Microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia

Abstract

The invention relates to the technical field of microwave-assisted extraction, in particular to a traditional Chinese medicine effective component microwave-assisted extraction system for treating myopia, which specifically comprises a traditional Chinese medicine data acquisition module, a traditional Chinese medicine characteristic model construction module, an extraction correlation coefficient calculation module, a to-be-extracted traditional Chinese medicine matching module and a microwave-assisted extraction monitoring module, extracting medicinal material characteristics of each medicinal material in the combined medicinal material; quantifying the relationship between the medicinal material characteristics and the extraction effect of each medicinal material in the combined traditional Chinese medicine; and monitoring the extraction efficiency of the effective components in the extraction process in real time and executing a corresponding extraction parameter feedback adjustment strategy. The problems that in the prior art, in the extraction process of traditional Chinese medicine effective components for myopia treatment, due to different medicine batches, the quality control difficulty of the medicine effective components is large, and a large amount of medicinal materials are wasted are solved.

Description

Technical Field

[0001] The invention relates to the technical field of microwave-assisted extraction, in particular to a microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia. Background Art

[0002] With the increasing incidence of myopia, traditional Chinese medicine (TCM) has shown potential in the treatment of myopia and eye health. Some active ingredients of TCM are believed to help improve vision and slow the progression of myopia. Microwave-assisted extraction (MAE) improves the extraction efficiency of active ingredients of TCM by microwave heating, which has the advantages of rapidity, high efficiency and easy operation, but inconsistent batches of TCM may lead to unstable concentrations of active ingredients during the extraction process. Batch differences in TCM (such as source and processing) can lead to variations in the content of active ingredients, which makes it difficult to maintain consistency in ingredient concentration during the extraction process and increases the difficulty of production quality control. Existing microwave extraction systems are insufficient in dealing with batch differences and cannot effectively stabilize the concentration of active ingredients in the extract. Therefore, an innovative microwave-assisted extraction system is needed that can dynamically adjust conditions during the extraction process to ensure the quality and stability of the drug.

[0003] In the existing disclosed invention technologies, for example, the patent with publication number CN116083166A discloses a system and method for microwave-assisted extraction of animal fats and oils. The system includes a microwave extraction unit, a cooling unit, a waste discharge unit and an automated control system unit. The microwave extraction unit performs microwave treatment on the animal fats and oils and separates solid and liquid products; the cooling unit cools the heat energy generated during the extraction; the waste discharge unit discharges the moisture generated during the extraction and purifies the waste gas and discharges it; and the automated control system unit controls the above system.

[0004] The above patents perform differently when processing different types of animal fats and oils, have poor adaptability to different types of fats and oils, and cannot solve quality control problems when used on a large scale. Summary of the invention

[0005] The technical problem to be solved by the present invention is that in the prior art, in the process of extracting effective ingredients of traditional Chinese medicine for the treatment of myopia, the concentration of effective ingredients of traditional Chinese medicine is difficult to control in the actual extraction process due to different batches of drugs, which makes the production quality control of drugs difficult. A microwave-assisted extraction system for effective ingredients of traditional Chinese medicine for the treatment of myopia is proposed.

[0006] In order to achieve the above object, the microwave-assisted extraction system of effective components of traditional Chinese medicine for treating myopia of the present invention comprises the following modules:

[0007] Traditional Chinese medicine data collection module, traditional Chinese medicine characteristic model construction module, extraction correlation coefficient calculation module, traditional Chinese medicine matching module to be extracted and microwave-assisted extraction monitoring module;

[0008] The traditional Chinese medicine data collection module is used to collect basic medicinal material data related to the selected traditional Chinese medicine;

[0009] The Chinese medicine characteristic model building module is used to build a Chinese medicine characteristic model, identify the contribution of the effective ingredients in the medicinal materials to the treatment of myopia, and extract the medicinal material characteristics of each medicinal material with contributing ingredients in the combined medicinal materials;

[0010] The extraction correlation coefficient calculation module is used to quantify the relationship between the medicinal material characteristics of each medicinal material in the combined Chinese medicine and its extraction effect;

[0011] The Chinese medicine matching module to be extracted is used to intelligently match the proportion of medicinal ingredients in the combined medicinal materials according to user needs and the Chinese medicine characteristic model;

[0012] The microwave-assisted extraction monitoring module is used to monitor the extraction efficiency of the effective components in the extraction process in real time and to execute the corresponding extraction parameter feedback adjustment strategy.

[0013] Specifically, the traditional Chinese medicine data acquisition module includes: a physical property acquisition unit and a microwave response characteristic acquisition unit; the physical property acquisition unit is used to obtain cell wall thickness data, medicinal material porosity data, medicinal material surface area data and medicinal material surface scanning image data in traditional Chinese medicine; the microwave response characteristic acquisition unit is used to collect the medicinal material ratio of each medicinal material in the historical extraction combination medicinal material, the microwave-assisted extraction parameters in the historical extraction process of the combination medicinal material and the concentration of each effective ingredient obtained by the combination medicinal material extraction.

[0014] Specifically, the traditional Chinese medicine characteristic model construction module is used to run the following specific steps:

[0015] S21: extracting the basic data of medicinal materials collected in the traditional Chinese medicine data collection module, and calculating the derived characteristic factors of the medicinal materials, wherein the derived characteristic factors include: a derived characteristic factor of cell wall thickness, a derived characteristic factor of porosity, and a derived characteristic factor of medicinal material surface area;

[0016] Among them, the cell wall thickness derived characteristic factor F cell The calculation strategy is:

[0017] d is the thickness of the medicinal material cell wall, d0 is the target thickness of the medicinal material cell wall, k is the influence of the cell wall thickness on the medicinal material extraction efficiency, and c represents the pretreatment factor;

[0018] Porosity-derived characteristic factor F po The calculation strategy is:

[0019] K is the surface porosity of the medicinal material; ρ is the density of the medicinal material; p is the particle size of the medicinal material;

[0020] Surface area-derived characteristic factor Fsa The calculation strategy is:

[0021] N is the total number of pixels in the scanned image data of the medicinal material surface; S is the surface area of ​​the medicinal material, XS n Indicates the pixel value of the nth pixel in the scanned image data of the medicinal material surface, XS max , XS min They are the maximum pixel value point and the minimum pixel value point in the scanned image data of the medicinal material surface respectively;

[0022] S22: extracting the medicinal material ratio of each medicinal material in the historical extraction of the combined medicinal materials, the microwave-assisted extraction parameters in the historical extraction process of the combined medicinal materials, and the concentrations of each effective ingredient obtained by the combined medicinal materials extraction, and combining the data to form a historical extraction feature vector set of the combined medicinal materials, and at the same time dividing the historical extraction feature vector set of the combined medicinal materials into a training set and a test set in a ratio of 9:1.

[0023] Specifically, the operation strategy of the traditional Chinese medicine characteristic model construction module also includes:

[0024] S23: combining the derived characteristic factors of a single type of medicinal material into a characteristic vector form, and obtaining a basic characteristic vector set of each type of medicinal material in the combined medicinal material;

[0025] S24: constructing a Chinese medicine feature model, wherein the Chinese medicine feature model comprises: an input layer, a hidden layer and an output layer; the input of the Chinese medicine feature model is a basic feature vector set of each type of medicinal material in the combined medicinal material and a historically extracted feature vector set of the combined medicinal material; the hidden layer comprises 8 10×10 convolution kernels; the output of the output layer is a predicted value of the concentration of each active ingredient extracted from the combined medicinal material;

[0026] S25: standardizing the basic feature vector set of each type of medicinal material in the combined medicinal material and the historically extracted feature vector set of the combined medicinal material, and extracting medicinal material features using a traditional Chinese medicine feature model;

[0027] S26: Use the neurons in the hidden layer to perform convolution calculations, specifically:

[0028]

[0029] in, is the output of the jth neuron in the lth hidden layer;

[0030] is the activation value of the i-th neuron in the l-1-th hidden layer; is the bias term of the jth neuron in the lth hidden layer; is the contribution weight from the i-th neuron in the l-1th hidden layer to the j-th neuron in the l-th hidden layer; m is the total number of neurons in the hidden layer;

[0031] S27: Testing the traditional Chinese medicine feature model using a test set, and stopping the training when the sum of the prediction accuracies reaches convergence.

[0032] Specifically, the operation strategy of the extraction correlation coefficient calculation module includes:

[0033] S31: extracting the parent curve of the predicted value of each effective component concentration versus extraction time, and the parent curve of the microwave-assisted extraction power and the microwave-assisted extraction temperature versus extraction time;

[0034] S32: intercepting multiple combined Chinese medicine microwave-assisted extraction processes whose predicted values ​​of the concentration of each active ingredient differ by no more than 5%, and synchronously extracting sub-curves of predicted values ​​of the concentration of each active ingredient versus extraction time, microwave-assisted extraction power, and microwave-assisted extraction temperature versus extraction time corresponding to the multiple combined Chinese medicine microwave-assisted extraction processes obtained;

[0035] S33: separating the sub-curves of microwave-assisted extraction power and microwave-assisted extraction temperature versus extraction time in the microwave-assisted extraction process of the combined traditional Chinese medicine, taking the microwave-assisted extraction process of the combined traditional Chinese medicine corresponding to the microwave-assisted extraction power to form an interference set of microwave-assisted extraction power, taking the microwave-assisted extraction power adjustment amount in the interference set of microwave-assisted extraction power and the change amount of the predicted value of each active ingredient concentration in the microwave-assisted extraction process of the combined traditional Chinese medicine versus extraction time;

[0036] Among them, the set of microwave-assisted extraction power adjustment amounts is:

[0037] Where V is the total number of combined Chinese medicines in set A; The superscript g represents the microwave-assisted extraction power corresponding to the microwave-assisted extraction process of this combined Chinese medicine, and the subscript represents the microwave-assisted extraction process of the vth combined Chinese medicine. That is, the microwave-assisted extraction power of the vth combined traditional Chinese medicine microwave-assisted extraction process;

[0038] Among them, in the interference set of microwave-assisted extraction power, the effective amount set of the predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the vth combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the vth combination of traditional Chinese medicines;

[0039] S34: introducing the set A of microwave-assisted extraction power adjustment amounts and the effective amount set A′ of predicted values ​​of concentrations of each effective component corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine over time into the extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction power, and calculating and obtaining the extraction correlation coefficient corresponding to the microwave-assisted extraction power. The extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction power is specifically as follows:

[0040] in, They are respectively the set A of microwave-assisted extraction power adjustment values ​​and the mean data of the effective set A′ of predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time.

[0041] Specifically, the operation strategy of the extraction correlation coefficient calculation module also includes:

[0042] S35: The curve of microwave-assisted extraction temperature and extraction time obtained during microwave-assisted extraction of combined Chinese medicine;

[0043] S36: intercepting the microwave-assisted extraction process of the combined traditional Chinese medicine with the same microwave-assisted extraction power, setting it as the interference set of microwave-assisted extraction temperature, taking the adjustment amount of the microwave-assisted extraction temperature in the interference set of microwave-assisted extraction temperature and the change amount of the predicted value of each effective component concentration in the microwave-assisted extraction process of the combined traditional Chinese medicine with the extraction time;

[0044] Among them, the set of microwave-assisted extraction temperature adjustment amounts is:

[0045] Where U is the total number of combined Chinese medicines in set B; The superscript Te of represents the microwave-assisted extraction temperature corresponding to the microwave-assisted extraction process of this combined Chinese medicine, and the subscript Te represents the microwave-assisted extraction process of the u-th combined Chinese medicine. That is, the microwave-assisted extraction temperature of the u-th combined traditional Chinese medicine microwave-assisted extraction process;

[0046] Among them, in the interference set of microwave-assisted extraction temperature, the effective amount set of the predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the u-th combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the u-th combination of traditional Chinese medicines;

[0047] S37: The set B of microwave-assisted extraction temperature adjustment amounts and the effective amount set B′ of predicted values ​​of concentrations of each effective component corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine over time are introduced into the extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction temperature, and the extraction correlation coefficient corresponding to the microwave-assisted extraction temperature is calculated and obtained. The extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction temperature is specifically as follows:

[0048] in, They are respectively the set B of microwave-assisted extraction temperature adjustment values ​​and the mean data of the effective amount set B′ of predicted values ​​of each effective component concentration corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time.

[0049] Specifically, the operation strategy of the extraction correlation coefficient calculation module also includes:

[0050] S38: Extract the derived characteristic factors of the medicinal materials and calculate the comprehensive derived characteristic factor φ of the combined medicinal materials. The calculation formula is: Where x is a subscript, indicating the xth type of medicinal material in the combined medicinal material, X is the total number of medicinal material categories in the combined medicinal material; α1, α2, and α3 are the comprehensive proportional coefficients of the derived characteristic factors of the medicinal materials respectively; F cell,x ,F po,x ,F sa,x They represent the cell wall thickness-derived characteristic factor, porosity-derived characteristic factor and medicinal material surface area-derived characteristic factor of the x-th type of medicinal material, respectively;

[0051] S39: microwave-assisted extraction process of combined traditional Chinese medicine with the same microwave-assisted extraction temperature and microwave-assisted extraction power;

[0052] Taking the combined traditional Chinese medicine microwave-assisted extraction process corresponding to the comprehensive derived characteristic factors of the combined medicinal materials, an interference set of the comprehensive derived characteristic factors of the combined medicinal materials is formed;

[0053] Take the comprehensive derived characteristic factors in the interference set of the comprehensive derived characteristic factors of the combined medicinal materials and the changes of the predicted values ​​of the concentrations of each effective component in the microwave-assisted extraction process of the combined Chinese medicine with the extraction time;

[0054] Among them, the set of comprehensive derived characteristic factors is: Where E is the total number of combined Chinese medicines in the set Φ, The superscript φ represents the comprehensive derivative characteristic factor corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscript φ represents the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines. That is, the comprehensive derived characteristic factor of the microwave-assisted extraction process of the e-th combined traditional Chinese medicine;

[0055] Among them, in the interference set of the comprehensive derived characteristic factors of the combined medicinal materials, the effective amount set of the predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of the combined Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines;

[0056] S310: introducing the set of comprehensive derived characteristic factors Φ of the combined medicinal materials and the effective amount set W′ of the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of the combined Chinese medicine into the extraction correlation coefficient calculation strategy corresponding to the comprehensive derived characteristic factors, and calculating and obtaining the extraction correlation coefficient corresponding to the comprehensive derived characteristic factors, the extraction correlation coefficient γ corresponding to the comprehensive derived characteristic factors φ The specific calculation strategy is:

[0057] in, They are respectively the set Φ of the comprehensive derived characteristic factors of the combined medicinal materials and the mean of the data in the effective amount set W′ of the predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of the combined Chinese medicine changing with time.

[0058] Specifically, the microwave-assisted extraction monitoring module includes an extraction efficiency calculation unit, an extraction efficiency monitoring unit and a feedback adjustment unit;

[0059] The calculation strategy of the extraction efficiency η of the combined medicinal material effective components in the extraction efficiency calculation unit is specifically as follows:

[0060]

[0061] Among them, n t The concentration of the active ingredient extracted from the combined medicinal materials being extracted; mb is the target value of the active ingredient in the combined medicinal material being extracted;

[0062] Extract the correlation coefficient for the whole,

[0063] Among them, ε1, ε2, and ε3 are the influencing proportional factors of the extracted correlation coefficients.

[0064] Specifically, the monitoring strategy of the extraction efficiency monitoring unit includes:

[0065] S51: monitoring the effective ingredient concentration difference Δnd, presetting the minimum effective threshold of the effective ingredient, and when the effective ingredient concentration difference Δnd is greater than the minimum effective threshold, extending the microwave-assisted extraction time and continuing monitoring, wherein:

[0066] S52: synchronously calculating the difference between the extraction efficiency η of the combined medicinal material effective components and the target extraction efficiency η0 as Δη, and presetting the maximum tolerance difference of the extraction efficiency;

[0067] When the difference Δη is greater than the maximum tolerable difference in extraction efficiency, the original microwave-assisted extraction power is increased first, and the extraction temperature of the microwave-assisted extraction container is monitored simultaneously. When the average temperature during the monitoring period exceeds the maximum pyrolysis temperature of the combined medicinal materials, the power is immediately reduced to the original microwave-assisted extraction power, and the staff is notified to manually adjust the microwave-assisted power.

[0068] A storage medium stores instructions, and when a computer reads the instructions, the computer is enabled to execute the microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia.

[0069] An electronic device comprises a memory, a processor and a computer program stored in the memory and executable on the processor. When the processor executes the computer program, the microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia is realized.

[0070] Compared with the prior art, the technical effects of the present invention are as follows:

[0071] 1. The traditional Chinese medicine data acquisition module in the present invention collects comprehensive data through the physical property acquisition unit and the microwave response characteristic acquisition unit. The system can obtain more comprehensive medicinal material data, including cell wall thickness, porosity, medicinal material surface area, etc., and construct a traditional Chinese medicine characteristic model through the calculation of derived characteristic factors and the establishment of characteristic vector sets, providing a basis for subsequent extraction efficiency optimization.

[0072] 2. The present invention accurately quantifies the relationship between medicinal material characteristics and extraction effect. By extracting the changes in extraction efficiency under different parameters, the influence of different parameters on microwave-assisted extraction efficiency is quantified, solving the problem that the traditional method lacks accurate quantification means, resulting in unstable extraction effect or failure to fully utilize the effective ingredients of medicinal materials.

[0073] 3. The extraction efficiency monitoring unit in the present invention ensures the high efficiency and stability of the extraction process through precise efficiency calculation and real-time data monitoring. The automatic adjustment function effectively avoids the problems of overheating or inefficient extraction, thereby improving the overall extraction effect and the operational reliability of the system. BRIEF DESCRIPTION OF THE DRAWINGS

[0074] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative labor.

[0075] in:

[0076] Figure 1 It is a schematic structural diagram of a microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to the present invention;

[0077] Figure 2 It is a structural schematic diagram of the microwave-assisted extraction monitoring module of the present invention. DETAILED DESCRIPTION

[0078] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0079] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0080] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0081] Embodiment 1:

[0082] like Figure 1 , 2 As shown, the microwave-assisted extraction system of effective components of traditional Chinese medicine for treating myopia according to the embodiment of the present invention is as follows: Figure 1 As shown, it includes the following specific modules:

[0083] Traditional Chinese medicine data collection module, traditional Chinese medicine characteristic model construction module, extraction correlation coefficient calculation module, traditional Chinese medicine matching module to be extracted and microwave-assisted extraction monitoring module;

[0084] The traditional Chinese medicine data acquisition module includes: a physical property acquisition unit and a microwave response characteristic acquisition unit; the physical property acquisition unit is used to obtain cell wall thickness data, medicinal material porosity data, medicinal material surface area data and medicinal material surface scanning image data in traditional Chinese medicine; the microwave response characteristic acquisition unit is used to collect the medicinal material ratio of each medicinal material in the historical extraction combination medicinal material, the microwave-assisted extraction parameters in the historical extraction process of the combination medicinal material and the concentration of each effective ingredient obtained by the combination medicinal material extraction.

[0085] The Chinese medicine characteristic model building module is used to build a Chinese medicine characteristic model, identify the contribution of the effective ingredients in the medicinal materials to the treatment of myopia, and extract the medicinal material characteristics of each medicinal material with contributing ingredients in the combined medicinal materials;

[0086] The Chinese medicine characteristic model construction module is used to run the following specific steps:

[0087] S21: extracting the basic data of medicinal materials collected in the traditional Chinese medicine data collection module, and calculating the derived characteristic factors of the medicinal materials, wherein the derived characteristic factors include: a derived characteristic factor of cell wall thickness, a derived characteristic factor of porosity, and a derived characteristic factor of medicinal material surface area;

[0088] Among them, the cell wall thickness derived characteristic factor F cell The calculation strategy is:

[0089] d is the thickness of the medicinal material cell wall, d0 is the target thickness of the medicinal material cell wall, k is the influence of the cell wall thickness on the medicinal material extraction efficiency, and c represents the pretreatment factor;

[0090] Porosity-derived characteristic factor F po The calculation strategy is:

[0091] K is the surface porosity of the medicinal material; ρ is the density of the medicinal material; p is the particle size of the medicinal material;

[0092] Surface area-derived characteristic factor F sa The calculation strategy is:

[0093] N is the total number of pixels in the scanned image data of the medicinal material surface; S is the surface area of ​​the medicinal material, XS n Indicates the pixel value of the nth pixel in the scanned image data of the medicinal material surface, XS max , XS min They are the maximum pixel value point and the minimum pixel value point in the scanned image data of the medicinal material surface respectively;

[0094] S22: extracting the medicinal material ratio of each medicinal material in the historical extraction of the combined medicinal materials, the microwave-assisted extraction parameters in the historical extraction process of the combined medicinal materials, and the concentrations of each effective ingredient obtained by the combined medicinal materials extraction, and combining the data to form a historical extraction feature vector set of the combined medicinal materials, and at the same time dividing the historical extraction feature vector set of the combined medicinal materials into a training set and a test set in a ratio of 9:1.

[0095] The operation strategy of the traditional Chinese medicine characteristic model construction module also includes:

[0096] S23: combining the derived characteristic factors of a single type of medicinal material into a characteristic vector form, and obtaining a basic characteristic vector set of each type of medicinal material in the combined medicinal material;

[0097] S24: constructing a Chinese medicine feature model, wherein the Chinese medicine feature model comprises: an input layer, a hidden layer and an output layer; the input of the Chinese medicine feature model is a basic feature vector set of each type of medicinal material in the combined medicinal material and a historically extracted feature vector set of the combined medicinal material; the hidden layer comprises 8 10×10 convolution kernels; the output of the output layer is a predicted value of the concentration of each active ingredient extracted from the combined medicinal material;

[0098] S25: standardizing the basic feature vector set of each type of medicinal material in the combined medicinal material and the historically extracted feature vector set of the combined medicinal material, and extracting medicinal material features using a traditional Chinese medicine feature model;

[0099] S26: Use the neurons in the hidden layer to perform convolution calculations, specifically:

[0100]

[0101] in, is the output of the jth neuron in the lth hidden layer;

[0102] is the activation value of the i-th neuron in the l-1-th hidden layer; is the bias term of the jth neuron in the lth hidden layer; is the contribution weight from the i-th neuron in the l-1th hidden layer to the j-th neuron in the l-th hidden layer; m is the total number of neurons in the hidden layer;

[0103] S27: Testing the traditional Chinese medicine feature model using a test set, and stopping the training when the sum of the prediction accuracies reaches convergence.

[0104] The extraction correlation coefficient calculation module is used to quantify the relationship between the medicinal material characteristics of each medicinal material in the combined Chinese medicine and its extraction effect;

[0105] The operation strategy of the extraction correlation coefficient calculation module includes:

[0106] S31: extracting the parent curve of the predicted value of each effective component concentration versus extraction time, and the parent curve of the microwave-assisted extraction power and the microwave-assisted extraction temperature versus extraction time;

[0107] S32: intercepting multiple combined Chinese medicine microwave-assisted extraction processes whose predicted values ​​of the concentration of each active ingredient differ by no more than 5%, and simultaneously extracting sub-curves of the predicted value of the concentration of each active ingredient versus extraction time, microwave-assisted extraction power, and microwave-assisted extraction temperature versus extraction time corresponding to the multiple combined Chinese medicine microwave-assisted extraction processes obtained by the interception;

[0108] S33: separating the sub-curves of microwave-assisted extraction power and microwave-assisted extraction temperature versus extraction time in the microwave-assisted extraction process of the combined traditional Chinese medicine, taking the microwave-assisted extraction process of the combined traditional Chinese medicine corresponding to the microwave-assisted extraction power to form an interference set of microwave-assisted extraction power, taking the microwave-assisted extraction power adjustment amount in the interference set of microwave-assisted extraction power and the change amount of the predicted value of each active ingredient concentration in the microwave-assisted extraction process of the combined traditional Chinese medicine versus extraction time;

[0109] Among them, the set of microwave-assisted extraction power adjustment amounts is:

[0110] Where V is the total number of combined Chinese medicines in set A; The superscript g represents the microwave-assisted extraction power corresponding to the microwave-assisted extraction process of this combined Chinese medicine, and the subscript represents the microwave-assisted extraction process of the vth combined Chinese medicine. That is, the microwave-assisted extraction power of the vth combined traditional Chinese medicine microwave-assisted extraction process;

[0111] Among them, in the interference set of microwave-assisted extraction power, the effective amount set of the predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the vth combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the vth combination of traditional Chinese medicines;

[0112] S34: introducing the set A of microwave-assisted extraction power adjustment amounts and the effective amount set A′ of predicted values ​​of concentrations of each effective component corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine over time into the extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction power, and calculating and obtaining the extraction correlation coefficient corresponding to the microwave-assisted extraction power. The extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction power is specifically as follows:

[0113] in, They are respectively the set A of microwave-assisted extraction power adjustment values ​​and the mean data of the effective set A′ of predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time.

[0114] The operation strategy of the extraction correlation coefficient calculation module also includes:

[0115] S35: The curve of microwave-assisted extraction temperature and extraction time obtained during microwave-assisted extraction of combined Chinese medicine;

[0116] S36: intercepting the microwave-assisted extraction process of the combined traditional Chinese medicine with the same microwave-assisted extraction power, setting it as the interference set of microwave-assisted extraction temperature, taking the adjustment amount of the microwave-assisted extraction temperature in the interference set of microwave-assisted extraction temperature and the change amount of the predicted value of each effective component concentration in the microwave-assisted extraction process of the combined traditional Chinese medicine with the extraction time;

[0117] Among them, the set of microwave-assisted extraction temperature adjustment amounts is:

[0118] Where U is the total number of combined Chinese medicines in set B; The superscript Te of represents the microwave-assisted extraction temperature corresponding to the microwave-assisted extraction process of this combined Chinese medicine, and the subscript Te represents the microwave-assisted extraction process of the u-th combined Chinese medicine. That is, the microwave-assisted extraction temperature of the u-th combined traditional Chinese medicine microwave-assisted extraction process;

[0119] Among them, in the interference set of microwave-assisted extraction temperature, the effective amount set of the predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the u-th combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the u-th combination of traditional Chinese medicines;

[0120] S37: The set B of microwave-assisted extraction temperature adjustment amounts and the effective amount set B′ of predicted values ​​of concentrations of each effective component corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine over time are introduced into the extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction temperature, and the extraction correlation coefficient corresponding to the microwave-assisted extraction temperature is calculated and obtained. The extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction temperature is specifically as follows:

[0121] in, They are respectively the set B of microwave-assisted extraction temperature adjustment values ​​and the mean data of the effective amount set B′ of predicted values ​​of each effective component concentration corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time.

[0122] The operation strategy of the extraction correlation coefficient calculation module also includes:

[0123] S38: Extract the derived characteristic factors of the medicinal materials and calculate the comprehensive derived characteristic factor φ of the combined medicinal materials. The calculation formula is: Where x is a subscript, indicating the xth type of medicinal material in the combined medicinal material, X is the total number of medicinal material categories in the combined medicinal material; α1, α2, and α3 are the comprehensive proportional coefficients of the derived characteristic factors of the medicinal materials respectively; F cell,x ,F po,x ,F sa,x They represent the cell wall thickness-derived characteristic factor, porosity-derived characteristic factor and medicinal material surface area-derived characteristic factor of the x-th type of medicinal material, respectively;

[0124] S39: microwave-assisted extraction process of combined traditional Chinese medicine with the same microwave-assisted extraction temperature and microwave-assisted extraction power;

[0125] Taking the combined traditional Chinese medicine microwave-assisted extraction process corresponding to the comprehensive derived characteristic factors of the combined medicinal materials, an interference set of the comprehensive derived characteristic factors of the combined medicinal materials is formed;

[0126] Take the comprehensive derived characteristic factors in the interference set of the comprehensive derived characteristic factors of the combined medicinal materials and the changes of the predicted values ​​of the concentrations of each effective component in the microwave-assisted extraction process of the combined Chinese medicine with the extraction time;

[0127] Among them, the set of comprehensive derived characteristic factors is: Where E is the total number of combined Chinese medicines in the set Φ, The superscript φ represents the comprehensive derivative characteristic factor corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscript φ represents the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines. That is, the comprehensive derived characteristic factor of the microwave-assisted extraction process of the e-th combined traditional Chinese medicine;

[0128] Among them, in the interference set of the comprehensive derived characteristic factors of the combined medicinal materials, the effective amount set of the predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of the combined Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines;

[0129] S310: introducing the set of comprehensive derived characteristic factors Φ of the combined medicinal materials and the effective amount set W′ of the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of the combined Chinese medicine into the extraction correlation coefficient calculation strategy corresponding to the comprehensive derived characteristic factors, and calculating and obtaining the extraction correlation coefficient corresponding to the comprehensive derived characteristic factors, the extraction correlation coefficient γ corresponding to the comprehensive derived characteristic factors φ The specific calculation strategy is:

[0130] in, They are respectively the set Φ of the comprehensive derived characteristic factors of the combined medicinal materials and the mean of the data in the effective amount set W′ of the predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of the combined Chinese medicine changing with time.

[0131] The Chinese medicine matching module to be extracted is used to intelligently match the proportion of medicinal material components in the combined medicinal materials according to user needs and the Chinese medicine characteristic model.

[0132] The microwave-assisted extraction monitoring module is used to monitor the extraction efficiency of the effective components in the extraction process in real time and to execute the corresponding extraction parameter feedback adjustment strategy.

[0133] The microwave-assisted extraction monitoring module includes an extraction efficiency calculation unit, an extraction efficiency monitoring unit and a feedback adjustment unit;

[0134] The calculation strategy of the extraction efficiency η of the combined medicinal material effective components in the extraction efficiency calculation unit is specifically as follows:

[0135]

[0136] Among them, n t The concentration of the active ingredient extracted from the combined medicinal materials being extracted; mb is the target value of the active ingredient in the combined medicinal material being extracted;

[0137] Extract the correlation coefficient for the whole,

[0138] Among them, ε1, ε2, and ε3 are the influencing proportional factors of the extracted correlation coefficients.

[0139] The monitoring strategy of the extraction efficiency monitoring unit includes:

[0140] S51: monitoring the effective ingredient concentration difference Δnd, presetting the minimum effective threshold of the effective ingredient, and when the effective ingredient concentration difference Δnd is greater than the minimum effective threshold, extending the microwave-assisted extraction time and continuing monitoring, wherein:

[0141] S52: synchronously calculating the difference between the extraction efficiency η of the combined medicinal material effective components and the target extraction efficiency η0 as Δη, and presetting the maximum tolerance difference of the extraction efficiency;

[0142] When the difference Δη is greater than the maximum tolerable difference in extraction efficiency, the original microwave-assisted extraction power is increased first, and the extraction temperature of the microwave-assisted extraction container is monitored simultaneously. When the average temperature during the monitoring period exceeds the maximum pyrolysis temperature of the combined medicinal materials, the power is immediately reduced to the original microwave-assisted extraction power, and the staff is notified to manually adjust the microwave-assisted power.

[0143] Embodiment 2:

[0144] This embodiment provides an electronic device, including: a processor and a memory, wherein the memory stores a computer program that can be called by the processor;

[0145] The processor is used to run the microwave-assisted extraction system of effective components of traditional Chinese medicine for treating myopia by calling the computer program stored in the memory.

[0146] The electronic device may have relatively large differences due to different configurations or performances, and may include one or more processors (Central Processing Units, CPU) and one or more memories, wherein at least one computer program is stored in the memory, and the computer program is loaded and executed by the processor to implement the microwave-assisted extraction system of effective components of traditional Chinese medicine for treating myopia provided in the above embodiment. The electronic device may also include other components for realizing the functions of the device, for example, the electronic device may also have components such as a wired or wireless network interface and an input and output interface, so as to input and output data. This embodiment will not be described in detail here.

[0147] Embodiment three:

[0148] This embodiment provides a computer-readable storage medium having a rewritable computer program stored thereon;

[0149] When the computer program is run on a computer device, the computer device is enabled to run a microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia.

[0150] For example, the computer readable storage medium can be a read-only memory (ROM), a random access memory (RAM), a compact disc (CD-ROM), a magnetic tape, a floppy disk, and an optical data storage device, etc.

[0151] It should be understood that in the various embodiments of the present application, the size of the serial numbers of the above-mentioned processes does not mean the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.

[0152] It should be understood that determining B based on A does not mean determining B only based on A. B can also be determined based on A and / or other information.

[0153] The above embodiments can be implemented in whole or in part by software, hardware, firmware or any other combination. When implemented by software, the above embodiments can be implemented in whole or in part in the form of a computer program product. The computer program product includes one or more computer instructions or computer programs. When a computer instruction or computer program is loaded or executed on a computer, a process or function according to an embodiment of the present invention is generated in whole or in part. The computer can be a general-purpose computer, a special-purpose computer, a computer network, or other programmable device. Computer instructions can be stored in a computer-readable storage medium, or transmitted from one computer-readable storage medium to another computer-readable storage medium. For example, computer instructions can be transmitted from one website site, computer, server or data center to another website site, computer, server or data center through a wired network or / and a wireless network. The computer-readable storage medium can be any available medium that a computer can access or a data storage device such as a server or data center that contains one or more available media sets. The available medium can be a magnetic medium (e.g., a floppy disk, a hard disk, a tape), an optical medium (e.g., a DVD), or a semiconductor medium. The semiconductor medium can be a solid-state hard disk.

[0154] Those skilled in the art will appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed in the present invention can be implemented in electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Professional and technical personnel can use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of the present invention.

[0155] Those skilled in the art can clearly understand that, for the convenience and brevity of description, the specific working processes of the systems, devices and units described above can refer to the corresponding processes in the aforementioned method embodiments and will not be repeated here.

[0156] In the several embodiments provided by the present invention, it should be understood that the disclosed systems, devices and methods can be implemented in other ways. For example, the device embodiments described above are only schematic, for example, the division of units is only one, and there may be other division methods in actual implementation, such as multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point is that the mutual coupling or direct coupling or communication connection shown or discussed can be through some interfaces, indirect coupling or communication connection of devices or units, which can be electrical, mechanical or other forms.

[0157] The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0158] In addition, each functional unit in each embodiment of the present invention may be integrated into one processing unit, or each unit may exist physically separately, or two or more units may be integrated into one unit.

[0159] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0160] In summary, compared with the prior art, the technical effects of the present invention are as follows:

[0161] 1. The traditional Chinese medicine data acquisition module in the present invention collects comprehensive data through the physical property acquisition unit and the microwave response characteristic acquisition unit. The system can obtain more comprehensive medicinal material data, including cell wall thickness, porosity, medicinal material surface area, etc., and construct a traditional Chinese medicine characteristic model through the calculation of derived characteristic factors and the establishment of characteristic vector sets, providing a basis for subsequent extraction efficiency optimization.

[0162] 2. The present invention accurately quantifies the relationship between medicinal material characteristics and extraction effect. By extracting the changes in extraction efficiency under different parameters, the influence of different parameters on microwave-assisted extraction efficiency is quantified, solving the problem that the traditional method lacks accurate quantification means, resulting in unstable extraction effect or failure to fully utilize the effective ingredients of medicinal materials.

[0163] 3. The extraction efficiency monitoring unit in the present invention ensures the high efficiency and stability of the extraction process through precise efficiency calculation and real-time data monitoring. The automatic adjustment function effectively avoids the problems of overheating or inefficient extraction, thereby improving the overall extraction effect and the operational reliability of the system.

[0164] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A microwave-assisted extraction system for effective ingredients of traditional Chinese medicine for treating myopia, characterized in that: The system includes the following modules: Traditional Chinese medicine data collection module, traditional Chinese medicine characteristic model construction module, extraction correlation coefficient calculation module, traditional Chinese medicine matching module to be extracted and microwave-assisted extraction monitoring module; The traditional Chinese medicine data collection module is used to collect basic medicinal material data related to the selected traditional Chinese medicine; The Chinese medicine characteristic model building module is used to build a Chinese medicine characteristic model, identify the contribution of the effective ingredients in the medicinal materials to the treatment of myopia, and extract the medicinal material characteristics of each medicinal material with contributing ingredients in the combined medicinal materials; The extraction correlation coefficient calculation module is used to quantify the relationship between the medicinal material characteristics of each medicinal material in the combined Chinese medicine and its extraction effect; The Chinese medicine matching module to be extracted is used to intelligently match the proportion of medicinal ingredients in the combined medicinal materials according to user needs and the Chinese medicine characteristic model; The microwave-assisted extraction monitoring module is used to monitor the extraction efficiency of the effective components in the extraction process in real time and to execute the corresponding extraction parameter feedback adjustment strategy.

2. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 1, characterized in that: The traditional Chinese medicine data acquisition module includes: a physical property acquisition unit and a microwave response characteristic acquisition unit; the physical property acquisition unit is used to obtain cell wall thickness data, medicinal material porosity data, medicinal material surface area data and medicinal material surface scanning image data in traditional Chinese medicine; the microwave response characteristic acquisition unit is used to collect the medicinal material ratio of each medicinal material in the historical extraction combination medicinal material, the microwave-assisted extraction parameters in the historical extraction process of the combination medicinal material and the concentration of each effective ingredient obtained by the combination medicinal material extraction.

3. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 2, characterized in that: The Chinese medicine characteristic model construction module is used to run the following specific steps: S21: extracting the basic data of medicinal materials collected in the traditional Chinese medicine data collection module, and calculating the derived characteristic factors of the medicinal materials, wherein the derived characteristic factors include: a derived characteristic factor of cell wall thickness, a derived characteristic factor of porosity, and a derived characteristic factor of medicinal material surface area; Among them, the cell wall thickness derived characteristic factor F cell The calculation strategy is: d is the thickness of the medicinal material cell wall, d0 is the target thickness of the medicinal material cell wall, k is the influence of the cell wall thickness on the medicinal material extraction efficiency, and c represents the pretreatment factor; Porosity-derived characteristic factor F po The calculation strategy is: K is the surface porosity of the medicinal material; ρ is the density of the medicinal material; p is the particle size of the medicinal material; Surface area-derived characteristic factor F sa The calculation strategy is: N is the total number of pixels in the scanned image data of the medicinal material surface; S is the surface area of ​​the medicinal material, XS n Indicates the pixel value of the nth pixel in the scanned image data of the medicinal material surface, XS max , XS min They are the maximum pixel value point and the minimum pixel value point in the scanned image data of the medicinal material surface respectively; S22: extracting the medicinal material ratio of each medicinal material in the historical extraction of the combined medicinal materials, the microwave-assisted extraction parameters in the historical extraction process of the combined medicinal materials, and the concentrations of each effective ingredient obtained by the combined medicinal materials extraction, and combining the data to form a historical extraction feature vector set of the combined medicinal materials, and at the same time dividing the historical extraction feature vector set of the combined medicinal materials into a training set and a test set in a ratio of 9:

1.

4. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 3, characterized in that: The operation strategy of the traditional Chinese medicine characteristic model construction module also includes: S23: combining the derived characteristic factors of a single type of medicinal material into a characteristic vector form, and obtaining a basic characteristic vector set of each type of medicinal material in the combined medicinal material; S24: constructing a Chinese medicine feature model, wherein the Chinese medicine feature model comprises: an input layer, a hidden layer and an output layer; the input of the Chinese medicine feature model is a basic feature vector set of each type of medicinal material in the combined medicinal material and a historically extracted feature vector set of the combined medicinal material; the hidden layer comprises 8 10×10 convolution kernels; the output of the output layer is a predicted value of the concentration of each active ingredient extracted from the combined medicinal material; S25: standardizing the basic feature vector set of each type of medicinal material in the combined medicinal material and the historically extracted feature vector set of the combined medicinal material, and extracting medicinal material features using a traditional Chinese medicine feature model; S26: Use the neurons in the hidden layer to perform convolution calculations, specifically: in, is the output of the jth neuron in the lth hidden layer; is the activation value of the i-th neuron in the l-1-th hidden layer; is the bias term of the jth neuron in the lth hidden layer; is the contribution weight from the i-th neuron in the l-1th hidden layer to the j-th neuron in the l-th hidden layer; m is the total number of neurons in the hidden layer; S27: Testing the traditional Chinese medicine feature model using a test set, and stopping the training when the sum of the prediction accuracies reaches convergence.

5. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 4, characterized in that: The operation strategy of the extraction correlation coefficient calculation module includes: S31: extracting the parent curve of the predicted value of each effective component concentration versus extraction time, and the parent curve of the microwave-assisted extraction power and microwave-assisted extraction temperature versus extraction time; S32: intercepting multiple combined Chinese medicine microwave-assisted extraction processes whose predicted values ​​of the concentration of each active ingredient differ by no more than 5%, and synchronously extracting sub-curves of predicted values ​​of the concentration of each active ingredient versus extraction time, microwave-assisted extraction power, and microwave-assisted extraction temperature versus extraction time corresponding to the multiple combined Chinese medicine microwave-assisted extraction processes obtained; S33: separating the sub-curves of microwave-assisted extraction power and microwave-assisted extraction temperature versus extraction time in the microwave-assisted extraction process of the combined traditional Chinese medicine, taking the microwave-assisted extraction process of the combined traditional Chinese medicine corresponding to the microwave-assisted extraction power to form an interference set of microwave-assisted extraction power, taking the microwave-assisted extraction power adjustment amount in the interference set of microwave-assisted extraction power and the change amount of the predicted value of each active ingredient concentration in the microwave-assisted extraction process of the combined traditional Chinese medicine versus extraction time; Among them, the set of microwave-assisted extraction power adjustment amounts is: Where V is the total number of combined Chinese medicines in set A; The superscript g represents the microwave-assisted extraction power corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscript represents the microwave-assisted extraction process of the vth combination of traditional Chinese medicines. That is, the microwave-assisted extraction power of the vth combined traditional Chinese medicine microwave-assisted extraction process; Among them, in the interference set of microwave-assisted extraction power, the effective amount set of the predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the vth combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the vth combination of traditional Chinese medicines; S34: introducing the set A of microwave-assisted extraction power adjustment amounts and the effective amount set A′ of predicted values ​​of concentrations of each effective component corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine over time into the extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction power, and calculating and obtaining the extraction correlation coefficient corresponding to the microwave-assisted extraction power. The extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction power is specifically as follows: in, They are respectively the set A of microwave-assisted extraction power adjustment amounts and the mean data of the effective amount set A′ of predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time;.

6. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 5, characterized in that: The operation strategy of the extraction correlation coefficient calculation module also includes: S35: The curve of microwave-assisted extraction temperature and extraction time obtained during microwave-assisted extraction of combined Chinese medicine; S36: intercepting the microwave-assisted extraction process of the combined traditional Chinese medicine with the same microwave-assisted extraction power, setting it as the interference set of microwave-assisted extraction temperature, taking the adjustment amount of the microwave-assisted extraction temperature in the interference set of microwave-assisted extraction temperature and the change amount of the predicted value of each effective component concentration in the microwave-assisted extraction process of the combined traditional Chinese medicine with the extraction time; Among them, the set of microwave-assisted extraction temperature adjustment amounts is: Where U is the total number of combined Chinese medicines in set B; The superscript Te of represents the microwave-assisted extraction temperature corresponding to the microwave-assisted extraction process of this combined Chinese medicine, and the subscript Te represents the microwave-assisted extraction process of the u-th combined Chinese medicine. That is, the microwave-assisted extraction temperature of the u-th combined traditional Chinese medicine microwave-assisted extraction process; Among them, in the interference set of microwave-assisted extraction temperature, the effective amount set of the predicted values ​​of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the u-th combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the u-th combination of traditional Chinese medicines; S37: The set B of microwave-assisted extraction temperature adjustment amounts and the effective amount set B′ of predicted values ​​of concentrations of each effective component corresponding to the microwave-assisted extraction process of the combined traditional Chinese medicine that change with time are introduced into the extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction temperature, and the extraction correlation coefficient corresponding to the microwave-assisted extraction temperature is calculated and obtained. The extraction correlation coefficient calculation strategy corresponding to the microwave-assisted extraction temperature is specifically: in, They are respectively the set B of microwave-assisted extraction temperature adjustment values ​​and the mean data of the effective amount set B′ of predicted values ​​of each effective component concentration corresponding to the microwave-assisted extraction process of combined traditional Chinese medicine changing with time.

7. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 6, characterized in that: The operation strategy of the extraction correlation coefficient calculation module also includes: S38: Extract the derived characteristic factors of the medicinal materials and calculate the comprehensive derived characteristic factor φ of the combined medicinal materials. The calculation formula is: Where x is a subscript, indicating the xth type of medicinal material in the combined medicinal material, X is the total number of medicinal material categories in the combined medicinal material; α1, α2, and α3 are the comprehensive proportional coefficients of the derived characteristic factors of the medicinal materials respectively; F cell,x ,F po,x ,F sa,x They represent the cell wall thickness-derived characteristic factor, porosity-derived characteristic factor and medicinal material surface area-derived characteristic factor of the x-th type of medicinal material, respectively; S39: microwave-assisted extraction process of combined traditional Chinese medicine with the same microwave-assisted extraction temperature and microwave-assisted extraction power; Taking the combined traditional Chinese medicine microwave-assisted extraction process corresponding to the comprehensive derived characteristic factors of the combined medicinal materials, an interference set of the comprehensive derived characteristic factors of the combined medicinal materials is formed; Take the comprehensive derived characteristic factors in the interference set of the comprehensive derived characteristic factors of the combined medicinal materials and the changes of the predicted values ​​of the concentrations of each effective component in the microwave-assisted extraction process of the combined Chinese medicine with the extraction time; Among them, the set of comprehensive derived characteristic factors is: Where E is the total number of combined Chinese medicines in the set Φ, The superscript φ represents the comprehensive derivative characteristic factor corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscript φ represents the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines. That is, the comprehensive derived characteristic factor of the microwave-assisted extraction process of the e-th combined traditional Chinese medicine; Among them, in the interference set of the comprehensive derived characteristic factors of the combined medicinal materials, the effective amount set of the predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of the combined Chinese medicine changing with time is: in The superscripts represent the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of this combination of traditional Chinese medicines, and the subscripts represent the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines. is the effective amount of the predicted value of the concentration of each active ingredient corresponding to the microwave-assisted extraction process of the e-th combination of traditional Chinese medicines; S310: introducing the set of comprehensive derived characteristic factors Φ of the combined medicinal materials and the effective amount set W′ of the predicted values ​​of the concentrations of the active ingredients corresponding to the microwave-assisted extraction process of the combined Chinese medicine into the extraction correlation coefficient calculation strategy corresponding to the comprehensive derived characteristic factors, and calculating and obtaining the extraction correlation coefficient corresponding to the comprehensive derived characteristic factors, the extraction correlation coefficient γ corresponding to the comprehensive derived characteristic factors φ The specific calculation strategy is: in, They are respectively the set Φ of the comprehensive derived characteristic factors of the combined medicinal materials and the mean of the data in the effective amount set W′ of the predicted values ​​of the concentrations of each active ingredient corresponding to the microwave-assisted extraction process of the combined Chinese medicine changing with time.

8. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 7, characterized in that: The microwave-assisted extraction monitoring module includes an extraction efficiency calculation unit, an extraction efficiency monitoring unit and a feedback adjustment unit; The calculation strategy of the extraction efficiency η of the combined medicinal material effective components in the extraction efficiency calculation unit is specifically as follows: Among them, n t The concentration of the active ingredient extracted from the combined medicinal materials being extracted; mb is the target value of the active ingredient in the combined medicinal material being extracted; Extract the correlation coefficient for the whole, Among them, ε1, ε2, and ε3 are the influencing proportional factors of the extracted correlation coefficients.

9. The microwave-assisted extraction system for effective components of traditional Chinese medicine for treating myopia according to claim 8, characterized in that: The monitoring strategy of the extraction efficiency monitoring unit includes: S51: monitoring the effective ingredient concentration difference Δnd, presetting the minimum effective threshold of the effective ingredient, and when the effective ingredient concentration difference Δnd is greater than the minimum effective threshold, extending the microwave-assisted extraction time and continuing monitoring, wherein: S52: synchronously calculating the difference between the extraction efficiency η of the combined medicinal material effective components and the target extraction efficiency η0 as Δη, and presetting the maximum tolerance difference of the extraction efficiency; When the difference Δη is greater than the maximum tolerable difference in extraction efficiency, the original microwave-assisted extraction power is increased first, and the extraction temperature of the microwave-assisted extraction container is monitored simultaneously. When the temperature average during the monitoring period exceeds the maximum pyrolysis temperature of the combined medicinal materials, the power is immediately reduced to the original microwave-assisted extraction power, and the microwave-assisted power is manually adjusted.

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