The invention discloses a release packer capable of well-flushing, which comprises an upper joint, a piston, a hydraulic cylinder, a separating joint, an ejector sleeve, a packing valve ball, a packing valve seat, a packing shear pin, a lock ring, a junk sub, a connected pipe, an inner pipe, an unset shear pin, an upper rubber cylinder joint, a rubber cylinder shaft, a rubber cylinder, a lower rubber cylinder joint, an upper cone, a slip sleeve, a slip, a lower cone, and a stop joint; wherein the lower cone is provided with a communicated hole and internally provided with a sliding sleeve; the sliding sleeve is positioned above the communicated hole and fixed on the lower cone; the upper part of the sliding sleeve is provided with an upper seal ring, and the lower part of the sliding sleeve is provided with a lower seal ring; a pin is positioned between the upper seal ring and the lower seal ring; a cut-off valve ball is located in the upper port of the sliding sleeve; and the diameter of the cut-off valve ball is smaller than the inner diameter of the packing valve seat. Before packing, the reverse well flushing can be carried out on an oil pipe on the packer so as to wash way sundries in the oil pipe and ensure that a packing pressure is transferred to the piston, the packer can be reliably packed and the well flushing can successfully realize oil production by layer, thereby the invention has obvious economic benefit.