The invention relates to a plastic bottle packing system and a packing process thereof. The plastic bottle packing system comprises a conveying belt, bottom board putting machines, a case unpacking machine, case packing stations, a grabbing station, an automatic weighing machine, certificate of approval putting machines, specification putting machines, top board putting machines, an automatic case sealing machine and an ink-jet printer. Packing is carried out through processes of case unpacking, conveying and case packing, weighing and rejecting, certificate of approval and specification putting, top board putting, case sealing, electronic supervision code spraying, and removal of unqualified electronic supervision code. The plastic bottle packing system and the packing process have the advantages that automatic packing effect is realized, labor cost is lowered, wrong packing is avoided, working efficiency in packing is improved, production efficiency in packing is improved, economic benefit of enterprises is increased, 100ml plastic bottles, 200ml plastic bottles, 500ml plastic bottles and upright soft bags can be packed, the problem that one original production line can only be used for packing plastic bottles of one specification is solved, using effect is good, and popularization is facilitated.