Sampler for tumor treatment

Abstract

The invention relates to the technical field of sampling devices, and discloses a sampling device for tumor treatment, which comprises an elastic gas film, a controllable drawing mechanism and a pressure display mechanism, the longitudinal hollow shell is fixedly installed on the circumferential face of the liquid pumping cylinder and can reflect the liquid pressure in the annular liquid buffering cavity, and the second rubber plug is placed in the longitudinal hollow shell and moves upwards after being subjected to the liquid pressure. According to the sampler for tumor treatment, in the lumbar puncture process of a patient, the function of detecting intracranial pressure in real time can be achieved, the function of measuring the total collecting amount of cerebrospinal fluid can also be achieved, operation steps in the puncture process are reduced, and therefore the sampling efficiency is improved; the device can adjust the maximum sampling capacity of equipment according to actual conditions, so that the sampling capacity can be controlled.

Description

Technical Field

[0001] The invention relates to the technical field of samplers, in particular to a sampler for tumor treatment. Background Art

[0002] With the increasing incidence of intracranial metastasis of solid tumors, cerebrospinal fluid exfoliative cytology is becoming more and more critical for disease diagnosis and efficacy evaluation. In this process, lumbar puncture to obtain cerebrospinal fluid is more important and frequent. However, during the lumbar puncture, the process is cumbersome and fragmented due to the need to measure intracranial pressure, count the amount of cerebrospinal fluid collected, and perform aseptic operations. Moreover, as the amount of cerebrospinal fluid collected increases, the intracranial pressure fluctuates more, which may induce brain herniation. Therefore, it is particularly necessary to detect changes in intracranial pressure fluctuations. Summary of the invention

[0003] In view of the deficiencies in the prior art, the present invention provides a sampler for tumor treatment, which, during the process of lumbar puncture of a patient, has the function of both real-time detection of intracranial pressure and measurement of the total amount of cerebrospinal fluid collected, so as to reduce the operating steps of the puncture process and improve the efficiency of sampling. In addition, the device can adjust the maximum sampling capacity of the equipment according to actual conditions, so as to have the controllable ability of the sampling capacity, thereby solving the above-mentioned technical problems.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a sampler for tumor treatment, comprising a liquid extraction cylinder with a liquid suction cavity arranged inside, a needle tube structure integrally arranged at one end of the liquid extraction cylinder and capable of being inserted into the patient's skull, a pinhole structure arranged inside the needle tube structure and capable of sucking the liquid in the patient's skull into the liquid suction cavity, a No. 1 component perforation arranged at the other end of the liquid extraction cylinder, a limiting ear integrally arranged at the end of the liquid extraction cylinder near the No. 1 component perforation, an annular liquid cache cavity with an inner concave structure arranged on the circumferential surface of the needle tube structure, and a capacity scale value arranged on the outer circumferential surface of the liquid extraction cylinder and capable of displaying the liquid capacity in the liquid suction cavity, and also comprising an elastic air membrane, the elastic air membrane being embedded in the outer circumferential surface at the edge of the annular liquid cache cavity, the interior of the liquid extraction cylinder is provided with a No. 1 liquid flow hole connected to one end of the annular liquid cache cavity, the The liquid pumping cylinder is provided with a No. 2 liquid flow hole connected to the external space of the liquid pumping cylinder on the circumferential surface near the limiting ear; a controllable pulling and drawing mechanism, inside which is provided with a limiting fixing plate fixedly installed on the periphery of one end of the liquid pumping cylinder and with the end face parallel to the corresponding end face of the liquid pumping cylinder, a No. 1 rubber plug located in the liquid suction cavity and capable of allowing the liquid to flow during the movement, an externally threaded rod that passes through the limiting fixing plate and can drive the No. 1 rubber plug to move axially, and a threaded sleeve that is placed on the periphery of the rod body of the externally threaded rod through a threaded structure and limits the maximum suction amount caused by the No. 1 rubber plug by colliding with the limiting fixing plate; and a pressure display mechanism, inside which is provided with a longitudinal hollow shell fixedly installed on the circumferential surface of the liquid pumping cylinder and capable of reflecting the liquid pressure inside the annular liquid buffer cavity, and a No. 2 rubber plug placed in the longitudinal hollow shell and moving upward after being subjected to the liquid pressure.

[0005] Preferably, the outer circumferential surface of the elastic air membrane is flush with the outer circumferential surface of the liquid extraction cylinder.

[0006] Preferably, the elastic air membrane is an annular structure made of a ductile rubber material.

[0007] Preferably, the controllable pulling and pulling mechanism includes an externally threaded rod that passes through the through-hole of component No. 1 and can move axially along the through-hole of component No. 1, a limiting fixing plate located at the periphery of one end of the liquid pumping cylinder and with an end face parallel to the corresponding end face of the liquid pumping cylinder, and a threaded sleeve, the center of the limiting fixing plate is provided with a through-hole of component No. 2 for the externally threaded rod to pass through, one end of the externally threaded rod extends to the interior of the liquid suction cavity, and a No. 1 rubber plug is fixedly installed on the end, and a force plate is fixedly installed on the other end of the externally threaded rod, and one end of the limiting fixing plate is provided with a transverse fixing rod with an integral structure therewith, and the transverse fixing rod is fixedly installed on the corresponding end face of the limiting ear through a fixed connecting plate, and an internally threaded hole is provided at the center of the threaded sleeve, and the internally threaded hole is installed on the periphery of the rod body of the externally threaded rod through a threaded structure, and the threaded sleeve is located in the area between the liquid pumping cylinder and the limiting fixing plate.

[0008] Preferably, the threaded structure includes an internal threaded structure arranged in the internal threaded hole and an external threaded structure arranged at the rod body of the external threaded rod, and the internal threaded structure matches the external threaded structure.

[0009] Preferably, the No. 1 rubber stopper is a plunger structure made of rubber, and the structural radius of the outer circumferential surface of the plunger structure matches the structural radius of the liquid suction cavity.

[0010] Preferably, the pressure display mechanism includes a longitudinal hollow shell, the bottom end of the longitudinal hollow shell is provided with an arc-shaped fixing plate which is an integral structure therewith and fixedly mounted on the circumferential side of the liquid suction cylinder, the interior of the longitudinal hollow shell is provided with a longitudinal component active cavity, the bottom end of the longitudinal component active cavity is provided with a No. 3 liquid flow hole connected to the No. 2 liquid flow hole, the top of the longitudinal component active cavity is provided with a gas compensation hole connected to the external space, the longitudinal hollow shell is provided with a No. 2 rubber plug which can move axially along the longitudinal component active cavity inside the longitudinal component active cavity, the outer circumferential surface of the longitudinal hollow shell is provided with a pressure scale value in an axial state, and the closed area between the inner circumferential surface of the elastic air film and the bottom end of the No. 2 rubber plug is filled with a buffer solution.

[0011] Preferably, the No. 2 rubber stopper generates axial movement under the action of liquid buoyancy and its own rotational gravity.

[0012] Preferably, the pressure scale value can reflect the pressure value of the buffer solution on the elastic air membrane.

[0013] Compared with the prior art, the present invention provides a sampler for tumor treatment, which has the following beneficial effects:

[0014] This sampler for tumor treatment has the function of real-time detection of intracranial pressure and measurement of the total amount of cerebrospinal fluid collected during lumbar puncture of patients, so as to reduce the operating steps of the puncture process and improve the efficiency of sampling. In addition, the device can adjust the maximum sampling capacity of the equipment according to actual conditions, so as to have the controllable ability of sampling capacity. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 A perspective view of the present invention;

[0016] Figure 2 is a three-dimensional cross-sectional view of the present invention;

[0017] Figure 3 It is a three-dimensional cross-sectional view of the liquid extraction cylinder in the present invention;

[0018] Figure 4 It is a three-dimensional diagram of the controllable drawing mechanism of the present invention;

[0019] Figure 5 It is a three-dimensional cross-sectional view of the controllable drawing mechanism of the present invention;

[0020] Figure 6 It is a three-dimensional diagram of the pressure display mechanism in the present invention;

[0021] Figure 7 It is a three-dimensional cross-sectional view of the pressure display mechanism in the present invention.

[0022] Wherein: 1. Liquid suction cylinder; 2. Liquid suction cavity; 3. Needle tube structure; 4. Pinhole structure; 5. Perforation of component No. 1; 6. Limiting ear; 7. Annular liquid buffer cavity; 8. Elastic gas film; 9. Liquid flow hole No. 1; 10. Liquid flow hole No. 2; 11. Capacity scale value; 12. Controllable pulling and pulling mechanism; 121. External threaded rod; 122. Rubber plug No. 1; 123. Force plate; 124. Limiting fixing plate; 125. Horizontal fixing rod; 126. Fixed connecting plate; 127. Perforation of component No. 2; 128. Threaded sleeve; 129. Internal threaded hole; 13. Pressure display mechanism; 131. Arc fixing plate; 132. Longitudinal hollow shell; 133. Longitudinal component active cavity; 134. Liquid flow hole No. 3; 135. Gas compensation hole; 136. Rubber plug No. 2; 137. Pressure scale value. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] See also Figure 1 , Figure 2 and Figure 3 , a sampler for tumor treatment, comprising a liquid extraction cylinder 1 with a liquid suction cavity 2 arranged inside, a needle tube structure 3 integrally arranged at one end of the liquid extraction cylinder 1 and capable of being inserted into the patient's skull, a pinhole structure 4 arranged inside the needle tube structure 3 and capable of sucking the liquid in the patient's skull into the liquid suction cavity 2, a No. 1 component perforation 5 arranged at the other end of the liquid extraction cylinder 1, a limiting ear 6 integrally arranged on the liquid extraction cylinder 1 near the end of the No. 1 component perforation 5, an annular liquid cache cavity 7 arranged on the circumferential surface of the needle tube structure 3 and having an inner concave structure, and a capacity scale value 11 arranged on the outer circumferential surface of the liquid extraction cylinder 1 and capable of displaying the liquid capacity in the liquid suction cavity 2, the elastic air membrane 8 is embedded in the outer circumferential surface at the edge of the annular liquid cache cavity 7, in order to improve the flatness of the device at the deep position, it is necessary to make the outer circumferential surface of the elastic air membrane 8 flush with the outer circumferential surface of the liquid extraction cylinder 1 State, in order to be able to transmit liquid pressure, it is necessary to make the elastic air membrane 8 an annular structure made of ductile rubber material, the interior of the liquid pumping cylinder 1 is provided with a No. 1 liquid flow hole 9 connected to one end of the annular liquid buffer chamber 7, and the liquid pumping cylinder 1 is provided with a No. 2 liquid flow hole 10 connected to the external space of the liquid pumping cylinder 1 on the circumferential surface close to the limiting ear 6. When working, the circumferential surface of the liquid pumping cylinder 1 is held, and it is necessary to ensure that the longitudinal hollow shell 132 is in the longitudinal direction, and the gas compensation hole 135 is located directly above, and then the needle tube structure 3 is inserted into the patient's skull, and then the needle hole structure 4 is inserted into the area where cerebrospinal fluid is taken. At this time, the pressure of the tissue fluid in this area will produce pressure toward the central area on the outer circumferential surface of the elastic air membrane 8, and this pressure will cause the elastic air membrane 8 to be concave, so that the elastic air membrane 8 produces an isobaric force on the buffer solution, thereby transmitting the pressure in the skull at this time.

[0025] In order to achieve the quantitative extraction and discharge of cerebrospinal fluid, please refer to Figure 1 , Figure 2 , Figure 4 and Figure 5, it is necessary to set up a controllable pulling and drawing mechanism 12, which is internally provided with a limiting fixing plate 124 fixedly installed on the periphery of one end of the liquid pumping cylinder 1 and whose end face is parallel to the corresponding end face of the liquid pumping cylinder 1, a No. 1 rubber plug 122 located inside the liquid suction cavity 2 and capable of allowing the liquid to flow during the movement, an externally threaded rod 121 that passes through the limiting fixing plate 124 and can drive the No. 1 rubber plug 122 to move axially, and a threaded sleeve 128 that is placed on the periphery of the rod body of the externally threaded rod 121 through a threaded structure and collides with the limiting fixing plate 124 to limit the maximum suction amount caused by the No. 1 rubber plug 122. First, push the force plate 123 so that the No. 1 rubber plug 122 The end face of the plug 122 abuts against the discharge port of the needle tube structure 3, and then the threaded sleeve 128 is rotated to adjust the distance between the threaded sleeve 128 and the limiting fixing plate 124, which is L. At this time, the maximum extractable capacity of cerebrospinal fluid V = the bottom area Sbottom of the liquid suction cavity 2 * L, and the capacity V can be observed by observing the corresponding capacity scale value 11 of the No. 1 rubber plug 122 before and after the activity. When extracting cerebrospinal fluid, pull the force plate 123 outward until the threaded sleeve 128 abuts against the end face of the limiting fixing plate 124, so that the cerebrospinal fluid with a capacity V unit can be extracted, thereby realizing the quantitative extraction and discharge function of the cerebrospinal fluid.

[0026] For the specific structure of the controllable pulling mechanism 12, please refer to Figure 4 and Figure 5 , including an externally threaded rod 121 that passes through the through hole 5 of the first component and can move axially along the through hole 5 of the first component, a limiting fixing plate 124 located at the periphery of one end of the liquid pumping cylinder 1 and with an end face parallel to the corresponding end face of the liquid pumping cylinder 1, and a threaded sleeve 128, the center of the limiting fixing plate 124 is provided with a through hole 127 of the second component for the externally threaded rod 121 to pass through, one end of the externally threaded rod 121 extends to the interior of the liquid suction cavity 2, and a No. 1 rubber plug 122 is fixedly installed on the end, the No. 1 rubber plug 122 is a plunger structure made of rubber, and the structural radius of the outer circumferential surface of the plunger structure matches the structural radius of the liquid suction cavity 2, and the other end of the externally threaded rod 121 is fixedly installed with a The force plate 123, one end of the limiting fixing plate 124 is provided with a transverse fixing rod 125 of an integral structure therewith, the transverse fixing rod 125 is fixedly mounted on the corresponding end face of the limiting ear 6 through a fixed connecting plate 126, and an internal threaded hole 129 is provided at the center of the threaded sleeve 128, and the internal threaded hole 129 is installed on the periphery of the rod body of the external threaded rod 121 through a threaded structure. Specifically, the threaded structure includes an internal threaded structure arranged in the internal threaded hole 129 and an external threaded structure arranged at the rod body of the external threaded rod 121, and the internal threaded structure matches the external threaded structure, and the threaded sleeve 128 is located in the area between the liquid extraction cylinder 1 and the limiting fixing plate 124.

[0027] In order to be able to respond to the intracranial tissue fluid pressure in real time, please refer to Figure 1 , Figure 2 , Figure 6 and Figure 7 , it is necessary to set up a pressure display mechanism 13, inside which is provided a longitudinal hollow shell 132 fixedly mounted on the circumferential surface of the liquid suction cylinder 1 and capable of reflecting the liquid pressure inside the annular liquid buffer chamber 7, and a No. 2 rubber plug 136 placed inside the longitudinal hollow shell 132 and moving upward after being subjected to liquid pressure. The buffer solution enters the interior of the longitudinal component active cavity 133 through the No. 3 liquid flow hole 134, and the buffer solution generates an upward buoyancy on the No. 2 rubber plug 136, which causes the No. 2 rubber plug 136 to move upward. By observing the pressure scale value 137 corresponding to the bottom of the No. 2 rubber plug 136, the pressure of the patient's intracranial tissue fluid at this time can be known.

[0028] For the specific structure of the pressure display mechanism 13, please refer to Figure 6 and Figure 7 , including a longitudinal hollow shell 132, the bottom end of the longitudinal hollow shell 132 is provided with an arc-shaped fixing plate 131 which is integrally structured with it and fixedly mounted on the circumferential side of the liquid pumping cylinder 1, the interior of the longitudinal hollow shell 132 is provided with a longitudinal component active cavity 133, the bottom end of the longitudinal component active cavity 133 is provided with a No. 3 liquid flow hole 134 connected to the No. 2 liquid flow hole 10, the top end of the longitudinal component active cavity 133 is provided with a gas compensation hole 135 connected to the external space, the longitudinal hollow shell 132 is provided with a gas compensation hole 135 connected to the external space, and the longitudinal hollow shell 132 is provided with a gas compensation hole 135 connected to the external space. A No. 2 rubber plug 136 capable of axially moving along the longitudinal component active cavity 133 is placed inside the longitudinal component active cavity 133. The No. 2 rubber plug 136 generates axial movement under the action of liquid buoyancy and its own rotational gravity. The outer circumferential surface of the longitudinal hollow shell 132 is provided with an axial state pressure scale value 137. The pressure scale value 137 can reflect the pressure value of the buffer solution on the elastic air membrane 8. The closed area between the inner circumferential surface of the elastic air membrane 8 and the bottom end of the No. 2 rubber plug 136 is filled with a buffer solution.

[0029] When in use, hold the circumferential surface of the liquid pumping cylinder 1, and ensure that the longitudinal hollow shell 132 is in the longitudinal direction, and the gas compensation hole 135 is located directly above, push the force plate 123, so that the end surface of the No. 1 rubber plug 122 contacts the discharge port of the needle tube structure 3, and then rotate the threaded sleeve 128 to adjust the distance between the threaded sleeve 128 and the limit fixing plate 124. The capacity V can be observed by observing the capacity scale value 11 corresponding to the No. 1 rubber plug 122 before and after the activity, and then the needle tube is moved. The structure 3 is inserted into the patient's skull, and then the pinhole structure 4 is inserted into the area for collecting cerebrospinal fluid. At this time, the pressure of the tissue fluid in this area will generate pressure on the outer circumferential surface of the elastic air membrane 8 toward the central area. This pressure will cause the elastic air membrane 8 to be concave, thereby causing the elastic air membrane 8 to generate an isobaric force on the buffer solution, transmitting the pressure in the skull at this time, pulling the force plate 123 outward until the threaded sleeve 128 contacts the end face of the limit fixing plate 124, and the cerebrospinal fluid with a volume V unit can be extracted from the surface.

[0030] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A sampler for tumor treatment, comprising a liquid extraction cylinder (1) having a liquid suction cavity (2) therein, a needle tube structure (3) integrally arranged at one end of the liquid extraction cylinder (1) and capable of being inserted into a patient's skull, a pinhole structure (4) arranged inside the needle tube structure (3) and capable of sucking liquid from the patient's skull into the liquid suction cavity (2), a No. 1 component perforation (5) arranged at the other end of the liquid extraction cylinder (1), a stopper ear (6) integrally arranged at the end of the No. 1 component perforation (5) near the No. 1 component perforation (5), an annular liquid buffer cavity (7) of an inner concave structure arranged on the circumferential surface of the needle tube structure (3), and a capacity scale value (11) arranged on the outer circumferential surface of the liquid extraction cylinder (1) and capable of displaying the liquid capacity in the liquid suction cavity (2), characterized in that: Also includes, An elastic air membrane (8), wherein the elastic air membrane (8) is embedded in the outer circumferential surface at the edge of the annular liquid cache cavity (7), the interior of the liquid extraction cylinder (1) is provided with a No. 1 liquid flow hole (9) connected to one end of the annular liquid cache cavity (7), and the liquid extraction cylinder (1) is provided with a No. 2 liquid flow hole (10) connected to the external space of the liquid extraction cylinder (1) on the circumferential surface close to the limiting ear (6); A controllable pulling and drawing mechanism (12) is provided inside thereof with a limit fixing plate (124) fixedly mounted on the periphery of one end of a liquid pumping cylinder (1) and having an end face parallel to the corresponding end face of the liquid pumping cylinder (1), a No. 1 rubber plug (122) located inside a liquid suction cavity (2) and capable of allowing liquid to flow during movement, an externally threaded rod (121) penetrating the limit fixing plate (124) and capable of driving the No. 1 rubber plug (122) to move axially, and a threaded sleeve (128) disposed on the periphery of the rod body of the externally threaded rod (121) through a threaded structure and colliding with the limit fixing plate (124) to limit the maximum suction amount caused by the No. 1 rubber plug (122); And a pressure display mechanism (13), which is provided with a longitudinal hollow shell (132) fixedly mounted on the circumferential surface of the liquid pumping cylinder (1) and capable of reflecting the liquid pressure inside the annular liquid buffer chamber (7), and a No. 2 rubber plug (136) placed inside the longitudinal hollow shell (132) and moving upward after being subjected to the liquid pressure.

2. A sampler for tumor treatment according to claim 1, characterized in that: The outer circumferential surface of the elastic air membrane (8) is flush with the outer circumferential surface of the liquid extraction cylinder (1).

3. A sampler for tumor treatment according to claim 2, characterized in that: The elastic air membrane (8) is an annular structure made of a ductile rubber material.

4. A tumor treatment sampler according to claim 3, characterized in that: The controllable pulling and pulling mechanism (12) comprises an externally threaded rod (121) which passes through the through hole (5) of the first component and can move axially along the through hole (5) of the first component, a limiting fixing plate (124) which is located at the periphery of one end of the liquid pumping cylinder (1) and whose end face is parallel to the corresponding end face of the liquid pumping cylinder (1), and a threaded sleeve (128), wherein the center of the limiting fixing plate (124) is provided with a through hole (127) of the second component for the externally threaded rod (121) to pass through, one end of the externally threaded rod (121) extends to the interior of the liquid suction cavity (2), and the end is fixedly mounted with a rubber plug (122), and the externally threaded rod A force plate (123) is fixedly installed at the other end of the (121), and a transverse fixing rod (125) of an integral structure is provided at one end of the limit fixing plate (124), and the transverse fixing rod (125) is fixedly installed on the corresponding end surface of the limit ear (6) through a fixed connecting plate (126), and an internal threaded hole (129) is provided at the center of the threaded sleeve (128), and the internal threaded hole (129) is installed on the periphery of the rod body of the external threaded rod (121) through a threaded structure, and the threaded sleeve (128) is located in the area between the liquid extraction cylinder (1) and the limit fixing plate (124).

5. A sampler for tumor treatment according to claim 4, characterized in that: The thread structure comprises an internal thread structure arranged in the internal thread hole (129) and an external thread structure arranged at the rod body of the external thread rod (121), and the internal thread structure matches the external thread structure.

6. A sampler for tumor treatment according to claim 5, characterized in that: The first rubber stopper (122) is a plunger structure made of rubber, and the structural radius of the outer circumferential surface of the plunger structure matches the structural radius of the liquid suction cavity (2).

7. A tumor treatment sampler according to claim 6, characterized in that: The pressure display mechanism (13) comprises a longitudinal hollow shell (132), the bottom end of which is provided with an arc-shaped fixing plate (131) which is integrally structured with the shell and fixedly mounted on the circumferential side of the liquid pumping cylinder (1), the interior of which is provided with a longitudinal component movable cavity (133), the bottom end of which is provided with a third liquid flow hole (134) which is connected to the second liquid flow hole (10), and the longitudinal component movable cavity (133) is provided with a third liquid flow hole (134) which is connected to the second liquid flow hole (10). The top of the longitudinal hollow shell (132) is provided with a gas compensation hole (135) connected to the external space, and a second rubber plug (136) capable of axially moving along the longitudinal component active cavity (133) is placed inside the longitudinal component active cavity (133). The outer circumferential surface of the longitudinal hollow shell (132) is provided with an axial pressure scale value (137), and a buffer solution is filled in the closed area between the inner circumferential surface of the elastic gas membrane (8) and the bottom end of the second rubber plug (136).

8. A sampler for tumor treatment according to claim 7, characterized in that: The second rubber stopper (136) moves axially under the action of the liquid buoyancy and its own rotational gravity.

9. A sampler for tumor treatment according to claim 8, characterized in that: The pressure scale value (137) can reflect the pressure value of the buffer solution on the elastic air membrane (8).

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