Female antibacterial liquid containing lucid ganoderma extract and preparation method of female antibacterial liquid

Abstract

The invention discloses female antibacterial liquid containing a lucid ganoderma extract and a preparation method of the female antibacterial liquid. The female antibacterial liquid is prepared from the following raw materials in percentage by weight: 0.134% of parachlorometaxylenol, 1.1% of a radix sophorae flavescentis extract, 20% of a malt extract, 5% of the lucid ganoderma extract, 42% of a grape fruit extract, 24.52% of olive oil, 5% of simmondsia chinensis seed oil, 0.45% of zedoary turmeric oil, 1.5% of eucalyptus oil and 0.3% of borneol. The ganoderma lucidum extract is extracted by adopting a water extraction and alcohol precipitation method, and the content of ganoderma lucidum polysaccharide is not less than 20%; the grape fruit extract is extracted by adopting a supercritical carbon dioxide extraction technology; the sophora flavescens extract is extracted by adopting an ethanol extraction method, and the matrine content is not less than 0.5%. The invention has the advantages that: the anti-bacterial and nourishing effects are integrated, the anti-bacterial effect is improved and the nourishing and protecting effects of the product are enhanced by carefully selecting a plurality of natural plant extracts and optimizing the proportion, and the anti-bacterial and nourishing mask is suitable for being used on sensitive skin; meanwhile, the stability and the use experience of the product are ensured by the fine preparation process, and the overall stability and the safety of the product are improved.

Description

Technical Field

[0001] The invention relates to the technical field of personal care products, in particular to a female antibacterial liquid containing ganoderma lucidum extract and a preparation method thereof. Background Art

[0003] As a traditional precious Chinese herbal medicine, Ganoderma lucidum has extremely high medicinal value. It is rich in polysaccharides, triterpenoid compounds and various amino acids and other active ingredients, which have multiple biological activities such as enhancing immunity, anti-tumor, anti-oxidation and anti-inflammatory. In recent years, the application research of Ganoderma lucidum extract in the field of female intimate care has gradually deepened, and it has been found that it has significant effects in inhibiting and killing harmful microorganisms inside and outside the vagina, promoting wound healing, preventing or eliminating inflammation, and accelerating the recovery of lesions.

[0004] However, there are many types of female antibacterial liquids on the market, but not all products can effectively extract and utilize the active ingredients of Chinese herbal medicines such as Ganoderma lucidum. Traditional extraction methods often have problems such as low efficiency, large loss of active ingredients, and poor product stability. Therefore, it is particularly important to develop an efficient, stable, and easy-to-prepare female antibacterial liquid containing Ganoderma lucidum extract. Summary of the invention

[0005] The technical problem to be solved by the present invention is to overcome the above technical defects and provide a female antibacterial liquid containing Ganoderma lucidum extract and a preparation method thereof.

[0006] In order to solve the above problems, the technical solution of the present invention is a female antibacterial liquid containing Ganoderma lucidum extract, comprising the following raw materials in percentage by weight:

[0007] p-Chloro-m-dimethylphenol, 0.134%;

[0008] Sophora flavescens extract, 1.1%;

[0009] malt extract, 20%;

[0010] Ganoderma lucidum extract, 5%;

[0011] Grape fruit extract, 42%;

[0012] Olive oil, 24.52%;

[0013] Jojoba seed oil, 5%;

[0014] Curcuma zedoaria oil, 0.45%;

[0015] Eucalyptus oil, 1.5%;

[0016] Borneol, 0.3%.

[0017] Furthermore, the grape fruit extract is extracted from fresh grape fruit using supercritical carbon dioxide extraction technology to retain more natural active ingredients.

[0018] Furthermore, the ganoderma lucidum extract is derived from ganoderma lucidum fruiting bodies, the ganoderma lucidum extract is extracted by water extraction and alcohol precipitation method, and the ganoderma lucidum polysaccharide content in the extract is not less than 20%.

[0019] Furthermore, the Sophora flavescens extract is derived from the root of Sophora flavescens, and the Sophora flavescens extract is extracted by ethanol, and the matrine content is not less than 0.5%.

[0020] A method for preparing a female antibacterial liquid containing a ganoderma lucidum extract comprises the following steps:

[0021] S1. Evenly mix the Ganoderma lucidum extract, Sophora flavescens extract, malt extract and grape fruit extract according to a certain proportion;

[0022] S2, add olive oil, jojoba seed oil, zedoary oil, eucalyptus oil and borneol, and stir until completely dissolved;

[0023] S3, adding para-chloro-meta-xylenol to the mixture obtained in step S2, and stirring evenly;

[0024] S4, filtering the mixture obtained in step S3 through a microfiltration membrane to remove impurities;

[0025] S5. Aseptically fill the liquid obtained in step S4 to obtain the final product.

[0026] Furthermore, the mixing temperature in step S1 is controlled between 40° C. and 50° C. to ensure that the active ingredients are not destroyed.

[0027] Furthermore, the pore size of the microfiltration membrane in step S4 is not greater than 0.22 μm to ensure the sterility of the product.

[0028] Furthermore, in step S1, the concentrated Ganoderma lucidum extract is left to stand at 2-8° C. for 20-40 days to promote its stability.

[0029] Furthermore, the stirring time in step S2 is 30 minutes to 1 hour, and the stirring speed is 500 rpm to 1000 rpm.

[0030] The advantages of the present invention compared with the prior art are:

[0031] 1. The present invention provides a female antibacterial liquid containing ganoderma lucidum extract and a preparation method thereof. The ganoderma lucidum extract is rich in ganoderma lucidum polysaccharide and has good immunomodulatory and antioxidant effects; the grape fruit extract retains more natural active ingredients through supercritical carbon dioxide extraction technology, which is helpful for vaginal repair and anti-oxidation; the malt extract can provide rich vitamins and minerals and promote vaginal health. The combination of these ingredients not only improves the antibacterial effect, but also enhances the nourishing and protective effects of the product, restores vaginal elasticity, and is suitable for use by postpartum people;

[0032] 2. The present invention provides a female antibacterial liquid containing ganoderma lucidum extract and a preparation method thereof. In the extraction stage, the ganoderma lucidum extract adopts the water extraction and alcohol precipitation method to ensure the high content of ganoderma lucidum polysaccharide; the grape fruit extract adopts the supercritical carbon dioxide extraction technology to retain the active ingredients to the maximum extent. In the preparation process, the mixing temperature is controlled between 40°C and 50°C to ensure that the active ingredients will not be destroyed by high temperature; by using microfiltration membrane filtration, the sterility and purity of the final product are ensured. These meticulous process controls not only ensure the quality of the product, but also improve the stability and user experience of the product. DETAILED DESCRIPTION

[0033] The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present disclosure. Instead, they are merely examples of devices consistent with some aspects of the present disclosure as detailed in the appended claims.

[0034] The technical solutions in the embodiments of the present invention are clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0035] A female antibacterial liquid containing ganoderma lucidum extract, comprising the following raw materials in percentage by weight:

[0036] p-Chloro-m-dimethylphenol, 0.134%;

[0037] Sophora flavescens extract, 1.1%;

[0038] malt extract, 20%;

[0039] Ganoderma lucidum extract, 5%;

[0040] Grape fruit extract, 42%;

[0041] Olive oil, 24.52%;

[0042] Jojoba seed oil, 5%;

[0043] Curcuma zedoaria oil, 0.45%;

[0044] Eucalyptus oil, 1.5%;

[0045] Borneol, 0.3%.

[0046] Furthermore, the ganoderma lucidum extract is derived from ganoderma lucidum fruiting body, the ganoderma lucidum extract is extracted by water extraction and alcohol precipitation method, and the ganoderma lucidum polysaccharide content in the extract is not less than 20%.

[0047] Furthermore, grape fruit extract is extracted from fresh grape fruit using supercritical carbon dioxide extraction technology to retain more natural active ingredients.

[0048] Furthermore, the Sophora flavescens extract is derived from the root of Sophora flavescens, the Sophora flavescens extract is extracted by ethanol, and the matrine content is not less than 0.5%.

[0049] A method for preparing a female antibacterial liquid containing a ganoderma lucidum extract comprises the following steps:

[0050] S1. Evenly mix the Ganoderma lucidum extract, Sophora flavescens extract, malt extract and grape fruit extract according to a certain proportion;

[0051] S2, add olive oil, jojoba seed oil, zedoary oil, eucalyptus oil and borneol, and stir until completely dissolved;

[0052] S3, adding para-chloro-meta-xylenol to the mixture obtained in step S2, and stirring evenly;

[0053] S4, filtering the mixture obtained in step S3 through a microfiltration membrane to remove impurities;

[0054] S5. Aseptically fill the liquid obtained in step S4 to obtain the final product.

[0055] Furthermore, in step S1, the concentrated Ganoderma lucidum extract is allowed to stand at 2-8° C. for 20-40 days to promote its stability.

[0056] Furthermore, the mixing temperature in step S1 is controlled between 40° C. and 50° C. to ensure that the active ingredients are not destroyed.

[0057] Furthermore, the stirring time in step S2 is 30 minutes to 1 hour, and the stirring speed is 500 rpm to 1000 rpm.

[0058] Furthermore, the pore size of the microfiltration membrane in step S4 is no greater than 0.22 μm to ensure the sterility of the product.

[0059] In specific use, a female antibacterial liquid containing Ganoderma lucidum extract includes the following raw materials in percentage by weight:

[0060] p-Chloro-m-dimethylphenol, 0.134%;

[0061] Sophora flavescens extract, 1.1%;

[0062] malt extract, 20%;

[0063] Ganoderma lucidum extract, 5%;

[0064] Grape fruit extract, 42%;

[0065] Olive oil, 24.52%;

[0066] Jojoba seed oil, 5%;

[0067] Curcuma zedoaria oil, 0.45%;

[0068] Eucalyptus oil, 1.5%;

[0069] Borneol, 0.3%.

[0070] Ganoderma lucidum fruiting bodies are used as raw materials and are extracted by water extraction and alcohol precipitation. During the extraction process, the Ganoderma lucidum fruiting bodies are first crushed and then extracted with water. The extraction temperature is 90°C and the extraction time is 2 hours. After the extract is filtered, 95% ethanol is added until the alcohol content reaches 80%, and the extract is left overnight. The precipitate is removed by filtering the next day, and the filtered liquid is concentrated under reduced pressure to obtain a Ganoderma lucidum extract. It is tested that the Ganoderma lucidum polysaccharide content is not less than 20%.

[0071] Fresh grapes are used as raw materials and supercritical carbon dioxide extraction technology is used for extraction. The extraction pressure is 30MPa, the temperature is 40℃, the carbon dioxide flow rate is 1kg / h, and the extraction time lasts for 2 hours to obtain grape fruit extract, which retains more natural active ingredients.

[0072] The root of Sophora flavescens is used as raw material and an ethanol extraction method is adopted. During the extraction process, the root of Sophora flavescens is crushed and extracted with 70% ethanol at an extraction temperature of 60°C for 3 hours. The extract is filtered and concentrated to obtain a Sophora flavescens extract. The matrine content is not less than 0.5% after testing.

[0073] Ganoderma lucidum extract, Sophora flavescens extract, malt extract and grape fruit extract are mixed evenly in proportion, and the concentrated Ganoderma lucidum extract is left to stand at 4°C for 30 days to promote its stability. The mixing temperature is controlled at 45°C to ensure that the active ingredients are not destroyed.

[0074] Add olive oil, jojoba seed oil, zedoary turmeric oil, eucalyptus oil and borneol, stir until completely dissolved, the stirring time is 45 minutes, the stirring speed is 800 rpm, add p-chloro-m-xylenol to the mixture, and stir evenly.

[0075] The mixture obtained in the above steps is filtered through a microfiltration membrane to remove impurities. The pore size of the microfiltration membrane is 0.22 μm to ensure the sterility of the product. The obtained liquid is aseptically filled to obtain the final product.

[0076] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0077] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0078] The present invention and its implementation methods are described above, and such description is not restrictive, and the actual structure is not limited thereto. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design structures and embodiments similar to the technical solution without creativity, which should all fall within the protection scope of the present invention.

Claims

1. A female antibacterial liquid containing Ganoderma lucidum extract, characterized in that: The raw material composition includes the following weight percentages: p-Chloro-m-dimethylphenol, 0.134%; Sophora flavescens extract, 1.1%; malt extract, 20%; Ganoderma lucidum extract, 5%; Grape fruit extract, 42%; Olive oil, 24.52%; Jojoba seed oil, 5%; Curcuma zedoaria oil, 0.45%; Eucalyptus oil, 1.5%; Borneol, 0.3%.

2. The female antibacterial liquid containing Ganoderma lucidum extract according to claim 1, characterized in that: The ganoderma lucidum extract is derived from ganoderma lucidum fruiting bodies, is extracted by water extraction and alcohol precipitation, and the ganoderma lucidum polysaccharide content in the extract is not less than 20%.

3. The female antibacterial liquid containing Ganoderma lucidum extract according to claim 1, characterized in that: The grape fruit extract is extracted from fresh grape fruit by using supercritical carbon dioxide extraction technology to retain more natural active ingredients.

4. The antibacterial liquid for women containing Ganoderma lucidum extract according to claim 1, characterized in that: The sophora flavescens extract is derived from the root of sophora flavescens, and the sophora flavescens extract is extracted by ethanol, and the matrine content is not less than 0.5%.

5. A method for preparing a female antibacterial liquid containing a Ganoderma lucidum extract, characterized in that: The following steps are involved: S1. Evenly mix the Ganoderma lucidum extract, Sophora flavescens extract, malt extract and grape fruit extract according to a certain proportion; S2, add olive oil, jojoba seed oil, zedoary oil, eucalyptus oil and borneol, and stir until completely dissolved; S3, adding para-chloro-meta-xylenol to the mixture obtained in step S2, and stirring evenly; S4, filtering the mixture obtained in step S3 through a microfiltration membrane to remove impurities; S5. Aseptically fill the liquid obtained in step S4 to obtain the final product.

6. The method for preparing a female antibacterial liquid containing a Ganoderma lucidum extract according to claim 5, characterized in that: In the step S1, the concentrated Ganoderma lucidum extract is left to stand at 2-8° C. for 20-40 days to promote its stability.

7. The method for preparing a female antibacterial liquid containing a Ganoderma lucidum extract according to claim 5, characterized in that: The mixing temperature in step S1 is controlled between 40° C. and 50° C. to ensure that the active ingredients are not destroyed.

8. The method for preparing a female antibacterial liquid containing a Ganoderma lucidum extract according to claim 5, characterized in that: The stirring time in step S2 is 30 minutes to 1 hour, and the stirring speed is 500 rpm to 1000 rpm.

9. The method for preparing a female antibacterial liquid containing a Ganoderma lucidum extract according to claim 5, characterized in that: The pore size of the microfiltration membrane in step S4 is no greater than 0.22 μm to ensure the sterility of the product.