The invention discloses a printing device for packaging box production. The device comprises a fixed seat, fixing rods are fixed to the two sides of the outer wall of the top of the fixing base respectively, a top plate is fixed to the outer walls of the tops of the two fixing rods correspondingly, an electric telescopic rod is fixed to the outer wall of the bottom of the top plate, a fixing plateis fixed to the outer wall of the bottom of the electric telescopic rod, an electric sliding rail is fixed to the outer wall of the bottom of the fixing plate, a sliding block is slidably connected to the inner wall of the electric sliding rail, a fixing shaft is fixed to the outer wall of the bottom of the sliding block, a fixing frame is fixed to the outer wall of the bottom of the fixing shaft, and a template is arranged on the inner wall of the fixing frame. According to the invention, influence of blurred printed handwriting on packaging box production can be prevented, the bottom of thetemplate can be prevented from being abraded to influence printing of the packaging box, deviation of printing of the device on the packaging box can be prevented, and deviation of printing of the packaging box caused by movement between the packaging box and the clamping due to vibration can be prevented.