SERS (Surface Enhanced Raman Scattering) substrate objective table applied to portable Raman spectrometer detection

Abstract

The utility model discloses an SERS (Surface Enhanced Raman Scattering) substrate objective table applied to portable Raman spectrometer detection, which comprises a base, a support rod, a Raman probe support, an objective table slide rail, a pull-out type objective box and an inverted trapezoidal linear guide rail slide block, the pull-out type objective box comprises an objective box and a circular objective disc, the circular objective disc is clamped in a square groove of the objective box, and the objective table slide rail slide block is connected with the support rod. The round carrying disc is composed of a round groove disc and V-shaped elastic pieces, the V-shaped elastic pieces are connected by welding second elastic pieces to first elastic pieces, and the four V-shaped elastic pieces are welded to the edge of the round groove disc according to the same interval angle. The drawing type object carrying box can fix a plurality of samples to be tested at the same time and is easy to replace; the SERS substrate objective table is suitable for a Raman probe with the diameter smaller than 1.5 cm, and optimal Raman signal collection can be achieved by adjusting the positions of the pull-out type object carrying box and the Raman probe at the same time.

Description

Technical Field

[0001] The utility model relates to an object platform, in particular to an object platform applied in portable Raman spectrum detection, belonging to the field of spectrum detection devices. Background Art

[0002] Surface enhanced Raman scattering (SERS) is a highly sensitive spectroscopy technology that can increase the Raman signal of a molecule by several orders of magnitude. It has the advantages of extremely high sensitivity and specificity, rapid detection, the ability to provide molecular structure information, and the ability to detect and analyze biological molecules at the single molecule level. It is used in many fields such as biomedicine and chemical molecule detection, chemical industry, disease diagnosis, environmental monitoring, explosive detection, trace material analysis, agricultural food safety, etc. In SERS detection applications, the substrate with surface enhanced Raman scattering effect plays a decisive role in the SERS signal. The current SERS substrates include nano-precious metals, nano-precious metal composites and other substrates. These substrates are mainly formed by depositing nano-precious metals, nano-precious metal composites and other materials on silicon substrates or glass substrates using physical or chemical methods.

[0003] At present, in the Raman detection application based on SERS, the detection instruments used mainly include desktop laser confocal Raman spectrometer and portable Raman spectrometer. Desktop laser confocal Raman spectrometer has the advantages of high sensitivity, high spatial resolution, low sample concentration, and microscopic image measurement. However, its structure is complex and sophisticated, expensive, high maintenance cost, and high requirements for the experimental environment. It is generally used for high-precision Raman spectrum measurement. Portable Raman spectrometer has the advantages of simple structure, easy to carry, and convenient operation. It is widely used for rapid detection of Raman spectra of samples. When using a portable Raman spectrometer for SERS spectrum acquisition, a handheld Raman probe or a Raman probe bracket is often used for fixing. For example, the utility model patent with patent application number 201721323235.X and patent name Portable Raman spectroscopy detection device based on circular microfluidic disc proposes a portable Raman spectrometer Raman probe fixing scheme. However, for the detected SERS substrate, there are currently problems such as unfixed and easy to move or slip, and uncertain position leading to poor data acquisition repetition. Summary of the invention

[0004] In view of the problems existing in the prior art, the purpose of the present invention is to provide a SERS substrate stage for use in portable Raman spectrometer detection. The present invention has the advantages of easy fixation of detection samples, movable detection sample carrier box, and easy replacement of the circular carrier plate for loading samples.

[0005] The utility model adopts the following technical scheme: a portable Raman spectrum detection device with a pull-out loading box, comprising: a base (1), a support rod (2), a Raman probe bracket (3), a loading platform slide rail (4), a pull-out loading box (5), and an inverted trapezoidal linear guide slider (6); the base (1) is a rectangular parallelepiped, and the four sides are a first long side (7), a second long side (8), a first short side (9) and a second short side (10); threaded holes (11) are respectively opened at a distance of 2 cm from the first long side (7) and 7 cm from the first short side (9), and at a distance of 2 cm from the first long side (7) and 7 cm from the second short side (10); the support rod (2) is a first support rod (12-1) and a second support rod (12-2), and the first support rod ( 12-1) and the second support rod (12-2) are both provided with a thread (14) at one end and a spherical top (13) at the other end. The threaded end (14) of the support rod (2) is screwed into the threaded hole (11) on the base (1) for fixing. The Raman probe bracket (3) is a T-shaped structure, with a support frame (17) in the vertical direction and a slider (18) in the horizontal direction. The support frame (17) is welded to the slider (18). A Raman probe fixing hole (19) is provided at the front end of the support frame (17). A fixing knob (16) is provided at the center of the left and right sides of the Raman probe fixing hole (19). The slider (18) has two through holes (20). The distance between the two through holes (20) is 3 cm. The side of the slider (18) is provided with The Raman probe bracket (3) is mounted on the support rod (2) through the two through holes (20) of the slider (18), and the height of the Raman probe bracket (3) is adjusted by the fixed adjustment knob (15) and fixed on the support rod (2); the loading platform slide rail (4) is an inverted trapezoidal slide rail, welded to the base (1), and the two ends of the loading platform slide rail (4) are equidistant from the first short side (9) and the second short side (10), and 5 cm away from the second long side (8); the bottom of the pull-out loading box (5) is provided with an inverted trapezoidal groove, and the pull-out loading box (5) comprises: a loading box (21) and a circular loading plate (22), and the loading box (21) is provided with two rows of square grooves with equal spacing, and the The circular loading plate (22) comprises a circular groove plate (23) and a V-shaped spring sheet (24). The V-shaped spring sheet (24) is composed of a first spring sheet (25) and a second spring sheet (26). The second spring sheet (26) is connected to the first spring sheet (25) by welding. There are four V-shaped spring sheets (24) welded on the edge of the circular groove plate (23) at the same interval angle. The outer diameter of the circular loading plate (22) is equal to the inner width of the square groove of the loading box (21), and can be stuck in the square groove of the loading box (21). The upper surface of the inverted trapezoidal linear guide slider (6) is provided with an inverted trapezoidal guide rail, and the lower surface is provided with an inverted trapezoidal slide groove. The inverted trapezoidal slide rail on the upper surface of the inverted trapezoidal linear guide slider (6) is perpendicular to the inverted trapezoidal slide groove on the lower surface.The inverted trapezoidal linear guide slider (6) is connected to the object loading platform slide rail (4) via an inverted trapezoidal slide groove on the lower surface; the pull-out object loading box (5) is slidably connected via an inverted trapezoidal guide rail on the upper surface of the inverted trapezoidal linear guide slider (6).

[0006] The base (1) has a length of 20 cm, a width of 15 cm and a height of 1 cm.

[0007] The first support rod (12-1) and the second support rod (12-2) of the support rod (2) have a height of 15 centimeters and a diameter of 1.5 centimeters.

[0008] The diameter of the Raman probe fixing hole at the front end of the support frame (17) of the Raman probe bracket (3) is 1.5 cm.

[0009] The upper surface of the object-carrying platform slide rail (4) is 12 cm long and 2 cm wide, and the lower surface is 12 cm long and 1.5 cm wide.

[0010] The square groove of the object carrying box (21) has a side length of 3 cm and a depth of 0.5 cm.

[0011] The grooves on the object carrying box (21) are arranged in two rows, with 7 grooves in each row.

[0012] The inner diameter of the groove of the circular groove plate (23) is 2.6 cm, and the depth of the groove is 0.5 cm.

[0013] The height of the first spring piece (25) is 0.5 cm, and the inner angle between the second spring piece (26) and the first spring piece (25) is 40 degrees.

[0014] The above technical solution has the following beneficial effects:

[0015] 1. The Raman probe fixing hole of the Raman probe holder on the SERS substrate stage can clamp the Raman probe by adjusting the fixing knob, and is suitable for Raman probes with a diameter less than 1.5 cm.

[0016] 2. The Raman probe holder on the SERS substrate stage can be moved up and down by the support rod, which facilitates the adjustment of the laser spot size focused on the silicon substrate.

[0017] 3. The circular loading plate is provided with a circular groove plate and a V-shaped spring clip, through which SERS substrates of different sizes and shapes can be fixed; in addition, the circular loading plate is separated from the pull-out loading box and is easy to replace.

[0018] 4. The connection structure of the pull-out loading box, the inverted trapezoidal linear guide slider and the loading platform slide rail enables the pull-out loading box to move forward, backward, left and right on the SERS substrate loading platform, so that when the position of the Raman probe is determined, the Raman spectrum information of multiple samples to be tested can be collected by adjusting the position of the pull-out loading box. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The utility model is further described below in conjunction with the accompanying drawings and specific implementation methods.

[0020] Figure 1 is a schematic diagram of the SERS substrate stage structure;

[0021] Figure 2 It is a schematic diagram of the structure of the threaded hole on the base;

[0022] Figure 3 It is a structural diagram of the support rod;

[0023] Figure 4 is a schematic diagram of the structure of the Raman probe bracket;

[0024] Figure 5 is a cross-sectional schematic diagram of a pull-out type carrying box;

[0025] Figure 6 It is a structural schematic diagram of a pull-out type carrying box;

[0026] Figure 7 It is a structural schematic diagram of an inverted trapezoidal linear guide slider;

[0027] Figure 8 It is a schematic diagram of the structure of a circular loading plate;

[0028] Fig. 9 It is a schematic diagram of the V-shaped shrapnel structure;

[0029] Fig.10 It is a schematic diagram of an embodiment of the utility model.

[0030] In the figure, 1 is a base, 2 is a support rod, 3 is a Raman probe bracket, 4 is a loading platform slide rail, 5 is a pull-out loading box, 6 is an inverted trapezoidal linear guide slider, 7 is a first long side, 8 is a second long side, 9 is a first short side, 10 is a second short side, 11 is a threaded hole, 12-1 is a first support rod, 12-2 is a second support rod, 13 is a spherical top, 14 is a thread, 15 is a fixed adjustment knob, 16 is a fixed knob, 17 is a support frame, 18 is a slider, 19 is a Raman probe fixing hole, 20 is a through hole, 21 is a loading box, 22 is a circular loading plate, 23 is a circular groove plate, 24 is a V-shaped spring clip, 25 is a first spring clip, 26 is a second spring clip, 27 is a SERS substrate loading platform, 28 is a Raman probe, and 29 is a portable Raman spectrometer and a laser light source. DETAILED DESCRIPTION

[0031] Figure 1-10In the invention, a SERS substrate stage for portable Raman spectrometer detection includes: a base 1, a support rod 2, a Raman probe bracket 3, a platform slide rail 4, a pull-out loading box 5, and an inverted trapezoidal linear guide slider 6. The base 1 is a rectangular parallelepiped, with a length of 20 cm, a width of 15 cm, and a height of 1 cm. The four sides are a first long side 7, a second long side 8, a first short side 9, and a second short side 10. Threaded holes are respectively provided at 2 cm from the first long side 7 and 7 cm from the first short side 9, and at 2 cm from the first long side 7 and 7 cm from the second short side 10. The support rod 2 is a first support rod 12-1 and a second support rod 12-2, the height of the first support rod 12-1 and the second support rod 12-2 is 15 cm, and the diameter is 1.5 cm. One end of the first support rod 12-1 and the second support rod 12-2 are provided with threads 14, and the other end is a spherical top 13. The threaded end 14 of the support rod 2 is screwed into the threaded hole 11 on the base 1 for fixing. The Raman probe bracket 3 is a T-shaped structure, with a support frame 17 in the vertical direction and a slider 18 in the horizontal direction. The support frame 17 is welded to the slider 18, and a Raman probe fixing hole 19 with a diameter of 1.5 cm is provided at the front end of the support frame 17. Fixed knobs 16 are respectively provided at the center positions on the left and right sides of the Raman probe fixing hole 19, and the slider 18 has two through holes 20, and the distance between the two through holes 20 is 3 cm. A fixed adjustment knob 15 is provided on the side of the slider 18; the Raman probe bracket 3 is installed on the support rod 2 through the two through holes 20 of the slider 18, and the fixed adjustment knob 15 is used to adjust the height of the Raman probe bracket 3 and fix it on the support rod 2. The loading platform slide rail 4 is an inverted trapezoidal slide rail welded on the base 1, the upper surface of the inverted trapezoidal slide rail is 12 cm long and 2 cm wide, and the lower surface is 12 cm long and 1.5 cm wide; the two ends of the loading platform slide rail 4 are equally spaced from the first short side 9 and the second short side 10, and are 5 cm apart from the second long side 8. The bottom of the pull-out loading box 5 is provided with an inverted trapezoidal groove, and the pull-out loading box 5 includes: a loading box 21 and a circular loading plate 22, and the loading box 21 is provided with two rows of equally spaced square grooves, and there are two rows of square grooves, each row has 7 grooves, and the side length is 3 cm and the depth is 0.5 cm. The circular loading plate 22 includes a circular groove plate 23 and a V-shaped spring piece 24. The inner diameter of the groove of the circular groove plate 23 is 2.6 cm, and the depth of the groove is 0.5 cm. The V-shaped spring piece 24 is composed of a first spring piece 25 and a second spring piece 26. The height of the first spring piece 25 is 0.5 cm. The second spring piece 26 is connected to the first spring piece 25 by welding, and the inner angle between the second spring piece 26 and the first spring piece 25 is 40 degrees. There are 4 V-shaped spring pieces 24 welded on the edge of the circular groove plate 23 at the same interval angle. The outer diameter of the circular loading plate 22 is equal to the inner width of the square groove of the loading box 21, and can be stuck in the square groove of the loading box 21.The upper surface of the inverted trapezoidal linear guide slider 6 is provided with an inverted trapezoidal guide rail, and the lower surface is provided with an inverted trapezoidal slide groove. The inverted trapezoidal slide rail on the upper surface of the inverted trapezoidal linear guide slider 6 is perpendicular to the direction of the inverted trapezoidal slide groove on the lower surface; the inverted trapezoidal linear guide slider 6 is connected to the loading platform slide rail 4 through the inverted trapezoidal slide groove on the lower surface; the pull-out loading box 5 is slidably connected through the inverted trapezoidal guide rail on the upper surface of the inverted trapezoidal linear guide slider 6.

[0032] A use of a SERS substrate stage for portable Raman spectrometer detection: according to Figure 1-10 The structure shown in the figure is connected, the portable Raman spectrometer and the laser light source 29 are connected to the Raman probe 28 through the laser optical fiber, the fixed knob 16 is rotated to change the clamping space size of the Raman probe fixing hole 19, so that the Raman probe 29 is firmly stuck in the Raman probe fixing hole 19, thereby fixing the Raman probe 28 on the SERS substrate stage 27; the silicon substrate loaded with the sample to be tested is respectively clamped into the circular loading plate 22 through the V-shaped spring piece 24, and then the circular loading plate 22 is clamped in the square groove of the loading box 21, and the movement of the silicon substrate loaded with the sample to be tested is realized by controlling the pull-out loading box 5 to move forward and backward on the trapezoidal linear guide slider 6 and move left and right on the loading platform slide rail 4; the Raman probe bracket 3 can be moved up and down on the support rod 2 by adjusting the fixed adjustment knob 15, and the position of the Raman probe 29 is adjusted. By adjusting the position of the sample to be tested and the Raman probe 29 on the pull-out loading box 5, when the Raman spectrum information is optimal, Raman spectrum data collection can be performed.

Claims

1. A SERS substrate stage for portable Raman spectrometer detection, comprising: A base (1), a support rod (2), a Raman probe bracket (3), a loading platform slide rail (4), a pull-out loading box (5), and an inverted trapezoidal linear guide slider (6); the base (1) is a rectangular parallelepiped, and the four sides are a first long side (7), a second long side (8), a first short side (9), and a second short side (10); threaded holes (11) are respectively opened at a distance of 2 cm from the first long side (7) and 7 cm from the first short side (9), and at a distance of 2 cm from the first long side (7) and 7 cm from the second short side (10); the support rod (2) is a first support rod (12-1) and a second support rod (12-2), and one end of the first support rod (12-1) and the second support rod (12-2) are both provided with threads (14), The other end is a spherical top (13), and the threaded end (14) of the support rod (2) is screwed into the threaded hole (11) on the base (1) for fixing; the Raman probe bracket (3) is a T-shaped structure, with a support frame (17) in the vertical direction and a slider (18) in the horizontal direction, the support frame (17) is welded to the slider (18), the front end of the support frame (17) is provided with a Raman probe fixing hole (19), the center positions of the left and right sides of the Raman probe fixing hole (19) are respectively provided with fixing knobs (16), the slider (18) is provided with two through holes (20), the distance between the two through holes (20) is 3 cm, and the side of the slider (18) is provided with a fixed adjustment knob (15); the Raman probe bracket (3 ) is installed on the support rod (2) through the two through holes (20) of the slider (18), and the height of the Raman probe bracket (3) is adjusted by a fixed adjustment knob (15) and fixed to the support rod (2); the loading platform slide rail (4) is an inverted trapezoidal slide rail, welded to the base (1), and the two ends of the loading platform slide rail (4) are equidistant from the first short side (9) and the second short side (10), and are 5 cm away from the second long side (8); the bottom of the pull-out loading box (5) is provided with an inverted trapezoidal groove, characterized in that the pull-out loading box (5) comprises: a loading box (21) and a circular loading plate (22), the loading box (21) is provided with two rows of equally spaced square grooves, and the circular loading plate ( 22) comprises a circular groove plate (23), a V-shaped spring sheet (24), the V-shaped spring sheet (24) is composed of a first spring sheet (25) and a second spring sheet (26), the second spring sheet (26) is connected to the first spring sheet (25) by welding, and a total of 4 V-shaped spring sheets (24) are welded on the edge of the circular groove plate (23) at the same interval angle; the outer diameter of the circular loading plate (22) is equal to the inner width of the square groove of the loading box (21), and can be stuck in the square groove of the loading box (21); the upper surface of the inverted trapezoidal linear guide slider (6) is provided with an inverted trapezoidal guide rail, and the lower surface is provided with an inverted trapezoidal slide groove, and the inverted trapezoidal slide rail on the upper surface of the inverted trapezoidal linear guide slider (6) is perpendicular to the inverted trapezoidal slide groove on the lower surface;The inverted trapezoidal linear guide slider (6) is connected to the object loading platform slide rail (4) via an inverted trapezoidal slide groove on the lower surface; the pull-out object loading box (5) is slidably connected via an inverted trapezoidal guide rail on the upper surface of the inverted trapezoidal linear guide slider (6).

2. A SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The base (1) has a length of 20 cm, a width of 15 cm and a height of 1 cm.

3. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The first support rod (12-1) and the second support rod (12-2) of the support rod (2) have a height of 15 centimeters and a diameter of 1.5 centimeters.

4. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The diameter of the Raman probe fixing hole at the front end of the support frame (17) of the Raman probe bracket (3) is 1.5 cm.

5. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The upper surface of the object-carrying platform slide rail (4) is 12 cm long and 2 cm wide, and the lower surface is 12 cm long and 1.5 cm wide.

6. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The square groove of the object carrying box (21) has a side length of 3 cm and a depth of 0.5 cm.

7. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The grooves on the object carrying box (21) are arranged in two rows, with 7 grooves in each row.

8. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The inner diameter of the groove of the circular groove plate (23) is 2.6 cm, and the depth of the groove is 0.5 cm.

9. The SERS substrate stage for portable Raman spectrometer detection according to claim 1, characterized in that: The height of the first spring piece (25) is 0.5 cm, and the inner angle between the second spring piece (26) and the first spring piece (25) is 40 degrees.

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