Efficient burn medicine as well as preparation method and application thereof

Abstract

The invention belongs to the technical field of burn medicines, and particularly relates to an efficient burn medicine as well as a preparation method and application thereof. Comprising the following raw materials in parts by weight: 1 part of polygonum cuspidatum, 1 part of rheum officinale, 1 part of sanguisorba officinalis, 1 part of borneol, 1 part of humifuse euphorbia herb, 1 part of rhizoma bletillae, 1 part of golden cypress, 1 part of lithospermum, 1 part of honeysuckle, 1 part of radix sophorae flavescentis, 1 part of frankincense, 1 part of myrrh, 1 part of angelica sinensis, 1 part of astragalus membranaceus, 1 part of cortex moutan, 1 part of radix rehmanniae recen and 1000 parts of water. And cooling to room temperature to form liquid medicine for later use. The prepared efficient burn medicine is a decoction. The burn medicine prepared by the invention can better solve the problems of microcirculation obstacle, tissue hypoxia ischemia and the like in treatment of I-degree, shallow II-degree, deep II-degree and III-degree burns, revive and regenerate stasis regions and hyperemia regions, reduce the area of coagulation necrosis regions and promote regeneration of wound skin musculature bones.

Description

Technical Field

[0001] The invention belongs to the technical field of burn medicines, and in particular relates to a highly effective burn medicine, a preparation method and uses thereof. Background Art

[0002] Burns are an acute trauma caused by heat (water, soup, oil and other hot liquids, flames, hot metals), high-voltage electric arcs, strong acids and alkalis, gamma rays, etc. acting on the human body. They are often localized and spread to the whole body, and serious systemic complications may occur. This disease is also called burns in Western medicine. Burns and accidental disasters are common in daily life. In ancient times, most people were burned by flames, boiling water, and hot oil, so they are also called water scalds, soup burns, fire sores, soup sores, and fire sores. In modern times, chemical burns, radioactive burns, and electric shock injuries have also appeared. Its clinical characteristics are that the wound surface is mainly manifested by erythema, edema, heat pain, suppuration, exudation, and scabs. In severe cases, there is high fever, irritability, thirst and drinking, oliguria or anuria, and even pale complexion, shallow and rapid breathing, coma and delirium. If not treated in time or the treatment method is inappropriate, it may threaten life.

[0003] The so-called topical drugs for burns in clinical medicine refer to topical drugs that are left on the wound surface during the treatment of burns and play a stable role, including iodine, sulfonamide antibiotics, benzalkonium bromide, mupirocin, polymyxin B sulfate, recombinant human epidermal growth factor, etc. Its main function is to control infection, avoid the deterioration of trauma, and accelerate the shedding of necrotic tissue, reconstruction of fibrous tissue, and regeneration of epidermis and other tissues.

[0004] However, the efficacy of current topical medications is limited. They can only be used to treat first-degree and shallow second-degree burns and to remove scabs from large-scale burns. It is very difficult to treat large-scale or deep second-degree burns. The treatment of deep second-degree and third-degree burns still needs to be combined with auxiliary means such as skin grafting surgery, mist wet compresses, and far-infrared irradiation. Summary of the invention

[0005] The purpose of the present invention is to provide a highly effective burn medicine, a preparation method and a use thereof. The prepared burn medicine can better solve the problems of microcirculation disorders, tissue hypoxia and ischemia in the treatment of first-degree, superficial second-degree, deep second-degree and third-degree burns, revive and regenerate stasis areas and congestion areas, reduce the area of ​​coagulation necrosis areas, and promote the regeneration of wound skin, muscles and bones.

[0006] The technical solution adopted by the present invention is as follows:

[0007] A highly effective burn medicine, preparation method and use, comprising the following raw materials in parts by weight:

[0008] 0.8-1.5 parts of Polygonum cuspidatum, 0.8-1.5 parts of Rhubarb, 0.8-1.5 parts of Sanguisorba officinalis, 0.8-1.5 parts of Borneolum, 0.8-1.5 parts of Euphorbia trichosanthis, 0.8-1.5 parts of Bletilla striata, 0.8-1.5 parts of Phellodendron chinense, 0.8-1.5 parts of Lithospermum officinale, 0.8-1.5 parts of Honeysuckle, 0.8-1.5 parts of Sophora flavescens, 0.8-1.5 parts of frankincense, 0.8-1.5 parts of Myrrh, 0.8-1.5 parts of Angelica sinensis, 0.8-1.5 parts of Astragalus, 0.8-1.5 parts of Moutan bark, 0.8-1.5 parts of Rehmannia root, and 800-1500 parts of water.

[0009] Further, the following raw materials are included in parts by weight:

[0010] 1 part of Polygonum cuspidatum, 1 part of Rhubarb, 1 part of Sanguisorba officinalis, 1 part of Borneolum, 1 part of Herba Euphorbiae Ichthyophthirius, 1 part of Bletilla striata, 1 part of Phellodendron chinense, 1 part of Lithospermum officinale, 1 part of Honeysuckle, 1 part of Sophora flavescens, 1 part of Frankincense, 1 part of Myrrh, 1 part of Angelica sinensis, 1 part of Astragalus, 1 part of Moutan Cortex, 1 part of Rehmannia glutinosa, and 1000 parts of water.

[0011] A method for preparing a highly effective burn medicine comprises the following steps:

[0012] Bring to a boil over high heat and start counting the time, then turn down the heat and simmer for another 30 minutes over low heat. Stir evenly and let it sit for 1 hour before cooling to room temperature to form a syrup for later use.

[0013] The technical effects achieved by the present invention are:

[0014] The invention discloses a highly effective burn medicine, a preparation method and a use thereof. The prepared burn medicine is applied by a wet compress soaking method. Under the guidance of the theoretical system of traditional Chinese medicine, the prepared burn medicine achieves the expected purpose through the combination of "monarch, minister, assistant and messenger". In the treatment of first degree, shallow second degree, deep second degree and third degree burns, the problems of microcirculation disorder, tissue hypoxia and ischemia can be better solved, and the stasis area and congestion area can be revived and regenerated, the area of ​​the coagulation necrosis area can be reduced, and the regeneration of the skin, muscles and bones of the wound surface can be promoted, thereby restoring the wound surface to the pre-disease state, "hair grows, and the patient is as beautiful as before". DETAILED DESCRIPTION

[0015] In order to make the purpose and advantages of the present invention more clearly understood, the present invention is specifically described below in conjunction with embodiments. It should be understood that the following text is only used to describe one or several specific embodiments of the present invention, and does not strictly limit the scope of protection of the specific claims of the present invention.

[0016] A highly effective burn medicine, comprising at least the following raw materials:

[0017] Polygonum cuspidatum (root and stem of Polygonum cuspidatum, Polygonaceae), Rheum palmatum (root and stem of Rheum palmatum, Polygonaceae), Sanguisorba officinalis (root of Sanguisorba officinalis, Rosaceae), Borneol (resin of Dipterocarpus rotundus), Euphorbia cerifera (dried whole herb of Euphorbia cerifera, Euphorbia cerifera), Bletilla striata (dried tuber of Bletilla striata, Orchidaceae), Phellodendron amurense (dried bark of Phellodendron rotundus, Rutaceae), Lithospermum officinale (dried root of Lithospermum xinjiang, Boraginaceae), Honeysuckle (dried flower bud of Lonicera japonica, Caprifoliaceae), Sophora flavescens (dried root of Sophora flavescens, Leguminosae), Frankincense (resin exuded from the bark of Frankincense, Oleaceae), Myrrh (dried resin of the Oleaceae plant, Angelica sinensis (dried root of the Apiaceae plant, Angelica sinensis), Astragalus (dried root of the Leguminosae plant, Astragalus mongolica), Moutan bark (dried root bark of the Ranunculaceae plant, Paeonia suffruticosa), Rehmannia glutinosa (tuber of the Scrophulariaceae plant, Rehmannia glutinosa), Houttuynia cordata (dried aerial part of the Saururaceae plant, Houttuynia cordata), Patrinia salsa (dried whole herb of Patrinia salsa of the Patrinia salsa), Forsythia suspensa (dried fruit of the Forsythia suspensa of the Oleaceae plant), Panax notoginseng (dried root and rhizome of Panax notoginseng of the Araliaceae plant), Acorus calamus (dried rhizome of Acorus calamus of the Araceae plant).

[0018] Among them, the functions of Polygonum cuspidatum are clearing away heat and detoxifying; helping to reduce inflammatory response and promote wound healing.

[0019] Among them, the function of rhubarb is to clear away heat, purge fire and detoxify; it has a certain effect in clearing away heat toxins after burns.

[0020] Among them, the functions of Sanguisorba officinalis are cooling blood and stopping bleeding, detoxifying and healing sores; when used on burn wounds, it can stop bleeding and promote wound contraction and healing.

[0021] Among them, the functions of borneol are to open the orifices and refresh the mind, clear away heat and relieve pain; it can relieve burn pain and has a certain antibacterial effect.

[0022] Among them, the functions of ground ivy are clearing away heat and detoxifying, cooling blood and stopping bleeding, promoting dampness and relieving jaundice; it helps to clear heat and toxins from burns and prevent infection.

[0023] Among them, the functions of Bletilla striata are astringent hemostasis, swelling reduction and tissue regeneration; it has a good effect on hemostasis and tissue regeneration promotion on burn wounds.

[0024] Among them, the functions of Huangbai are clearing away heat and dampness, purging fire and detoxifying, and eliminating bone steaming; it can clear away heat and dampness and prevent infection of burn wounds.

[0025] Among them, the functions of Lithospermum officinale are clearing away heat and cooling blood, promoting blood circulation and detoxifying, and clearing rashes and removing spots; it has the effect of cooling blood and detoxifying, and is beneficial to the recovery of wounds after burns.

[0026] Among them, the functions of honeysuckle are clearing away heat, detoxifying, and dispersing wind-heat; it has a good effect in clearing away heat toxins caused by burns.

[0027] Among them, the functions of Sophora flavescens are clearing away heat and dampness, killing insects, and promoting diuresis; it can help prevent wound infection.

[0028] Among them, the functions of frankincense are to promote blood circulation, relieve pain, reduce swelling and promote tissue regeneration; promote blood circulation in the burn area and accelerate wound healing.

[0029] Among them, the functions of myrrh are to disperse blood stasis, relieve pain, reduce swelling and promote tissue regeneration; it works synergistically with frankincense to help burn wounds recover.

[0030] Among them, the functions of angelica are to nourish blood and promote blood circulation, regulate menstruation and relieve pain, and moisten the intestines and promote bowel movements; it can improve local blood circulation in burns and promote tissue repair.

[0031] Among them, the functions of Astragalus are to tonify Qi and raise Yang, consolidate the exterior and stop sweating, promote diuresis and reduce swelling, promote body fluid and nourish blood, relieve stagnation and numbness, expel toxins and discharge pus, and heal sores and promote tissue regeneration; it enhances the body's immunity and promotes wound healing.

[0032] Among them, the functions of Cortex Moutan are clearing away heat, cooling blood, promoting blood circulation and removing blood stasis; it helps to cool blood and promote blood circulation after burns.

[0033] Among them, the functions of raw Rehmannia are clearing away heat and cooling blood, nourishing yin and promoting body fluid; it can clear away heat and cool blood, creating a good environment for the recovery of burn wounds.

[0034] Among them, the functions of Houttuynia cordata are clearing away heat and detoxifying, eliminating carbuncle and discharging pus, and promoting diuresis and relieving stranguria; it enhances the effect of clearing heat and detoxifying, and prevents the infection of wound from worsening.

[0035] Among them, the functions of Patrinia salsa are clearing away heat and detoxifying, eliminating carbuncle and discharging pus, removing blood stasis and relieving pain; assisting in clearing heat and toxins and promoting wound recovery.

[0036] Among them, the functions of Forsythia suspensa are clearing away heat and detoxifying, reducing swelling and dispersing nodules, and evacuating wind-heat; it has a good effect in clearing away heat toxins caused by burns.

[0037] Among them, the functions of Panax notoginseng are to disperse blood stasis and stop bleeding, reduce swelling and relieve pain; it can promote blood circulation and remove blood stasis, prevent blood stasis in burns, and promote wound healing.

[0038] Among them, the functions of calamus are to open the mind and dissipate phlegm, wake up the mind and improve intelligence, and remove dampness and stimulate appetite. In the treatment of burns, it may play an auxiliary role in removing dampness and promoting the circulation of qi and blood.

[0039] Embodiment 1:

[0040] A highly effective burn medicine comprising the following raw materials in parts by weight:

[0041] 0.8-1.5 parts of Polygonum cuspidatum, 0.8-1.5 parts of Rhubarb, 0.8-1.5 parts of Sanguisorba officinalis, 0.8-1.5 parts of Borneolum, 0.8-1.5 parts of Euphorbia trichosanthis, 0.8-1.5 parts of Bletilla striata, 0.8-1.5 parts of Phellodendron chinense, 0.8-1.5 parts of Lithospermum officinale, 0.8-1.5 parts of Honeysuckle, 0.8-1.5 parts of Sophora flavescens, 0.8-1.5 parts of frankincense, 0.8-1.5 parts of Myrrh, 0.8-1.5 parts of Angelica sinensis, 0.8-1.5 parts of Astragalus, 0.8-1.5 parts of Moutan bark, 0.8-1.5 parts of Rehmannia root, and 800-1500 parts of water.

[0042] The above 21 Chinese herbal medicines are preferably prepared in equal proportions, specifically:

[0043] 1 part of Polygonum cuspidatum, 1 part of Rhubarb, 1 part of Sanguisorba officinalis, 1 part of Borneolum, 1 part of Herba Euphorbiae Ichthyophthirius, 1 part of Bletilla striata, 1 part of Phellodendron chinense, 1 part of Lithospermum officinale, 1 part of Honeysuckle, 1 part of Sophora flavescens, 1 part of Frankincense, 1 part of Myrrh, 1 part of Angelica sinensis, 1 part of Astragalus, 1 part of Moutan Cortex, 1 part of Rehmannia glutinosa, and 1000 parts of water.

[0044] Embodiment 2:

[0045] This embodiment discloses a method for preparing a highly effective burn medicine based on embodiment 1, comprising the following steps:

[0046] Bring to a boil over high heat (flame temperature 300℃ and above), start timing, turn down the heat, and simmer over low heat (flame temperature between 100℃ and 200℃) for another 30 minutes, stir evenly, leave it for 1 hour, and then cool to room temperature (flame temperature between 20℃ and 25℃) to form a potion for use.

[0047] Embodiment 3:

[0048] This embodiment discloses another method for preparing a highly effective burn medicine based on the embodiment 1, comprising the following steps:

[0049] S1. Pretreatment: All 21 Chinese herbal medicines (Polygonum cuspidatum, Rhubarb, Sanguisorba officinalis, Borneolum, Herba Euphorbiae, Bletilla striatae, Cortex Phellodendri, Lithospermum officinale, Flos Lonicerae, Sophorae Flavescentis, Olibanum, Myrrha, Angelicae Sinensis, Astragalus, Cortex Moutan, Radix Rehmanniae) were accurately weighed in equal proportions, mixed and put into a Chinese herbal medicine decoction bag. This can facilitate subsequent operations and avoid excessive herbal residues remaining in the liquid medicine.

[0050] S2. High-fire shock: Put the decoction bag containing the herbs into the pot and add 1000mL of pure water. First, use high fire (flame temperature 300℃ and above) to quickly boil the water until the water temperature reaches 100℃. Start timing. This step lasts for 5 minutes. The strong steam power and high temperature generated at this time can quickly activate the active ingredients in the herbs, making them easier to release.

[0051] S3, frequency conversion, alternating between medium and strong: After 5 minutes, adjust the fire to medium (flame temperature between 200℃ and 300℃) and keep it for 3 minutes. This medium fire state can keep the temperature in the pot relatively stable, allowing the herbs to further release their ingredients during the continuous heating process, while avoiding excessive boiling that may cause the liquid to overflow or the destruction of the active ingredients. Then, reduce the fire to a slow fire (flame temperature between 100℃ and 200℃) and boil for 20 minutes.

[0052] Slow frying helps the various ingredients in the herbs to fully blend and transform, thereby improving the efficacy. During the slow frying process, stir slowly and evenly every 5 minutes to allow the herbs to fully contact with water, ensure that all parts are heated evenly, and release the ingredients more completely.

[0053] S4. Ultrasonic assisted infusion: After simmering for 20 minutes, turn off the heat, but do not remove the decoction bag immediately. Use the residual heat in the pot to perform ultrasonic assisted infusion on the medicinal solution. Place a small ultrasonic generator in the pot (make sure it is waterproof and will not contaminate the medicinal solution), turn on the ultrasonic function, and perform ultrasonic treatment at low power (10W~30W) for 10 minutes. Ultrasonic vibration can break the herbal cell structure at the microscopic level, further promoting the release and dissolution of active ingredients into the medicinal solution, thereby increasing the concentration and efficacy of the drug.

[0054] S5. Natural precipitation and cooling: After the ultrasonic treatment, take out the medicine liquid together with the decoction bag and place it in a well-ventilated place without direct sunlight. Let it settle naturally for 1 hour to form a medicine solution for use. During the precipitation process, the medicine liquid gradually cools to room temperature, and some fine impurities and sediments will settle to the bottom of the container.

[0055] Embodiment 4:

[0056] This embodiment discloses the use of the high-efficiency burn medicine on the basis of the above-mentioned embodiment. Specifically, the high-efficiency burn medicine is used to treat burn wounds and can be used to prepare medicine for treating burn wounds.

[0057] The specific treatment method is to soak cotton wool in medicine and apply it to the burn wound. The burn wound can also be directly soaked in the medicine to keep it moist and watery at all times. Soaking the wound directly in the medicine will have a faster and better effect.

[0058] The watery state refers to the obvious moistness of the wound surface, with a thin layer of liquid covering the surface, similar to the gloss formed by water on the surface. This layer of liquid is usually a mixture of moisturizing ingredients provided by the moist dressing or medicine used in burn treatment and tissue fluid exuded from the wound surface itself. This moist appearance makes people intuitively feel that the wound surface is in a state rich in moisture.

[0059] On the other hand, from a functional point of view, "watery" means that the wound surface is in a microenvironment that is conducive to healing. This moist state can keep the cells on the wound surface in a relatively stable physiological state, providing suitable conditions for cell growth, proliferation and migration. At the same time, it helps prevent adverse consequences such as tissue dehydration, cell death and wound deepening caused by dry wound surface. In addition, this moist environment is conducive to promoting local blood circulation in the wound surface, bringing more nutrients and immune cells, and accelerating the repair process of the wound surface.

[0060] If there is no oil stain on the burn wound, wet compress or soak it directly, and there is no need to clean the wound. If there is dirt, just rinse it with medicine. If there is oil stain on the wound, the oil stain must be washed off. For example, use household detergents, dip cotton wool in detergent to wash off the oil stain from the wound. No further cleaning is needed. Directly wet compress the burn wound with cotton wool soaked in medicine, or soak the burn wound directly in medicine, which is faster and better. Repeat soaking or wet compressing until the burn wound "grows hair and is as beautiful as before".

[0061] The above-mentioned medicine solution does not require scab removal or removal of blister skin when treating burns. The blister skin formed by burns is essentially a protective membrane of the human body, which plays a role in protecting skin regeneration. Therefore, it is clinically found that "no scab removal and no blister skin removal" can lead to faster recovery and more perfect regenerated skin.

[0062] Embodiment 5:

[0063] This technical solution discloses the effect of the burn medicine in detail on the basis of the above-mentioned embodiment. The diagnostic criteria of this technical solution are as follows:

[0064] If there is a definite history of burns, the cause of injury and the burn environment should be understood during diagnosis, and the injury should be comprehensively judged based on the burn area, depth, location, age, cause, presence of complex injuries and underlying diseases.

[0065] The course of the disease is generally divided into three stages:

[0066] Early stage (shock stage): usually occurs within 2 days after burns, mainly caused by massive exudation of body fluids and severe pain. It manifests as systemic or local reactive edema, blisters, eschars and massive exudation of body fluids on the wound surface. The patient is restless, thirsty and likes to drink, short of breath and panting, oliguria or nausea and vomiting. In severe cases, the patient will have a pale face, cold limbs, dazed look, weak pulse or weak and rapid pulse, which are dangerous signs of evil being trapped inside and the body fading outside.

[0067] Middle stage (infection stage): After the burn, the heat and toxic evil are rampant, a large area of ​​wound infection is caused on the body surface, the whole body immunity is reduced, the toxicity cannot be discharged, but instead penetrates into the interior (bacterial invasion and infection), and attacks the internal organs.

[0068] The above symptoms usually occur in three periods: the first is the fluid reabsorption period 3-7 days after the burn, when the intercellular fluid returns to the blood vessels and the fire toxins are trapped (bacteria enter the blood circulation); the second is the eschar autolysis and scabbing period 15 to 30 days after the burn. The third is the recovery period 30 days after the burn.

[0069] Late stage (repair stage): The wound surface begins to heal gradually, and new epithelial tissue begins to grow. During this stage, the patient's systemic symptoms gradually ease, appetite increases, and physical strength gradually recovers.

[0070] The burn area was calculated according to the new nine-point method of China, please refer to Table 1 for details;

[0071] Table 1 China's new nine-point method for estimating burn area

[0072]

[0073] Regardless of gender, age or status, the area of ​​the palm with five fingers folded in parallel is approximately equal to 1% of the body surface area. If the doctor's palm area is similar to that of the patient, the doctor's palm can be used for estimation. This method can assist the nine-point method and is used to calculate the area of ​​small or scattered burns.

[0074] At present, there are many methods for clinically judging the depth of burns, and the most commonly used is the three-degree four-degree method. First degree, second degree (also divided into shallow second degree and deep second degree), and third degree. Among them, first degree and shallow second degree burns are called shallow burns, and they generally do not leave scars if treated in time; deep second degree and third degree burns are deep burns, which often leave scars.

[0075] First degree burns (erythematous burns): only the epidermis (stratum corneum) is damaged, the germinal layer is intact and has strong regeneration ability. The wound surface is erythematous.

[0076] Superficial second-degree burns (blister burns): damage to the epidermal germinal layer and dermal papillary layer. Local redness and swelling are obvious, and large thin-walled blisters are formed.

[0077] Deep second-degree burns (blister burns): Injury to the deep dermis of the skin, with varying depths and skin appendages remaining. There may be blisters, and the wound surface is slightly moist after the blister skin is removed, with red and white tissues arranged alternately, and the pain sensation is not sharp.

[0078] Third degree burns (eschar burns): burns of the entire skin layer, even reaching the subcutaneous tissue, muscles, and bones. There are no blisters on the blister surface, which is brown leather-like or charred. The pain disappears, and branch-like embolized blood vessels can be seen under the scab. Generally, skin grafting is required for healing, and scars are left after healing, often forming deformities, and even difficult to heal on their own.

[0079] The severity of burns should be judged based on the area, depth, location, age, cause, and the presence or absence of complex injuries and underlying diseases. The two most basic aspects are the burn area and depth. The larger and deeper the burn area, the more serious the injury. In order to have a basic assessment of the severity of burns and as a reference for designing diagnosis and treatment plans, the grading method in Table 2 is used.

[0080] Table 2 Burn injury classification

[0081]

[0082] In order to verify the effect of burn medicine, we admitted hundreds of patients with burns and scalds transferred from hospitals, most of whom had deep second-degree and third-degree wounds that required skin grafting. After treatment with my burn medicine, all of them have healed without leaving any scars.

[0083] At the same time, this technical solution counted 1,500 cases of burn patients of varying degrees treated from 2003 to 2023, and compared and analyzed their healing time and degree of repair with the healing time and degree of repair of commonly used drugs on the market, and obtained the following results:

[0084] Ⅰ degree Superficial II Deep II III degree Highly effective burn medicine 1-3 days 4-6 days 7-10 days 10-20 days Commonly used drugs on the market 3-5 days 10-12 days More than 20 days Difficult to heal

[0085] For burns and scalds of various degrees, the pain will be alleviated and eliminated after using the burn medicine in this technical solution for 5 minutes.

[0086] Many burn patients are very painful and afraid when they think of the nurses peeling off the gauze adhered to the wound surface when changing the dressing. The burn medicine of this technical solution is a decoction, which adopts wet compress immersion therapy. The dressing is changed twice a day for severe burns and once a day for moderate and mild burns. The operation is simple and convenient, which can minimize the pain of patients changing dressings and cleaning the wound surface.

[0087] For third-degree burns, just apply a wet compress of burn medicine. There is no need for surgical skin grafting, biotechnology or immunotherapy. The burn wound will naturally scab over, and skin and hair will grow, making it as beautiful as before. This is the core competitiveness of the burn medicine of this technical solution, and it is also a revolutionary innovation in topical medicines for treating burns and scalds. It is a function that existing burn medicines on the market do not have.

[0088] There are many treatment methods for burns in clinical practice. In essence, wet compress immersion therapy is an extension of moist therapy and is actually equivalent to moist therapy.

[0089] George Winter of the University of London proposed moist therapy during the experiment. The purpose of the experiment was to compare the effects of closed and exposed therapies on wound healing. George Winter first discovered that wound healing speed in a closed moist environment is 50% higher, and the probability of adverse reactions is lower than that of dry wounds exposed to the air. This theory has been confirmed by experts from all over the world in clinical practice, laying the foundation for the use of bioactive composite materials to treat wounds. Moist therapy helps stimulate immune cells, induces local macrophages, enhances their aggregation ability and hydrolysis activity, promotes macrophages to produce interleukins and lysosomal components, and improves the body's ability to resist infection, thereby promoting wound healing.

[0090] The subjects selected in this study were patients with first-degree, superficial second-degree, deep second-degree, third-degree, mild, moderate, and severe burns. The use of wet compress soaking (moist therapy) had a significant effect. The "burn medicine" used in this study is an aqueous solution, a brown liquid, which is an external medicine that imitates physiological burn wounds. Its main functions are: to absorb moisture and heal sores, to promote tissue regeneration and reduce swelling, and to remove toxins and rot. It can improve the metabolism of local tissues, promote the restoration of normal physiological functions in stagnant and congested areas, regenerate skin and muscles, and grow hair, making the skin as beautiful as before.

[0091] The pathological changes of local tissues of burns are divided into three annular areas according to the different levels of local injury, namely ① the central coagulation necrosis area, ② the peripheral blood stasis area, and ③ the peripheral congestion area. Among them, only part of the tissue is damaged in the blood stasis area, not completely necrotized. The main changes in the tissues of the congestion and stasis areas are the decrease in elasticity of capillaries and the increase in permeability; slow blood flow, prone to microvascular embolism; local tissue hypoxia, which then affects the whole body. Therefore, how to inhibit the pathological and physiological changes in the stasis and congestion areas, reduce their impact on the body, and make them improve rapidly and reach a physiological repair state, rather than developing in a deeper pathological direction, is an extremely important key issue for the stasis area. On this basis, paying more attention to the prevention and treatment of stasis pathological changes can be beneficial to the recovery of burn damage.

[0092] The burn medicine of this technical solution can effectively solve the problems of microcirculation disorders, tissue hypoxia and ischemia in the treatment of first-degree, superficial second-degree, deep second-degree and third-degree burns, revive and regenerate the stagnant and congested areas, reduce the area of ​​coagulation necrosis, and promote the regeneration of the skin, muscles and bones of the wound surface, thereby restoring to the pre-illness state, "hair grows, and beauty is as before."

[0093] In summary, the burn medicine of this technical solution achieves the expected purpose through the method of wet compress and soaking, under the guidance of the theoretical system of traditional Chinese medicine, through the combination of "monarch, minister, assistant and envoy", and solves some burn problems.

[0094] The above is only a preferred embodiment of the present invention. It should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the principles of the present invention, and these improvements and modifications should also be considered as the protection scope of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention shall be implemented according to the conventional means in the art unless otherwise specified and limited.

Claims

1. A highly effective burn medicine, characterized in that: The invention comprises the following raw materials in parts by weight: 0.8-1.5 parts of Polygonum cuspidatum, 0.8-1.5 parts of Rhubarb, 0.8-1.5 parts of Sanguisorba officinalis, 0.8-1.5 parts of Borneolum, 0.8-1.5 parts of Euphorbia trichosanthis, 0.8-1.5 parts of Bletilla striata, 0.8-1.5 parts of Phellodendron chinense, 0.8-1.5 parts of Lithospermum officinale, 0.8-1.5 parts of Honeysuckle, 0.8-1.5 parts of Sophora flavescens, 0.8-1.5 parts of frankincense, 0.8-1.5 parts of Myrrh, 0.8-1.5 parts of Angelica sinensis, 0.8-1.5 parts of Astragalus, 0.8-1.5 parts of Moutan bark, 0.8-1.5 parts of Rehmannia root, and 800-1500 parts of water.

2. A highly effective burn medicine according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 1 part of Polygonum cuspidatum, 1 part of Rhubarb, 1 part of Sanguisorba officinalis, 1 part of Borneolum, 1 part of Herba Euphorbiae Ichthyophthirius, 1 part of Bletilla striata, 1 part of Phellodendron chinense, 1 part of Lithospermum officinale, 1 part of Honeysuckle, 1 part of Sophora flavescens, 1 part of Frankincense, 1 part of Myrrh, 1 part of Angelica sinensis, 1 part of Astragalus, 1 part of Moutan Cortex, 1 part of Rehmannia glutinosa, and 1000 parts of water.

3. A highly effective burn medicine according to any one of claims 1-2, characterized in that: The highly effective burn medicine is a decoction.

4. A method for preparing a highly effective burn medicine, comprising preparing the highly effective burn medicine according to any one of claims 1 to 2, characterized in that: The following steps are involved: Bring to a boil over high heat, start timing, then turn down the heat and simmer for another 30 minutes over low heat. Stir evenly, let it sit for 1 hour, then cool to room temperature to form a syrup for later use.

5. A method for preparing a highly effective burn medicine, comprising preparing the highly effective burn medicine according to any one of claims 1 to 2, characterized in that: The following steps are involved: S1. Pretreatment: accurately weigh Polygonum cuspidatum, Rhubarb, Sanguisorba officinalis, Borneolum, Herba Euphorbiae, Bletilla striatae, Cortex Phellodendri, Lithospermum officinale, Flos Lonicerae, Sophorae Flavescentis, Olibanum, Myrrha, Angelicae Sinensis, Astragalus, Cortex Moutan, and Radix Rehmanniae in equal proportions, mix them, and put them into a Chinese medicine decoction bag; S2, high heat shock: put the Chinese medicine decoction bag into the pot, add 1000mL of pure water, and quickly boil the water with high heat until the water temperature reaches 100℃, and start timing for 5 minutes; S3, frequency conversion, alternating between medium and strong heat: adjust the heat to medium heat, keep it for 3 minutes, then reduce the heat to low heat and simmer for 20 minutes; S4, ultrasonic-assisted impregnation: After simmering for 20 minutes, turn off the heat; put an ultrasonic generator into the pot, turn on the ultrasonic function, and ultrasonicate for 10 minutes; S5. Natural precipitation and cooling: After the ultrasonic treatment, take out the medicine liquid together with the decoction bag, and let it precipitate naturally for 1 hour to form a medicine solution for use.

6. The method for preparing a highly effective burn medicine according to claim 5, characterized in that: During the decocting process over low heat in step S3, stirring is performed every 5 minutes.

7. The method for preparing a highly effective burn medicine according to claim 5, characterized in that: In S4, the ultrasonic generator performs ultrasonic treatment at a power of 10W to 30W.

8. Use of the high-efficiency burn medicine according to any one of claims 1 to 2 in preparing medicine for treating burn wounds.

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