Small animal heart slicing device
By designing a small animal heart slice device including a peach-shaped heart accommodating base and a slice knife set composed of a peach-shaped heart accommodating base and a uniformly distributed blade, the problem of cumbersome operation and inaccurate measurement in the prior art is solved, and a fast and uniform heart slice is achieved. Improved the efficiency and accuracy of myocardial infarction range determination.
Patent Information
- Application Number
- CN202420897987.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-26
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2034-04-26
AI Technical Summary
The existing myocardial infarction range measurement methods are cumbersome and time-consuming, and the slice thickness is difficult to control, which affects the accuracy of the measurement.
A small animal heart slicing device is designed, including an upper handle, a lower handle, a heart-receiving base and a slice knife set. The heart storage base is peach-shaped, and the slice knife set consists of multiple evenly distributed blade components, which can quickly and evenly cut heart tissue.
The device is simple in structure and easy to use. It can quickly and evenly cut the heart tissue of small animals, improve the efficiency and accuracy of myocardial infarction range determination, and reduce the displacement or shaking of the heart during the cutting process.
Smart Images

Figure CN222461071U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of animal experimental instruments, in particular to a small animal heart slicing device. Background Art
[0002] In order to explore the pathogenesis, treatment methods and preventive measures of myocardial infarction, researchers need to induce and evaluate myocardial infarction in animal models. Among them, the determination of the scope of myocardial infarction is one of the important indicators for evaluating the degree and effect of myocardial infarction.
[0003] At present, the commonly used method for measuring the scope of myocardial infarction is to mark different areas of the myocardium with different colors, generally the infarcted area is white, then make continuous sections along the short axis of the heart and stain them, measure the area of the white area of each piece of tissue through image analysis software, and finally calculate the total myocardial infarction area of a single heart. The disadvantage of this method is that it requires multiple sections of the heart, which is cumbersome and time-consuming, and the thickness of the sections is difficult to control, which can easily lead to uneven sections and affect the accuracy of the measurement.
[0004] In order to solve the above problems, there are some different heart slicing devices. However, these heart slicing devices still have some shortcomings. For example, the shape of the base mold does not conform to the actual shape of the heart, which easily causes the heart to move or shake during the cutting process; the design of the slicing knife group is too complicated or dense, the manufacturing process requirements are high, the product conversion is difficult, or the sliced heart tissue is difficult to remove from the blade or base. Utility Model Content
[0005] The utility model aims to provide a small animal heart slicing device, which is simple, practical, easy to operate, can quickly and evenly cut the small animal heart tissue, and improves the efficiency and accuracy of myocardial infarction range determination.
[0006] The above-mentioned optimized structure of the utility model is realized by the following technical scheme: a small animal heart slicing device, comprising an upper handle;
[0007] A lower handle, one end of which is hinged to the upper handle, and further comprising a heart accommodating base, which is arranged on the lower handle, and the heart accommodating base is provided with an accommodating cavity for accommodating the heart to be sliced, and the accommodating cavity is peach-shaped;
[0008] A slicing knife set is arranged on the upper handle and is arranged corresponding to the heart accommodating base, and can be pressed with the heart accommodating base to complete slicing of the heart;
[0009] A reset member is arranged between the upper handle and the lower handle.
[0010] In some embodiments, the upper handle comprises an upper handle rod, one end of which is hinged to the lower handle and the other end of which is connected to the slicing knife assembly;
[0011] An upper front pressing piece is arranged at an end of the slicing knife assembly away from the upper handle bar;
[0012] The upper limit groove is arranged near the hinge of the upper handle bar.
[0013] In some embodiments, the lower handle comprises a lower handle rod, one end of which is hinged to the upper handle rod and the other end of which is connected to the heart receiving base;
[0014] A lower front pressing plate, arranged at one end of the heart accommodating base away from the lower handle bar;
[0015] The lower limit groove is arranged near the hinge of the lower handle bar, and the reset member is arranged between the lower limit groove and the upper limit groove.
[0016] In some embodiments, the slicing knife set includes a slicing knife set body, and a through hole is provided in the middle of the slicing knife set body;
[0017] At least 11 blade assemblies are evenly distributed on the inner wall of the through hole, and the blade assembly includes two blade grooves symmetrically arranged on both sides of the through hole;
[0018] A blade, with two ends respectively disposed in the two blade slots;
[0019] The limiting member can realize the fixing of the blade assembly on the slicing knife assembly body.
[0020] In some embodiments, the stopper includes at least six fixing holes, which are symmetrically distributed on both sides of the slicing knife assembly body;
[0021] Two limit buckles are symmetrically distributed on both sides of the slicing knife assembly body, can cover one side of multiple blade assemblies, and can be plugged and matched with the fixing holes.
[0022] In some embodiments, the slicing knife assembly includes two grooves symmetrically arranged on both sides of the slicing knife assembly body, the limiting buckles are arranged in the grooves, and the depth of the grooves is greater than the height of the limiting buckles.
[0023] In some embodiments, the heart receiving base comprises a bottom plate, and a peach-shaped groove is provided on the bottom plate;
[0024] At least 11 cutting grooves are evenly distributed on the peach-shaped groove and correspond to the blades one by one.
[0025] In some embodiments, the upper front pressing piece includes an upper cutting stop block, which is arranged at the connection between the upper front pressing piece and the slicing knife assembly;
[0026] The lower front pressing piece includes a lower stop block, which is arranged at the connection between the lower front pressing piece and the heart accommodating base and is correspondingly arranged with the upper stop block.
[0027] In some embodiments, the reset member includes a U-shaped spring steel sheet, one end of which is fixed to the upper limit groove, and the other end is fixed to the lower limit groove.
[0028] In summary, the utility model has the following beneficial effects:
[0029] The utility model has a simple structure and is easy to use. It can quickly and evenly cut the heart tissue of small animals to obtain even heart cross-section slices, thereby improving the experimental efficiency of scientific researchers and the accuracy of experimental data. The heart holding base is set to a peach shape, which is closer to the shape of the heart, so that the heart can better maintain a stable state in the holding base, reducing the displacement or shaking of the heart during the cutting process. BRIEF DESCRIPTION OF THE DRAWINGS
[0030] Figure 1 It is the front view of the utility model;
[0031] Figure 2 It is a top view of the utility model;
[0032] Figure 3 It is a bottom view of the utility model;
[0033] Figure 4 It is a top view of the heart accommodating base of the utility model;
[0034] Figure 5 It is a side view of the heart accommodating base of the utility model;
[0035] Figure 6 This is a bottom view schematic diagram of the slicing knife assembly of the utility model;
[0036] Figure 7 This is a bottom view of the slicing knife assembly of the utility model without the blade;
[0037] Figure 8 It is a structural schematic diagram of the limit buckle of the utility model.
[0038] In the figure: 1. upper handle; 11. upper handle rod; 12. upper front pressing plate; 13. upper limit groove; 14. upper stop block; 2. lower handle; 21. lower handle rod; 22. lower front pressing plate; 23. lower limit groove; 24. lower stop block; 3. reset member; 4. slicing knife assembly; 41. slicing knife assembly body; 42. blade groove; 43. fixing hole; 44. blade; 45. limit buckle; 5. heart accommodating base; 51. bottom plate; 52. peach-shaped groove; 53. cutting groove. DETAILED DESCRIPTION
[0039] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of them. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0040] like Figure 1-8 As shown, the utility model comprises an upper handle 1, a lower handle 2, a reset member 3, a slicing knife set 4 and a heart accommodating base 5, wherein:
[0041] The lower handle 2 includes a lower handle rod 21, a lower front pressing piece 22 and a heart accommodating base 5. The outer surface of the upper handle rod 11 of the lower handle rod 21 is provided with anti-slip lines, which is convenient for pressing the handle during the slicing process; one end of the lower handle rod 21 is hinged to the upper handle rod 11 and can be connected by a hinge so that the lower handle rod 21 and the upper handle rod 11 can rotate; the other end is connected to the heart accommodating base 5, and a peach-shaped accommodating cavity for accommodating the heart to be sliced is provided on the heart accommodating base 5, so that the accommodating cavity is closer to the shape of the heart, so that the heart can better maintain a stable state in the accommodating base 5, reducing the displacement or shaking of the heart during the cutting process; the lower front pressing piece 22 is arranged at one end of the heart accommodating base 5 away from the lower handle rod 21, and the lower handle rod 21 is provided with a lower limit groove 23 near the hinge.
[0042] The upper handle 1 comprises an upper handle rod 11, an upper front pressing piece 12 and a slicing knife group 4. The outer surface of the upper handle rod 11 is provided with anti-slip lines, which is convenient for exerting force to press the handle during the slicing process; one end of the upper handle rod 11 is hinged with the lower handle 2, and the other end is connected with the slicing knife group 4. The slicing knife group 4 is arranged corresponding to the heart accommodating base 5, and can be pressed with the heart accommodating base 5 to complete the slicing of the heart; the upper front pressing piece 12 is arranged at one end of the slicing knife group 4 away from the upper handle rod 11, and the upper handle rod 11 is provided with an upper limit groove 13 near the hinge; a reset member 3 is provided between the lower limit groove 23 and the upper limit groove 13; the reset member 3 can be a U-shaped spring steel sheet, one end of which is fixed on the upper limit groove 13, and the other end is fixed on the lower limit groove 23; the upper handle rod 11 and the lower handle rod 21 can restore the fixed separation angle after cutting, which is convenient for the next cutting operation; at the same time, the spring steel sheet can be prevented from falling off through the lower limit groove 23 and the upper limit groove 13.
[0043] The slicing knife group 4 includes a slicing knife group body 41, at least 11 blade assemblies and a limiting member. A through hole is provided in the middle of the slicing knife group body 41. The slicing knife group body 41 can be a circular ring. The blade assemblies can be 11. Multiple blade assemblies are evenly distributed on the inner wall of the through hole, and the whole heart can be evenly cut into 0.8-1mm slices. Even if the heart is of different sizes or shapes, we can select the area we need from it; the blade assembly includes a blade slot 42 and a blade 44. The blade slot 42 is symmetrically arranged on both sides of the through hole, and the two ends of the blade 44 are respectively arranged in the blade slot 42. The limiting member includes at least six fixing holes 43, two limiting buckles 45, Multiple fixing holes 43 are symmetrically distributed on both sides of the slicing knife group body 41, and two limiting buckles 45 are symmetrically distributed on both sides of the slicing knife group body 41. The limiting buckle 45 may include an arc plate, which can cover one side of multiple blade assemblies. At least three conical protrusions may be provided on the arc plate, and the conical protrusions can be plugged into and matched with the fixing holes 43, thereby achieving the fixation of the blade assembly on the slicing knife group body 41; a cross groove may be provided in the middle of the conical protrusion, so that when the conical protrusion is interference-fitted with the fixing hole 43, it has a certain elastic performance, thereby achieving a detachable connection between the limiting buckle 45 and the slicing knife group body 41, which is convenient for the replacement of the blade 44.
[0044] Two grooves are symmetrically provided on both sides of the slicing knife group body 41, and a limiting buckle 45 is provided in the groove, and the depth of the groove is greater than the height of the limiting buckle 45, so that when the limiting buckle 45 is embedded in the slicing knife group body 41, no protrusion will be formed to hinder the cutting of the slicing knife group 4 and the heart accommodating base 5.
[0045] The heart accommodating base 5 includes a bottom plate 51, a peach-shaped groove 52, and a cutting groove 53. The bottom plate 51 can be a circular bottom plate with a diameter slightly larger than the main body of the slicing knife group 4. A peach-shaped groove 52 protruding upward is provided in the middle of the bottom plate 51; the peach-shaped groove 52 is set to be heart-shaped, which is different from the uniform elliptical shape of an ordinary heart accommodating groove. Its shape is closer to the shape of a real small animal heart, with a flatter bottom part and a slightly pointed apex part. At the same time, the arc-shaped base design can better fit the heart tissue and minimize the displacement of the heart during the cutting process; a plurality of cutting grooves 53 are evenly arranged in the peach-shaped groove 52, and the cutting grooves 53 can be 11, which correspond one by one to the blade 44 to achieve slicing of the heart.
[0046] The cutting groove 53 may be slightly higher than the bottom of the heart accommodating base 5, so that the heart tissue can be completely cut off to avoid the heart tissue still being connected after cutting, which affects the removal and staining of the slices.
[0047] An upper stop block 14 is provided at the connection between the upper front pressing plate 12 and the slicing knife group 4, and a lower stop block 24 is provided at the connection between the lower front pressing plate 22 and the heart accommodating base 5. The lower stop block 24 is arranged corresponding to the upper stop block 14; during the slicing process, the lower stop block 24 contacts the upper stop block 14 to limit the rotation between the upper handle rod 11 and the lower handle rod 21, thereby preventing the blade 44 from continuing to cut downward, which not only reduces the wear of the blade but also avoids damage to the operator's fingers.
[0048] The width of the cutting groove 53 can be 0.8 mm, the spacing between two adjacent cutting grooves 53 can be 0.2 mm, the thickness of the blade 44 can be 0.2 mm, and the blade can be slightly thinner to facilitate tissue cutting, so that the thickness of the cut heart slice is about 0.8 mm.
[0049] The working principle of the utility model is as follows:
[0050] During use, the frozen heart is placed in the peach-shaped groove 52 of the heart accommodating base 5, the heart position is adjusted to make it fit well, so that the heart will not shake easily, observe the heart surface and touch the heart surface gently with your hand to feel the heart texture, when the heart softens slightly, hold the upper handle bar 11 and the lower handle bar 21 with your left hand at the same time, and place the thumb and index finger of your right hand on the upper front pressing sheet 12 and the lower front pressing sheet 22 respectively, gently force the slicing knife group 4 to just contact the heart surface, cut the heart tissue at a uniform speed, and when you see that the blade enters the spacing of the cutting groove 53, you can increase the strength to completely cut off the heart tissue at one time, and the upper stop block 14 and the lower stop block 24 will touch together at this time, prevent the slicing knife group 4 from excessively cutting the heart tissue, reduce the loss of the blade and avoid the injury to the operator's fingers. After cutting, the elastic effect of the U-shaped spring steel sheet can restore the upper handle 1 and the lower handle 2 to a fixed separation angle, which is convenient for the next cutting operation. The cut heart tissue can be easily taken out from the heart holding base 5, and then the area of the white area of each piece of tissue is measured by image analysis software, and finally the total myocardial infarction area of a single heart is calculated.
[0051] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.
Claims
1. A small animal heart slicing device, comprising an upper handle (1); The lower handle (2) has one end hinged to the upper handle (1), and is characterized in that: It also comprises a heart accommodating base (5) which is arranged on the lower handle (2), and the heart accommodating base (5) is provided with an accommodating cavity for accommodating the heart to be sliced, and the accommodating cavity is peach-shaped; A slicing knife assembly (4) is arranged on the upper handle (1) and is arranged corresponding to the heart accommodating base (5), and can be pressed together with the heart accommodating base (5) to complete slicing of the heart; A reset member (3) is arranged between the upper handle (1) and the lower handle (2).
2. A small animal heart slicing device according to claim 1, characterized in that: The upper handle (1) comprises an upper handle rod (11), one end of which is hinged to the lower handle (2) and the other end of which is connected to the slicing knife assembly (4); An upper front pressing plate (12) is arranged at an end of the slicing knife assembly (4) away from the upper handle rod (11); An upper limit groove (13) is arranged near the hinge of the upper handle bar (11).
3. A small animal heart slicing device according to claim 2, characterized in that: The lower handle (2) comprises a lower handle rod (21), one end of which is hinged to the upper handle rod (11) and the other end of which is connected to the heart accommodating base (5); A lower front pressing plate (22) is arranged at one end of the heart accommodating base (5) away from the lower handle bar (21); A lower limit groove (23) is arranged near the hinge of the lower handle bar (21), and the reset member (3) is arranged between the lower limit groove (23) and the upper limit groove (13).
4. The small animal heart slicing device according to claim 1, characterized in that: The slicing knife group (4) comprises a slicing knife group body (41), and a through hole is provided in the middle of the slicing knife group body (41); At least 11 blade assemblies are evenly distributed on the inner wall of the through hole, and the blade assembly includes two blade grooves (42) symmetrically arranged on both sides of the through hole; A blade (44), two ends of which are respectively arranged in the two blade grooves (42); The limiting member can realize the fixing of the blade assembly on the slicing knife assembly body (41).
5. The small animal heart slicing device according to claim 4, characterized in that: The limiting member comprises at least six fixing holes (43) symmetrically distributed on both sides of the slicing knife assembly body (41); Two limit buckles (45) are symmetrically distributed on both sides of the slicing knife assembly body (41), can cover one side of a plurality of blade assemblies, and can be plugged into and matched with the fixing holes (43).
6. The small animal heart slicing device according to claim 5, characterized in that: The slicing knife assembly (4) comprises two grooves symmetrically arranged on both sides of the slicing knife assembly body (41), the limiting buckles (45) are arranged in the grooves, and the depth of the grooves is greater than the height of the limiting buckles (45).
7. The small animal heart slicing device according to claim 4, characterized in that: The heart accommodating base (5) comprises a bottom plate (51), and a peach-shaped groove (52) is provided on the bottom plate (51); At least 11 cutting grooves (53) are evenly distributed on the peach-shaped groove (52) and correspond one to one with the blades (44).
8. The small animal heart slicing device according to claim 3, characterized in that: The upper front pressing piece (12) comprises an upper cutting stop block (14) which is arranged at the connection between the upper front pressing piece (12) and the slicing knife assembly (4); The lower front pressing piece (22) comprises a lower stop block (24), which is arranged at the connection between the lower front pressing piece (22) and the heart accommodating base (5) and is arranged corresponding to the upper stop block (14).
9. The small animal heart slicing device according to claim 3, characterized in that: The reset member (3) comprises a U-shaped spring steel sheet, one end of which is fixed on the upper limit groove (13) and the other end of which is fixed on the lower limit groove (23).