Non-iodine preparation dairy cow nipple medicated bath liquid and preparation method thereof

Abstract

The invention relates to the field of dairy cow nipple medicated bath liquid, in particular to non-iodine preparation dairy cow nipple medicated bath liquid and a preparation method thereof, and the non-iodine preparation dairy cow nipple medicated bath liquid comprises the following medicines: purified water, biguanide fungicide, a skin care agent, a thickening agent, alcohols, a film-forming agent, a pH regulator, pigment and a nonionic surfactant. The problems that a traditional iodine-containing medicated bath liquid is unstable under illumination and high temperature and has a short bactericidal effect are solved, and the dairy cow nipple medicated bath liquid adopts the biguanide bactericide for sterilization, is efficient, broad-spectrum, lasting in effect, safe, free of side effects, not prone to drug resistance generation, appropriate in viscosity and free of dripping within 30 s, forms a protective film on dairy cow nipples within 10 min, and has a good application prospect. The invasion of microorganisms is effectively prevented; the waste amount of the medicated bath liquid is reduced, and the use cost of the medicated bath liquid is reduced.

Description

Technical Field

[0001] The invention relates to the field of dairy cow teat dipping solution, in particular to a non-iodine dairy cow teat dipping solution and a preparation method thereof. Background Art

[0002] Cow mastitis is caused by infection with a variety of pathogenic microorganisms, especially Staphylococcus aureus, Escherichia coli, Streptococcus, Mycoplasma and other infections are more common. Cow mastitis is one of the most common diseases in dairy cow production and causes the greatest economic losses. People who eat milk produced by cows with mastitis will suffer from symptoms such as diarrhea, vomiting and fever. Therefore, it is necessary to strengthen the prevention and treatment of cow mastitis, which is of great significance in production practice and food safety.

[0003] Symptoms of mastitis in dairy cows include floccules in milk, abnormal odor, severe swelling and pain in the udder, loss of appetite, and rapid decline in milk production. The causes are mostly mechanical stimulation, invasion of pathogenic microorganisms, and chemical and physical damage. Mechanical stimulation is mostly caused by milking equipment. There are more than 150 known pathogenic microorganisms, including streptococci, bacilli, mycoplasmas, fungi, yeasts, and viruses. Most of them are caused by bacterial infection, mainly by Gram-positive bacteria (such as Streptococcus agalactiae and Staphylococcus aureus). Gram-negative bacteria (Escherichia coli) are also common in large-scale farming. The prevention and control measures usually taken include improving milking hygiene, creating good sanitary conditions, and enhancing the immunity of dairy cows. Improving milking hygiene is the most important aspect. At present, medicated dipping of dairy cows' nipples before and after milking is the most common and effective method.

[0004] There are many kinds of traditional medicated dips. The most widely used dairy cow nipple medicated dips are mainly iodine disinfectants. Such disinfectants are generally composed of povidone iodine, glycerol, ethanol and a film-forming agent or polyvinyl pyrrolidone, iodine, potassium iodide (sodium iodide), glycerol, ethanol and a thickener. They can form a protective film on the dairy cow nipples and have a certain protective effect on the nipples. However, they have the following defects: (1) The moisturizing effect of glycerol is easily affected by the humidity of the environment. When the relative humidity of the environment is too low, the effect of retaining water molecules will decrease; (2) Iodine preparations have a slight and short-term irritation to the local wound mucosa of the dairy cow nipples, are unstable under light and high temperature, and have a short-term bactericidal effect; (3) The cost of iodine preparation dairy cow nipple medicated dips is relatively high;

[0005] Therefore, in view of the fact that the moisturizing effect of glycerin is easily affected by the environmental humidity, and that iodine preparations have a slight and short-term irritating effect on the local wound mucosa of the cow nipple, and the high cost, a non-iodine preparation cow nipple medicated dip and its preparation method can be designed. Summary of the invention

[0006] In order to overcome the problem that the moisturizing effect of glycerol is easily affected by environmental humidity, and iodine preparations have a slight and short-term irritating effect on the local injured mucosa of the cow's nipples, and the cost is relatively high.

[0007] The technical solution of the present invention is: a non-iodine preparation dairy cow teat dip, comprising the following drugs: purified water, biguanide fungicide, skin care agent, thickener, alcohol, film former, pH regulator, pigment and non-ionic surfactant, in the following proportions by weight:

[0008] Purified water: 30 to 50 parts;

[0009] Biguanide fungicide: 0.1 to 0.6 parts;

[0010] Skin care agent: 5 to 20 parts;

[0011] Thickener: 0.1 to 0.3 parts;

[0012] Alcohols: 5 to 60 parts;

[0013] Film-forming agent: 0.5 to 5 parts;

[0014] pH adjuster: 0.01 to 0.5 parts;

[0015] Pigment: 0.01 to 0.05 parts;

[0016] Nonionic surfactant: 0.1 to 0.5 parts.

[0017] Preferably, the biguanide bactericidal agent is one of chlorhexidine acetate, chlorhexidine gluconate and polyhexamethylene biguanide.

[0018] Preferably, the skin care agent is one of glycerol and sorbitol or a mixed solution of the two.

[0019] Preferably, the thickener is one of sodium carboxymethyl cellulose, curdlan, linseed gum and gum arabic.

[0020] Preferably, the alcohol is ethanol.

[0021] Preferably, the film-forming agent is one of polyvinyl alcohol and povidone K30.

[0022] Preferably, the pH adjuster is one of sodium hydroxide, triethanolamine, disodium hydrogen phosphate, sodium citrate or sodium tripolyphosphate.

[0023] Preferably, the pigment is bright blue or fruit green.

[0024] Preferably, the nonionic surfactant is one of alkyl glycoside, fatty alcohol polyoxyethylene ether and polyoxyethylene sorbitan fatty acid ester.

[0025] A method for preparing a non-iodine preparation dairy cow teat dip, comprising the above-mentioned non-iodine preparation dairy cow teat dip, and the steps are as follows:

[0026] Step 1: Take purified water by weight, heat it to 40-50°C, keep the purified water temperature unchanged, add thickener, skin care agent and pigment by weight in sequence, heat and stir until dissolved, and obtain a standby solution A;

[0027] Step 2: Take a film-forming agent by weight, add it to an alcohol solution by weight, and after it is evenly dispersed, take a purified water by weight and add it thereto, and stir until the film-forming agent is completely dissolved to obtain a standby solution B;

[0028] Step 3: Take purified water by weight, add pH adjuster by weight, and stir until the pH adjuster is completely dissolved to obtain a standby solution C;

[0029] Step 4: add the reserve solution A, the biguanide fungicide, the reserve solution B, the reserve solution C and the non-ionic surfactant in parts by weight in sequence, stir while adding, and finally circulate and stir for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0030] Beneficial effects of the present invention:

[0031] The invention solves the problem that the traditional iodine-containing medicinal bath solution is unstable under light and high temperature and has a short bactericidal effect. The dairy cow teat medicinal bath solution of the invention uses a biguanide bactericide for bactericidal effect, has high efficiency and broad spectrum, lasting effect, is safe and has no side effects, is not easy to produce drug resistance, has appropriate viscosity, does not drip within 30 seconds, forms a protective film on the dairy cow teat within 10 minutes, and effectively prevents the invasion of microorganisms; reduces the waste of medicinal bath solution and reduces the use cost of the medicinal bath solution. DETAILED DESCRIPTION

[0032] The present invention will be further described below in conjunction with the embodiments.

[0033] Example 1

[0034] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0035] Purified water: 30 parts;

[0036] Biguanide fungicide: 0.2 parts;

[0037] Skin care agent: 2 parts;

[0038] Thickener: 0.2 parts;

[0039] Alcohols: 30 parts;

[0040] Film former: 0.5 parts;

[0041] pH regulator: 0.1 part;

[0042] Pigment: 0.1 part;

[0043] Nonionic surfactant: 0.1 part.

[0044] Among them, the biguanide fungicide of the bath liquid is chlorhexidine acetate; the skin care agent of the bath liquid is glycerin; the thickener of the bath liquid is sodium carboxymethyl cellulose; the alcohol of the bath liquid is ethanol; the film-forming agent of the bath liquid is povidone K30; the pH value regulator of the bath liquid is sodium tripolyphosphate; the pigment of the bath liquid is fruit green; and the non-ionic surfactant of the bath liquid is fatty alcohol polyoxyethylene ether.

[0045] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0046] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerin and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0047] Step 2: Take povidone K30 by weight, add it to the ethanol solution by weight, disperse it evenly, then take water by weight and add it thereto, stir until the povidone K30 is completely dissolved, and obtain a standby solution B;

[0048] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0049] Step 4: sequentially add the reserve solution A and parts by weight of chlorhexidine acetate, reserve solution C, and fatty alcohol polyoxyethylene ether into the reserve solution B, stirring while adding, and finally circulating stirring for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0050] Example 2

[0051] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0052] Purified water: 20 parts;

[0053] Biguanide fungicide: 0.5 parts;

[0054] Skin care agent: 14 parts;

[0055] Thickener: 0.2 parts;

[0056] Alcohols: 60 parts;

[0057] Film former: 0.2 parts;

[0058] pH regulator: 0.01 parts;

[0059] Pigment: 0.1 part;

[0060] Nonionic surfactant: 0.1 part.

[0061] Among them, the biguanide fungicide of the bath liquid is chlorhexidine gluconate; the skin care agent of the bath liquid is glycerin; the thickener of the bath liquid is sodium carboxymethyl cellulose; the alcohol of the bath liquid is ethanol; the film-forming agent of the bath liquid is povidone K30; the pH value regulator of the bath liquid is sodium tripolyphosphate; the pigment of the bath liquid is fruit green; and the non-ionic surfactant of the bath liquid is fatty alcohol polyoxyethylene ether.

[0062] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0063] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add carboxymethyl cellulose, glycerin and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0064] Step 2: Take povidone K30 by weight, add it to the ethanol solution by weight, disperse it evenly, then take water by weight and add it thereto, stir until the povidone K30 is completely dissolved, and obtain a standby solution B;

[0065] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0066] Step 4: Mix the biguanide fungicide chlorhexidine gluconate and the remaining weight parts of ethanol, add the reserve solution A, the reserve solution C, and the fatty alcohol polyoxyethylene ether into the reserve solution B in sequence, stir while adding, and finally circulate and stir for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0067] Example 3

[0068] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0069] Purified water: 20 parts;

[0070] Biguanide fungicide: 0.5 parts;

[0071] Skin care agent: 5 parts;

[0072] Thickener: 0.2 parts;

[0073] Alcohols: 5 parts;

[0074] Film former: 0.2 parts;

[0075] pH regulator: 0.1 part;

[0076] Pigment: 0.1 part;

[0077] Nonionic surfactant: 0.1 part.

[0078] Among them, the biguanide fungicide of the bath liquid is polyhexamethylene biguanide; the skin care agent of the bath liquid is glycerin; the thickener of the bath liquid is sodium carboxymethyl cellulose; the alcohol of the bath liquid is ethanol; the film-forming agent of the bath liquid is povidone K30; the pH value regulator of the bath liquid is sodium tripolyphosphate; the pigment of the bath liquid is fruit green; and the non-ionic surfactant of the bath liquid is fatty alcohol polyoxyethylene ether.

[0079] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0080] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add carboxymethyl cellulose, glycerin and brilliant blue pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0081] Step 2: Take povidone K30 by weight, add it to the ethanol solution by weight, disperse it evenly, then take water by weight and add it thereto, stir until the povidone K30 is completely dissolved, and obtain a standby solution B;

[0082] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0083] Step 4: sequentially add the reserve solution A and weight portions of polyhexamethylene biguanide, reserve solution C, and fatty alcohol polyoxyethylene ether into the reserve solution B, stirring while adding, and finally circulating stirring for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0084] Example 4

[0085] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0086] Purified water: 30 parts;

[0087] Biguanide fungicide: 0.2 parts;

[0088] Skin care agent: 2 parts;

[0089] Thickener: 0.4 parts;

[0090] Alcohols: 30 parts;

[0091] Film former: 0.5 parts;

[0092] pH regulator: 0.1 part;

[0093] Pigment: 0.1 part;

[0094] Nonionic surfactant: 0.1 part.

[0095] Among them, the biguanide fungicide of the medicinal bath liquid is chlorhexidine acetate; the skin care agent of the medicinal bath liquid is glycerin; the thickener of the medicinal bath liquid is sodium carboxymethyl cellulose; the alcohol of the medicinal bath liquid is ethanol; the film-forming agent of the medicinal bath liquid is polyvinyl alcohol (PVA); the pH value regulator of the medicinal bath liquid is sodium tripolyphosphate; the pigment of the medicinal bath liquid is fruit green; and the non-ionic surfactant of the medicinal bath liquid is fatty alcohol polyoxyethylene ether.

[0096] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0097] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerin and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0098] Step 2: Take polyvinyl alcohol (PVA) by weight, add it to the ethanol solution by weight, and after it is evenly dispersed, take water by weight and add it thereto, and stir until the polyvinyl alcohol is completely dissolved to obtain a standby solution B;

[0099] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0100] Step 4: sequentially add the reserve solution A and parts by weight of chlorhexidine acetate, reserve solution C, and fatty alcohol polyoxyethylene ether into the reserve solution B, stirring while adding, and finally circulating stirring for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0101] Example 5

[0102] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0103] Purified water: 20 parts;

[0104] Biguanide fungicide: 0.5 parts;

[0105] Skin care agent: 14 parts;

[0106] Thickener: 0.4 parts;

[0107] Alcohols: 60 parts;

[0108] Film former: 0.2 parts;

[0109] pH regulator: 0.01 parts;

[0110] Pigment: 0.1 part;

[0111] Nonionic surfactant: 0.1 part.

[0112] Among them, the biguanide fungicide of the bath liquid is chlorhexidine gluconate; the skin care agent of the bath liquid is glycerin; the thickener of the bath liquid is sodium carboxymethyl cellulose; the alcohol of the bath liquid is ethanol; the film-forming agent of the bath liquid is polyvinyl alcohol (PVA); the pH value regulator of the bath liquid is sodium tripolyphosphate; the pigment of the bath liquid is fruit green; and the non-ionic surfactant of the bath liquid is fatty alcohol polyoxyethylene ether.

[0113] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0114] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerin and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0115] Step 2: Take polyvinyl alcohol (PVA) by weight, add it to the ethanol solution by weight, and after it is evenly dispersed, take water by weight and add it thereto, and stir until the polyvinyl alcohol is completely dissolved to obtain a standby solution B;

[0116] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0117] The fourth step: mixing the biguanide fungicide chlorhexidine gluconate and the remaining weight parts of ethanol, adding the reserve solution A, the reserve solution C, and the fatty alcohol polyoxyethylene ether into the reserve solution B in sequence, stirring while adding, and finally circulating stirring for 30 minutes to obtain the non-iodine preparation and non-drip film-forming cow teat dipping solution.

[0118] Example 6

[0119] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0120] Purified water: 20 parts;

[0121] Biguanide fungicide: 0.5 parts;

[0122] Skin care agent: 5 parts;

[0123] Thickener: 0.4 parts;

[0124] Alcohols: 5 parts;

[0125] Film former: 0.2 parts;

[0126] pH regulator: 0.1 part;

[0127] Pigment: 0.1 part;

[0128] Nonionic surfactant: 0.1 part.

[0129] Among them, the biguanide fungicide of the bath liquid is polyhexamethylene biguanide; the skin care agent of the bath liquid is glycerin; the thickener of the bath liquid is sodium carboxymethyl cellulose; the alcohol of the bath liquid is ethanol; the film-forming agent of the bath liquid is polyvinyl alcohol (PVA); the pH value regulator of the bath liquid is sodium tripolyphosphate; the pigment of the bath liquid is fruit green; and the non-ionic surfactant of the bath liquid is fatty alcohol polyoxyethylene ether.

[0130] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0131] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerin and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0132] Step 2: Take polyvinyl alcohol (PVA) by weight, add it to the ethanol solution by weight, and after it is evenly dispersed, take water by weight and add it thereto, and stir until the polyvinyl alcohol is completely dissolved to obtain a standby solution B;

[0133] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0134] Step 4: sequentially add the reserve solution A and weight portions of polyhexamethylene biguanide, reserve solution C, and fatty alcohol polyoxyethylene ether into the reserve solution B, stirring while adding, and finally circulating stirring for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0135] Example 7

[0136] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0137] Purified water: 30 parts;

[0138] Biguanide fungicide: 0.2 parts;

[0139] Skin care agent: 4 parts;

[0140] Thickener: 0.4 parts;

[0141] Alcohols: 30 parts;

[0142] Film former: 0.5 parts;

[0143] pH regulator: 0.1 part;

[0144] Pigment: 0.1 part;

[0145] Nonionic surfactant: 0.1 part.

[0146] Among them, the biguanide fungicide of the medicinal bath liquid is chlorhexidine acetate; the skin care agent of the medicinal bath liquid is glycerol: sorbitol (3:1); the thickener of the medicinal bath liquid is sodium carboxymethyl cellulose; the alcohol of the medicinal bath liquid is ethanol; the film-forming agent of the medicinal bath liquid is polyvinyl alcohol (PVA); the pH value regulator of the medicinal bath liquid is sodium tripolyphosphate; the pigment of the medicinal bath liquid is fruit green; and the non-ionic surfactant of the medicinal bath liquid is fatty alcohol polyoxyethylene ether.

[0147] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0148] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerol: sorbitol (3:1) and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0149] Step 2: Take polyvinyl alcohol (PVA) by weight, add it to the ethanol solution by weight, and after it is evenly dispersed, take water by weight and add it thereto, and stir until the polyvinyl alcohol is completely dissolved to obtain a standby solution B;

[0150] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0151] Step 4: sequentially add the reserve solution A and weight portions of polyhexamethylene biguanide, reserve solution C, and fatty alcohol polyoxyethylene ether into the reserve solution B, stirring while adding, and finally circulating stirring for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0152] Example 8

[0153] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0154] Purified water: 20 parts;

[0155] Biguanide fungicide: 0.5 parts;

[0156] Skin care agent: 14 parts;

[0157] Thickener: 0.4 parts;

[0158] Alcohols: 60 parts;

[0159] Film former: 0.2 parts;

[0160] pH regulator: 0.01 parts;

[0161] Pigment: 0.1 part;

[0162] Nonionic surfactant: 0.1 part.

[0163] Among them, the biguanide fungicide of the medicinal bath liquid is chlorhexidine gluconate; the skin care agent of the medicinal bath liquid is glycerol: sorbitol (3:1); the thickener of the medicinal bath liquid is sodium carboxymethyl cellulose; the alcohol of the medicinal bath liquid is ethanol; the film-forming agent of the medicinal bath liquid is polyvinyl alcohol (PVA); the pH value regulator of the medicinal bath liquid is sodium tripolyphosphate; the pigment of the medicinal bath liquid is fruit green; and the non-ionic surfactant of the medicinal bath liquid is fatty alcohol polyoxyethylene ether.

[0164] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0165] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerol: sorbitol (3:1) and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0166] Step 2: Take polyvinyl alcohol (PVA) by weight, add it to the ethanol solution by weight, and after it is evenly dispersed, take water by weight and add it thereto, and stir until the polyvinyl alcohol is completely dissolved to obtain a standby solution B;

[0167] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0168] Step 4: Mix the biguanide fungicide chlorhexidine gluconate and the remaining weight parts of ethanol, add the reserve solution A, the reserve solution C, and the fatty alcohol polyoxyethylene ether into the reserve solution B in sequence, stir while adding, and finally circulate and stir for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

[0169] Example 9

[0170] The present invention provides an embodiment: a non-iodine preparation dairy cow nipple medicated dip, which is composed of the following raw materials in parts by weight:

[0171] Purified water: 20 parts;

[0172] Biguanide fungicide: 0.5 parts;

[0173] Skin care agent: 5 parts;

[0174] Thickener: 0.4 parts;

[0175] Alcohols: 5 parts;

[0176] Film former: 0.2 parts;

[0177] pH regulator: 0.1 part;

[0178] Pigment: 0.1 part;

[0179] Nonionic surfactant: 0.1 part.

[0180] Among them, the biguanide fungicide of the medicinal bath liquid is polyhexamethylene biguanide; the skin care agent of the medicinal bath liquid is glycerol: sorbitol (3:1); the thickener of the medicinal bath liquid is sodium carboxymethyl cellulose; the alcohol of the medicinal bath liquid is ethanol; the film-forming agent of the medicinal bath liquid is polyvinyl alcohol (PVA); the pH value regulator of the medicinal bath liquid is sodium tripolyphosphate; the pigment of the medicinal bath liquid is fruit green; and the non-ionic surfactant of the medicinal bath liquid is fatty alcohol polyoxyethylene ether.

[0181] A method for preparing a non-iodine preparation dairy cow teat dipping solution, comprising the following steps:

[0182] Step 1: Take water by weight, heat it to 45°C, keep the water temperature constant, then add sodium carboxymethyl cellulose, glycerol: sorbitol (3:1) and fruit green pigment by weight in sequence, stir until dissolved, and obtain a standby solution A;

[0183] Step 2: Take polyvinyl alcohol (PVA) by weight, add it to the ethanol solution by weight, and after it is evenly dispersed, take water by weight and add it thereto, and stir until the polyvinyl alcohol is completely dissolved to obtain a standby solution B;

[0184] Step 3: Take water by weight, add sodium tripolyphosphate by weight, and stir until the sodium tripolyphosphate is completely dissolved to obtain a standby solution C;

[0185] Step 4: sequentially add the reserve solution A and weight portions of polyhexamethylene biguanide, reserve solution C, and fatty alcohol polyoxyethylene ether into the reserve solution B, stirring while adding, and finally circulating stirring for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.

Claims

1. A non-iodine preparation dairy cow teat dip, characterized in that: The following drugs are included: purified water, biguanide bactericide, skin care agent, thickener, alcohol, film former, pH adjuster, pigment and non-ionic surfactant, in the following proportions by weight: Purified water: 30 to 50 parts; Biguanide fungicide: 0.1 to 0.6 parts; Skin care agent: 5 to 20 parts; Thickener: 0.1 to 0.3 parts; Alcohols: 5 to 60 parts; Film-forming agent: 0.5 to 5 parts; pH adjuster: 0.01 to 0.5 parts; Pigment: 0.01 to 0.05 parts; Nonionic surfactant: 0.1 to 0.5 parts.

2. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The biguanide fungicide is one of chlorhexidine acetate, chlorhexidine gluconate, and polyhexamethylene biguanide.

3. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The skin care agent adopts one of glycerin and sorbitol or a mixed solution of the two.

4. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The thickener is one of sodium carboxymethyl cellulose, curdlan, linseed gum and gum arabic.

5. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The alcohol is ethanol.

6. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The film-forming agent is one of polyvinyl alcohol and povidone K30.

7. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The pH value adjuster is one of sodium hydroxide, triethanolamine, disodium hydrogen phosphate, sodium citrate or sodium tripolyphosphate.

8. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The pigment is either bright blue or fruit green.

9. The non-iodine preparation dairy cow teat dipping solution according to claim 1, characterized in that: The nonionic surfactant is one of alkyl glycoside, fatty alcohol polyoxyethylene ether and polyoxyethylene sorbitan fatty acid ester.

10. A method for preparing a non-iodine preparation dairy cow teat dipping solution, characterized in that The method comprises the following steps: Step 1: Take purified water by weight, heat it to 40-50°C, keep the purified water temperature unchanged, add thickener, skin care agent and pigment by weight in sequence, heat and stir until dissolved, and obtain a standby solution A; Step 2: Take a film-forming agent by weight, add it to an alcohol solution by weight, and after it is evenly dispersed, take a purified water by weight and add it thereto, and stir until the film-forming agent is completely dissolved to obtain a standby solution B; Step 3: Take purified water by weight, add pH adjuster by weight, and stir until the pH adjuster is completely dissolved to obtain a standby solution C; Step 4: add the reserve solution A, the biguanide fungicide, the reserve solution B, the reserve solution C and the non-ionic surfactant in parts by weight in sequence, stir while adding, and finally circulate and stir for 20 minutes to obtain the non-iodine preparation cow teat dipping solution.