Sample application equipment

By designing automated spotting equipment, including spotting, cylinder expansion, infiltration and color development devices, the problem of traditional equipment being affected by human factors is solved, and the consistency of experimental results and an efficient workflow is achieved.

CN119643768APending Publication Date: 2025-03-18SUZHOU MEGAROBO TECH CO LTD
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Patent Information

Application Number
CN202411669195.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-21
Publication Date
2025-03-18

AI Technical Summary

Technical Problem

Traditional sample sampling equipment is greatly affected by human factors, resulting in inconsistent experimental results and low efficiency, which cannot meet the timeliness of the experiment.

Method used

An automated spotting device is designed, including a spotting device, a cylinder expansion device, an infiltration device and a color development device. Through these devices, automatic spotting, expansion, infiltration and color development of the spotting liquid can be realized.

Benefits of technology

The automation level of the spotted equipment is improved, the impact of labor costs and human factors is reduced, the consistency of experimental results is ensured, and the work efficiency is improved, meeting the timeliness of the experiment.

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Abstract

The embodiment of the invention provides sample application equipment. The sample application equipment comprises a sample application device and a sample application device, wherein the sample application device is used for applying a sample application solution to a sample application plate; the expanding cylinder device comprises an expanding cylinder and a placing frame, the expanding cylinder comprises a cavity, an opening is formed in one end of the cavity, the cavity is connected with a plurality of liquid inlet pipes for injecting a developing solvent into the cavity according to a preset proportion and a liquid discharging pipe for discharging the developing solvent in the cavity, and the sample application plate after sample application is arranged in the cavity through the placing frame. The developing agent in the cavity is spread on the point sample plate; the infiltrating device is used for infiltrating the unfolded point sample plate; and the color developing device is used for developing the infiltrated dot sample plate. By arranging the sample application device, the cylinder expansion device, the infiltration device and the color development device, automatic sample application, expansion, infiltration and color development of the sample application plate can be realized. Therefore, the automation degree of the sample application equipment is relatively high, so that the labor cost and the influence of human factors can be greatly reduced.
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Description

Technical Field

[0001] The present invention relates to the field of spotting technology, in particular to a spotting device. Background Art

[0002] Thin layer chromatography spotting experiments are widely used in the fields of chemistry, biology, medicine, environment, etc. Taking the field of chemistry as an example, thin layer chromatography spotting experiments can be used to separate and identify compounds: by smearing the mixture to be separated on the thin layer chromatography plate and then conducting experimental analysis, the relative mobility and relative content of each component can be obtained, thereby achieving the separation and identification of the mixture; in addition, thin layer chromatography spotting experiments can also be used to analyze the progress and products of the reaction: by taking samples during the reaction and then analyzing them on the thin layer chromatography plate, the progress of the reaction and the generation of the products can be understood.

[0003] The thin layer chromatography spotting experiment requires spotting on a spotting plate. After the spotting is completed, the spotting plate needs to be developed, infiltrated and colored in sequence. Then, relevant personnel can record and analyze the experimental results such as the finished color image to provide a basis for research in related fields. The experimental results include but are not limited to Rf value and / or target spot size.

[0004] Traditional spotting equipment basically connects the entire experimental process manually. Inevitably, the spotting equipment is greatly affected by human factors. Different operators and different operating methods may lead to very different experimental results, which in turn has a great impact on related research. In addition, the efficiency of manual labor is low and cannot meet the timeliness of the experiment. Summary of the invention

[0005] In order to at least partially solve the problems existing in the prior art, an embodiment of the present invention provides a spotting device. The spotting device includes: a spotting device, which is used to spot the spotting liquid on the spotting plate; a display cylinder device, which includes a display cylinder and a placement rack, the display cylinder includes a cavity and an opening is formed at one end of the cavity, the cavity is connected to a plurality of liquid inlet pipes for injecting a developing agent into the cavity according to a predetermined ratio, and a liquid discharge pipe for discharging the developing agent in the cavity, the spotting plate after spotting is arranged in the cavity through the placement rack, so that the developing agent in the cavity is developed on the spotting plate; an infiltration device, which is used to infiltrate the developed spotting plate; and a color development device, which is used to develop the color of the infiltrated spotting plate.

[0006] Exemplarily, the placement rack includes a support portion erected on the edge of the opening and a positioning portion connected to the support portion and located in the display cylinder. The spotting plate is positioned in the cavity by the positioning portion. An insertion port is formed on the support portion, and the insertion port is connected to the opening.

[0007] Exemplarily, the positioning portion is formed by extending the edge of the insertion port from the opening into the cavity, and the bottom of the positioning portion is suspended.

[0008] Exemplarily, the positioning portion defines a height direction in which the spot template is parallel to the developing agent in the cavity; or

[0009] Exemplarily, the spotting plate has a first end close to the opening and a second end away from the opening, and the positioning portion defines that the spotting plate gradually moves away from the positioning portion from the first end to the second end.

[0010] Exemplarily, the positioning portion is provided with positioning grooves with opening directions opposite to each other and both facing the center of the cavity, and the spotting plate inserted into the cavity through the insertion opening extends into the positioning groove and is positioned through the positioning groove.

[0011] Exemplarily, a blowing member is provided in the cavity for blowing air to the spotting plate located in the cavity.

[0012] Exemplarily, the display cylinder device includes multiple display cylinder groups, each display cylinder group includes two display cylinders, and the two display cylinders in each display cylinder group are connected by a display cylinder connecting piece, which fixes the relative positions of the two display cylinders; the two display cylinders in each display cylinder group are each provided with a blowing piece for blowing air to the spotting plate located in the cavity, and a baffle is provided on the display cylinder connecting piece, which is located between the two display cylinders and separates the two display cylinders, and the top of the baffle is not lower than the opening.

[0013] Exemplarily, the spotting device includes a spotting frame, a driving component and a spotting component, the main body of the driving component is arranged on the spotting frame, the spotting component includes a spotting needle connected to the driving component and a capping member having a penetration hole, the spotting needle can be raised and lowered along the penetration hole, and the driving component is configured as follows: after the capping member is driven to press the bottle cap of the sample bottle, the spotting needle is driven to pass through the penetration hole and extend into the sample bottle to absorb the spotting liquid in the sample bottle, after the spotting needle that has completed the liquid absorption is driven to pass through the penetration hole and detach from the sample bottle, the capping member is driven to detach from the bottle cap, and then the spotting needle is driven to spot the spotting liquid onto the spotting plate.

[0014] Exemplarily, the capping member includes a capping plate and an expansion boss protruding downward from the capping plate, the through hole passes through the capping plate and the expansion boss, the driving assembly is used to drive the capping plate to press and detach the bottle cap, and the expansion boss is used to expand the sealing layer on the bottle cap to separate the sealing layer from the spotting needle.

[0015] Exemplarily, the spotting device also includes an elastic component, which includes a pressure rod and an elastic member. The upper end of the elastic member is connected to the driving end of the driving component and the lower end is connected to the pressure rod. The driving component is used to drive the pressure rod to press and disengage the bottle cap. The pressure rod presses the bottle cap when the expansion boss expands the sealing layer to compress the elastic member and make the elastic member have elastic potential energy to drive the pressure rod to protrude downward from the expansion boss.

[0016] Exemplarily, the color developing device includes a heated color developing device, which includes a heater, a storage table and a heated image acquisition component. The storage table has a working surface on which a spotting plate can be placed. A cavity is formed inside the storage table. The cavity is connected to the heater through a first heating channel. The cavity extends on opposite sides of a first direction to form a second heating channel and a third heating channel. A first air outlet is formed on an end of the second heating channel away from the cavity, and a second air outlet is formed on an end of the third heating channel away from the cavity. There is a gap between the first air outlet and the second air outlet, and both blow air toward the working surface. The heated image acquisition component collects the color development of the spotting plate placed on the working surface through the gap.

[0017] Exemplarily, a connecting plate is provided on the storage table, a connecting plate opening is provided on the connecting plate, the first heating channel passes through the connecting plate opening and is connected to the cavity, and a heat insulating member is provided on at least one side of the connecting plate in a second direction perpendicular to the first direction.

[0018] Exemplarily, the heating color developing device includes a box body, a storage table, a second heating channel and a third heating channel are all located inside the box body, the heater is located outside the box body, the first heating channel passes through a side surface of the box body and is connected between the storage table and the heater, the box body is provided with an operation window, a door body and a door body driving component, the dot pattern plate is placed on the working surface through the operation window, the door body driving component is connected to the door body, and the door body moves between a first position of covering the operation window and a second position of opening the operation window through the door body driving component.

[0019] The spotting device provided in the embodiment of the present invention can realize automatic spotting, spreading, soaking and coloring of the spotting plate by setting a spotting device, a display device, an infiltration device and a coloring device. In this way, the spotting device has a high degree of automation, which can greatly reduce labor costs and the influence of human factors. Based on this, the spotting device can make the consistency of experimental results higher, thereby providing a good foundation for research in related fields. In addition, the spotting device has a high working efficiency, which can meet the timeliness of the experiment.

[0020] A series of simplified concepts are introduced in the summary of the invention, which will be further described in detail in the detailed description. The summary of the invention does not mean to attempt to define the key features and essential technical features of the claimed technical solution, nor does it mean to attempt to determine the scope of protection of the claimed technical solution.

[0021] The advantages and features of the present invention are described in detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The following drawings of the present invention are used as part of the present invention for understanding the present invention. The drawings show the embodiments of the present invention and their descriptions, and are used to explain the principles of the present invention. In the drawings,

[0023] Figure 1 A schematic diagram of a spotting device according to an exemplary embodiment of the present invention;

[0024] Figure 2 A three-dimensional view of a cylinder display device according to an exemplary embodiment of the present invention at one angle;

[0025] Figure 3 for Figure 2 A three-dimensional view of another angle of the display cylinder device shown in FIG.

[0026] Figure 4 for Figure 2 An exploded view of the display cylinder device shown in FIG.

[0027] Figure 5 for Figure 2 A perspective view of an angle of the placement rack shown in FIG.

[0028] Figure 6 for Figure 5 A perspective view of another angle of the placement rack shown in FIG.

[0029] Figure 7 for Figure 5 A perspective view of the placement rack shown in another angle;

[0030] Figure 8 is a perspective view of a spotting device according to an exemplary embodiment of the present invention;

[0031] Fig. 9 for Figure 8 A three-dimensional diagram of a partial structure of the spotting device shown in FIG.

[0032] Fig.10 for Fig. 9 A front view of a partial structure of the spotting device shown in FIG.

[0033] Fig.11 for Fig.10 A cross-sectional view of a partial structure of the spotting device shown in FIG.

[0034] Fig.12 for Fig. 9 A perspective view of the gland member shown in FIG.

[0035] Fig.13 is a perspective view of a heating color developing device according to an exemplary embodiment of the invention;

[0036] Fig.14 for Fig.13 A perspective view of a partial structure of a heating color developing device shown in FIG.

[0037] Fig.15 for Fig.14 A top view of the storage table shown in FIG.

[0038] Fig.16A for Fig.14 A cross-sectional view of the storage table shown in FIG.

[0039] Fig. 16B for Fig.14 A cross-sectional view of a partial structure of a heating color developing device shown in FIG.

[0040] Fig.17 for Fig.13 A three-dimensional view of another partial structure of the heating color developing device is shown in FIG.

[0041] The above drawings include the following reference numerals:

[0042] 1000, spotting device; 1100, spotting frame; 1110, first horizontal driving member; 1120, second horizontal driving member; 1200, driving assembly; 1210, first driving member; 1220, second driving member; 1230, third driving member; 1240, first connecting frame; 1250, second connecting frame; 1260, third connecting frame; 1270, first slide rail; 1280, second slide rail; 1291, first lead screw; 1292, first nut; 1293, second lead screw; 1294, second nut; 1300, spotting assembly; 1310, spotting needle; 1311 , needle tube; 1312, needle; 1313, piston rod; 1320, cover member; 1321, through hole; 1322, expansion boss; 1323, positioning boss; 1324, cover plate; 1325, pressure rod through hole; 1400, elastic component; 1410, pressure rod; 1411, pressing part; 1412, extension rod; 1420, elastic member; 2000, cylinder display device; 2100, cylinder display; 2110, opening; 2120, cavity; 2130, frame; 2131, observation surface; 2200, placement frame; 2210, support part; 2211, insertion port; 222 0, positioning part; 2221, positioning groove; 2300, liquid inlet pipe; 2400, liquid discharge pipe; 2500, exhibition cylinder connecting piece; 2510, baffle; 2600, cover assembly; 2610, cover; 2620, cover drive; 2700, exhibition cylinder image acquisition piece; 2800, liquid inlet pump; 2900, liquid discharge pump; 3000, immersion device; 4000, color development device; 4100, heating color development device; 4200, heater; 4300, storage table; 4310, working surface; 4320, second heating channel; 4321, first air outlet; 4330, third heating channel channel; 4331, second air outlet; 4340, cavity; 4350, limit groove; 4360, connecting plate; 4370, positioning column; 4400, first heating channel; 4500, heat insulation; 4600, storage plate; 4610, supporting protrusion; 4620, mounting plate; 4621, mounting through hole; 4700, box body; 4710, operation window; 4720, door body; 4730, door body driving member; 4900, ultraviolet color development device; 7000, spotting plate loading device; 8000, spotting liquid loading device; 9100, spotting plate; 9101, first end of spotting plate. DETAILED DESCRIPTION

[0043] In the following description, a large amount of details are provided so that the present invention can be thoroughly understood. However, it will be appreciated by those skilled in the art that the following description only exemplarily illustrates a preferred embodiment of the present invention, and the present invention can be implemented without one or more such details. In addition, in order to avoid confusion with the present invention, some technical features well known in the art are not described in detail.

[0044] The embodiment of the present invention provides a sample spotting device. The sample spotting device can be used for thin layer chromatography sample spotting experiments. The sample spotting device of the embodiment of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0045] like Figure 1 As shown, the spotting device may include a spotting device 1000 , a display tank device 2000 , an immersion device 3000 , and a color development device 4000 .

[0046] The spotting device 1000 can be used to spot the spotting liquid onto the spotting plate 9100. The spotting liquid can be different liquids according to different requirements.

[0047] Combination Figure 2-3As shown, the display cylinder device 2000 may include a display cylinder 2100 and a placement rack 2200. The display cylinder 2100 may include a cavity 2120. An opening 2110 may be formed at one end (usually the upper end) of the cavity 2120. The spotting plate 9100 may extend into the cavity 2120 through the opening 2110. The spotting plate 9100 after spotting may be placed in the cavity 2120 through the placement rack 2200, so that the developing agent in the cavity 2120 is developed on the spotting plate 9100. It is not strictly limited here that when the spotting plate 9100 is placed in the cavity 2120, the spotting plate 9100 is completely located in the cavity 2120. When the spotting plate 9100 is placed in the cavity 2120, a part of the spotting plate 9100 may be located in the cavity 2120, and the spotting plate 9100 may also have a part extending out of the cavity 2120. The placement rack 2200 may be at least partially located in the cavity 2120. The placement rack 2200 may guide the spotting plate 9100 to extend into the cavity 2120. For example, the placement rack 2200 may have a portion arranged at the edge of the opening 2110 and a portion extending into the cavity 2120, and the portion of the placement rack 2200 extending into the cavity 2120 may guide the spotting plate 9100 to extend into the cavity 2120. Of course, the placement rack 2200 may also include any other suitable structure. The cavity 2120 may be connected to a plurality of liquid inlet pipes 2300 for injecting a developing agent into the cavity 2120 according to a predetermined ratio, and a liquid discharge pipe 2400 for discharging the developing agent in the cavity 2120. The plurality of liquid inlet pipes 2300 may be respectively connected to an external developing agent supply device, and the external developing agent supply device may inject a developing agent into the cavity 2120 through the liquid inlet pipes 2300. The developing agent supply devices connected to the multiple liquid inlet tubes 2300 can be different, that is, the multiple liquid inlet tubes 2300 can respectively transport different developing agents. By controlling the developing agent flow rates passing through the multiple liquid inlet tubes 2300, the multiple liquid inlet tubes 2300 can inject developing agents into the cavity 2120 according to a predetermined ratio. Here, the control of the developing agent flow rates passing through the multiple liquid inlet tubes 2300 can be achieved in any suitable form. For example, the multiple liquid inlet tubes 2300 can have different structures, so that the multiple liquid inlet tubes 2300 can have different flow areas inside, so that the developing agent flow rates passing through the multiple liquid inlet tubes 2300 are different. Through appropriate structural design, the multiple liquid inlet tubes 2300 can inject developing agents into the cavity 2120 according to a predetermined ratio. Alternatively, multiple liquid inlet pipes 2300 may be connected to liquid inlet pumps 2800, respectively, and the flow rate may be controlled by the liquid inlet pumps 2800 of the multiple liquid inlet pipes 2300, so that the multiple liquid inlet pipes 2300 can inject the developing agent into the cavity 2120 according to a predetermined ratio. There may be one or more liquid discharge pipes 2400. The end of the liquid discharge pipe 2400 away from the display cylinder 2100 may be connected to a waste liquid tank, or may be directly connected to the outside.The drain pipe 2400 can discharge the developing agent in the cavity 2120 in any suitable form. For example, the drain pipe 2400 can be connected to a drain pump 2900. When the developing agent in the cavity 2120 needs to be discharged, the developing agent in the cavity 2120 can be discharged through the drain pipe 2400 under the action of the drain pump 2900. The drain pipe 2400 can also be connected to the bottom of the cavity 2120, and the drain pipe 2400 can be connected to a control valve. When the control valve controls the drain pipe 2400 to open, the developing agent in the cavity 2120 can enter the drain pipe 2400 and be discharged to the outside. The drain pipe 2400 can also discharge the developing agent in the cavity 2120 using the siphon principle, which will not be described in detail here. In actual applications, after the drain pipe 2400 discharges the developing agent in the cavity 2120, the inlet pipe 2300 can inject the same developing agent into the cavity 2120, so that the cavity 2120 can be cleaned. Then, the drain pipe 2400 can discharge the developing agent in the cavity 2120. In this way, the expansion tank device 2000 can be ready for the next expansion.

[0048] The infiltration device 3000 can be used to infiltrate the expanded spot plate 9100. Specifically, the infiltration tank of the infiltration device 3000 can contain an infiltration agent. After the spot plate 9100 is extended into the infiltration tank, the infiltration agent can infiltrate the spot plate 9100. Exemplarily, the infiltration device 3000 can have a plurality of infiltration tanks. Each infiltration tank can contain a different infiltration agent. In this way, according to different needs, the spot plate 9100 can select different infiltration agents for infiltration.

[0049] The color developing device 4000 can be used to develop the color of the infiltrated spot plate 9100. The color developing device 4000 can develop the color of the spot plate 9100 by any suitable method such as ultraviolet rays or heating.

[0050] In actual application, the spotting device needs to spot the spotting liquid onto the spotting plate 9100 through the spotting device 1000. After the spotting is completed, the spotting plate 9100 can be moved to the display cylinder device 2000, so that it can be placed in the cavity 2120 of the display cylinder 2100 through the placement rack 2200. In this way, the developing agent in the cavity 2120 can spread upward from the bottom of the spotting plate 9100 to achieve development. Exemplarily, when the development front of the developing agent spreads to 80%-90% of the height of the spotting plate 9100, the development is completed. After the development is completed, the spotting plate 9100 can be moved to the infiltration device 3000, and the infiltration device 3000 can infiltrate the spotting plate 9100. Exemplarily, the infiltration agent can infiltrate the entire developed portion of the spotting plate 9100 (i.e., the portion where the developing agent spreads on the spotting plate 9100). After the infiltration is completed, the spot plate 9100 can be moved to the color developing device 4000, and the color developing device 4000 can develop the color of the spot plate 9100. In this way, relevant personnel can record and analyze the color image on the spot plate 9100, so as to carry out subsequent analysis and research.

[0051] In summary, the spotting device provided in the embodiment of the present invention can realize automatic spotting, spreading, infiltration and coloring of the spotting plate 9100 by setting the spotting device 1000, the display cylinder device 2000, the infiltration device 3000 and the coloring device 4000. In this way, the spotting device has a high degree of automation, which can greatly reduce labor costs and the influence of human factors. Based on this, the spotting device can make the consistency of experimental results higher, thereby providing a good foundation for research in related fields. In addition, the spotting device has a high working efficiency, which can meet the timeliness of the experiment.

[0052] For example, Figure 5-7As shown, the placement rack 2200 may include a support portion 2210 and a positioning portion 2220. The support portion 2210 may be arranged on the edge of the opening 2110. The support portion 2210 may be simply arranged on the edge of the opening 2110, or may be arranged on the edge of the opening 2110 by snapping, threading or any other means. The support portion 2210 may cover the opening 2110, and the placement rack 2200 having such a support portion 2210 may be arranged on the edge of the opening 2110 more stably. An insertion port 2211 may be formed on the support portion 2210, and the insertion port 2211 may be connected to the opening 2110. Since the support portion 2210 is arranged on the opening 2110, the support portion 2210 may be higher than the opening 2110, so that the insertion port 2211 may be higher than the opening 2110. When the spotting plate 9100 extends into the cavity 2120, it may first pass through the insertion port 2211 and then pass through the opening 2110. The positioning portion 2220 can be connected to the support portion 2210 and located in the display cylinder 2100. The spotting plate 9100 can be positioned in the cavity 2120 by the positioning portion 2220. By the support portion 2210 being set on the edge of the opening 2110, such a placement rack 2200 can be more stably set on the edge of the opening 2110, so that the structure of the overall device can be more stable, and such a placement rack 2200 can more stably guide the spotting plate 9100 to extend into the cavity 2120. The positioning portion 2220 can position the spotting plate 9100 extending into the cavity 2120, so as to ensure that the spotting plate 9100 is in the expected position.

[0053] For example, Figure 5-7 As shown, the positioning portion 2220 can be constructed to extend from the opening 2110 to the cavity 2120 through the edge of the insertion port 2211. The bottom of the positioning portion 2220 can be suspended. When the spot plate 9100 extends into the cavity 2120, it can be at least partially attached to the positioning portion 2220 to extend into the cavity 2120. Therefore, such a placement rack 2200 can better position the spot plate 9100, so as to better guide the spot plate 9100 to extend into the cavity 2120. After a plurality of different developing agents enter the cavity 2120 through a plurality of liquid inlet tubes 2300 according to a predetermined ratio, the bottom of the positioning portion 2220 is suspended, which can prevent the positioning portion 2220 from having an adverse effect on the mixing of the developing agents in the cavity 2120, and can also prevent the positioning portion 2220 from having an adverse effect on the deployment of the spot plate 9100 in the display cylinder 2100.

[0054] For example, the positioning portion 2220 may have a structure that limits the height direction of the spot plate 9100 to be parallel to the developing agent in the cavity 2120. In this way, after the spot plate 9100 is set in the cavity 2120, it may be parallel to the height direction of the developing agent in the cavity 2120. For example, the spot plate 9100 may be attached to the positioning portion 2220. Such a placement rack 2200 has a simpler structure, so that the overall structure of the display cylinder device 2000 is simpler and easier to implement.

[0055] For example, Figure 2-6 As shown, the spotting plate 9100 may have a spotting plate first end 9101 close to the opening 2110 and a spotting plate second end (not shown due to angle issues) away from the opening 2110. The positioning portion 2220 may limit the spotting plate 9100 to gradually move away from the positioning portion 2220 from the spotting plate first end 9101 to the spotting plate second end. After the spotting plate 9100 is disposed in the cavity 2120, the spotting plate first end 9101 of the spotting plate 9100 may be located above the spotting plate second end. The positioning portion 2220 can limit the spotting plate 9100 to gradually move away from the positioning portion 2220 from the first end 9101 of the spotting plate to the second end of the spotting plate in any suitable manner. For example, an inclined limiting member can be provided on the positioning portion 2220, and the spotting plate 9100 can be abutted against the limiting member. The inclination direction of the limiting member is such that the spotting plate 9100 abutting against the limiting member gradually moves away from the positioning portion 2220 from the first end 9101 of the spotting plate to the second end of the spotting plate. The spotting plate 9100 gradually moves away from the positioning portion 2220 from the first end 9101 of the spotting plate to the second end of the spotting plate. Such a spotting plate 9100 is inclined, and the direction of the supporting force on the liquid on the spotting plate 9100 is more conducive to the spreading of the developing agent on the spotting plate 9100, so that in such a cylinder display device 2000, the effect of the spotting plate 9100 being deployed can be better.

[0056] For example, Figure 2-6As shown, the positioning portion 2220 may be provided with positioning grooves 2221 with opening directions opposite to each other and both facing the center of the cavity 2120. The spotting plate 9100 inserted into the cavity 2120 through the insertion port 2211 may extend into the positioning groove 2221 and be positioned through the positioning groove 2221. The positioning groove 2221 may have any suitable form, and only a portion of the spotting plate 9100 may pass through the positioning groove 2221. For example, in the embodiment shown in the figure, only two side edges of the spotting plate 9100 extend into the positioning groove 2221. The spotting plate 9100 extending into the cavity 2120 may first pass through the insertion port 2211, then pass through the opening 2110, and finally pass through the positioning groove 2221. By designing the extension direction of the positioning groove 2221, the extending direction of the spotting plate 9100 when passing through the positioning groove 2221 can be positioned, so that the inclined direction of the spotting plate 9100 after extending into the cavity 2120 can be positioned. Moreover, after the spotting plate 9100 extends into the positioning groove 2221, the positioning groove 2221 can fix the position of the spotting plate 9100, and at least the portion of the spotting plate 9100 that passes through the positioning groove 2221 will maintain a constant relative position with the positioning groove 2221. By providing the positioning groove 2221, the spotting plate 9100 disposed in the cavity 2120 will be more stable, and the positioning groove 2221 can position the spotting plate 9100, so that the spotting plate 9100 disposed in the cavity 2120 can be tilted in a desired direction.

[0057] For example, Figure 3 As shown, the liquid discharge pipe 2400 and the multiple liquid inlet pipes 2300 can both extend from the opening 2110 into the cavity 2120. When the liquid discharge pipe 2400 and the multiple liquid inlet pipes 2300 both extend from the opening 2110 into the cavity 2120, it is not necessary to open a hole on the exhibition cylinder 2100 to connect with the liquid discharge pipe 2400 and the multiple liquid inlet pipes 2300, so that the sealing performance of the overall device is better, and the developing agent in the cavity 2120 is not easy to leak out.

[0058] For example, Figure 2-3 As shown, the positioning portion 2220 can separate the spot plate 9100 from the drainage tube 2400, and can separate the spot plate 9100 from the plurality of liquid inlet tubes 2300. In such a display tank device 2000, the spot plate 9100 can be prevented from being interfered by the drainage tube 2400 and the plurality of liquid inlet tubes 2300 when being deployed, so that the deployment effect of the spot plate 9100 in such a display tank device 2000 can be better.

[0059] For example, a blowing member (not shown) for blowing air to the spotting plate 9100 in the cavity 2120 may be provided in the cavity 2120. The blowing member may blow air to the spotting plate 9100 in the cavity 2120, so that the deployment efficiency of the spotting plate 9100 may be higher and the deployment effect may be better.

[0060] For example, Figure 7 As shown, the display cylinder device 2000 may include multiple display cylinder groups, each display cylinder group may include two display cylinders 2100, and the two display cylinders 2100 in each display cylinder group may be connected by a display cylinder connector 2500, and the display cylinder connector 2500 may fix the relative position between the two display cylinders 2100. Such a display cylinder device 2000 can simultaneously unfold multiple spotting plates 9100, and the overall unfolding efficiency is higher. The two display cylinders 2100 in each display cylinder group are connected by the display cylinder connector 2500, and the relative positions will not change, and the overall stability can be more stable.

[0061] For example, see Figure 6 , the two exhibition cylinders 2100 in each exhibition cylinder group may be provided with a blowing member (not shown in the figure) for blowing air to the spotting plate 9100 located in the cavity 2120, and the exhibition cylinder connecting member 2500 may be provided with a baffle 2510, which may be located between the two exhibition cylinders 2100 and may separate the two exhibition cylinders 2100, and the top of the baffle 2510 may not be lower than the opening 2110. The baffle 2510 may prevent the blowing member provided in the exhibition cylinder 2100 from interfering with another exhibition cylinder 2100 in the same exhibition cylinder group, so that the deployment effect of the spotting plate 9100 in the two exhibition cylinders 2100 in each exhibition cylinder group can be better, so that the deployment effect of the spotting plate 9100 in such an exhibition cylinder device 2000 can be better.

[0062] For example, Figure 2-4 As shown, the cylinder display device 2000 may include a cover assembly 2600, and the cover assembly 2600 may include a cover 2610 and a cover driver 2620. The cover 2610 may be away from the opening 2110 or cover the opening 2110 under the action of the cover driver 2620. The cover driver 2620 may control the cover 2610 to cover the opening 2110 when necessary. For example, when the spotting plate 9100 does not need to be unfolded, the cover 2610 may cover the opening 2110 under the action of the cover driver 2620 to prevent the cavity 2120 from being polluted by the external environment. When the spotting plate 9100 needs to be unfolded, the cover 2610 may be away from the opening 2110 under the action of the cover driver 2620, so that the spotting plate 9100 can extend into the cavity 2120 through the opening 2110.

[0063] For example, Figure 2-4As shown, the exhibition cylinder 2100 may include a frame 2130 and a bottom plate opposite to the opening 2110, and the frame 2130 and the bottom plate may enclose a cavity 2120. The frame 2130 may include an observation surface 2131, and at least the observation surface 2131 of the frame 2130 is transparent. The frame 2130 may be made entirely of transparent materials, or only the observation surface 2131 may be transparent. The exhibition cylinder device 2000 may also include an exhibition cylinder image acquisition component 2700, and the exhibition cylinder image acquisition component 2700 may be in any suitable form. The exhibition cylinder image acquisition component 2700 may collect the expansion status of the spot sample plate 9100 in the cavity 2120 through the observation surface 2131. The unfolding condition of the spotting plate 9100 can be observed through the unfolding cylinder image acquisition component 2700, so that timely adjustments can be made when problems occur in the unfolding of the spotting plate 9100, and the spotting plate 9100 can also be taken out in time after the unfolding of the spotting plate 9100 is completed. Such an unfolding cylinder device 2000 as a whole is more efficient in unfolding the spotting plate 9100 and has a better unfolding effect.

[0064] For example, Figure 8-12 As shown, the spotting device 1000 may include a spotting frame 1100 , a driving component 1200 , and a spotting component 1300 .

[0065] The sample spotting frame 1100 can be fixed to a device such as the ground or a table, so that it can serve as the base of the sample spotting device 1000. The structure of the sample spotting frame 1100 can be arbitrary. The main body of the driving component 1200 can be set on the sample spotting frame 1100. The driving component 1200 includes but is not limited to a motor driving component, a cylinder driving component and / or an electric cylinder driving component. The sample spotting component 1300 may include a sample spotting needle 1310 and a gland 1320. The sample spotting needle 1310 and the gland 1320 can be connected to the driving end of the driving component 1200 respectively. The sample spotting needle 1310 can adopt various types of sample spotting needles known in the art or that may appear in the future, such as a high-precision micro-sample spotting needle. The gland 1320 can have a perforation 1321. Under the drive of the driving component 1200, the sample spotting needle 1310 can be raised and lowered along the perforation 1321. The driving component 1200 can be configured to: after driving the capping member 1320 to press the bottle cap of the spotting bottle, drive the spotting needle 1310 to pass through the through hole 1321 and extend into the spotting bottle, and absorb the spotting liquid in the spotting bottle. After the spotting needle 1310 completes the liquid absorption, the driving component 1200 can drive the spotting needle 1310 to pass through the through hole 1321 and detach from the spotting bottle, and then drive the capping member 1320 to detach from the bottle cap of the spotting bottle. The spotting needle 1310 can always be inserted in the through hole 1321, and can also detach from the through hole 1321 during the lifting process.

[0066] In actual application of the spotting device 1000, the spotting assembly 1300 can be located above the spotting bottle. Then, the driving assembly 1200 can drive the capping member 1320 to descend to press the bottle cap of the spotting bottle, so that the spotting bottle can be fixed. Then, the driving assembly 1200 can drive the spotting needle 1310 to descend, so that the spotting needle 1310 can pass through the outlet hole 1321, so that it can extend into the spotting bottle, and then absorb the spotting liquid in the spotting bottle. The capping member 1320 and the spotting needle 1310 can descend at the same time, or they can descend in sequence, as long as the capping member 1320 can press the bottle cap of the spotting bottle before the spotting needle 1310 extends into the spotting bottle to absorb liquid. When the spotting needle 1310 has completed the liquid absorption, the driving assembly 1200 can drive the spotting needle 1310 to rise, so that it can pass through the outlet hole 1321 and leave the spotting bottle. Then, the driving assembly 1200 can drive the capping member 1320 to rise, so that the cap of the spotting bottle can be separated, and the fixation of the spotting bottle can be cancelled. When spotting, the spotting assembly 1300 can be located above the spotting plate 9100. Then, the driving assembly 1200 can drive the spotting needle 1310 to rise, fall or remain stationary, so that the spotting needle 1310 and the spotting plate 9100 have a desired height difference. Then, the spotting assembly 1300 can drive the spotting needle 1310 to spot the spotting liquid it absorbs onto the spotting plate 9100.

[0067] In the process of the driving component 1200 driving the sample spotting needle 1310 to disengage from the sample spotting bottle, since the driving component 1200 drives the capping member 1320 to press the bottle cap of the sample spotting bottle, even if the sample spotting needle 1310 rubs against the bottle cap of the sample spotting bottle during the disengagement process, the capping member 1320 can keep the sample spotting bottle still. In this way, the sample spotting needle 1310 will not move with the sample spotting bottle. Therefore, the sample spotting needle 1310 can smoothly perform subsequent sample spotting operations, the sample spotting device 1000 has high reliability, and the user experience is good. In addition, the fixed sample spotting bottle will not be damaged, and the sample spotting device 1000 has high safety. In addition, in the process of the sample spotting needle 1310 extending into the sample spotting bottle and absorbing the sample spotting liquid in the sample spotting bottle, the sample spotting bottle can also remain fixed under the pressure of the capping member 1320, so as not to affect the sample spotting needle 1310 to perform the operation.

[0068] For example, Figure 9-11As shown, the spotting needle 1310 may include a needle tube 1311, a needle 1312 and a piston rod 1313. The needle 1312 may be connected to the lower end of the needle tube 1311. The piston rod 1313 may be movably inserted into the upper end of the needle tube 1311. The driving end of the drive assembly 1200 may be connected to the piston rod 1313, so that the piston rod 1313 may be driven to rise and fall in the needle tube 1311, so that the spotting needle 1310 may aspirate liquid and spot samples. Specifically, under the drive of the drive assembly 1200, the needle 1312 may descend along the through hole 1321, so that it may extend into the spotting bottle. Then, the drive assembly 1200 may drive the piston rod 1313 to rise, so that the spotting liquid in the spotting bottle may be aspirated through the needle 1312. After the spotting needle 1310 completes the liquid aspiration, the drive assembly 1200 can drive the needle 1312 to rise along the outlet hole 1321, so that it can pass through the outlet hole 1321 and leave the spotting bottle. When spotting, the drive assembly 1200 can drive the piston rod 1313 to descend, so that the spotting liquid can be spotted on the spotting plate through the needle 1312. The needle 1312 can be integrally connected to the lower end of the needle tube 1311 by any suitable method such as welding, bonding or injection molding. In this way, the connection strength between the needle 1312 and the needle tube 1311 is relatively high, especially for the needle 1312 of the micro-spotting needle, which has a small diameter, so it is particularly important to improve the connection strength with the needle tube 1311. In addition, compared with the detachable connection method between the needle tube and the needle, this solution can avoid the deviation of the position of the needle 1312 due to installation error, thereby affecting the aspiration and spotting.

[0069] Exemplarily, the spotting needle 1310 may include multiple ones, including but not limited to the two shown in the figure, for example, three or more. The driving component 1200 can drive multiple spotting needles 1310, so that each spotting needle 1310 can absorb the spotting liquid in the spotting bottle one by one, and spot the sample to the spotting plate 9100 one by one. With such an arrangement, the spotting component 1300 has a high working efficiency in aspirating and spotting. Multiple spotting needles 1310 can be arranged in a horizontal direction. Multiple spotting needles 1310 can correspond to a capping member 1320, and the capping member 1320 can press the bottle caps of multiple spotting bottles at the same time. Alternatively, multiple spotting needles 1310 can correspond to the capping member 1320 one by one, and each capping member 1320 can press the bottle cap of its corresponding spotting bottle.

[0070] For example, Figure 8As shown, the sample spotting device 1000 may also include a first horizontal driving member 1110 and a second horizontal driving member 1120. The driving end of the first horizontal driving member 1110 may be connected to the main body of the driving assembly 1200. Under the drive of the first horizontal driving member 1110, the driving assembly 1200 and the sample spotting assembly 1300 may move along the first horizontal direction. The main body of the second horizontal driving member 1120 may be arranged on the sample spotting frame 1100. The driving end of the second horizontal driving member 1120 may be connected to the main body of the first horizontal driving member 1110. Under the drive of the second horizontal driving member 1120, the first horizontal driving member 1110, the driving assembly 1200 and the sample spotting assembly 1300 may move along the second horizontal direction. The second horizontal direction may be perpendicular to the first horizontal direction. The first horizontal driving member 1110 includes but is not limited to a motor, a cylinder or an electric cylinder. The second horizontal driving member 1120 includes but is not limited to a motor, a cylinder or an electric cylinder. With the cooperation of the first horizontal driving member 1110 and the second horizontal driving member 1120, the driving assembly 1200 and the sample spotting assembly 1300 can move in the first horizontal direction and the second horizontal direction, so that they can move to any suitable position in the horizontal direction. Exemplarily, the first horizontal driving member 1110 and the second horizontal driving member 1120 can drive the sample spotting assembly 1300 to move above the sample spotting bottle so that the sample spotting needle 1310 can aspirate liquid. When the aspiration is completed, the first horizontal driving member 1110 and the second horizontal driving member 1120 can drive the sample spotting assembly 1300 to move above the sample spotting plate 9100 so that the sample spotting needle 1310 can spot the sample spotting plate 9100. Compared with the use of driving members such as manipulators, the first horizontal driving member 1110 and the second horizontal driving member 1120 can accurately control the position of the sample spotting assembly 1300, thereby improving the accuracy of aspiration and spotting of the sample spotting needle 1310.

[0071] For example, Figure 9-11As shown, the drive assembly 1200 may include a first drive member 1210, a second drive member 1220, and a third drive member 1230. The drive end of the first drive member 1210 may be connected to the capping member 1320 to drive the capping member 1320 to rise and fall, so that the bottle cap of the sample bottle can be pressed and separated. The drive end of the second drive member 1220 may be connected to the main body of the sample needle 1310 (including the needle tube 1311 and / or the needle 1312) to drive the sample needle 1310 to rise and fall as a whole, so that it can pass through the hole 1321 and extend into and out of the sample bottle. The drive end of the third drive member 1230 may be connected to the piston rod 1313 of the sample needle 1310 to drive the piston rod 1313 to rise and fall, so that liquid aspiration and sample spotting can be performed. The first drive member 1210 includes but is not limited to a motor, a cylinder, or an electric cylinder. The second drive member 1220 includes but is not limited to a motor, a cylinder, or an electric cylinder. The third drive member 1230 includes but is not limited to a motor, a cylinder, or an electric cylinder. Specifically, the first driving member 1210 can drive the capping member 1320 to descend to press the bottle cap of the sample spotting bottle. Then, the second driving member 1220 can drive the sample spotting needle 1310 to descend so that the sample spotting needle 1310 can pass through the hole 1321 and thus can extend into the sample spotting bottle. Then, the third driving member 1230 can drive the piston rod 1313 of the sample spotting needle 1310 to rise so that the sample spotting liquid in the sample spotting bottle can be absorbed. When the sample spotting needle 1310 has completed the liquid absorption, the second driving member 1220 can drive the sample spotting needle 1310 to rise so that it can pass through the hole 1321 and detach from the sample spotting bottle. Then, the first driving member 1210 can drive the capping member 1320 to rise so that it can detach from the bottle cap of the sample spotting bottle. When sample spotting is required, the first driving member 1210 and / or the second driving member 1220 can drive the sample spotting needle 1310 to have a desired height difference with the sample spotting plate 9100. Then, the third driving member 1230 can drive the piston rod 1313 of the spotting needle 1310 to descend, so that the spotting liquid can be spotted onto the spotting plate 9100. With such a configuration, the structure of the driving assembly 1200 is relatively simple and easy to manufacture.

[0072] When the spotting needle 1310 is aspirating, the distance it descends will determine the length of the spotting needle 1310 extending into the spotting bottle, thereby determining the maximum amount of spotting liquid that can be aspirated. In addition, the distance the piston rod 1313 rises will determine the amount of spotting liquid aspirated.

[0073] When the spotting needle 1310 is spotting, and the height difference between it and the spotting plate 9100 is greater than the expected height difference, the spotting liquid may not be spotted to the spotting plate 9100, or the spotting effect may not be as expected. When the height difference between the spotting needle 1310 and the spotting plate 9100 is less than the expected height difference, the spotting needle 1310 may contact the spotting plate 9100, thereby causing damage to both. Therefore, by accurately controlling the position of the spotting needle 1310 so that the spotting needle 1310 and the spotting plate 9100 have the expected height difference, the spotting effect can be improved. In addition, the distance that the piston rod 1313 descends will determine the amount of spotting liquid spotted.

[0074] For example, Figure 8-11As shown, the main body of the first driving member 1210 can be directly or indirectly disposed on the spotting frame 1100. In the embodiment where the spotting device 1000 includes the first horizontal driving member 1110 and the second horizontal driving member 1120, the main body of the first driving member 1210 can be disposed on the driving end of the first horizontal driving member 1110. The driving end of the first driving member 1210 can be connected to the main body of the second driving member 1220, the main body of the third driving member 1230, and the gland member 1320, so as to drive the second driving member 1220, the third driving member 1230, the spotting needle 1310, and the gland member 1320 to rise and fall synchronously. The driving end of the second driving member 1220 can be connected to the main body of the third driving member 1230 and the main body of the spotting needle 1310, so as to drive the third driving member 1230 and the spotting needle 1310 to rise and fall synchronously. With such arrangement, the first driving member 1210 can simultaneously drive the second driving member 1220, the third driving member 1230, the sample spotting needle 1310 and the capping member 1320 to descend so as to approach the sample spotting bottle. After the capping member 1320 presses the bottle cap of the sample spotting bottle, the second driving member 1220 can drive the third driving member 1230 and the sample spotting needle 1310 to descend so that the sample spotting needle 1310 can extend into the sample spotting bottle. Then, the third driving member 1230 can drive the piston rod 1313 of the sample spotting needle 1310 to rise so as to absorb the sample spotting liquid in the sample spotting bottle. After the sample spotting needle 1310 has completed the liquid absorption, the second driving member 1220 can drive the third driving member 1230 and the sample spotting needle 1310 to rise so as to separate the sample spotting needle 1310 from the sample spotting bottle. Then, the first driving member 1210 can drive the second driving member 1220, the third driving member 1230, the sample spotting needle 1310 and the capping member 1320 to rise, so that the capping member 1320 can be separated from the bottle cap of the sample spotting bottle. In this way, the driving assembly 1200 can achieve multi-stage driving, thereby reducing energy waste. In addition, the stroke of the second driving member 1220 and the third driving member 1230 driving the sample spotting needle 1310 and the piston rod 1313 to rise and fall can be relatively short, so that it is convenient to accurately control the position of the sample spotting needle 1310 and the piston rod 1313 by adopting a high-precision structure, and then accurately control the amount of liquid aspirated. When spotting is required, the first driving member 1210 and the second driving member 1220 can choose whether to start according to the position of the sample spotting plate 9100. Exemplarily, when the height difference between the spotting needle 1310 and the spotting plate 9100 is much greater than the expected height difference, the first driving member 1210 can simultaneously drive the second driving member 1220, the third driving member 1230, the spotting needle 1310 and the capping member 1320 to descend. Then, the second driving member 1220 can drive the third driving member 1230 and the spotting needle 1310 to descend, so that the spotting needle 1310 has the expected height difference with the spotting plate 9100. Then, the third driving member 1230 can drive the piston rod 1313 of the spotting needle 1310 to descend, so that the spotting liquid can be spotted on the spotting plate 9100.When the height difference between the spotting needle 1310 and the spotting plate 9100 is slightly greater than the expected height difference, the first driving member 1210 may not need to be started. The second driving member 1220 may drive the third driving member 1230 and the spotting needle 1310 to descend so that the spotting needle 1310 is close to the spotting plate 9100. Then, the third driving member 1230 may drive the piston rod 1313 of the spotting needle 1310 to descend, so that the spotting liquid can be sampled on the spotting plate 9100. Exemplarily, when the spotting needle 1310 has an expected height difference with the spotting plate 9100, both the first driving member 1210 and the second driving member 1220 may not need to be started. The third driving member 1230 may directly drive the piston rod 1313 of the spotting needle 1310 to descend, so that the spotting liquid can be sampled on the spotting plate 9100. Of course, if the height difference between the spotting needle 1310 and the spotting plate 9100 is smaller than the expected height difference, the first driving member 1210 and / or the second driving member 1220 may also drive the spotting needle 1310 to rise, ultimately making the spotting needle 1310 and the spotting plate 9100 have the expected height difference.

[0075] For example, Figure 9-11 As shown, the driving assembly 1200 may further include a first connecting frame 1240, a second connecting frame 1250, a third connecting frame 1260, a first slide rail 1270 and a second slide rail 1280. The first connecting frame 1240 may be connected between the sample spotting frame 1100 and the main body of the first driving member 1210. In the embodiment where the sample spotting device 1000 includes the first horizontal driving member 1110 and the second horizontal driving member 1120, the first connecting frame 1240 may be connected between the driving end of the first horizontal driving member 1110 and the main body of the first driving member 1210. The first slide rail 1270 may be disposed on the first connecting frame 1240. The second connecting frame 1250 may be connected between the driving end of the first driving member 1210 and the main body of the second driving member 1220. Furthermore, the second connecting frame 1250 may be slidably connected to the first slide rail 1270. The capping member 1320 and the second slide rail 1280 may be disposed on the second connecting frame 1250. The third connecting frame 1260 may be connected between the driving end of the second driving member 1220 and the main body of the third driving member 1230. In addition, the third connecting frame 1260 may be slidably connected to the second slide rail 1280. The main body of the spotting needle 1310 may be disposed on the third connecting frame 1260. By providing the first slide rail 1270 and the second slide rail 1280, the stability and linearity of the lifting and lowering of the capping member 1320 and the spotting needle 1310 may be improved.

[0076] For example, Figure 9-11As shown, the driving assembly 1200 may further include a first lead screw 1291 and a first nut 1292. The driving end of the second driving member 1220 may be connected to the first lead screw 1291 to drive the first lead screw 1291 to rotate. The first nut 1292 may be connected to the third connecting frame 1260. In addition, the first lead screw 1291 may be threadedly connected to the first lead screw 1291. The second driving member 1220 may drive the first lead screw 1291 to rotate, thereby driving the first nut 1292 to rise and fall along the extension direction of the first lead screw 1291, and further driving the third connecting frame 1260 and the spotting needle 1310 connected to the third connecting frame 1260 to rise and fall. By providing the first lead screw 1291 and the first nut 1292, the position of the spotting needle 1310 may be accurately controlled, and the stability of the rise and fall of the spotting needle 1310 is high. In this way, the spotting needle 1310 has a high precision in aspirating and spotting.

[0077] For example, Figure 9-11 As shown, the drive assembly 1200 may also include a second lead screw 1293 and a second nut 1294. The driving end of the third drive member 1230 may be connected to the second lead screw 1293 to drive the second lead screw 1293 to rotate. The second nut 1294 may be connected to the piston rod 1313 of the spotting needle 1310 directly or through other components. In addition, the second nut 1294 may be threadedly connected to the second lead screw 1293. The third drive member 1230 may drive the second lead screw 1293 to rotate, thereby driving the piston rod 1313 to rise and fall. By setting the second lead screw 1293 and the second nut 1294, the position of the piston rod 1313 may be accurately controlled, and the stability of the rise and fall of the piston rod 1313 is high. In this way, the precision of the spotting needle 1310 in aspirating and spotting is high.

[0078] For some spotting bottles, the bottle caps are usually provided with through holes. The through holes may be covered with a sealing layer to prevent the spotting liquid in the spotting bottle from volatilizing or spilling during transportation. The structure of the sealing layer may be arbitrary. In some embodiments, the sealing layer may be made of elastic materials such as silicone. The sealing layer may be provided with a gap in the shape of a letter or a cross. Usually, the sealing layer can close the gap by its own elasticity.

[0079] For example, Fig. 9 and 12As shown, the capping member 1320 may include a capping plate 1324 and an expanded boss 1322. The expanded boss 1322 may protrude downward from the capping plate 1324. The through hole 1321 may successively penetrate the capping plate 1324 and the expanded boss 1322. The drive assembly 1200 may be connected to the capping plate 1324 and / or the expanded boss 1322. The drive assembly 1200 may be used to drive the capping plate 1324 to press and disengage the bottle cap. Furthermore, the drive assembly 1200 may be used to drive the expanded boss 1322 to expand the sealing layer on the bottle cap to separate the sealing layer from the spotting needle 1310. Specifically, as the drive assembly 1200 drives the capping member 1320 to descend, the expanded boss 1322 may be driven to expand the sealing layer, and then the capping plate 1324 may press the bottle cap. Since the spotting needle 1310 passes through the hole 1321, the spotting needle 1310 will not contact the sealing layer under the action of the expansion boss 1322, so that the structure of the sealing layer will not be damaged due to the expansion. In particular, for the above-mentioned sealing layer with a gap, if the expansion boss 1322 is not provided, when the spotting needle 1310 expands the gap, the sealing layer will always be against the spotting needle 1310 due to the elastic effect. In this way, when the spotting needle 1310 rises and leaves the spotting bottle, the sealing layer will scrape off the spotting liquid on the spotting needle 1310, resulting in a reduction in the spotting liquid that is already absorbed, and then resulting in a decrease in the spotting effect. By providing the expansion boss 1322, the sealing layer will not contact the spotting needle 1310, and the spotting needle 1310 can absorb the expected amount of spotting liquid.

[0080] For example, Fig.12 As shown, the outer edge of the cover pressing plate 1324 may have a positioning boss 1323 protruding downward. Before the cover pressing plate 1324 presses the bottle cap, the driving assembly 1200 may drive the positioning boss 1323 to preferentially sleeve the top of the bottle cap. The positioning boss 1323 may be annular or arc-shaped. By providing the positioning boss 1323, the bottle cap may be pre-positioned, so that the cover pressing plate 1324 may accurately press the bottle cap of the spotting bottle, and the spotting needle 1310 may accurately extend into the spotting bottle.

[0081] For example, Figure 9-11As shown, the spotting device 1000 may also include an elastic component 1400. The elastic component 1400 may include a pressure rod 1410 and an elastic member 1420. The upper end of the elastic member 1420 may be connected to the driving end of the driving component 1200. In the embodiment where the driving component 1200 includes a first driving member 1210, a second driving member 1220 and a third driving member 1230, the upper end of the elastic member 1420 may be connected to the first driving member 1210. The lower end of the elastic member 1420 may be connected to the pressure rod 1410. The driving component 1200 may be used to drive the pressure rod 1410 to rise and fall, so that the bottle cap can be pressed and disengaged. The pressure rod 1410 may protrude downward from the expansion boss 1322. Under the drive of the driving component 1200, the pressure rod 1410 may press the bottle cap, and as it continues to descend, the pressure rod 1410 may compress the elastic member 1420, so that it can move relatively toward the expansion boss 1322. As it continues to descend, the expanded boss 1322 can expand the sealing layer. On the contrary, when the drive assembly 1200 drives the expanded boss 1322 to rise and detach from the sealing layer, the elastic member 1420 can release elastic potential energy to drive the pressure rod 1410 to move relative to the expanded boss 1322, so that the bottle cap can be continuously pressed. If the elastic member 1400 is not provided, the expanded boss 1322 will rub against the sealing layer during the process of detaching from the sealing layer, thereby driving the sample spotting bottle to move. The elastic member 1400 can make the pressure rod 1410 continue to press the bottle cap to prevent the sample spotting bottle from moving. As it continues to rise, when the pressure rod 1410 detaches from the bottle cap, the elastic member 1420 can completely release elastic potential energy, so that the pressure rod 1410 can be driven to protrude downward from the expanded boss 1322 for use next time. The elastic member 1420 includes but is not limited to an elastic member made of elastic materials such as springs or silicone.

[0082] For example, Figure 9-11 As shown, the pressing rod 1410 may include a pressing portion 1411 and an extension rod 1412. The extension rod 1412 may extend upward from the pressing portion 1411. The elastic member 1420 may be sleeved on the extension rod 1412. Furthermore, the lower end of the elastic member 1420 may be connected to the pressing portion 1411. The pressing portion 1411 may be used to press and disengage the bottle cap. With such an arrangement, the structure of the elastic assembly 1400 is relatively compact and occupies less space. Furthermore, the extension rod 1412 may also guide the elastic member 1420 to prevent the elastic member 1420 from disengaging from the expected position.

[0083] For example, Fig.12As shown, a pressure rod through hole 1325 may be provided on the pressure cover plate 1324. The extension rod 1412 may pass through the pressure rod through hole 1325. With such a configuration, the structure of the pressure cover member 1320 and the elastic component 1400 is relatively compact and occupies less space. In addition, the pressure rod through hole 1325 may also guide the extension rod 1412 to prevent the extension rod 1412 from being out of the expected position.

[0084] Exemplarily, the spotting device 1000 may also include a spotting platform and a positioning assembly. A groove may be provided on the spotting platform. The groove may be used to place the spotting plate 9100. The positioning assembly may be used to position the spotting plate 9100 in the groove. The structure of the positioning assembly may be arbitrary, for example, it may be a suction cup. In some embodiments, the positioning assembly may include a plurality of cylinder driving members, and the plurality of cylinder driving members may drive the spotting plate 9100 in the groove to move so as to position the spotting plate 9100. The driving assembly 1200 may be used to drive the spotting needle 1310 to spot the spotting plate 9100. With such a configuration, the spotting device 1000 may also perform spotting operations, and its functions are more abundant.

[0085] Exemplarily, the spotting device 1000 may also include a spotting plate detector and a controller. The controller may be electrically connected to the spotting plate detector. The spotting plate detector is located on the side of the spotting plate 9100 in the groove. In addition, the spotting plate detector may be used to detect the height of the non-transparent top surface of the spotting plate 9100 tilted downward to generate and send a signal to the controller. Generally speaking, the spotting plate 9100 may include a transparent body at the bottom and a coating on the top of the transparent body. The transparent body may be made of glass or other materials to facilitate photography. The coating may include a silicone coating, etc. The top surface of the coating may be a non-transparent top surface. The developing agent and the spotting liquid may be attached to the non-transparent top surface. When the driving component 1200 drives the spotting needle 1310 to spot, the controller may be used to make the spotting needle 1310 have an expected height difference with the non-transparent top surface based on the signal. The spotting plate detector may use various types of spotting plate detectors known in the art or that may appear in the future, including but not limited to laser sensors or infrared sensors. The controller can be built with electronic components such as timers, comparators, registers, digital logic circuits, etc., or it can be implemented using processor chips such as single-chip microcomputers, microprocessors, programmable logic controllers (PLCs), digital signal processors (DSPs), field programmable gate arrays (FPGAs), programmable logic arrays (PLA), application-specific integrated circuits (ASICs), and their peripheral circuits.

[0086] In actual application of the spotting device 1000, the spotting plate detector can send detection light at an angle downward, and the detection light can be reflected back to the spotting plate detector through the non-transparent top surface. In this way, the spotting plate detector can send a signal to the controller. The controller can receive the signal, so that the height of the non-transparent top surface can be calculated. Exemplarily, the controller can use the distance from the non-transparent top surface of the standard spotting plate 9100 to the spotting plate detector as the standard distance, and then can calculate the distance from the spotting plate 9100 currently being detected to the spotting plate detector according to the signal, and then can calculate the height of the non-transparent top surface of the spotting plate 9100 currently being detected by comparison with the standard distance. In this way, when the driving component 1200 drives the spotting needle 1310 to spot, the controller can control the distance of the spotting needle 1310 rising and falling based on the height of the non-transparent top surface, and then can make the spotting needle 1310 have an expected height difference with the non-transparent top surface. In this way, the spotting effect can be improved.

[0087] Due to manufacturing errors, the heights of different spotting plates 9100 may be different. The height of the non-transparent top surface of the spotting plate 9100 is calculated by the spotting plate detector and the controller, so that the spotting effect of the spotting needle 1310 can be better. In this way, the differences in the spotting plate 9100 will not lead to a worse spotting effect. In addition, since the spotting plate detector is located on the side of the spotting plate 9100 in the groove, it can avoid the space above the spotting plate 9100, so as to facilitate the spotting of the spotting needle 1310, as well as the placement and removal of the spotting plate 9100.

[0088] Exemplarily, the spotting device 1000 may further include a reference check block. After the spotting needle 1310 is replaced, the drive assembly 1200 may be used to drive the lower end of the spotting needle 1310 to contact the reference check block, so that the position of the spotting needle 1310 is used as the reference position. In this way, the drive assembly 1200 may drive the spotting needle 1310 to rise and fall at the reference position. In this way, even if there is an installation error when the spotting needle 1310 is replaced, the position of the spotting needle 1310 can still be accurately controlled.

[0089] See also Figure 13-15 The color developing device 4000 may include a heating color developing device 4100. The heating color developing device 4100 may include a heater 4200 and a storage table 4300. The storage table 4300 may have a working surface 4310 on which the spotting plate 9100 may be placed. Fig.16A and Fig. 16B, a cavity 4340 may be formed inside the storage table 4300, and the cavity 4340 may be connected to the heater 4200 through the first heating channel 4400, and the first heating channel 4400 may be a pipe or any other suitable form. The heater 4200 may be a hot air gun or any other suitable form. Hot air may be formed at the heater 4200, and the hot air may flow to the cavity 4340 through the first heating channel 4400. The cavity 4340 may extend to form a second heating channel 4320 and a third heating channel 4330 on opposite sides in the first direction (direction XX in the figure). A first air outlet 4321 may be formed on the end of the second heating channel 4320 away from the cavity 4340, and a second air outlet 4331 may be formed on the end of the third heating channel 4330 away from the cavity 4340, and the first air outlet 4321 and the second air outlet 4331 may both be arranged toward the working surface 4310. The first air outlet 4321 and the second air outlet 4331 can blow air toward the working surface 4310. The working surface 4310 may include a portion made of a metal material that is easy to conduct heat. The hot air flowing to the cavity 4340 through the first heating channel 4400 can, on the one hand, heat the cavity 4340, thereby increasing the temperature of the working surface 4310, and thus heating the spotting plate 9100 placed on the working surface 4310; on the other hand, the hot air can enter the second heating channel 4320 and the third heating channel 4330 respectively through the cavity 4340, and then can flow out hot air from the first air outlet 4321 and the second air outlet 4331 respectively, and the hot air flowing out from the first air outlet 4321 and the second air outlet 4331 respectively can heat the spotting plate 9100 located on the working surface 4310.

[0090] The heating color developing device 4100 provided by the present invention can heat up the working surface 4310 of the storage table 4300 through the first heating channel 4400 after turning on the heater 4200, so as to heat the spotting plate 9100 placed on the working surface 4310. In addition, after turning on the heater 4200, hot air can be formed from the first air outlet 4321 and the second air outlet 4331 to blow toward the spotting plate 9100 placed on the working surface 4310, so as to heat the spotting plate 9100. Such a heating color developing device 4100 can automatically heat the spotting plate 9100 placed on the working surface 4310, with a higher degree of automation, and can avoid the problems of low efficiency of manual operation and poor experimental effect during the heating of the spotting plate 9100.

[0091] In one embodiment of the present invention, see Figure 13-15, the second heating channel 4320, the third heating channel 4330 and the working surface 4310 can be enclosed to form a limiting groove 4350, and the dot plate 9100 can be placed in the limiting groove 4350. Exemplarily, the first air outlet 4321 and / or the second air outlet 4331 can be higher than the dot plate 9100. In such a heating color development device 4100, the dot plate 9100 is placed in the limiting groove 4350, which can make the position of the dot plate 9100 more stable, so that the overall device can be more stable. Moreover, when the dot plate 9100 is placed on the working surface 4310, the working surface 4310 can be positioned by the limiting groove 4350, so that placing the dot plate 9100 on the working surface 4310 can be simpler and more convenient.

[0092] In one embodiment of the present invention, see Fig.13 , a connecting plate 4360 may be provided on the storage platform 4300, and an opening may be provided on the connecting plate 4360, and the first heating channel 4400 may be connected to the cavity 4340 through the opening, and a heat insulating member 4500 may be provided on at least one side of the connecting plate 4360 in a second direction (direction YY in the figure) perpendicular to the first direction XX. The connecting plate 4360 may be formed by integrated processing with the heat insulating member 4500, in which case the connecting plate 4360 may be a side plate of the heat insulating member 4500; the connecting plate 4360 may also be separately processed from the heat insulating member 4500 and connected together by welding, threaded connection or any other suitable form, in which case the connecting plate 4360 may be a separate plate or any other suitable structure. The provision of the connecting plate 4360 may provide better support for the storage platform 4300. Hot air flows in the first heating channel 4400, so the temperature of the outer side of the first heating channel 4400 is usually higher. When the heat insulating member 4500 is provided on the side of the connecting plate 4360 close to the placement table 4300, the setting of the heat insulating member 4500 can prevent the higher temperature from damaging the outer side of the placement table 4300; when the heat insulating member 4500 is provided on the side of the connecting plate 4360 away from the placement table 4300, since the placement table 4300, the connecting plate 4360 and the heat insulating member 4500 are usually arranged in the box body 4700, the setting of the heat insulating member 4500 can prevent the higher temperature from damaging the box body 4700.

[0093] In one embodiment of the present invention, see Fig.17, a storage plate 4600 may be provided on the working surface 4310, and a plurality of support protrusions 4610 protruding away from the working surface 4310 may be provided on the storage plate 4600, and the support protrusions 4610 may protrude perpendicularly to the working surface 4310, or may protrude at a certain angle to the working surface 4310. The support protrusions 4610 may be of any suitable shape and size. A plurality of support protrusions 4610 may surround a positioning area, and the spotting plate 9100 may be placed on the storage plate 4600, and the spotting plate 9100 may be limited in the positioning area. For example, as Fig.17 As shown, the storage plate 4600 may be provided with support protrusions 4610 at four corners, and the four support protrusions 4610 may position the spotting plate 9100, and the four support protrusions 4610 may surround a positioning area, and the four support protrusions 4610 may limit the spotting plate 9100 in the positioning area. In such a heating color developing device 4100, for the positioning area surrounded by multiple support protrusions 4610, since multiple support protrusions 4610 limit the spotting plate 9100, when placing the spotting plate 9100 in the positioning area and taking the spotting plate 9100 out of the positioning area, the spotting plate 9100 can be grabbed from different directions. For example, Fig.17 In the illustrated embodiment, the two opposite sides of the dot plate 9100 along the first direction XX can be grasped to place the dot plate 9100 in the positioning area; when the dot plate 9100 is taken out of the positioning area, the two opposite sides of the dot plate 9100 along the third direction (the illustrated direction ZZ) can be grasped. In this way, when a manipulator or any other form of handling device is used to place the dot plate 9100 in the positioning area on the placement plate 4600, or to take the dot plate 9100 out of the positioning area on the placement plate 4600, it can be clearly observed and determined whether the operation currently being performed is to place the dot plate 9100 or to take out the dot plate 9100. Such a heating color development device 4100 can be more suitable for equipment with a high level of automation.

[0094] For example, see Fig.14 , Fig.15 and Fig.17, a positioning column 4370 may be protruded on the outer surface of the storage table 4300 along the third direction (direction ZZ in the figure), the third direction ZZ is perpendicular to the first direction XX, and the third direction ZZ and the first direction XX are parallel to the plane where the working surface 4310 is located. A mounting plate 4620 may be provided on the storage plate 4600, the mounting plate 4620 may be perpendicular to the third direction ZZ, the mounting plate 4620 may be provided with a mounting through hole 4621, and the positioning column 4370 may be inserted into the mounting through hole 4621. The positioning column 4370 may be inserted into the mounting through hole 4621 by snap connection, simple overlap or other various forms. By inserting the positioning column 4370 into the mounting through hole 4621, the storage plate 4600 can be positioned, and in this way, it can be simpler and more convenient to set the storage plate 4600 on the storage table 4300, and the overall structure can also be simpler.

[0095] In one embodiment of the present invention, there may be a gap between the first air outlet 4321 and the second air outlet 4331. Fig.15 and Fig.16A , there may be a gap C between the first air outlet 4321 and the second air outlet 4331. The heating color development device 4100 may include a heating image acquisition component (not shown in the figure), and the heating image acquisition component may be of any suitable form. The heating image acquisition component may acquire the color development of the dot pattern plate 9100 placed on the working surface 4310 through the gap C. The color development of the dot pattern plate 9100 may be observed through the heating image acquisition component, so that timely adjustments may be made when problems occur in the heating color development of the dot pattern plate 9100, and the dot pattern plate 9100 may be taken out in time after the heating color development of the dot pattern plate 9100 is completed. Such a heating color development device 4100 as a whole may be more efficient in heating and coloring the dot pattern plate 9100.

[0096] In one embodiment of the present invention, the heating color developing device 4100 may include a box 4700, the storage table 4300, the second heating channel 4320 and the third heating channel 4330 may all be located inside the box 4700, the heater 4200 may be located outside the box 4700, and the first heating channel 4400 may pass through a side of the box 4700 and communicate between the storage table 4300 and the heater 4200. The box 4700 may be in any suitable form. The box 4700 may protect the storage table 4300 and the spotting plate 9100 placed on the working surface 4310, so as to prevent the spotting plate 9100 from being disturbed by external environmental factors during the heating color developing process. Such a heating color developing device 4100 may have a better heating color developing effect on the spotting plate 9100.

[0097] For example, see Fig.13An operation window 4710, a door body 4720 and a door body driving member 4730 may be provided on the box body 4700. The spotting plate 9100 may be placed on the working surface 4310 through the operation window 4710. The door body driving member 4730 may be connected to the door body 4720. The door body 4720 may be moved between a first position of covering the operation window 4710 and a second position of opening the operation window 4710 through the door body driving member 4730. When the heating color developing device 4100 is idle, or when the heating color developing device 4100 is heating and coloring the spotting plate 9100 placed on the working surface 4310, the door body driving member 4730 can control the door body 4720 to cover the operation window 4710, that is, at this time, the door body driving member 4730 can make the door body 4720 located at the first position; when the spotting plate 9100 needs to be placed on the working surface 4310, or when the spotting plate 9100 placed on the working surface 4310 needs to be taken out, the door body driving member 4730 can control the door body 4720 to open the operation window 4710, that is, at this time, the door body driving member 4730 can make the door body 4720 located at the second position. Such a heating color developing device 4100 can have a higher level of automation.

[0098] Exemplarily, the color developing device 4000 may further include an ultraviolet color developing device 4900. After the infiltration is completed, the spotting plate 9100 may be moved to the ultraviolet color developing device 4900, which may emit ultraviolet rays to develop the color of the spotting plate 9100.

[0099] Exemplarily, the spotting device may further include a spotting plate loading device 7000. The spotting plate 9100 may be stored on the spotting plate loading device 7000. When spotting is required, the spotting plate loading device 7000 may move the spotting plate 9100 to the spotting plate loading position. Then, the spotting plate 9100 may be moved to the spotting device 1000. It should be noted that the spotting plate 9100 may be moved between the spotting plate loading device 7000, the spotting device 1000, the display cylinder device 2000, the immersion device 3000, and the color development device 4000 by a handling device such as a robotic arm, or may be moved manually.

[0100] The sample plate loading device 7000 can adopt any suitable structure. Exemplarily, the sample plate loading device 7000 can adopt a turntable structure. Specifically, the sample plate loading device 7000 can rotate the sample plate 9100 to move the sample plate 9100 to the sample plate loading position. In this way, the sample plate loading device 7000 has a compact structure, thereby saving space.

[0101] Exemplarily, the spotting device may further include a spotting liquid loading device 8000. The spotting liquid may be stored on the spotting liquid loading device 8000. When spotting is required, the spotting liquid loading device 8000 may move the spotting bottle containing the spotting liquid to the spotting liquid loading position. The spotting needle 1310 of the spotting device 1000 may absorb the spotting liquid located at the spotting liquid loading position to perform spotting.

[0102] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by directional words such as "front", "back", "up", "down", "left", "right", "lateral", "vertical", "vertical", "horizontal", "top", "bottom", etc. is usually based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present invention; the directional words "inside" and "outside" refer to the inside and outside relative to the contour of each component itself.

[0103] For ease of description, regional relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the regional positional relationship between one or more components or features shown in the figure and other components or features. It should be understood that regional relative terms include not only the orientation of the components as described in the figure, but also different orientations in use or operation. For example, if the components in the accompanying drawings are inverted as a whole, the components "above other components or features" or "above other components or features" will include the situation where the components are "below other components or structures" or "below other components or structures". Therefore, the exemplary term "above" may include both "above" and "below". In addition, these components or features may also be positioned at other different angles (e.g., rotated 90 degrees or other angles), and this article is intended to include all of these situations.

[0104] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, parts, components and / or combinations thereof.

[0105] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchanged where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein.

[0106] The present invention has been described by the above embodiments, but it should be understood that the above embodiments are only for the purpose of example and description, and are not intended to limit the present invention to the scope of the described embodiments. In addition, it can be understood by those skilled in the art that the present invention is not limited to the above embodiments, and more variations and modifications can be made according to the teachings of the present invention, and these variations and modifications all fall within the scope of the protection claimed by the present invention. The protection scope of the present invention is defined by the attached claims and their equivalents.

Claims

1. A spotting device, characterized in that: include: A spotting device, the spotting device is used to spot the spotting liquid onto the spotting plate; An exhibition cylinder device, the exhibition cylinder device comprises an exhibition cylinder and a placement rack, the exhibition cylinder comprises a cavity and an opening is formed at one end of the cavity, the cavity is connected to a plurality of liquid inlet pipes for injecting a developing agent into the cavity according to a predetermined ratio, and a liquid discharge pipe for discharging the developing agent in the cavity, the spotting plate after spotting is arranged in the cavity through the placement rack, so that the developing agent in the cavity is spread on the spotting plate; An infiltration device, the infiltration device is used to infiltrate the developed spotting plate; as well as A color developing device is used to develop the color of the spotting plate after infiltration.

2. The spotting device according to claim 1, characterized in that: The placement rack includes a support portion arranged on the edge of the opening and a positioning portion connected to the support portion and located in the display cylinder. The spotting plate is positioned in the cavity through the positioning portion. An insertion port is formed on the support portion, and the insertion port is connected to the opening.

3. The spotting device according to claim 2, characterized in that: The positioning portion is formed by extending from the opening into the cavity through the edge of the insertion port, and the bottom of the positioning portion is suspended.

4. The spotting device as claimed in claim 3, characterized in that: The positioning portion limits the height direction of the spot plate to be parallel to the developing agent in the cavity; or The spotting plate has a first end close to the opening and a second end away from the opening, and the positioning portion defines that the spotting plate gradually moves away from the positioning portion from the first end to the second end.

5. The spotting device according to claim 3, characterized in that: The positioning portion is provided with positioning grooves with opening directions opposite to each other and both facing the center of the cavity. The spotting plate inserted into the cavity through the insertion opening extends into the positioning groove and is positioned through the positioning groove.

6. The spotting device according to claim 1, characterized in that: The cavity is provided with a blowing component for blowing air to the spotting plate located in the cavity.

7. The spotting device according to claim 1, characterized in that: The display cylinder device includes a plurality of display cylinder groups, each of which includes two display cylinders. The two display cylinders in each display cylinder group are connected by a display cylinder connecting piece, and the display cylinder connecting piece fixes the relative position between the two display cylinders. The two display cylinders in each display cylinder group are each provided with a blowing piece for blowing air to the spotting plate located in the cavity. A baffle is provided on the display cylinder connecting piece, and the baffle is located between the two display cylinders and separates the two display cylinders, and the top of the baffle is not lower than the opening.

8. The spotting device according to claim 1, characterized in that: The spotting device comprises a spotting frame, a driving component and a spotting component, wherein the main body of the driving component is arranged on the spotting frame, and the spotting component comprises a spotting needle connected to the driving component and a capping component having a penetration hole, wherein the spotting needle can be raised and lowered along the penetration hole, and the driving component is configured to: after driving the capping component to press the bottle cap of the sample bottle, drive the spotting needle to pass through the penetration hole and extend into the sample bottle to absorb the spotting liquid in the sample bottle, after driving the spotting needle that has completed the liquid absorption to pass through the penetration hole and detach from the sample bottle, drive the capping component to detach from the bottle cap, and then drive the spotting needle to spot the spotting liquid onto the spotting plate.

9. The spotting device according to claim 8, characterized in that: The capping member includes a capping plate and an expansion boss protruding downward from the capping plate, the through hole passes through the capping plate and the expansion boss, the driving assembly is used to drive the capping plate to press and disengage from the bottle cap, and the expansion boss is used to expand the sealing layer on the bottle cap to separate the sealing layer from the spotting needle.

10. The spotting device according to claim 9, characterized in that: The spotting device also includes an elastic component, which includes a pressure rod and an elastic member. The upper end of the elastic member is connected to the driving end of the driving component and the lower end is connected to the pressure rod. The driving component is used to drive the pressure rod to press and disengage from the bottle cap. When the expansion boss expands the sealing layer, the pressure rod presses the bottle cap to compress the elastic member and make the elastic member have elastic potential energy to drive the pressure rod to protrude downward from the expansion boss.

11. The spotting device according to claim 1, characterized in that: The color developing device includes a heating color developing device, which includes a heater, a storage table and a heating image acquisition component. The storage table has a working surface on which the dot pattern plate can be placed. A cavity is formed inside the storage table. The cavity is connected to the heater through a first heating channel. The cavity extends on two opposite sides of the first direction to form a second heating channel and a third heating channel. A first air outlet is formed at one end of the second heating channel away from the cavity, and a second air outlet is formed at one end of the third heating channel away from the cavity. There is a gap between the first air outlet and the second air outlet, and both blow air toward the working surface. The heating image acquisition component collects the color development of the dot pattern plate placed on the working surface through the gap.

12. The spotting device according to claim 11, characterized in that: A connecting plate is provided on the storage table, a connecting plate opening is provided on the connecting plate, the first heating channel is connected with the cavity through the connecting plate opening, and a heat insulating member is provided on at least one side of the connecting plate in a second direction perpendicular to the first direction.

13. The spotting device according to claim 11, characterized in that: The heating color developing device includes a box body, the storage table, the second heating channel and the third heating channel are all located inside the box body, the heater is located outside the box body, the first heating channel passes through a side surface of the box body and is connected between the storage table and the heater, the box body is provided with an operation window, a door body and a door body driving component, the dot pattern plate is placed on the working surface through the operation window, the door body driving component is connected to the door body, and the door body moves between a first position covering the operation window and a second position opening the operation window through the door body driving component.