Enterogram detection device combining strong-tropism magnetic concentrator and gradiometer

Abstract

The invention discloses a magnetoenterogram detection device combining a strong-tropism magnetic concentrator and a gradiometer, and belongs to the technical field of biological weak magnetic signal detection, the device comprises a magnetic concentrator, a gradiometer, a conditioning circuit, a data acquisition system and a diagnosis bed; wherein the magnetic gathering device is located above the diagnosis bed, the gradiometer is located above the magnetic gathering device, and the gradiometer, the conditioning circuit and the data acquisition system are electrically connected in sequence; the diagnosis bed is made of a non-magnetic material and is used for placing a target body to be subjected to magnetoenterogram detection; the magnetic gathering device is used for gathering and amplifying magnetic gradient signals generated by intestinal activity of a target body; the gradiometer is used for receiving the amplified magnetic gradient signal and converting the received magnetic gradient signal into a corresponding analog voltage signal; the conditioning circuit is used for preprocessing the analog voltage signal; and the data acquisition system is used for converting the preprocessed analog voltage signal into a corresponding digital signal, so as to complete the enteromagnetogram detection. The signal-to-noise ratio and the sensitivity of intestinal magnetic field detection can be effectively improved.

Description

Technical Field

[0001] This invention relates to the field of bioweak magnetic signal detection technology, and in particular to a magnetoenterography detection device that combines a strong directional magnetic aggregator with a gradient meter. Background Technology

[0002] Methods for diagnosing intestinal diseases include ultrasound, abdominal X-ray, CT angiography, and colonoscopy. In recent years, a new, non-invasive, radiation-free method that can reflect the dynamics of intestinal activity—mammatrography—has been under development.

[0003] After digestion in the stomach, chyme enters the intestines. Stimulation of the interstitial cells in the intestinal wall triggers slow-wave electrical rhythms, driving the longitudinal and circular muscles within the intestinal wall to contract and relax alternately with a 90-degree phase difference. This peristalsis pushes the chyme towards the end of the intestine. Simultaneously, a very weak magnetic field is generated along with the slow-wave electrical rhythm. Using an ultra-high sensitivity magnetic flux sensor to detect this external magnetic field in real time, a dynamic enteromagnetism spectrum can be generated, enabling the diagnosis of abnormalities in intestinal electrical activity and function. However, this signal differs from typical cardiac magnetoencephalograms by approximately 10... -10 Compared to T, the intestinal magnetic gradient signal is approximately 10. -12 T is about 100 times lower. Moreover, the detection of such weak biosignals is affected by environmental interference such as geomagnetism. Therefore, current technology cannot accurately detect enteromagnetic gradient signals. Summary of the Invention

[0004] This invention provides a magnetoenterography detection device that combines a strong directional magnetic aggregator with a gradient meter to solve the technical problem that existing technologies cannot accurately detect the magnetoenteric gradient signal.

[0005] To solve the above-mentioned technical problems, the present invention provides the following technical solution:

[0006] A magnetoenterography (MEG) detection device combining a strong directional magnetic aggregator and a gradiometer includes: a magnetic aggregator, a gradiometer, a conditioning circuit, a data acquisition system, and an examination bed; wherein,

[0007] The magnetic concentrator is located above the examination bed, the gradient meter is located above the magnetic concentrator, the gradient meter is electrically connected to the conditioning circuit, and the conditioning circuit is electrically connected to the data acquisition system;

[0008] The examination bed is made of non-magnetic material and is used to place the target body to be detected by enteromagnetism.

[0009] The magnetic aggregator is used to amplify the magnetic gradient signal generated by the intestinal activity of the target body; the gradient meter is used to receive the amplified magnetic gradient signal and convert the received magnetic gradient signal into a corresponding analog voltage signal; the conditioning circuit is used to preprocess the analog voltage signal; the data acquisition system is used to convert the preprocessed analog voltage signal into a corresponding digital signal to complete the enteromagnetic detection.

[0010] Furthermore, the magnetic concentrator includes: a magnetic concentrator body and a shielding shell;

[0011] The shielding shell is a cylindrical structure with one end open and the other end closed. The sidewalls of the cylindrical structure are made of a material with a magnetic permeability greater than 5000, and the end face of the cylindrical structure is made of a non-magnetic material. The shielding shell is used to shield magnetic noise in a preset direction. The closed end of the shielding shell faces the gradient meter, and the open end of the shielding shell faces the target body.

[0012] The magnetic collector body is located inside the shielding shell.

[0013] Furthermore, the magnetic concentrator body comprises: a first body and a second body;

[0014] The first main body is a frustum-shaped structure, and the second main body is a cylindrical structure; the first end face of the first main body is connected to the second main body, and the second end face of the first main body faces the target body, wherein the area of ​​the second end face is larger than the area of ​​the first end face; one end of the second main body is connected to the first main body, and the other end is connected to the top of the shielding shell, and the first main body and the second main body are coaxially arranged.

[0015] Furthermore, the first main body and the second main body are integrally formed.

[0016] Furthermore, the magnetic concentrator is made of a material with a magnetic permeability greater than 5000.

[0017] Furthermore, the gradient meter is a SQUID gradient meter.

[0018] Furthermore, the SQUID gradient meter includes a gradient coil, a SQUID module, a housing, and a heat insulation plate;

[0019] The shell is made of non-magnetic Dewar material; the shell includes an inner shell and an outer shell, with a sandwich layer between the inner shell and the outer shell, forming a vacuum environment within the sandwich layer; the shell is filled with liquid helium;

[0020] The gradient coil, the SQUID module, and the heat insulation plate are all located inside the housing; wherein, the gradient coil is coupled to the SQUID module, the SQUID module is electrically connected to the conditioning circuit, and the heat insulation plate is disposed at one end of the housing to isolate the temperature outside the housing.

[0021] Furthermore, the gradient coil includes: a first coil and a second coil of the same size; the first coil and the second coil are parallel and coaxially arranged; and the magnetic concentrator body is also coaxially arranged with the gradient coil.

[0022] Furthermore, the conditioning circuit includes: an amplifier circuit and a low-pass filter circuit;

[0023] The amplifier circuit is used to amplify the analog voltage signal, and the low-pass filter circuit is used to perform low-pass filtering on the amplified analog voltage signal.

[0024] Furthermore, the examination bed includes: a bed frame and a bed board;

[0025] The bed board and the bed frame are slidably connected in both the longitudinal and transverse directions to enable movement in the XY directions.

[0026] The technical solution provided by this invention first uses a magnetic concentrator to directionally amplify the enteromagnetic gradient signal, suppressing magnetic noise outside the sensitive direction; then, a geomagnetic interference-resistant SQUID gradiometer receives the amplified enteromagnetic gradient signal, eliminating geomagnetic interference, and outputting a voltage signal proportional to the enteromagnetic gradient signal; finally, a conditioning circuit and a data acquisition system are used to complete the enteromagnetic imaging. The beneficial effects include at least the following:

[0027] 1. The enteromagnetism detection device provided by this invention can be widely used in the non-invasive examination and diagnosis of clinical intestinal diseases. Its highly sensitive SQUID gradient meter can detect weak intestinal magnetic field signals (amplitude approximately 10). -12 T) can also counteract geomagnetic interference.

[0028] 2. The strong directional magnetic concentrator provided by the present invention can shield magnetic noise outside the sensitive direction, directionally concentrate magnetic flux, and confine the magnetic field to the gradient coil of the SQUID gradiometer, thereby improving the detection sensitivity.

[0029] 3. The magnetoenterography detection device of the present invention utilizes a magnetic concentrator to amplify the magnetoenteric gradient signal and cancel geomagnetic interference and shield magnetic noise, thereby further improving the detection signal-to-noise ratio and sensitivity of the magnetoenterography detection device. Attached Figure Description

[0030] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0031] Figure 1 This is a schematic diagram of the magnetoenterography detection device combining a strong directional magnetic aggregator and a gradient meter provided in an embodiment of the present invention.

[0032] Figure 2 This is a schematic diagram of the intestinal magnetic gradient signal;

[0033] Figure 3 This is a schematic diagram of a gradient coil.

[0034] Figure 4 This is a schematic diagram of the magnetic concentrator amplification principle provided in an embodiment of the present invention;

[0035] Figure 5 This is a schematic diagram of the main body of the magnetic concentrator provided in an embodiment of the present invention;

[0036] Figure 6 These are magnified images of magnetic signals in different directions provided by the magnetic concentrator in the embodiments of the present invention; wherein, (a) is a magnified image of the magnetic signal in the z direction and (b) is a magnified image of the magnetic signal in the x direction.

[0037] Explanation of reference numerals in the attached figures:

[0038] 1. Magnetic concentrator;

[0039] 11. Magnetic concentrator body; 12. Shielding shell;

[0040] 121. Side wall; 122. End face;

[0041] 2. Gradient meter;

[0042] 21. Gradient coil; 22. SQUID module; 23. Liquid helium; 24. Housing; 25. Heat insulation plate;

[0043] 3. Conditioning circuit;

[0044] 4. Data acquisition system;

[0045] 5. Examination bed. Detailed Implementation

[0046] To make the objectives, technical solutions, and advantages of the present invention clearer, the embodiments of the present invention will be described in further detail below with reference to the accompanying drawings.

[0047] This embodiment provides a magnetoenterography detection device that combines a strong directional magnetic aggregator with a gradient meter, such as... Figure 1 As shown, the enteromagnetism detection device includes: a magnetic aggregator 1, a gradient meter 2, a conditioning circuit 3, a data acquisition system 4, and an examination bed 5. The magnetic aggregator 1 is located above the examination bed 5 (it can be mounted on the examination bed 5 using a structure such as a mounting bracket), and the gradient meter 2 is located above the magnetic aggregator 1 (it can be fixed using a mounting bracket). The gradient meter 2 is electrically connected to the conditioning circuit 3, and the conditioning circuit 3 is electrically connected to the data acquisition system 4. The examination bed 5 is made of non-magnetic material and is used to place the target body to be detected by enteromagnetism. The magnetic aggregator 1 is strongly directional and is used to amplify the magnetic gradient signal generated by the intestinal activity of the target body. The gradient meter 2 is used to receive the amplified magnetic gradient signal and convert the received magnetic gradient signal into a corresponding analog voltage signal. The conditioning circuit 3 is used to preprocess the analog voltage signal. The data acquisition system 4 is used to convert the preprocessed analog voltage signal into a corresponding digital signal to complete the enteromagnetism detection.

[0048] Specifically, the gradient meter 2 is a SQUID gradient meter, which includes a gradient coil 21, a SQUID module 22, a housing 24, and a heat insulation plate 25. The gradient coil 21, SQUID module 22, and heat insulation plate 25 are all located inside the housing 24. The gradient coil 21 is coupled to the SQUID module 22, which is electrically connected to the conditioning circuit 3. The heat insulation plate 25 is located at one end of the housing 24 to insulate it from external temperatures. The housing 24 is made of non-magnetic Dewar material. The housing 24 includes an inner housing and an outer housing, with a sandwich layer forming a vacuum environment for thermal insulation. The housing 24 is filled with liquid helium 23 to maintain the cryogenic environment required for the normal operation of the SQUID module 22 without obstructing magnetic field transmission. The SQUID module 22 consists of a Josephson junction superconducting ring and cryogenic electronic circuitry, capable of measuring weak enteromagnetic gradient signals and linearly converting them into analog voltage signals.

[0049] Furthermore, the gradient coil 21 includes a first coil and a second coil of the same size; wherein the first coil and the second coil are parallel and coaxially arranged. It is used to receive the enteric magnetic gradient signal amplified by the magnetic concentrator 1, and obtains the enteric magnetic gradient signal by subtracting the magnetic flux of the two coils, effectively eliminating geomagnetic interference. Its principle is as follows... Figure 3 As shown, when the dynamic enteromagnetic gradient signal and the geomagnetic signal pass through the gradient coil simultaneously, the magnetic flux Ф1 of the first coil is Ф intestine1 +Ф earth The magnetic flux of the second coil is Ф2=Ф intestine2 +Ф earth The final magnetotropic gradient signal of gradient coil 21 is Ф2-Ф1, at which point the geomagnetic interference is canceled out.

[0050] Compared to a conventional magnetometer, the gradient meter 2 configuration improves detection sensitivity while eliminating geomagnetic interference. The magnetic concentrator 1, positioned along the longitudinal axis, shields magnetic noise outside the sensitive direction and amplifies the enteromagnetic gradient signal in a directional manner. Through the gain of the magnetic concentrator 1, the enteromagnetism detection device can detect weak magnetic fields exceeding its sensitivity while maintaining a certain spatial resolution, thus improving the signal-to-noise ratio. The combination of the magnetic concentrator 1 and the gradient meter 2 ensures high sensitivity and high signal-to-noise ratio detection of weak enteromagnetism while eliminating geomagnetic interference and shielding magnetic noise outside the sensitive direction.

[0051] Specifically, the magnetic concentrator 1 is a specially designed structure, comprising: a magnetic concentrator body 11 and a shielding shell 12; the shielding shell 12 is a cylindrical structure with one end open and the other closed, which can shield magnetic noise outside the sensitive direction, and if configured with a multi-channel gradient meter, it can decouple the mutual interference between channels. The sidewall 121 of the cylindrical structure is made of a ferromagnetic material with high magnetic permeability, and the end face 122 is made of a non-magnetic plate that can pass through a magnetic field, used to connect the magnetic concentrator body 11, and has no effect on the magnetic circuit, serving only as a connector. The size of the shielding shell 12 is proportional to the size of the magnetic concentrator 1. The closed end of the shielding shell 12 faces the gradient meter 2 and is coaxially and closely arranged with the gradient coil 21 in the gradient meter 2, while the open end faces the target body; the magnetic concentrator body 11 is located inside the shielding shell 12 and is used to concentrate and amplify the magnetic field. Further, as... Figure 5 As shown, the magnetic concentrator body 11 is a solid structure made of a material with a relative permeability greater than 5000, comprising: a first body and a second body; wherein the first body is a frustum-shaped structure and the second body is a cylindrical structure; the first end face of the first body is connected to the second body, and the second end face of the first body faces the target body, serving as a magnetic flux collection end; wherein the area of ​​the second end face is larger than the area of ​​the first end face; one end of the second body is connected to the first body, and the other end is connected to end face 122, close to the gradient coil 21, serving as a magnetic flux release end; and the first body and the second body are coaxially arranged, and the magnetic concentrator body 11 and the gradient coil 21 are also coaxially arranged. Furthermore, the first body and the second body are integrally formed.

[0052] In this embodiment, since the diameter of the gradient coil 21 in the gradient meter 2 is 5mm, the diameter of the magnetic concentrator 1 should exceed 5mm to ensure more uniform magnetic field detection of the coil. Therefore, the diameter of the first main body bottom surface is set to d=150mm, the cone height h=150mm, and the diameter of the second main body column is set to... i =10mm, column height h i =150mm.

[0053] The magnetic concentrator 1 gathers and amplifies the enteric magnetic gradient signal before transmitting it to the gradient coil 21, thus amplifying the enteric magnetic gradient signal. The amplified enteric magnetic gradient signal is then transmitted to the SQUID module 22 via the gradient coil 21. Specifically, the amplification principle of the magnetic concentrator 1 is as follows: Figure 4 As shown, where Ф air and Ф m R and R0 represent the magnetic flux in the air and the magnetic flux through magnetic concentrator 1, respectively. air The magnetic reluctance of different branches in the equivalent circuit corresponds to Ф. m and Ф air By analyzing the magnetic reluctance of the air region, the magnetic flux entering the magnetic concentrator 1 can be indirectly reflected. The greater the magnetic reluctance of the air region, the greater the magnetic flux entering the magnetic concentrator 1. The magnetic concentrator 1 operates on the principle that its ferromagnetic structure can collect magnetic flux from a larger area and concentrate it into a smaller central region. Ideally, the main body of the magnetic concentrator 1 should be made of a soft magnetic material with low remanence, high relative permeability, and low relative loss factor. The magnetic field gain of the magnetic concentrator 1 increases with the increase of the relative permeability of the material. Considering that the magnetic field gain of the magnetic concentrator 1 should be sufficiently large, it is preferable to use a high-permeability material with a relative permeability greater than 5000. For this purpose, high-permeability materials such as ferrite or permalloy can be selected.

[0054] like Figure 6 As shown, magnetic signals of the same amplitude in the z and x directions were applied to the designed magnetic concentrator, and finite element simulations were performed on its magnetic field distribution. Using the magnetic field without the concentrator as a reference, the magnetic field amplitude with the concentrator was divided by the reference value to obtain the magnetic field enhancement factor. The resulting distribution of the enhancement factor of the magnetic concentrator for the z-direction magnetic signal is shown in the figure. Figure 6 As shown in 'a', the magnetic field enhancement factor of the gradient coil (as shown by the circle in the enlarged image) is 11.79. The enhancement factor distribution of the magnetic signal in the x-direction by the magnetic concentrator is as follows: Figure 6 As shown in b, the magnetic field enhancement factor of the gradient coil (as shown in the circle in the enlarged figure) is 0.07. This indicates that the magnetic amplifier designed in this embodiment is only sensitive to the enteromagnetic gradient signal in the z-direction, and has a larger enhancement factor for the signal in this direction, while having a smaller enhancement factor for signals in other directions, thus achieving directional amplification of the magnetic signal.

[0055] Furthermore, the conditioning circuit 3 includes an amplifier circuit and a low-pass filter circuit; wherein, the amplifier circuit is used to amplify the analog voltage signal, and the low-pass filter circuit is used to perform low-pass filtering on the amplified analog voltage signal to suppress high-frequency noise, thereby improving the signal-to-noise ratio of the magnetic field gradient signal.

[0056] Furthermore, the examination bed 5 can be made of non-magnetic materials such as copper, aluminum, fiberglass, or wood, and includes a bed frame and a bed board; the bed board and bed frame are slidably connected in both the longitudinal and transverse directions to achieve movement in the XY directions. That is, it slides along the x or y track under the drive of a motor, exposing the patient's abdomen below the magnetic concentrator, and moves horizontally stepwise relative to the magnetic concentrator, thereby performing a two-dimensional stepwise scan of the intestinal magnetic distribution in the abdomen.

[0057] By adjusting the movable bed board, the patient's position is changed, thereby altering the position of the detection probe on the patient's abdomen. The intestinal magnetic gradient signal, for example... Figure 2 As shown, the detected enteromagnetic gradient signal is a low-frequency signal that varies with time, and its signal strength is extremely weak, with an amplitude of approximately 10. -12 T. According to the standards established for each part of the intestine, its frequency domain signal will show abnormal frequency spikes. The spatial resolution of the enteromagnetism detection device can be changed by dividing the position coordinates of the magnetic concentrator 1. The smaller the coordinate interval, the higher the spatial resolution, but it cannot be smaller than the bottom diameter of the first main body in the magnetic concentrator 1 to avoid signal overlap.

[0058] When using the magnetoenterography (MEG) detection device in this embodiment, the gradiometer must first be calibrated to set its circuit operating point, sampling time, number of sampling points, sampling rate, and amplifier circuit gain. Furthermore, to ensure correct use of the device, it needs to be tested periodically using a simulated magnetic source. The testing method steps provided by this invention are as follows:

[0059] S1. Parameter settings: First, calibrate the SQUID gradient meter, set its circuit operating point, sampling time, number of sampling points, sampling rate, and amplifier circuit gain.

[0060] S2. Set up a simulated magnetic source: Fix the position of the enteromagnetic detection device on the movable non-magnetic examination bed, place a simulated intestinal signal source on it, set a standard 1pT magnetic field signal, start the enteromagnetic detection device, and record the voltage amplitude U1 displayed by the enteromagnetic detection device at this time.

[0061] S3. Diagnostic site scanning: Following the set trajectory, the position of the examination bed is changed to change the simulated intestinal site detected by the enteromagnetic detection device. Multiple fixed-point detections are performed on each intestinal site and the average is taken.

[0062] S4. Compare with standard cloud map: Observe the simulated magnetic field cloud map on the acquisition system and judge whether the equipment is operating correctly according to the set standard.

[0063] In summary, this embodiment provides a magnetoenterography detection device combining a highly directional magnetic concentrator and a gradiometer. It utilizes an ultra-high sensitivity SQUID gradiometer instead of a conventional magnetic field sensor to detect intestinal magnetic gradient signals, improving the accuracy of intestinal disease detection. Furthermore, by incorporating a specially designed highly directional magnetic concentrator, it shields magnetic noise outside the sensitive direction, focusing and amplifying the magnetic field signal. This not only eliminates geomagnetic interference but also shields magnetic noise outside the sensitive direction, and amplifies the intestinal magnetic gradient signal, thereby further improving the signal-to-noise ratio and sensitivity for detecting weak intestinal magnetic signals. This provides a new approach for the diagnosis of intestinal diseases.

[0064] Furthermore, it should be noted that in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. The terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or terminal device that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or terminal device. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or terminal device that includes said element.

[0065] Finally, it should be noted that the above description is merely a preferred embodiment of the present invention. It should be pointed out that although preferred embodiments of the present invention have been described, those skilled in the art, once they understand the basic inventive concept of the present invention, can make several improvements and modifications without departing from the principles described herein. These improvements and modifications should also be considered within the scope of protection of the present invention. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments as well as all changes and modifications falling within the scope of the embodiments of the present invention.

Claims

1. An intestinal magnetic map detection device combining a strong tropism magnetic concentrator and a gradiometer, characterized in that: include: Magnetic concentrator, gradiometer, conditioning circuit, data acquisition system and diagnostic bed; wherein, The magnetic concentrator is located above the diagnostic bed, the gradiometer is located above the magnetic concentrator, the gradiometer is electrically connected to the conditioning circuit, and the conditioning circuit is electrically connected to the data acquisition system; The diagnostic bed is made of non-magnetic material and is used to place the target body to be detected by intestinal magnetography; The magnetic concentrator is used to concentrate and amplify the magnetic gradient signal generated by the intestinal activity of the target body; the gradiometer is used to receive the amplified magnetic gradient signal and convert the received magnetic gradient signal into a corresponding analog voltage signal; the conditioning circuit is used to preprocess the analog voltage signal; the data acquisition system is used to convert the preprocessed analog voltage signal into a corresponding digital signal to complete intestinal magnetogram detection.

2. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 1, characterized in that: The magnetic concentrator comprises: a magnetic concentrator body and a shielding shell; The shielding shell is a cylindrical structure with one end open and the other end closed, the side wall of the cylindrical structure is made of a material with a magnetic permeability greater than 5000, and the end face of the cylindrical structure is made of a non-magnetic material; the shielding shell is used to shield magnetic noise in a preset direction; wherein the closed end of the shielding shell faces the gradiometer, and the open end of the shielding shell faces the target body; The magnetic concentrator body is located inside the shielding shell.

3. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 2, characterized in that: The magnetic concentrator body comprises: a first body and a second body; The first body is a truncated cone structure, and the second body is a cylindrical structure; the first end face of the first body is connected to the second body, and the second end face of the first body faces the target body, wherein the area of ​​the second end face is larger than the area of ​​the first end face; one end of the second body is connected to the first body, and the other end is connected to the top of the shielding shell, and the first body and the second body are coaxially arranged.

4. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 3 is characterized in that: The first body and the second body are integrally formed.

5. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 2, characterized in that: The magnetic concentrator body is made of a material with a magnetic permeability greater than 5000.

6. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 3, characterized in that: The gradiometer is a SQUID gradiometer.

7. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 6, characterized in that: The SQUID gradiometer comprises: a gradient coil, a SQUID module, a housing and a heat shield; The shell is made of non-magnetic Dewar material; the shell comprises an inner shell and an outer shell, a sandwich is formed between the inner shell and the outer shell, and a vacuum environment is formed in the sandwich; the shell is filled with liquid helium; The gradient coil, the SQUID module and the heat insulation plate are all located inside the shell; wherein the gradient coil is coupled to the SQUID module, the SQUID module is electrically connected to the conditioning circuit, and the heat insulation plate is arranged at one end of the shell to isolate the temperature outside the shell.

8. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 7, characterized in that: The gradient coil comprises: a first coil and a second coil of the same size; the first coil and the second coil are arranged in parallel and coaxially; and the magnetic concentrator body and the gradient coil are also arranged coaxially.

9. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 1, characterized in that: The conditioning circuit comprises: an amplifier circuit and a low-pass filter circuit; The amplifier circuit is used to amplify the analog voltage signal, and the low-pass filter circuit is used to perform low-pass filter processing on the amplified analog voltage signal.

10. The intestinal magnetogram detection device combining a strong tropism magnetic concentrator and a gradiometer as claimed in claim 1, characterized in that: The diagnostic bed comprises: a bed frame and a bed board; The bed board and the bed frame are slidably connected in both longitudinal and transverse directions to achieve movement in XY directions.

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