle rotates, the lower pressure plate remains stationary in the circumferential direction.

[0020] As a further improvement of the present invention, the first anti-twist member and the second anti-twist member may be in a strip-like form, so that the connection area with the anchoring area can be increased, thereby more effectively preventing the lower pressing plate from rotating.

[0021] As a further improvement of the present invention, an arched rod is provided on the mating piece, and the area between the proximal end of the fixed bracket and the rod is called an anti-side leakage area, and both sides of the anti-side leakage area are respectively provided with a backward curled socket-shaped portion.

[0022] Compared with the prior art, the advantages of the technical solution of the present application include at least the following:

[0023] In the prior art, when the implant is anchored, the anchoring position of the fixing bracket is generally higher than the native valve ring because the operation is not visible during the operation. This results in a gap between the root of the artificial valve leaflet and the root area of ​​the native valve leaflet, causing blood to flow into the gap when the valve is closed, resulting in blood shunting from both sides of the closing aid, and valve regurgitation and other adverse conditions. According to an idea of ​​the present application, a fitting component is provided at the distal end of the clasping piece, and the fitting component is located in the middle area of ​​the clasping piece close to the native valve ring, thereby squeezing out the space between the root of the clasping piece and the root of the native valve ring, so that the root of the clasping piece can be close to the native valve ring or the atrial wall, effectively preventing blood from accumulating between the clasping piece and the native valve leaflet, and avoiding regurgitation and thrombosis.

[0024] Due to the lack of visibility during the operation, it is difficult for the control lever to confirm whether the anchoring area is in close contact with the heart tissue before rotating the threaded needle. According to an idea of ​​the present application, a support member is provided at the head end of the second tube, and the support member includes a first developing ring, a second developing ring and an elastic member. By observing the relative positions of the first developing ring and the second developing ring through imaging, it can be determined whether the anchoring area is in close contact with the heart tissue, thereby preventing the threaded needle from idling.

[0025] According to one concept of the present application, a threaded needle is used to fix the fitting component, and the longer the threaded needle enters into the heart tissue, the greater the degree to which the fitting component is pressed down. On the one hand, the degree to which the fitting component presses down the fitting piece can be adjusted by the threaded needle to adapt to the differences in physiological and anatomical structures between different patients, while also ensuring that there is no gap between the fitting piece and the root of the autologous valve leaflet.

[0026] According to one concept of the present application, the degree of downward pressure of the fitting component can be adjusted by rotating the threaded needle, and an anti-twist part is also provided to effectively prevent the downward pressure plate from rotating circumferentially during the rotation of the threaded needle, resulting in deviation in the downward pressure position.

[0027] The embodiments of the present application can achieve other advantageous technical effects that are not listed one by one. These other technical effects may be partially described below and are predictable and understandable to those skilled in the art after reading the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] The above-mentioned features and advantages and other features and advantages of these embodiments and the manner in which they are achieved will become more apparent, and the embodiments of the present application can be better understood by referring to the following description together with the accompanying drawings, in which:

[0029] Figure 1 It is a schematic diagram of the pre-assembly of the fitting parts in the repair system of the present invention.

[0030] Figure 2 for Figure 1 Enlarged view of part A in the middle.

[0031] Figure 3 It is a schematic diagram of the overall structure of the artificial valve leaflet of the present invention.

[0032] Figure 4-Figure 7 It is a schematic diagram of the operation process of the repair system of the present invention.

[0033] The features indicated by the numbers in the accompanying drawings are as follows:

[0034] 1-outer sheath, 2-artificial valve leaflet, 21-matching piece, 22-fixing bracket, 23-anchoring area, 3-anchoring needle, 4-adjusting device, 41-first tube, 42-first guide wire, 43-second tube, 44-second guide wire, 45-abutment member, 451-first developing ring, 452-second developing ring, 453-elastic member, 454-buffering structure, 46-threaded needle, 47-fitting member, 471-lower pressing piece, 4711-connecting part, 4712-lower pressing part, 47121-skeleton, 47122-fabric layer, 472-anti-twist member, 4721-first anti-twist member, 4722-second anti-twist member, 5-rod, 6-anti-side leakage area, 7-nest-shaped part. DETAILED DESCRIPTION

[0035] In the following description of the drawings and specific embodiments, the details of one or more embodiments of the present application will be described. From these descriptions, drawings and claims, other features, purposes and advantages of the present application can be clearly seen.

[0036] It should be understood that the illustrated and described embodiments are not limited in application to the details of the construction and arrangement of the components set forth in the following description or illustrated in the accompanying drawings. The illustrated embodiments may be other embodiments and may be implemented or executed in various ways. Each example is provided by explaining the disclosed embodiments rather than limiting them. In fact, it will be apparent to those skilled in the art that various modifications and variations may be made to the embodiments of the present application without departing from the scope or essence disclosed in the present application. For example, a feature illustrated or described as part of an embodiment may be used together with another embodiment to still produce another embodiment. Therefore, the present application discloses and covers such modifications and variations within the scope of the appended claims and their equivalent elements.

[0037] Likewise, it is understood that the phrases and terms used herein are for descriptive purposes and should not be considered restrictive. The use of "include," "comprise," or "have" and variations thereof herein is intended to be open-ended to include the items listed thereafter and their equivalents and additional items.

[0038] The present application will be described in more detail below with reference to different embodiments and examples of several aspects of the present application.

[0039] One of the purposes of the embodiments described below is to address the above-mentioned deficiencies, as well as other problems.

[0040] Embodiment 1

[0041] like Figures 1 to 3 As shown, a repair system for improving heart valve coaptation according to an embodiment of the present application is illustrated, comprising an outer sheath tube 1, an artificial valve leaflet 2 disposed in the outer sheath tube 1, an anchoring needle 3 for anchoring the artificial valve leaflet 2, and an adjusting device 4 detachably connected to the artificial valve leaflet 2, wherein the adjusting device 4 comprises a first tube 41, a first guide wire 42, a second tube 43 disposed in the first tube 41, a second guide wire 44, an abutment member 45 disposed at the head end of the second tube 43, a threaded needle 46 disposed in the second tube 43, and a threaded needle 46 disposed in the second tube 43. A fitting component 47 connected thereto, and a control rod detachably connected to the tail of the threaded needle 46, wherein the first tube 41 is detachably connected to the artificial valve leaflet 2 through the first guide wire 42, the fitting component 47 is arranged between the first tube 41 and the second tube 43, and when the control rod is rotated so that the threaded needle 46 passes through the artificial valve leaflet 2 and penetrates into the heart tissue, the fitting component 47 is located in the middle area of ​​the artificial valve leaflet 2 close to the autologous valve ring, so that the middle area is in close contact with the atrial tissue or the autologous valve leaflet.

[0042] In this embodiment, the abutting member 45 includes a first developing ring 451, a second developing ring 452, and an elastic member 453 disposed between the first developing ring 451 and the second developing ring 452. The second guide wire 44 is tightened, the first developing ring 451 abuts against the artificial valve leaflet 2, and pushes the second tube 43 so that the elastic member 453 is compressed, and the first developing ring 451 and the second developing ring 452 are fitted together. Figure 5 As shown, the control rod is rotated so that the threaded needle 46 passes through the artificial valve leaflet 2 and penetrates into the heart tissue. Figure 6 shown.

[0043] In this embodiment, a buffer structure 454 is disposed on the second developing ring 452 . The buffer structure 454 is a polymer membrane or a biological pericardial material, so as to prevent the second developing ring 452 from causing damage to tissues.

[0044] In this embodiment, the artificial valve leaflet 2 includes a mate plate 21 and a fixing bracket 22 arranged at the distal end of the mate plate 21, and an anchoring area 23 is provided on the fixing bracket 22. The first tube 41 and the second tube 43 are detachably connected to the anchoring area 23 through the first guide wire 42 and the second guide wire 44 respectively.

[0045] In this embodiment, the apposition piece 21 is made of biological material (such as bovine pericardium or porcine pericardium), and of course it can also be made of polymer material. The apposition piece 21 is arched in shape to facilitate better apposition with the native valve leaflet to prevent reflux.

[0046] In this embodiment, the fitting component 47 includes a lower pressing piece 471 and an anti-twist piece 472, and the lower pressing piece 471 includes a connecting portion 4711 and a lower pressing portion 4712, wherein the connecting portion 4711 is sleeved at the root of the threaded needle 46, and the connecting portion 4711 has a preset shape, such as Figure 3 shown.

[0047] In this embodiment, after the first developing ring 451 is in close contact with the anchoring area 23, the first tube 41 is withdrawn so that the connecting portion 4711 returns to a preset shape, and the lower pressing plate 471 is located in the middle area of ​​the matching plate 21 close to the autologous valve ring.

[0048] In this embodiment, the longer the stroke of the threaded needle 46 penetrating into the heart tissue, the shorter the distance between the downward pressing portion 4712 and the atrial wall or the native valve leaflet; that is, the deeper the threaded needle 46 penetrates into the heart tissue, the greater the degree of downward pressing of the fitting component 47. This allows the degree to which the fitting component 47 presses down on the closure plate 21 to be adjusted by the threaded needle 46 to adapt to the differences in physiological and anatomical structures between different patients, while also ensuring that there is no gap between the closure plate 21 and the root of the native valve leaflet.

[0049] In this embodiment, the connecting portion 4711 includes a plurality of memory metal wires. Since they are not visible during the operation, the anchoring needle 3 may be inserted at the atrial wall, resulting in a certain height difference between the root of the apposition piece 21 and the native valve ring, creating a laminar space in which blood flow will accumulate. Figure 4 As shown, the fitting member 47 is a hard member with a certain rigidity, so that the fitting member 47 can press the fitting piece 21 down to the middle area close to the native valve ring (the middle area is the main area where blood accumulates), so that the fitting piece 21 can be close to the heart tissue to prevent blood from entering between the fitting piece 21 and the native valve leaflet. Figure 7 shown.

[0050] In this embodiment, during pre-assembly, one end of the connecting portion 4711 is sleeved on the threaded needle 46, and the other end thereof passes through the elastic member 453 (i.e., the spring) and is bent, so that the pressing portion 4712 is restricted between the first tube member 41 and the second tube member 43. Figure 1 As shown, when the first tube 41 is withdrawn, the downward pressure portion 4712 is released, and the connecting portion 4711 restores the preset shape so that the downward pressure portion 4712 is located in the middle area of ​​the mate plate 21 close to the native valve ring, so that the mate plate 21 can be close to the heart tissue to prevent blood from entering between the mate plate 21 and the native valve leaflet.

[0051] In this embodiment, the pressing portion 4712 includes a frame 47121 and a fabric layer 47122 wrapped on the frame 47121. The frame 47121 is composed of a plurality of metal wires and is arranged in a grid structure. In addition, the longitudinal arrangement density of the metal wires is greater than the transverse arrangement density. Figure 3 shown.

[0052] In this embodiment, one end of the anti-twist component 472 is fixed to the anchoring area 23, and the other end of the anti-twist component 472 is fixed to the lower pressure plate 471, wherein the anti-twist component 472 includes a first anti-twist component 4721 and a second anti-twist component 4722 respectively arranged on the left and right sides of the lower pressure plate 471, so that when the threaded needle 46 rotates, the lower pressure plate 471 remains stationary in the circumferential direction.

[0053] In this embodiment, an arched rod 5 is provided on the mating piece 21, and the area between the proximal end of the fixing bracket 22 and the rod 5 is called a side leakage prevention area 6, and both sides of the side leakage prevention area 6 are respectively provided with a backward curled recessed portion 7.

[0054] An exemplary operation process of repairing a mitral valve of a repair system for improving heart valve coaptation in the first embodiment is as follows:

[0055] 1. The delivery system enters the patient's heart through a transvascular route, passes through the patient's atrial septum to the left atrium, and is fixed to the native valve annulus through an anchoring needle 3;

[0056] 2. Pull the first guide wire 42 so that the first tube 41 moves along the path of the first guide wire 42 and abuts against the anchoring area 23, as shown in FIG. Figure 4 As shown, the second guide wire 44 is then pulled to push the second tube 43 to move along the path of the second guide wire 44 and abut against the anchoring area 23;

[0057] 3. Retract the first tube 41 to release the lower pressing sheet 471 from the first tube 41, push the second tube 43 and observe the image until the first developing ring 451 and the second developing ring 452 abut against each other, confirming that the anchoring area 23 is in close contact with the heart tissue. Figure 5 As shown;

[0058] 4. Turn the control rod so that the threaded needle 46 passes through the anchoring area 23 and pierces the heart tissue. Observe the blood flow through the image. After confirming that there is no backflow, separate the control rod and the threaded needle 46. Figure 6 As shown;

[0059] 5. withdrawing the delivery device of the heart valve implant device and completing the operation, such as Figure 7 shown.

[0060] The foregoing description of the above-described embodiments of the present application is presented for illustrative purposes. The foregoing description is not intended to be exhaustive, nor is it intended to limit the present application to the precise configurations, constructions, and / or steps disclosed, and it is apparent that many modifications and variations may be made in light of the teachings above. The scope of the present invention and all equivalents are intended to be defined by the appended claims.

Claims

1. A repair system for improving heart valve coaptation, comprising an outer sheath, an artificial valve leaflet disposed in the outer sheath, an anchoring needle for anchoring the artificial valve leaflet, and an adjustment device detachably connected to the artificial valve leaflet, characterized in that: The adjusting device comprises a first tube, a first guide wire, a second tube arranged in the first tube, a second guide wire, a supporting member arranged at the head end of the second tube, a threaded needle arranged in the second tube, a fitting component connected to the threaded needle, and a control rod detachably connected to the tail of the threaded needle, the fitting component comprises a lower pressure plate and an anti-twist component, the lower pressure plate comprises a connecting portion and a lower pressure portion, the connecting portion comprises a plurality of memory metal wires, and the lower pressure portion is a hard component, wherein the first tube is detachably connected to the artificial valve leaflet through the first guide wire, the fitting component is arranged between the first tube and the second tube, and when the control rod is rotated so that the threaded needle passes through the artificial valve leaflet and penetrates into the heart tissue, the fitting component is located in the middle area of ​​the artificial valve leaflet close to the native valve ring, so that the middle area is in close contact with the atrial tissue or the native valve leaflet.

2. A repair system for improving heart valve coaptation according to claim 1, characterized in that: The abutment member includes a first developing ring, a second developing ring, and an elastic member arranged between the first developing ring and the second developing ring. The first developing ring is provided with a buffer structure. The second guide wire is tightened, the first developing ring abuts against the artificial valve leaflet, and pushes the second tube to compress the elastic member. The first developing ring and the second developing ring are fitted together, and the control rod is rotated to allow the threaded needle to pass through the artificial valve leaflet and penetrate into the heart tissue.

3. A repair system for improving heart valve coaptation according to claim 2, characterized in that: The artificial valve leaflet includes a clasping piece and a fixing bracket arranged at the distal end of the clasping piece, the fixing bracket is provided with an anchoring area, and the first tube and the second tube are detachably connected to the anchoring area through the first guide wire and the second guide wire respectively.

4. A repair system for improving heart valve coaptation according to claim 1, characterized in that: The connecting portion is sleeved on the root of the threaded needle, and the connecting portion has a preset shape.

5. A repair system for improving heart valve coaptation according to claim 3, characterized in that: When the first developing ring is in close contact with the anchoring area, the first tube is withdrawn so that the connecting portion returns to a preset shape, and the lower pressing plate is located in the middle area of ​​the matching plate close to the autologous valve ring.

6. A repair system for improving heart valve coaptation according to claim 5, characterized in that: The longer the stroke of the threaded needle penetrating the heart tissue is, the shorter the distance between the pressing portion and the atrial wall or the native valve leaflet is.

7. A repair system for improving heart valve coaptation according to claim 5, characterized in that: The pressing part comprises a frame and a fabric layer covering the frame, wherein the frame is composed of a plurality of metal wires and arranged in a grid structure, and the longitudinal arrangement density of the metal wires is greater than the transverse arrangement density.

8. A repair system for improving heart valve coaptation according to claim 7, characterized in that: One end of the anti-twist component is fixed to the anchoring area, and the other end of the anti-twist component is fixed to the lower pressing plate, wherein the anti-twist component includes a first anti-twist component and a second anti-twist component respectively arranged on the left and right sides of the lower pressing plate, so that when the threaded needle rotates, the lower pressing plate remains stationary in the circumferential direction.

9. A repair system for improving heart valve coaptation according to claim 8, characterized in that: An arched rod is provided on the mating piece, and the area between the proximal end of the fixing bracket and the rod is called a side leakage prevention area, and both sides of the side leakage prevention area are respectively provided with a backward curled recessed portion.

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