Cell factor purification instrument convenient for feeding
The cytokine purification instrument addresses the challenge of simultaneous centrifugal processing by using a driven wheel and servo motor for synchronized centrifugation and transfer, ensuring efficient cytokine separation and medium addition without spillage.
Patent Information
- Application Number
- CN202420516133.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-18
- Publication Date
- 2024-12-10
- Estimated Expiration
- 2034-03-18
AI Technical Summary
Existing cytokine purification instruments face challenges in controlling the centrifugal purification time for different types of cytokines without affecting other groups, leading to difficulties in simultaneous processing.
A cytokine purification instrument with a driven wheel, servo motor, and centrifugal assembly that allows for synchronized centrifugation and purification of different types of cytokines by varying the placement rack heights and using a gas rod for transferring centrifuged tubes, along with a protective component to prevent medium spillage.
Enables synchronized centrifugation and purification of different cytokines in separate areas, facilitating easy medium addition without tube shaking and spillage, enhancing operational efficiency.
Smart Images

Figure CN222132225U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of purification instruments, in particular to a cytokine purification instrument which is convenient for feeding. Background Art
[0002] The first step of homogenate fractionation is differential centrifugation. In a series of centrifugation processes, the centrifugal force is gradually increased and the organelles are added to a medium with a density gradient for centrifugation to separate the medium.
[0003] However, when the cytokine purification instrument simultaneously performs centrifugal purification on different types of cytokines, it is difficult to control the centrifugal purification time of another group of cytokines without affecting the centrifugation of one group of cytokines according to the different types of cytokines.
[0004] Therefore, in view of this, the existing structure and defects are studied and improved, and a cytokine purification instrument with convenient material loading is provided. Utility Model Content
[0005] The purpose of the utility model is to provide a cytokine purification instrument with convenient material feeding, so as to solve the problems raised in the above background technology.
[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a cytokine purification instrument with convenient feeding, comprising a main body and a driven wheel, a limited position channel is arranged inside the main body, and a gas rod is installed inside the limited position channel, a connecting column is connected to the output end of the gas rod, and two groups of connecting columns are arranged, a centrifugal assembly for centrifugal purification is installed on the outer surface of one group of connecting columns, and the centrifugal assembly comprises a fixed rod, a connecting plate, a servo motor and a driving shaft, a connecting plate is installed on the top of the fixed rod, and a servo motor is arranged in the middle of the connecting plate, a driving shaft is installed on the output end of the servo motor, and a placing rack is installed on the top of the driving shaft, a driving wheel is installed on the outer surface of the driving shaft, the driven wheel is meshed and arranged on one side of the driving wheel, and a connecting shaft is installed inside the driven wheel, an auxiliary frame is installed on the top of the connecting shaft, a chassis is arranged at the bottom of the connecting shaft, an auxiliary frame is arranged on one side of the main body, and a baffle is installed on the top of the auxiliary frame.
[0007] Furthermore, the baffle is engaged and connected with the auxiliary frame, and the auxiliary frame is a hollow structure.
[0008] Furthermore, two groups of the position limiting tracks are provided, and the two groups of the position limiting tracks have the same structure.
[0009] Furthermore, a protective component for shielding and protecting the main body is disposed on the top outer surface of the main body, and the protective component includes a connecting block and a rotating shaft, and the connecting block is rotatably installed with a rotating shaft inside.
[0010] Furthermore, the protection component further includes a connecting plate and a protection plate, and connecting plates are installed on both sides of the outer surface of the rotating shaft, and the protection plate is arranged at the end of the connecting plate.
[0011] Furthermore, the connecting plate and the protection plate form a fixed structure through screws, and the connecting plate and the rotating shaft are of an integral structure.
[0012] Furthermore, the limiting channel is in a "C"-shaped structure, and the inside of the limiting channel is slidably connected with the connecting column.
[0013] Furthermore, the connecting column and the fixing rod are of an integral structure, and the connecting column is in a cylindrical structure.
[0014] The utility model provides a cytokine purification instrument convenient for feeding, which has the following beneficial effects:
[0015] 1. Through the design of the centrifugation component, the utility model can centrifuge and purify the cells in the test tube placed in the placement rack in a limited way. By rotating the driving shaft, the driven wheel meshed with it can be driven to rotate synchronously, so as to drive the auxiliary frame and the connecting shaft to rotate. The different heights of the auxiliary frame and the placement rack are convenient for separating and placing test tubes for centrifugation and purification of different types in different areas and centrifuging them synchronously.
[0016] 2. When the centrifugation of the test tube in the auxiliary frame is completed, the utility model can use the design of the air rod to move the connecting column and the chassis, so that the centrifuged test tube can be transferred to the inside of the auxiliary frame, which is convenient for the operator to open the baffle and add medium into the test tube halfway to assist in purification, and avoid the spillage caused by the shaking of the test tube held by the user when adding the medium. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 is a schematic diagram of the overall structure of a cytokine purification instrument convenient for feeding according to the utility model;
[0018] Figure 2 is a schematic side view structure diagram of a cytokine purification instrument convenient for feeding according to the utility model;
[0019] Figure 3 is a schematic diagram of the connection structure of the centrifugation component of a cytokine purification instrument convenient for feeding according to the utility model;
[0020] Figure 4 is a schematic top view structure diagram of the limiting channel of a cytokine purification instrument convenient for feeding according to the utility model.
[0021] In the figure: 1. main body; 2. protective component; 201. connecting block; 202. rotating shaft; 203. connecting plate; 204. protective plate; 3. limiting track; 4. auxiliary frame; 5. baffle; 6. centrifugal component; 601. fixing rod; 602. connecting plate; 603. servo motor; 604. driving shaft; 7. placing rack; 8. driving wheel; 9. auxiliary rack; 10. connecting shaft; 11. driven wheel; 12. chassis; 13. gas rod; 14. connecting column. DETAILED DESCRIPTION
[0022] The following is a further detailed description of the implementation of the present utility model in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present utility model, but cannot be used to limit the scope of the present utility model.
[0023] like Figure 1 , Figure 2 and Figure 4As shown in the figure, a cytokine purification instrument that facilitates feeding includes a main body 1, a protection component 2, a connection block 201, a rotating shaft 202, a connection plate 203, a protection plate 204, a limiting channel 3, an auxiliary frame 4, a baffle 5, a centrifugation component 6, a fixing rod 601, a connection disk 602, a servo motor 603, a driving shaft 604, a placement rack 7, a driving wheel 8, an auxiliary frame 9, a connection shaft 10, a driven wheel 11, a chassis 12, a pneumatic rod 13, and a connection column 14. A limiting channel 3 is arranged inside the main body 1, and a pneumatic rod 13 is installed inside the limiting channel 3. The limiting channel 3 is in a "C" - shaped structure, and the inside of the limiting channel 3 is slidably connected to the connection column 14. A protection component 2 for shielding and protecting the main body 1 is arranged on the outer surface of the top of the main body 1. The protection component 2 includes a connection block 201 and a rotating shaft 202. The rotating shaft 202 is rotatably installed inside the connection block 201. The protection component 2 further includes a connection plate 203 and a protection plate 204. Both sides of the outer surface of the rotating shaft 202 are provided with connection plates 203. The end of the connection plate 203 is provided with a protection plate 204. The connection plate 203 and the protection plate 204 form a fixed structure through screws, and the connection plate 203 and the rotating shaft 202 are of an integrated structure. Through the design of the rotational connection of the connection block 201 and the rotating shaft 202, and the connection of the rotating shaft 202 with the connection plate 203, the protection plate 204 connected to the connection plate 203 can rotate by using the design of the rotational connection of the connection block 201 and the rotating shaft 202, so that the protection plate 204 can be snap - limited on the top of the main body 1, thereby being able to protect the centrifugal purification component from the top of the main body 1. There are two groups of limiting channels 3, and the structures of the two groups of limiting channels 3 are the same. The output end of the pneumatic rod 13 is connected to the connection column 14, and there are two groups of connection columns 14. The connection column 14 and the fixing rod 601 are of an integrated structure, and the connection column 14 is in a cylindrical structure. A centrifugation component 6 for performing centrifugal purification is installed on the outer surface of one group of connection columns 14. The centrifugation component 6 includes a fixing rod 601, a connection disk 602, a servo motor 603, and a driving shaft 604. The top of the fixing rod 601 is installed with a connection disk 602, and a servo motor 603 is arranged in the middle of the connection disk 602. The output end of the servo motor 603 is installed with a driving shaft 604, and the top of the driving shaft 604 is installed with a placement rack 7. The user can place the test tube to be centrifugally purified in the area of the placement rack 7, and then can rotate the placement rack 7 by using the interaction between the servo motor 603 and the driving shaft 604, so as to centrifugally purify the cells in the test tube placed in the placement rack 7 in a limited way.
[0024] As Figure 3As shown, the outer surface of the driving shaft 604 is installed with a driving wheel 8, and the driven wheel 11 is meshed and arranged on one side of the driving wheel 8, and the interior of the driven wheel 11 is installed with a connecting shaft 10, and the top of the connecting shaft 10 is installed with an auxiliary frame 9, and the rotation of the driving shaft 604 can synchronously drive the driven wheel 11 meshed with it to rotate, thereby driving the auxiliary frame 9 and the connecting shaft 10 to rotate, and the auxiliary frame 9 and the placement frame 7 are at different heights to facilitate the separation of different types of test tubes that need to be centrifuged and purified, and to place them in different areas and centrifuge them synchronously, and the bottom of the connecting shaft 10 is A chassis 12 is provided on the main body 1, an auxiliary frame 4 is provided on one side of the main body 1, and a baffle 5 is installed on the top of the auxiliary frame 4, the baffle 5 is snap-connected with the auxiliary frame 4, and the auxiliary frame 4 is a hollow structure. After the centrifugation of the test tube in the auxiliary frame 9 is completed, the connection column 14 and the chassis 12 can be moved by utilizing the design of the gas rod 13, so that the test tube after centrifugation can be transferred to the inside of the auxiliary frame 4, which is convenient for the operator to open the baffle 5 to add medium to the test tube for auxiliary purification, thereby preventing the user from shaking the test tube in hand and causing the medium to spill when added.
[0025] In summary, the cytokine purification instrument with convenient feeding is first based on Figure 1-Figure 4 According to the structure shown in the figure, the user can place the test tube to be centrifuged and purified in the area of the placement rack 7, and then use the interaction between the servo motor 603 and the drive shaft 604 to rotate the placement rack 7, so that the cells in the test tube limitedly placed in the placement rack 7 can be centrifuged and purified, and then through the design of the connection block 201 and the rotating shaft 202 being rotatably connected, the rotating shaft 202 is connected to the connecting plate 203, so that the protective plate 204 connected to the connecting plate 203 can be rotated by using the design of the connection block 201 and the rotating shaft 202 being rotatably connected, so that the protective plate 204 can be engaged and limited at the top of the main body 1, so that the centrifuge can be purified from the top of the main body 1. The purification component is protected, wherein the rotation of the drive shaft 604 can synchronously drive the driven wheel 11 meshing therewith to rotate, thereby driving the auxiliary frame 9 and the connecting shaft 10 to rotate, and the auxiliary frame 9 and the placement frame 7 have different heights, which is convenient for separating and placing different types of test tubes that need to be centrifuged and purified in different areas and for synchronous centrifugation. After the centrifugation of the test tubes in the auxiliary frame 9 is completed, the design of the gas rod 13 can be used to mobilize the connection column 14 and the chassis 12 to move the position, so that the test tubes after centrifugation can be transferred to the interior of the auxiliary frame 4, which is convenient for the operator to open the baffle 5 to add medium to the test tube for auxiliary purification, and avoid shaking of the test tube held by the user, which may cause spillage when adding the medium.
[0026] The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.
Claims
1. A cytokine purification instrument facilitating feeding, comprising a main body (1) and a driven wheel (11). Characterized in that: A limiting channel (3) is arranged inside the main body (1), and an air rod (13) is installed inside the limiting channel (3). The output end of the air rod (13) is connected to a connecting column (14), and there are two groups of connecting columns (14). A centrifugal purification component (6) for centrifugal purification is installed on the outer surface of one group of connecting columns (14). The centrifugal purification component (6) includes a fixing rod (601), an adapter plate (602), a servo motor (603), and a driving shaft (604). The top of the fixing rod (601) is installed with an adapter plate (602), and a servo motor (603) is arranged in the middle of the adapter plate (602). The output end of the servo motor (603) is installed with a driving shaft (604), and a placement rack (7) is installed at the top of the driving shaft (604). A driving wheel (8) is installed on the outer surface of the driving shaft (604). The driven wheel (11) is meshed with one side of the driving wheel (8), and a connecting shaft (10) is installed inside the driven wheel (11). The top of the connecting shaft (10) is installed with an auxiliary frame (9), and the bottom of the connecting shaft (10) is provided with a chassis (12). An auxiliary frame (4) is arranged on one side of the main body (1), and a baffle (5) is installed at the top of the auxiliary frame (4).
2. The cytokine purification instrument facilitating feeding according to claim 1, Characterized in that, The baffle (5) is snap - connected to the auxiliary frame (4), and the auxiliary frame (4) is of a hollow structure.
3. The cytokine purification instrument facilitating feeding according to claim 1, Characterized in that, There are two groups of limiting channels (3), and the two groups of limiting channels (3) have the same structure.
4. The cytokine purification instrument facilitating feeding according to claim 1, Characterized in that, A protection component (2) for shielding and protecting the main body (1) is arranged on the outer surface of the top of the main body (1). The protection component (2) includes a connection block (201) and a rotating shaft (202). The rotating shaft (202) is rotatably installed inside the connection block (201).
5. The cytokine purification instrument facilitating feeding according to claim 4, Characterized in that, The protection component (2) further includes a connection plate (203) and a protection plate (204). Connection plates (203) are installed on both sides of the outer surface of the rotating shaft (202), and the end of the connection plate (203) is provided with a protection plate (204).
6. The cytokine purification instrument facilitating feeding according to claim 5, Characterized in that, The connection plate (203) and the protection plate (204) form a fixed structure through screws, and the connection plate (203) and the rotating shaft (202) are of an integrated structure.
7. The cytokine purification instrument facilitating feeding according to claim 1, Characterized in that, The limiting channel (3) is in a "C" - shaped structure, and the inside of the limiting channel (3) is slidably connected to the connecting column (14).
8. A cytokine purification instrument with convenient feeding according to claim 1, It is characterized in that The connecting column (14) and the fixing rod (601) are an integrated structure, and the connecting column (14) is a cylindrical structure.
