Portable urine analyzer

Abstract

The invention discloses a portable urine analyzer which comprises a reagent bin structure and a printing structure, and the reagent bin structure and the printing structure are packaged between an upper cover and a lower cover; the reagent bin structure comprises a sliding rail seat, a rack reagent bin, a reagent strip, a receiving plate, an LED lamp, a cover plate and a motor, the rack reagent bin is installed on the sliding rail seat and is in sliding fit with the sliding rail seat, the motor drives the rack reagent bin to move, the reagent strip is placed in the rack reagent bin, a light path seat is installed above the rack reagent bin, and the light path seat is connected with the light path seat. A green LED lamp and a red LED lamp are mounted on the light path seat, a receiving plate is arranged above the light path seat and receives light rays emitted from the reagent strip, and a cover plate covers the other end above the rack reagent bin. By reducing the structure of the reagent bin, the size of the whole urine analyzer is greatly reduced, and the urine analyzer is small and convenient to carry. A high-speed acquisition circuit is used for acquiring signals reflected by two light sources respectively, and the same effect as that of two light path acquisition circuits is achieved.

Description

Technical Field

[0001] The invention relates to a urine analyzer for a laboratory, in particular to a portable urine analyzer. Background Art

[0002] The urine analyzer determines the result based on the color change produced by the reaction of several specific components in the urine with the test strip. It outputs the test result after calculation by identifying the color change of the reaction reagent area.

[0003] The existing urine analyzer is relatively large in size, which is not convenient to carry and detect. At present, there are single-channel and multi-channel signal acquisition for optical path. Single-channel signal acquisition is mainly composed of photoelectric monitoring, conversion circuit, sampling and amplification circuit, and data processing module. Multi-channel signal acquisition requires the same resources for each signal acquisition, which increases the number of components, increases the volume, and is relatively costly. Summary of the invention

[0004] In order to solve the problem that urine analyzers are large in size and inconvenient to carry and test, the present invention provides a portable urine analyzer.

[0005] The present invention provides the following technical solutions: A portable urine analyzer comprises a reagent chamber structure and a printing structure, wherein the reagent chamber structure and the printing structure are encapsulated between an upper cover and a lower cover; The reagent bin structure comprises a slide rail seat, a rack reagent bin, a reagent strip, a receiving plate, an LED lamp, a cover plate and a motor. The rack reagent bin is mounted on the slide rail seat, the rack reagent bin is slidably matched with the slide rail seat, the motor drives the rack reagent bin to move, a reagent strip is placed in the rack reagent bin, an optical path seat is mounted on one end above the rack reagent bin, a green LED lamp and a red LED lamp are mounted on the optical path seat, a receiving plate is arranged above the optical path seat, the receiving plate receives the light emitted from the reagent strip, and the other end above the rack reagent bin is covered with a cover plate; A main control board is also installed between the upper cover and the lower cover. The main control board has a main control chip. The signal is transmitted to the red LED light and the green LED light through the traffic light channel control on the main control chip. The alternating flashing of the traffic light and the green LED light is controlled by a photodiode and hits the reagent strip.

[0006] Furthermore, the printing structure includes a paper bin cover, a printer, a paper bin box and a button. Printing paper is installed in the paper bin box, and the printer is arranged in the paper bin box and the paper bin cover.

[0007] Furthermore, a rack is provided on one side of the rack reagent compartment, and a long groove is provided on the other side of the rack reagent compartment for accommodating a reagent strip.

[0008] Furthermore, the shaft end of the motor is connected to a gear, and the motor drives the gear to mesh with the rack, driving the rack reagent compartment to move forward and backward.

[0009] Furthermore, a long track is provided in the slide rail seat, and a slide groove matching with the long track is provided at the bottom of the rack reagent compartment.

[0010] Furthermore, a display screen is installed in the upper cover, and the display screen is supported by a screen bracket.

[0011] Furthermore, a button and a battery are installed between the upper cover and the lower cover. The button is installed on the upper cover, and the lower side of the button is aligned with the main control board. The main control board and the battery are installed in the lower cover.

[0012] Furthermore, the red and green lights of the red LED lamp and the green LED lamp shine light on the reagent strip, which is reflected to the photodiode and converted into a weak electrical signal. The weak electrical signal is amplified and processed by the back stage and then the voltage signal is collected through a high-speed ADC. When the collection is completed, the data is analyzed and processed and saved; if not, it is fed back to the high-speed ADC.

[0013] Compared with the prior art, the present invention has the following beneficial effects: 1. By reducing the reagent compartment structure, the size of the entire urine analyzer is greatly reduced, making it a small and easy-to-carry instrument.

[0014] 2. The main control chip is used to control the red and green lights to flash alternately, and the alternating flashing signals are transmitted to the amplifier circuit, eliminating the need for a signal amplification and acquisition circuit, reducing the number of components, reducing the use and production costs, and increasing system stability. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is the appearance diagram of the present invention.

[0016] Figure 2 It is an exploded view of the present invention.

[0017] Figure 3 It is a structural schematic diagram of the reagent chamber structure of the present invention.

[0018] Figure 4 This is an enlarged schematic diagram of the motor-driven rack reagent compartment of the present invention.

[0019] Figure 5 It is a schematic diagram of the present invention.

[0020] Figure 6 This is the pin diagram of the main control chip (STM32F429IGT6) of the present invention.

[0021] In the figure: 1. upper cover; 2. paper compartment cover; 3. screen bracket; 4. display screen; 5. receiving board; 6. green LED light; 7. red LED light; 8. optical path seat; 9. main control board; 10. printer; 11. printing paper; 12. paper compartment box; 13. button; 14. cover plate; 15. rack reagent compartment; 151. rack; 152. long groove; 153. slide groove; 16. motor; 161. gear; 17. slide rail seat; 171. long rail; 18. battery; 19. lower cover; 20. reagent strip. Implementation

[0022] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] See also Figure 1 The portable urine analyzer of the present invention comprises a reagent chamber structure and a printing structure, wherein the reagent chamber structure and the printing structure are packaged between an upper cover 1 and a lower cover 19. The reagent bin structure includes a slide rail seat 17, a rack reagent bin 15, a reagent strip 20, a receiving plate 5, an LED lamp, a cover plate 14 and a motor 16. The rack reagent bin 15 is installed on the slide rail seat 17. The rack reagent bin 15 and the slide rail seat 17 are slidably matched. The motor 16 drives the rack reagent bin 15 to move so that the rack reagent bin 15 slides normally on the slide rail seat 17. The reagent strip 20 is placed in the rack reagent bin 15. An optical path seat 8 is installed at one end above the rack reagent bin 15. A green LED lamp 6 and a red LED lamp 7 are installed on the optical path seat 8. A receiving plate 5 is arranged above the optical path seat 8. The receiving plate 5 receives the light emitted from the reagent strip 20. The other end above the rack reagent bin 15 is covered with a cover plate 14. The cover plate 14 prevents external light from interfering with the test.

[0024] A rack 151 is disposed on one side of the rack reagent compartment 15 , and a long groove 152 is disposed on the other side of the rack reagent compartment 15 for accommodating the reagent strip 20 .

[0025] The shaft end of the motor 16 is connected to the gear 161 , and the motor 16 drives the gear 161 to mesh with the rack 151 , thereby driving the rack reagent compartment 15 to move forward and backward.

[0026] A long rail 171 is provided in the rail seat 17 , and a slide groove 153 matching with the long rail 171 is provided at the bottom of the rack reagent compartment 15 .

[0027] After the reagent strip 20 is fully in contact with urine, a reaction occurs, and the reagent strip 20 is used to detect the content of each component in urine.

[0028] A display screen 4 is installed in the upper cover 1 , and the display screen 4 is supported by a screen bracket 3 .

[0029] The printing structure includes a paper bin cover 2, a printer 10, a paper bin box 12 and a button 13. Printing paper 11 is installed in the paper bin box 12, and the printer 10 is arranged in the paper bin box 12 and the paper bin cover 2.

[0030] A main control board 9 , a button 13 and a battery 18 are also installed between the upper cover 1 and the lower cover 19 . The button 13 is installed on the upper cover 1 , with the lower side of the button 13 aligned with the main control board 9 . The main control board 9 and the battery 18 are installed in the lower cover 19 .

[0031] The main control board 9 is provided with a main control chip, and the main control chip adopts STM32F429IGT6.

[0032] The signal is transmitted to the red LED light 7 and the green LED light 6 through the traffic light channel control on the main control chip, and the alternating flashing of the traffic lights is controlled by a photodiode to hit the reagent strip 20. The alternating flashing of the traffic lights replaces the use of two centralized procurement circuits, thereby achieving the advantages of simplifying the circuit, improving stability, and reducing costs.

[0033] Main control chip data processing flow: 1. Start; 2. Is the acquisition finished? If not, the I / O outputs high and low level signals; if yes, the acquisition is finished and the I / O output is turned off; 3. Input the signal into the traffic light control circuit and transmit it to the red LED light 7 and the green LED light 6; 4. A photodiode is used to control the flashing of the traffic light in the traffic light control circuit, and then the signal is amplified by the amplifier circuit and sent to the high-speed ADC; 5. The high-speed ADC collects the voltage signal. If yes, the collection ends, and the data is analyzed and processed, saved, and ended; if not, it is fed back to the high-speed ADC.

[0034] The present invention uses a high-speed acquisition circuit to respectively collect the signals reflected by the two light sources, and achieves the same effect as the two-path light path acquisition system through data processing and analysis, thereby simplifying the circuit part design and improving the stability of the overall system.

[0035] The red / green lights flash alternately, and part of the integrated operational amplifier can be used as a constant current source for the light, and the other part can be used as a voltage amplifier. The red / green light shines light on the reagent strip, which is reflected to the photodiode and converted into a weak electrical signal. The post-stage amplifies the weak signal and sends the signal to the STM32 via a high-speed analog / digital converter ADC. The STM32 can control the red / green light switch and the switching time, so as to use one signal acquisition circuit to collect and convert the red / green light signals.

[0036] Working principle: There are reactants on the test strip, which will change color after reacting with the components in urine. The LED light is on the test strip, because the color changes, and the content of the test cost in the urine is different, the depth of the color change is different, the reflectivity is also different, and the received light intensity will be different, and the content of each component in the urine will be measured in turn.

[0037] Performance verification using the urine analysis instrument of the present invention: 1. Accuracy Experimental steps: Take the test strips to test the standard solutions of each concentration level for all 14 test items; measure each concentration level 3 times; record the test results; calculate the difference in magnitude between the test results and the marked concentration of the reference solution.

[0038] Table 1 Test strips for standard solutions at various concentration levels for 14 test items

[0039] The result shall not differ from the labeled value of the corresponding reference solution by more than one order of magnitude in the same direction. No positive result shall appear in the negative standard solution, and no negative result shall appear in the positive standard solution.

[0040] 2. Stability Take a test strip and place it on the stage; click test and bring the color card into the stage to start scanning; wait and record 10 measurement results; record 3 sets of reflectance measurement results in total; calculate the coefficient of variation (CV, %) of all reflectances; CV=SD / M*100%, CV – coefficient of variation; SD – standard deviation of 10 measurements; M is the arithmetic mean of 10 measurement results.

[0041] Table 2 Test table of sample strips with certain reflectivity after 0h of preheating

[0042] Table 3 Test table of sample strips with certain reflectivity 4 hours after preheating

[0043] Table 4 Test table of sample strips with certain reflectivity after 8 hours of preheating

[0044] After calculation, the CV in the above table is = 0.1%.

[0045] After the machine is preheated for 0h, 4h, and 8h, the sample strips with a certain reflectivity are tested repeatedly 10 times, and the coefficient of variation (CV,%) of all reflectivities is calculated to meet the requirement of ≤1.0.

[0046] Stability comparison analysis: using the Aikon U60Mini instrument as a comparison test stability Table 5 is the test table of sample strips with certain reflectivity after 0h of preheating of the Aikon U60Mini instrument.

[0047] Table 6 is the test table of sample strips with certain reflectivity after 4 hours of preheating of the ICON U60Mini instrument.

[0048] Table 7 is the test table of sample strips with certain reflectivity after the ICON U60Mini instrument was turned on and preheated for 8 hours

[0049] After calculation, the CV of the Ikon U60Mini instrument in the above table is 0.53%, and the CV of the portable urine analyzer is 0.1%. Since the smaller the coefficient of variation (CV,%), the lower the degree of dispersion, the performance of the portable urine analyzer is better than that of the Ikon U60Mini instrument.

[0050] Verification summary: The test performance of the instrument of the present invention can meet the performance requirements of industry standards.

[0051] The present invention has the following advantages: 1. By reducing the reagent compartment structure, the size of the entire urine analyzer is greatly reduced, making it a small and easy-to-carry instrument with a total size of 178*87*46mm.

[0052] 2. Through a high-speed acquisition circuit, two LED lights flash alternately to replace the problem of using two acquisition circuits, effectively simplifying the circuit and improving stability to achieve optical path acquisition.

[0053] 3. The main control chip is used to control the red and green lights to flash alternately, and the alternating flashing signals are transmitted to the amplifier circuit through the photodiode, which saves a signal amplification and collection circuit, reduces the number of components, reduces the use and production costs, and increases system stability.

[0054] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. Portable urine analyzer, characterized in that: It comprises a reagent chamber structure and a printing structure, wherein the reagent chamber structure and the printing structure are encapsulated between an upper cover (1) and a lower cover (19); The reagent chamber structure comprises a slide rail seat (17), a rack reagent chamber (15), a reagent strip (20), a receiving plate (5), an LED lamp, a cover plate (14) and a motor (16); the rack reagent chamber (15) is mounted on the slide rail seat (17); the rack reagent chamber (15) and the slide rail seat (17) are slidably matched; the motor (16) drives the rack reagent chamber (15) to move; a reagent strip (20) is placed in the rack reagent chamber (15); an optical path seat (8) is mounted on one end above the rack reagent chamber (15); a green LED lamp (6) and a red LED lamp (7) are mounted on the optical path seat (8); a receiving plate (5) is arranged above the optical path seat (8); the receiving plate (5) receives light emitted from the reagent strip (20); and the other end above the rack reagent chamber (15) is covered with a cover plate (14); A main control board (9) is also installed between the upper cover (1) and the lower cover (19). The main control board (9) has a main control chip. The signal is transmitted to the red LED light (7) and the green LED light (6) through the traffic light channel control on the main control chip. The red and green lights are controlled to flash alternately on the reagent strip (20) through a photodiode.

2. The portable urine analyzer according to claim 1, characterized in that: The printing structure comprises a paper bin cover (2), a printer (10), a paper bin box (12) and a button (13); printing paper (11) is installed in the paper bin box (12); and the printer (10) is arranged in the paper bin box (12) and the paper bin cover (2).

3. The portable urine analyzer according to claim 1, characterized in that: A rack (151) is provided on one side of the rack reagent compartment (15), and a long groove (152) is provided on the other side of the rack reagent compartment (15) for accommodating a reagent strip (20).

4. The portable urine analyzer according to claim 1, characterized in that: The shaft end of the motor (16) is connected to a gear (161), and the motor (16) drives the gear (161) to mesh with the rack (151), thereby driving the rack reagent compartment (15) to move forward and backward.

5. The portable urine analyzer according to claim 1, characterized in that: The slide rail seat (17) has a long rail (171) in it, and the bottom of the rack reagent compartment (15) is provided with a slide groove (153) that matches the long rail (171).

6. The portable urine analyzer according to claim 1, characterized in that: A display screen (4) is installed inside the upper cover (1), and the display screen (4) is supported by a screen bracket (3).

7. The portable urine analyzer according to claim 1, characterized in that: A button (13) and a battery (18) are also installed between the upper cover (1) and the lower cover (19); the button (13) is installed on the upper cover (1), the lower side of the button (13) is aligned with the main control board (9), and the main control board (9) and the battery (18) are installed in the lower cover (19).

8. The portable urine analyzer according to claim 1, characterized in that: The red and green lights of the red LED lamp (7) and the green LED lamp (6) shine light on the reagent strip, which is reflected to the photodiode and converted into a weak electrical signal. The weak electrical signal is amplified and processed in the back stage, and then a voltage signal is collected via a high-speed ADC. After the collection is completed, data analysis and processing are performed and stored. If not, feedback is given to the high speed ADC.

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