Immune cell protection storage device

Abstract

The invention belongs to the technical field of medical experiments, and particularly relates to an immune cell protection storage device which comprises a storage box, a liquid nitrogen row and storage tanks, a plurality of storage tanks are evenly clamped in the storage box, the storage box is connected with a pressurizing cover through a buckle, and the storage tanks are divided into inner tanks and outer tanks; a pressing type switch is arranged at the bottom of the inner tank, a sliding type rod body is installed at the bottom of the inner tank, the pressing type switch is attached to the rod body, a temperature sensor is arranged in the inner tank, and liquid nitrogen pipes are connected to the inner tank at equal intervals; and dry ice cavities are uniformly formed in the outer tank. According to the invention, which inner tank contains immune cells can be visually confirmed, the temperature rise time can be slowed down under the condition of insufficient liquid nitrogen, and the temperature of the inner tank and the outer tank can be ensured not to rise quickly within a period of time when the inner tank and the outer tank need to be moved integrally; and the opening of the dry ice cavity can be completed by the auxiliary assembly in a power failure state through the delayer.

Description

Technical Field

[0001] The invention relates to the technical field of medical experiments, in particular to an immune cell protection storage device. Background Art

[0002] Immune cell storage is used to prevent and treat certain diseases. The basic principle of immune cell storage is to extract immune cells from healthy individuals and then cryopreserve them under strict quality control. In this way, when needed in the future, these cells can be used to treat cancer, blood diseases, autoimmune diseases and certain genetic diseases. For some diseases, such as cancer and autoimmune diseases, stored immune cells may provide personalized treatment plans and help improve treatment effectiveness.

[0003] The existing patent (publication number CN117296832B) and a storage device for cell extraction, which stores cells separately through partitioning to facilitate access; it should be noted that immune cells need to be stored at ultra-low temperatures (such as liquid nitrogen, with a temperature as low as -196°C) for a long time;

[0004] Because immune cells also need to be checked regularly during storage to ensure their activity, purity, quantity, and any potential contamination or changes;

[0005] At present, it is inconvenient to conduct random inspections when storing immune cells. For example, in the above patent, when extracting immune cells, the immune cells will be directly exposed to the external temperature from -196°C, which will damage the immune cells. At the same time, in this patent, the partitioned storage container cannot be transferred. When the immune cells are taken, they need to be temporarily separated from the cooling system and exposed to the external temperature environment, which will directly affect the immune cells.

[0006] And considering that once the temperature of immune cells is too high, they will become ineffective as a whole, and considering the lack of timely supply of liquid nitrogen and power outages, the above patent and existing immune cell protection storage devices cannot cope with it.

[0007] Therefore, we propose an immune cell protection storage device, which is conducive to visually confirming which inner tank contains immune cells, slowing down the temperature rise time when liquid nitrogen is insufficient, and ensuring that the temperature of the inner tank and outer tank does not rise rapidly within a period of time when the inner tank and the outer tank need to be moved as a whole. In addition, the auxiliary components can open the dry ice chamber in the event of a power outage through a delay device. Summary of the invention

[0008] In order to overcome the above-mentioned defects of the prior art, the present invention provides an immune cell protection storage device to solve the problems existing in the above-mentioned background technology.

[0009] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an immune cell protection storage device, comprising a storage box, a liquid nitrogen row and a storage tank, wherein a plurality of storage tanks are evenly inserted and placed inside the storage box, the storage box is connected to a pressurized cover by a buckle, the storage tank is divided into an inner tank and an outer tank, a push-type switch is arranged at the bottom of the inner tank, a sliding rod body is installed at the bottom of the inner tank, the push-type switch and the rod body are fitted, a temperature sensor is built in the inner tank, and the inner tank is equidistantly connected to liquid nitrogen pipes;

[0010] The outer tank is evenly provided with dry ice chambers, and a self-opening and closing auxiliary component with a delay device is arranged on the top of the dry ice chamber, and the auxiliary component opens the dry ice chamber when the temperature detected by the temperature sensor is lower than the threshold value or the push switch is reset;

[0011] The liquid nitrogen row includes a pipe row, a control valve, a vacuum pipe, a pipe joint and a snap-fit ​​joint. The outer wall of the pipe row is equidistantly provided with pipe joints, the pipe joints are connected to the snap-fit ​​joints through vacuum pipes, the bottom of the liquid nitrogen pipe is connected to the snap-fit ​​joint through a snap-in pipe, and a matching control valve is installed on the pipe joint. The stop of the control valve corresponds to the auxiliary component opening the dry ice chamber.

[0012] Further: the auxiliary component includes a gear ring, a gear, a dry ice hole and a drive motor, the gear ring is evenly provided with dry ice holes in a ring shape, a gear meshing with the ring gear is arranged on one side of the outer tank, and the shaft of the gear is connected to the drive motor.

[0013] Furthermore: the inner wall of the inner tank is provided with annular grooves at equal intervals, a limiting ring is provided between every two groups of the annular grooves, and the temperature sensor is installed in the annular groove located in the middle of the inner tank.

[0014] Further: a snap-in wiring socket adapted to the inner tank is arranged on the outer side of the inner tank.

[0015] Furthermore: a notch is provided on the outer wall of the outer tank from bottom to top, and the notch exposes a portion of the gear ring, and the exposed portion of the gear ring meshes with the corresponding gear.

[0016] Furthermore: the branch pipes of the liquid nitrogen pipe are respectively connected to the corresponding multiple ring grooves, and the inner tank is screwed with a sealing cover.

[0017] Further: an external pipe socket is provided on the outer wall of the storage box, and the inlet pipe of the liquid nitrogen row is connected to the corresponding external pipe socket.

[0018] Further: the push-type switches are divided into two groups, the push-type switches in the inner group correspond to the rod body of the inner tank, and the push-type switches in the outer group are located at the bottom of the outer tank.

[0019] Compared with the prior art, the technical effects and advantages of the present invention are as follows:

[0020] 1) The immune cell protection storage device of the present invention, through the arrangement of auxiliary components, inner tank and outer tank, protects the immune cells by placing them in the core area of ​​the inner tank, detects whether the container of the immune cells enters the inner tank by a push-type switch, and turns on the liquid nitrogen when the inner tank has the immune cell container, and gaseous nitrogen appears in the corresponding inner tank, and detects the temperature in the inner tank by temperature sensing. When it is detected that the temperature in the inner tank exceeds the threshold range, the dry ice chamber is opened by the auxiliary component to expose the dry ice to the air, which can slow down the time for the temperature to rise in the core area of ​​the inner tank, which is beneficial for intuitively confirming which inner tank has immune cells, and is beneficial for slowing down the temperature rise time when liquid nitrogen is insufficient.

[0021] 2) The immune cell protection storage device of the present invention is provided with a push-type switch and a pressurized cover. When the control valve is closed, if the pressurized cover applies pressure to the inner tank through the buckle, so that the outer group of push-type switches are pressurized, and the inner group of push-type switches are subjected to the gravity of the inner tank and the immune cells, then the pressure is high. When the buckle is opened to remove the pressurized cover, the outer group of push-type switches are not subjected to pressure, and the inner group of push-type switches are subjected to the gravity of the inner tank and the immune cells, so that the pressure of the push-type switches is low. In this case, it is necessary to start the auxiliary component through a delay device to open the dry ice chamber, which is beneficial to ensure that the temperature of the inner tank and the outer tank will not rise rapidly within a period of time when it is necessary to move the inner tank and the outer tank as a whole. In addition, the auxiliary component can complete the opening of the dry ice chamber in a power outage through the delay device.

[0022] 3) The immune cell protection storage device of the present invention, through the setting of the control valve, when any control valve is closed and there is still an immune cell container in the inner tank of the drinking water, the corresponding auxiliary component is started, and the gear is driven to rotate by starting the driving motor, and then the gear meshes with the gear ring to rotate, so that the dry ice hole on the gear ring corresponds to the dry ice cavity, so that the dry ice inside the dry ice cavity is exposed to the external environment, so that the dry ice sublimates quickly, so that the external environment can be quickly cooled down, so that the immune cell container can be taken out without being affected by the external environment temperature. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of the external overall structure of the present invention;

[0024] Figure 2 It is a schematic diagram of the storage box structure of the present invention;

[0025] Figure 3 It is a schematic diagram of a single storage tank and a liquid nitrogen row structure of the present invention;

[0026] Figure 4 It is a schematic diagram of the internal structure of a single storage tank of the present invention;

[0027] Figure 5It is a schematic diagram of the liquid nitrogen row structure of the present invention;

[0028] Figure 6 It is a schematic diagram of the auxiliary component structure of the present invention;

[0029] Figure 7 It is a schematic cross-sectional view of the inner tank structure of the present invention;

[0030] Figure 8 It is a schematic cross-sectional view of the outer tank structure of the present invention.

[0031] The accompanying drawings are marked as follows: 1. storage tank; 11. inner tank; 111. sealing cover; 112. ring groove; 113. temperature sensor; 114. push switch; 115. liquid nitrogen tube; 116. limit ring; 12. dry ice chamber; 121. auxiliary component; 1211. gear ring; 1212. dry ice hole; 1213. gear; 1214. drive motor; 13. outer tank; 131. terminal block; 132. snap-in pipe; 14. liquid nitrogen row; 141. pipe row; 142. control valve; 143. vacuum pipe; 144. pipe joint; 145. snap-in joint; 2. storage box; 21. pressurized cover; 3. external pipe socket. DETAILED DESCRIPTION

[0032] The technical solution of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the present invention. In addition, the forms of the various structures recorded in the following embodiments are merely illustrative, and the structures involved in the present invention are not limited to the various structures recorded in the following embodiments. All other embodiments obtained by ordinary technicians in this field without making creative work belong to the scope of protection of the present invention.

[0033] Example:

[0034] See also Figure 1-8 The present invention provides a technical solution: an immune cell protection storage device, comprising a storage box 2, a liquid nitrogen row 14 and a storage tank 1, a liquid nitrogen tank is arranged outside the storage box 2, it should be noted that when operating the liquid nitrogen tank, appropriate protective equipment must be worn, such as a protective mask, goggles, cold-proof gloves and long-sleeved work clothes, and a plurality of storage tanks 1 are evenly inserted and placed inside the storage box 2;

[0035] It should be noted that the storage of immune cells needs to be carried out at an ultra-low temperature of -196°C, so they are often stored in liquid nitrogen;

[0036] The storage box 2 is connected to a pressurized cover 21 by a buckle, and the pressurized tank can be taken out by opening the buckle. The storage tank 1 is divided into an inner tank 11 and an outer tank 13. A push switch 114 is arranged at the bottom of the inner tank 11. A sliding rod body is installed at the bottom of the inner tank 11. The push switch 114 fits the rod body. The push switch 114 is divided into two groups, an inner group and an outer group. The push switch 114 of the inner group corresponds to the rod body of the inner tank 11, and the push switch 114 of the outer group is located at the bottom of the outer tank 13. When the container of immune cells is placed in the inner tank 11, Under the gravity of the immune cell container, the rod body presses the push switch 114 as it sinks, and then the immune cell container is fed back into the inner tank 11, and then the control valve 142 corresponding to the inner tank 11 is started. The control valve 142 is opened, and the liquid nitrogen in the external liquid nitrogen tank is sent into the inner tank 11 through the pipeline to quickly form a rapid cooling. The inner tank 11 is built with a temperature sensor 113, and the temperature inside the inner tank 11 is detected by the temperature sensor 113. The temperature sensor 113 needs to use a special ultra-low temperature sensor;

[0037] The outer tank 13 is evenly provided with dry ice chambers 12, and external dry ice is placed in the dry ice chambers 12. A self-opening and closing auxiliary component 121 with a delay device is arranged on the top of the dry ice chamber 12. The auxiliary component 121 opens the dry ice chamber 12 when the temperature detected by the temperature sensor 113 is lower than a threshold value or the push switch 114 is reset;

[0038] When the temperature sensor 113 is in an online state, when the temperature detected by the temperature sensor 113 gradually increases and rises to -150°C, the dry ice chamber 12 needs to be opened through the auxiliary component 121 to expose the dry ice directly to the air. The dry ice will absorb heat and directly transform from solid to gas. During the sublimation process, the dry ice needs to absorb a large amount of heat, thereby reducing the temperature of the surrounding substances to achieve a cooling effect, thereby delaying the temperature increase of the inner tank 11 and the outer tank 13. This situation is often caused by insufficient liquid nitrogen in the external liquid nitrogen pipe 115, or the liquid nitrogen pipe 115 is damaged and the liquid nitrogen cannot enter the inner tank 11;

[0039] When the inner tank 11 and the outer tank 13 are separated from the storage box 2, the push switch 114 is reset due to lack of gravity pressing, and the auxiliary component 121 is activated through the delay device, so that the auxiliary component 121 opens the dry ice chamber 12. In such a situation, the inner tank 11 and the outer tank 13 need to be taken out and moved, and the immune cells need to be taken out;

[0040] At the same time, it should be noted that if the pressure-added cover 21 applies pressure to the inner tank 11 through the buckle, so that the outer group push-type switch 114 is under pressure, and the inner group push-type switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, the pressure is high. When the buckle is opened to remove the pressure-added cover 21, the outer group push-type switch 114 is not under pressure, and the inner group push-type switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, so that the pressure of the push-type switch 114 is low. In this case, the auxiliary component 121 needs to be started by a timer to open the dry ice chamber 12. At this time, the container of the immune cells needs to be transferred, and the transfer of the inner tank 11 and the outer tank 13 also requires a transfer tool, and the action needs to be slow. This will leave sufficient operating time for the auxiliary component 121 to complete the opening of the dry ice chamber 12 when the outer tank 13 is separated from the storage box 2.

[0041] The auxiliary component 121 includes a gear ring 1211, a gear 1213, a dry ice hole 1212, and a driving motor 1214. The dry ice holes 1212 are evenly opened in a ring shape on the gear ring 1211. A gear 1213 meshing with the ring gear is provided on one side of the outer tank 13. The shaft of the gear 1213 is connected to the driving motor 1214. The gear 1213 is driven to rotate by starting the driving motor 1214, and then the gear 1213 meshes with the gear ring 1211 to rotate, so that the dry ice hole 1212 on the gear ring 1211 corresponds to the dry ice chamber 12, so that the dry ice inside the dry ice chamber 12 is exposed to the external environment, so that the dry ice sublimates quickly.

[0042] It should be noted that dry ice will cause pressure to increase in a sealed space, which may cause an explosion. Therefore, the dry ice chamber 12 does not need to be completely sealed. It should also be noted that dry ice will not sublime at -78.5°C. Since the outer tank 13 and the inner tank 11 are integrally formed, when the temperature of the inner tank 11 drops to about -196°C under the action of liquid nitrogen, the temperature of the outer tank 13 will not be higher than -78.5°C. Therefore, under normal conditions of the liquid nitrogen pipe 115, dry ice will not sublime.

[0043] The liquid nitrogen row 14 includes a pipe row 141, a control valve 142, a vacuum pipe 143, a pipe joint 144 and a snap joint 145. The outer wall of the pipe row 141 is equidistantly provided with pipe joints 144. The number of pipe joints 144 is the same as the number of the inner tank 11, and they correspond one to one. The pipe joint 144 is connected to the snap joint 145 through the vacuum pipe 143. The bottom of the liquid nitrogen pipe 115 is connected to the snap joint 145 through the snap-in pipe 132. By snapping the snap-in pipe 132 and the snap joint 145 together, the liquid nitrogen passes through the vacuum pipe 143. The liquid nitrogen enters the inner tank 11 through the snap-in pipe 132 and the snap-in joint 145. The pipe joint 144 is equipped with an adaptive control valve 142. The stop of the control valve 142 corresponds to the auxiliary component 121 opening the dry ice chamber 12. The delivery of liquid nitrogen is controlled by the control valve 142. When the control valve 142 stops, it means that the inner tank 11 and the outer tank 13 may need to be taken out. In order to ensure safety, the control valve 142 is closed to stop the delivery of liquid nitrogen, or the container of immune cells needs to be directly taken out and placed in the external storage box 2.

[0044] The inner tank 11 is equidistantly connected with a liquid nitrogen pipe 115, and the branch pipes of the liquid nitrogen pipe 115 are respectively connected to the plurality of annular grooves 112, and the number of the annular grooves 112 is the same as the number of the branch pipes of the liquid nitrogen pipe 115. The inner tank 11 is screwed with a sealing cover 111, and the sealing cover 111 is clamped on the top of the inner tank 11 to form a closure;

[0045] It should be noted that the engagement of the sealing cover 111 with the inner tank 11 is not completely sealed, and a small gap needs to be reserved for the gaseous nitrogen to flow out.

[0046] The outer wall of the storage box 2 is provided with an external pipe socket 3, the inlet pipe of the liquid nitrogen row 14 is connected to the corresponding external pipe socket 3, and the external liquid nitrogen tank is connected to the corresponding external pipe socket 3. It should be noted that the two should be avoided from being too close.

[0047] Among them, the inner wall of the inner tank 11 is equidistantly provided with annular grooves 112, and a limiting ring 116 is arranged between every two groups of the annular grooves 112. The limiting ring 116 is made of soft material. The container of immune cells is placed in the inner tank 11, and the position of the container of immune cells is fixed by the limiting ring 116 to prevent the container of immune cells from shaking in the inner tank 11. The temperature sensor 113 is installed in the annular groove 112 located in the middle of the inner tank 11.

[0048] In practical applications, the temperature sensor 113 needs to be placed at key positions of the inner tank 11, such as the top, bottom and side walls, to comprehensively monitor the temperature distribution inside the tank. Since the boiling point of liquid nitrogen is extremely low and there is convection in the tank, the temperature at different positions may be different. Therefore, by installing multiple temperature sensors 113, more comprehensive and accurate temperature data can be obtained.

[0049] The outer wall of the outer tank 13 is provided with a notch from bottom to top, and the notch partially exposes the toothed ring 1211, and the exposed part of the toothed ring 1211 meshes with the corresponding gear 1213. Figure 4 and Figure 8 By setting the notch, the inner tank 11 and the outer tank 13 can be better engaged and placed, and the gear ring 1211 and the gear 1213 can be easily matched.

[0050] Among them, a snap-in wiring seat 131 adapted to the inner tank 11 is arranged outside the inner tank 11, and the connection method of the wiring seat 131 is similar to the connection method of the snap-in pipe 132 and the snap-in joint 145, and the wiring seat 131 is connected to the temperature sensor 113;

[0051] Alternatively, a set of power supply modules and communication modules are arranged on the outer wall of the outer tank 13, the temperature sensor 113 is powered by the power supply module, and the temperature signal is sent by the communication module;

[0052] This device needs to be used together with a liquid nitrogen tank and a control module. When the liquid level in the liquid nitrogen tank is too low and the temperature detected by the temperature sensor 113 exceeds the threshold range, the control module activates the alarm. After the inner tank 11 and the outer tank 13 are installed and the container of the immune cells is placed, the control valve 142 is activated to allow the liquid nitrogen to quickly enter the inner tank 11.

[0053] Working principle in the embodiment of the present invention: This device is used with a liquid nitrogen tank;

[0054] The immune cell container is sent into the inner tank 11 by opening the sealing cover 111. Under the action of gravity, the immune cell container presses the inner group push switch 114 through the rod body, and then the sealing cover 111 is closed. At this time, the buckle applies pressure to the inner tank 11 by the pressure cover 21, so that the outer group push switch 114 is pressurized, and the inner group push switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, so the pressure is high. After the inner group push switch 114 determines that the immune cell container has entered the inner tank 11, the external liquid nitrogen tank is started to connect to the external pipe seat 3 through the vacuum pipe 143, and the external pipe seat 3 is connected to the pipe row 141, and multiple pipe joints 144 and multiple control valves 142 are connected through the pipe row 141. By snapping and connecting the snap-in pipe 132 and the snap-in joint 145, liquid nitrogen passes through the vacuum pipe 143, the snap-in pipe 132 and the snap-in joint 145, and the liquid nitrogen pipe 115 enters the inner tank 11;

[0055] When it is necessary to partially extract any immune cell container, the control valve 142 is closed, and if there is still an immune cell container in the drinking inner tank 11, the corresponding auxiliary component 121 is started, and the gear 1213 is driven to rotate by starting the driving motor 1214, and then the gear 1213 engages the gear ring 1211 to rotate, so that the dry ice hole 1212 on the gear ring 1211 corresponds to the dry ice chamber 12, so that the dry ice inside the dry ice chamber 12 is exposed to the external environment, so that the dry ice sublimates quickly, so that the external environment can be quickly cooled;

[0056] The temperature in the inner tank 11 is detected by temperature sensing. When it is detected that the temperature in the inner tank 11 exceeds a threshold range, the dry ice chamber 12 is opened by the auxiliary component 121 so that the dry ice is exposed to the air, which can slow down the time for the temperature in the core area of ​​the inner tank 11 to rise.

[0057] When the entire immune cell container needs to be taken, the control valve 142 is closed. If the pressure cover 21 is pressed on the inner tank 11 by the buckle, so that the outer group push-type switch 114 is pressurized, and the inner group push-type switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, the pressure is high. When the buckle is opened to remove the pressure cover 21, the outer group push-type switch 114 is not subjected to pressure, and the inner group push-type switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, so that the pressure of the push-type switch 114 is low, then it is necessary to start the auxiliary component 121 through the delay device to open the dry ice chamber 12;

[0058] When the inner tank 11 and the outer tank 13 of the entire storage box 2 are transferred, if the pressure cover 21 applies pressure to the inner tank 11 through the buckle, so that the outer group push-type switch 114 is under pressure, and the inner group push-type switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, the pressure is high. When the buckle is opened to remove the pressure cover 21, the outer group push-type switch 114 is not under pressure, and the inner group push-type switch 114 is subjected to the gravity of the inner tank 11 and the immune cells, so that the pressure of the push-type switch 114 is low. In this case, it is necessary to start the auxiliary component 121 through a delay device to open the dry ice chamber 12. The delay device can be used to allow the auxiliary component 121 to complete the opening of the dry ice chamber 12 in a power outage.

[0059] The basic principles and main features of the present invention and the advantages of the present invention are shown and described above. For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention; therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is limited by the attached claims rather than the above description. Therefore, it is intended to include all changes within the meaning and scope of the equivalent elements of the claims in the present invention, and any figure marks in the claims should not be regarded as limiting the claims involved.

[0060] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An immune cell protection storage device, comprising a storage box (2) and a storage tank (1), wherein a plurality of storage tanks (1) are evenly inserted and placed inside the storage box (2), characterized in that: The storage box (2) is connected to a pressurized cover (21) via a buckle, the storage tank (1) is divided into an inner tank (11) and an outer tank (13), a push switch (114) is arranged at the bottom of the inner tank (11), a sliding rod body is installed at the bottom of the inner tank (11), the push switch (114) and the rod body are in contact, a temperature sensor (113) is built in the inner tank (11), and liquid nitrogen pipes (115) are equidistantly connected to the inner tank (11); The outer tank (13) is evenly provided with dry ice chambers (12), and a self-opening and closing auxiliary component (121) with a time delay device is arranged on the top of the dry ice chamber (12), and the auxiliary component (121) opens the dry ice chamber (12) when the temperature detected by the temperature sensor (113) is lower than a threshold value or the push switch (114) is reset; The liquid nitrogen row (14) comprises a tube row (141), a control valve (142), a vacuum pipe (143), a pipe joint (144) and a snap-fit ​​joint (145); the outer wall of the tube row (141) is provided with pipe joints (144) at equal intervals; the pipe joints (144) are connected to the snap-fit ​​joint (145) via the vacuum pipe (143); the bottom of the liquid nitrogen tube (115) is connected to the snap-fit ​​joint (145) via a snap-in pipe (132); a matching control valve (142) is installed on the pipe joint (144); the stop of the control valve (142) corresponds to the auxiliary component (121) opening the dry ice chamber (12).

2. The immune cell protection storage device according to claim 1, characterized in that: The auxiliary component (121) comprises a gear ring (1211), a gear (1213), dry ice holes (1212) and a driving motor (1214); the gear ring (1211) is provided with dry ice holes (1212) in a uniform annular shape; a gear (1213) meshing with the ring gear is provided on one side of the outer tank (13); and the shaft of the gear (1213) is connected to the driving motor (1214).

3. The immune cell protection storage device according to claim 1, characterized in that: The inner wall of the inner tank (11) is provided with annular grooves (112) at equal intervals, a limiting ring (116) is provided between every two groups of the annular grooves (112), and the temperature sensor (113) is installed in the annular groove (112) located in the middle of the inner tank (11).

4. The immune cell protection storage device according to claim 1, characterized in that: A snap-in wiring socket (131) adapted to the inner tank (11) is arranged outside the inner tank (11).

5. The immune cell protection storage device according to claim 2, characterized in that: A notch is provided from bottom to top on the outer wall of the outer tank (13), and the notch partially exposes the toothed ring (1211), and the exposed portion of the toothed ring (1211) meshes with the corresponding gear (1213).

6. The immune cell protection storage device according to claim 1, characterized in that: The branch pipes of the liquid nitrogen pipe (115) are respectively connected to the corresponding plurality of annular grooves (112), and the inner tank (11) is screwed with a sealing cover (111).

7. The immune cell protection storage device according to claim 1, characterized in that: An external pipe socket (3) is provided on the outer wall of the storage box (2), and an inlet pipe of the liquid nitrogen row (14) is connected to the external pipe socket (3).

8. The immune cell protection storage device according to claim 1, characterized in that: The push-type switches (114) are divided into two groups, an inner group and an outer group. The push-type switches (114) in the inner group correspond to the rod body of the inner tank (11), and the push-type switches (114) in the outer group are located at the bottom of the outer tank (13).

Images