Screening device for insulin production

Abstract

The utility model discloses a screening device for insulin production, which belongs to the technical field of insulin production, and comprises a fixed column, the outer side wall of the fixed column is slidably connected with a second moving ring, the outer side wall of the second moving ring is fixedly connected with a telescopic rod, the telescopic end of the telescopic rod is fixedly connected with an adjusting ring, and the inner side wall of the adjusting ring is provided with a feed hopper. A filtering hopper is inserted into the inner side wall of the feeding hopper, a plurality of filtering holes are formed in the bottom of the filtering hopper, the inner side wall of the adjusting ring is fixedly connected with a limiting ring, and a limiting groove is formed in the inner side wall of the feeding hopper. According to the screening device for insulin production, an adjusting ring is adjusted through a telescopic rod, so that the adjusting ring can drive a feeding hopper to move, a filtering hopper is installed in the feeding hopper, and a plurality of filtering holes are formed in the bottom of the filtering hopper; bacterial sludge particles in the insulin production raw materials can be filtered through the filtering holes formed in the bottom of the filtering hopper, and the influence of the bacterial sludge particles on insulin production is avoided.

Description

Technical Field

[0001] The utility model belongs to the technical field of insulin production, and specifically relates to a screening device for insulin production. Background Art

[0002] Insulin is an important biological drug. It is a protein hormone secreted by the pancreatic β cells of the human body. It is mainly involved in regulating sugar metabolism. In the treatment of diabetes, insulin is an indispensable drug.

[0003] When insulin is produced, a chromatography column is needed to separate insulin. However, the raw materials for insulin production contain bacterial sludge particles. When the raw materials enter the chromatography column for separation, the bacterial sludge particles will block the discharge port at the bottom of the chromatography column, thereby affecting the normal use of the chromatography column and further affecting the production of insulin.

[0004] In order to solve the above problems, the present application proposes a screening device for insulin production. Utility Model Content

[0005] In view of the problems in the related technology, the utility model proposes a screening device for insulin production to overcome the above technical problems existing in the existing related technology.

[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0007] A screening device for insulin production comprises a fixed column, the outer side wall of the fixed column is slidably connected to a second movable ring, the outer side wall of the second movable ring is fixedly connected to a telescopic rod, the telescopic end of the telescopic rod is fixedly connected to an adjusting ring, the inner side wall of the adjusting ring is provided with a feed hopper, the inner side wall of the feed hopper is inserted with a filter hopper, and the bottom of the filter hopper is provided with a plurality of filter holes.

[0008] Preferably, the inner side wall of the adjustment ring is fixedly connected to a limiting ring, and the inner side wall of the feed hopper is provided with a limiting groove.

[0009] By providing the limiting ring and the limiting groove, the limiting groove opened through the outer wall of the feed hopper is adapted to the limiting ring installed inside the adjusting ring, so that the feed hopper can be effectively limited inside the adjusting ring.

[0010] Preferably, the outer side wall of the second movable ring is fixedly connected with a fixing block, the inner side wall of the fixing block is threadedly inserted with a threaded rod, and the outer side wall of the fixing column is provided with a fixing groove.

[0011] By setting a fixing block, a threaded rod and a fixing groove, the threaded rod is inserted into the fixing block and fixed in the fixing groove, so that the second movable ring can be fixed to the outer wall of the fixing column to prevent the second movable ring from sliding.

[0012] Preferably, the outer side wall of the fixed column is slidably connected to a first movable ring, the outer side wall of the first movable ring is fixedly connected to a fixed rod, and one end of the fixed rod away from the first movable ring is fixedly connected to a support ring.

[0013] By providing the first movable ring, the fixed rod and the support ring, the first movable ring can slide up and down on the outer side wall of the fixed column, so that the support ring can move up and down under the connection of the fixed rod.

[0014] Preferably, the inner side wall of the support ring is fitted with a chromatography column, and the support ring is funnel-shaped and fits with the outer side wall of the lower end of the chromatography column.

[0015] By setting the chromatography column, it is achieved that the chromatography column is installed inside the support ring, and the chromatography column can be effectively supported by the funnel-shaped support ring to prevent the chromatography column from shaking during operation.

[0016] Preferably, the bottom of the fixing column is fixedly connected to a base, and a collection frame is attached to the top center of the base.

[0017] By setting up the base and the collecting frame, it is achieved that by fixing the fixed column on the top of the base, the chromatography column and the feed hopper can be supported by the fixed column, so that the chromatography column and the feed hopper are located above the collecting frame, and insulin can be effectively collected.

[0018] To sum up, the technical effects and advantages of the utility model are as follows: the screening device for insulin production adjusts the adjusting ring through the telescopic rod, so that the adjusting ring can drive the feed hopper to move, and a filter hopper is installed inside the feed hopper, and a plurality of filter holes are opened at the bottom of the filter hopper. The bacterial mud particles in the raw materials for insulin production can be filtered through the filter holes opened at the bottom of the filter hopper to avoid the influence of the bacterial mud particles on the production of insulin.

[0019] Through the fixing groove opened on the outer wall of the fixed column, the threaded rod passes through the fixing block and is inserted into the interior of the fixing groove for position fixing, so that the second movable ring can be fixed on the outer wall of the fixed column, thereby the height of the second movable ring can be adjusted, so that the first movable ring and the second movable ring can be freely adjusted in height, and the collection frame is located at the bottom of the chromatography column, so that the produced insulin can be effectively collected through the collection frame. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0021] Figure 2 This is a schematic diagram of the chromatography column of the utility model and its related structures;

[0022] Figure 3 This is a schematic diagram of the filter bucket and its related structures of the utility model;

[0023] Figure 4 This is a schematic diagram of the fixing groove and its related structures of the utility model.

[0024] In the figure: 1. fixed column; 2. first movable ring; 3. fixed rod; 4. support ring; 5. chromatography column; 6. second movable ring; 7. telescopic rod; 8. adjustment ring; 9. feed hopper; 10. limiting ring; 11. limiting groove; 12. filter hopper; 13. filter hole; 14. fixed block; 15. threaded rod; 16. fixed groove; 17. base; 18. collection frame. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0026] Reference Figure 1-3 A screening device for insulin production comprises a fixed column 1, the outer wall of the fixed column 1 is slidably connected with a second movable ring 6, the outer wall of the second movable ring 6 is fixedly connected with a telescopic rod 7, the telescopic end of the telescopic rod 7 is fixedly connected with an adjusting ring 8, the inner wall of the adjusting ring 8 is provided with a feed hopper 9, the inner wall of the feed hopper 9 is inserted with a filter hopper 12, and a plurality of filter holes 13 are provided at the bottom of the filter hopper 12. By installing the feed hopper 9 inside the adjusting ring 8 and adjusting the distance between the adjusting ring 8 and the fixed column 1 by the telescopic rod 7, the position of the feed hopper 9 can be adjusted, the height of the second movable ring 6 can be adjusted by sliding the second movable ring 6 on the fixed column 1, the insulin raw material is filtered by the filter hopper 12 installed inside the feed hopper 9, the bacterial mud particles contained in the insulin are filtered through the filter holes 13, the bacterial mud particles in the insulin are collected inside the filter hopper 12, and the bacterial mud particles can be driven to be removed by the filter hopper 12.

[0027] Reference Figure 2-4 The inner wall of the adjusting ring 8 is fixedly connected to the limiting ring 10, and the inner wall of the feed hopper 9 is provided with a limiting groove 11. The limiting groove 11 provided on the outer wall of the feed hopper 9 is adapted to the limiting ring 10 installed inside the adjusting ring 8, so that the feed hopper 9 can be effectively installed inside the adjusting ring 8 to prevent the feed hopper 9 from shaking during use.

[0028] Reference Figure 4The outer wall of the second movable ring 6 is fixedly connected with a fixed block 14, and the inner wall of the fixed block 14 is threadedly inserted with a threaded rod 15. The outer wall of the fixed column 1 is provided with a fixing groove 16. The fixed block 14 is installed on the outer wall of the second movable ring 6, and the threaded rod 15 is inserted into the interior of the fixed block 14 so that the threaded rod 15 can pass through the fixed block 14 and enter the interior of the fixing groove 16 for limiting, so that the second movable ring 6 can be fixed on the outer wall of the fixed column 1.

[0029] Reference Figure 1-2 The outer wall of the fixed column 1 is slidably connected with the first movable ring 2, the outer wall of the first movable ring 2 is fixedly connected with the fixing rod 3, and the end of the fixing rod 3 away from the first movable ring 2 is fixedly connected with the supporting ring 4. The first movable ring 2 moves up and down on the outer wall of the fixed column 1, so that the fixing rod 3 fixes the first movable ring 2 and the supporting ring 4, so that the supporting ring 4 moves synchronously with the first movable ring 2 and the supporting ring 4 moves up and down.

[0030] Reference Figure 1-2 The inner wall of the support ring 4 is fitted with a chromatography column 5, and the support ring 4 is funnel-shaped and fits with the outer wall of the lower end of the chromatography column 5. By installing the chromatography column 5 inside the support ring 4, the lower end of the chromatography column 5 is limited by the support ring 4 to prevent the chromatography column 5 from falling off after installation, so that the support ring 4 can effectively drive the chromatography column 5 to move up and down, and the chromatography column 5 is limited and fixed under the action of the first moving ring 2.

[0031] Reference Figure 1-2 The bottom of the fixed column 1 is fixedly connected to a base 17, and a collecting frame 18 is attached to the top center of the base 17. The fixed column 1 is installed and fixed by the base 17 to prevent the fixed column 1 from collapsing. By installing the collecting frame 18 at the top center of the base 17, the chromatography column 5 discharges the filtered insulin into the collecting frame 18 issued downward.

[0032] Working principle: by installing the chromatography column 5 inside the support ring 4, and driving the support ring 4 to move up and down through the first movable ring 2, the support ring 4 can drive the chromatography column 5 to move up and down, so that the chromatography column 5 can be effectively installed above the collecting frame 18, and the chromatography column 5 is inserted into the second movable ring 6, so that the threaded rod 15 can be inserted into the fixing groove 16 to fix the second movable ring 6, so that the second movable ring 6 can be installed at any position on the outer wall of the fixed column 1, and the distance of the adjusting ring 8 is adjusted by the telescopic rod 7, so that the adjusting ring 8 drives the feed hopper 9 to be effectively located above the chromatography column 5, so that the feed hopper 9 allows the filtered insulin production raw materials to enter the interior of the chromatography column 5, avoiding filtering of the bacterial mud particles contained in the insulin production raw materials, and collecting and processing the bacterial mud particles in the insulin production raw materials through the filtering bucket 12, avoiding clogging of the discharge port at the bottom of the chromatography column 5 by the bacterial mud particles, and the produced insulin can be collected through the collecting frame 18.

[0033] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A screening device for insulin production, comprising a fixed column (1), characterized in that: The outer side wall of the fixed column (1) is slidably connected to a second movable ring (6), the outer side wall of the second movable ring (6) is fixedly connected to a telescopic rod (7), the telescopic end of the telescopic rod (7) is fixedly connected to an adjustment ring (8), the inner side wall of the adjustment ring (8) is provided with a feed hopper (9), the inner side wall of the feed hopper (9) is inserted with a filter hopper (12), and the bottom of the filter hopper (12) is provided with a plurality of filter holes (13).

2. A screening device for insulin production according to claim 1, characterized in that: The inner side wall of the adjustment ring (8) is fixedly connected to a limiting ring (10), and the inner side wall of the feed hopper (9) is provided with a limiting groove (11).

3. A screening device for insulin production according to claim 1, characterized in that: The outer side wall of the second movable ring (6) is fixedly connected to a fixing block (14), the inner side wall of the fixing block (14) is threadedly inserted with a threaded rod (15), and the outer side wall of the fixing column (1) is provided with a fixing groove (16).

4. The screening device for insulin production according to claim 1, characterized in that: The outer wall of the fixed column (1) is slidably connected to a first movable ring (2), the outer wall of the first movable ring (2) is fixedly connected to a fixed rod (3), and one end of the fixed rod (3) away from the first movable ring (2) is fixedly connected to a support ring (4).

5. A screening device for insulin production according to claim 4, characterized in that: The inner side wall of the support ring (4) is fitted with a chromatography column (5), and the support ring (4) is funnel-shaped and fits with the outer side wall of the lower end of the chromatography column (5).

6. The screening device for insulin production according to claim 1, characterized in that: The bottom of the fixed column (1) is fixedly connected to a base (17), and a collection frame (18) is attached to the center of the top of the base (17).

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