Immunoassay microwell plate sample adding auxiliary device

Abstract

The utility model relates to the field of immune test microwell plate sample adding, and discloses an immune test microwell plate sample adding auxiliary device which comprises a sample storage box body, a cover plate is arranged at the top end of the sample storage box body, a microwell plate body is arranged on the inner wall of the sample storage box body, and a dispersing assembly is arranged on the inner wall of the sample storage box body. The dispersing assembly comprises a guide frame, a second sliding groove is formed in the left side of the guide frame, a first sliding groove is formed in the position, close to the lower portion of the second sliding groove, of the left side of the guide frame, a limiting groove is formed in the front surface of the guide frame, and the guide frame is slidably connected to the inner wall of the sample storage box body. According to the microplate disclosed by the utility model, the microplate bodies are driven by the guide frame to move upwards, so that the multiple groups of microplate bodies can be mutually dispersed when moving upwards, the distance between adjacent hole sites among the multiple groups of microplate bodies is increased, the sample adding is more convenient by increasing the distance, the sample pollution during sample adding is reduced, and the sample adding efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the field of immunoassay microplate sample addition, in particular to an immunoassay microplate sample addition auxiliary device. Background Art

[0002] In immunoassays, microplates are commonly used as experimental equipment and are widely used in the detection and analysis of antigens and antibodies. Microplates are usually composed of multiple tiny holes or grooves, which are used to carry samples or reagents for subsequent immune reactions and detection. However, due to the dense arrangement of the microplate body, operators often face many challenges when adding samples.

[0003] First, the dense arrangement of microplate wells increases the difficulty of sample loading operations. Operators need to accurately add samples or reagents to the corresponding wells, and the narrow spacing between the wells makes this task extremely difficult. In addition, prolonged sample loading operations may cause hand fatigue, which in turn affects the stability and accuracy of the operation.

[0004] After searching, Chinese patent announcement number: CN220478875U discloses an immunoassay microplate loading auxiliary device, including a main body mechanism and a convenient mechanism, the convenient mechanism is located at the lower end of the main body mechanism, the main body mechanism includes a sample storage box, a slide slot 1 and a telescopic upper cover, the slide slot 1 is fixedly arranged at the left and right ends of the inner end of the sample storage box, the telescopic upper cover is movably installed in the middle of the slide slot 1, the telescopic upper cover is located at the upper end of the sample storage box, the main body mechanism also includes a handle, a mounting slot and an adjustment component, the handle is fixedly installed at the upper end of the telescopic upper cover. The immunoassay microplate loading auxiliary device improves the adjustment ability of the utility model through the installation and improvement of the main body mechanism. In actual use, the height of the microplate body can be conveniently adjusted according to the loading needs, which improves the market competitiveness of the immunoassay microplate loading auxiliary device.

[0005] In the above technology, the distance between the microplates is also relatively dense, and the operator also needs to be extra careful during the sample addition process to avoid dripping the sample liquid into adjacent wells, causing sample confusion or cross-contamination. Therefore, an immunoassay microplate sample addition auxiliary device is proposed to solve the above problem. Utility Model Content

[0006] In order to make up for the above deficiencies, the utility model provides an immunoassay microplate sample loading auxiliary device, which aims to improve the problem in the prior art that "the spacing between microplates is small, and samples are easily dripped into adjacent wells during loading, causing sample confusion and sample contamination."

[0007] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: an immunoassay microplate sample loading auxiliary device, comprising a sample storage box, a cover plate is arranged on the top of the sample storage box, a microplate body is arranged on the inner wall of the sample storage box, a dispersion component is arranged on the inner wall of the sample storage box, the dispersion component comprises a guide frame, a slide groove 2 is arranged on the left side of the guide frame, a slide groove 1 is arranged on the left side of the guide frame near the bottom of the slide groove 2, a limiting groove is arranged on the front surface of the guide frame, the guide frame is slidably connected to the inner wall of the sample storage box, a pull rod is fixedly connected to the top of the guide frame, and a guide rod is slidably connected to the inner wall of the slide groove 1.

[0008] As a further description of the above technical solution:

[0009] A supporting assembly is arranged at the bottom end of the cover plate. The supporting assembly comprises a positioning frame. The positioning frame is fixedly connected to the middle part of the bottom end of the cover plate.

[0010] As a further description of the above technical solution:

[0011] The front surface of the sample storage box is penetrated and slidably connected with a limiting rod, and the guide rod is fixedly connected to the right side of the microplate body.

[0012] As a further description of the above technical solution:

[0013] A guide groove is provided on the right inner wall of the sample storage box, and the guide rod is slidably connected to the inner wall of the guide groove.

[0014] As a further description of the above technical solution:

[0015] The limiting rod is elastically connected to the sample storage box through a second spring, and the limiting rod slides on the inner wall of the limiting groove.

[0016] As a further description of the above technical solution:

[0017] A pressing plate is slidably connected to the bottom end of the inner wall of the positioning frame, and the pressing plate is elastically connected to the positioning frame through a spring.

[0018] As a further description of the above technical solution:

[0019] A slider is fixedly connected to the right side of the microplate body near the top of the guide rod. The microplate body, guide rod and slider are arranged in multiple groups, and the multiple groups of microplate bodies, guide rods and sliders are symmetrically arranged with the center line of the sample storage box as the symmetry axis.

[0020] As a further description of the above technical solution:

[0021] The sliding block is slidably connected to the inner wall of the second slide groove, and two groups of guide frames are provided. The two groups of guide frames are symmetrically arranged with the center line of the sample storage box as the symmetry axis.

[0022] The utility model has the following beneficial effects:

[0023] 1. In the utility model, the guide frame is driven to move by moving the pull rod, and the microplate body is driven to move upward by the guide frame. The guide groove, the guide rod, the slider and the slide groove can make multiple groups of microplate bodies spread out from each other when they move upward, thereby increasing the distance between adjacent wells between multiple groups of microplate bodies. By increasing the distance, it is more convenient to add samples, and at the same time, the sample contamination is reduced during the addition of samples, thereby improving the addition efficiency.

[0024] 2. In the utility model, the sample storage box is protected by rotating the cover plate, and the cover plate is rotated to drive the pressing plate to contact the microplate body for protection. At the same time, the pressing plate cooperates with the spring to always limit the microplate body, thereby improving the stability of the microplate body when moving. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a three-dimensional structural schematic diagram of the overall device in the utility model;

[0026] Figure 2 It is a schematic left side view of the three-dimensional structure section of the sample storage box in the utility model;

[0027] Figure 3 It is a right side schematic diagram of the three-dimensional structure of the sample storage box in the utility model;

[0028] Figure 4 It is a schematic diagram of the three-dimensional structure of the cover plate, the positioning frame and the guide frame in the utility model;

[0029] Figure 5 It is a top view schematic diagram of the three-dimensional structure of the sample storage box in the utility model.

[0030] Legend:

[0031] 1. Sample storage box; 2. Cover plate; 3. Pull rod; 21. Positioning frame; 22. Press plate; 23. Spring 1; 31. Limit rod; 32. Guide frame; 33. Slide groove 1; 34. Microplate body; 35. Guide groove; 36. Spring 2; 37. Slider; 38. Slide groove 2; 39. Guide rod; 310. Limit groove. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0033] Reference Figure 3 , Figure 4 , Figure 5 The utility model provides an embodiment: an immunoassay microplate sample loading auxiliary device, including a sample storage box 1, in which samples can be stored, a cover plate 2 is arranged on the top of the sample storage box 1, and the cover plate 2 can be used for protection, and a microplate body 34 is arranged on the inner wall of the sample storage box 1, and the microplate body 34 can be used to carry samples or reagents, and a dispersion component is arranged on the inner wall of the sample storage box 1, and the dispersion component includes a guide frame 32, and the guide frame 32 can drive the guide rod 39 and the microplate body 34 to move, and a slide groove 2 38 is opened on the left side of the guide frame 32, and the slider 37 slides in the slide groove 2 38 to support the microplate body 34 to prevent the microplate body 34 from rotating.

[0034] Furthermore, a slide groove 1 33 is provided on the left side of the guide frame 32 near the bottom of the slide groove 2 38. The movement of the guide frame 32 can drive the movement of the slide groove 1 33, thereby driving the guide rod 39 and the microwell plate body 34 to move. A limiting groove 310 is provided on the front surface of the guide frame 32. The limiting rod 31 slides into the limiting groove 310 to limit the guide frame 32. The guide frame 32 is slidably connected to the inner wall of the sample storage box 1, and the guide frame 32 is supported by the sample storage box 1. The top of the guide frame 32 is fixedly connected with a pull rod 3, and the guide frame 32 is driven to move by the pull rod 3. The inner wall of the slide groove 1 33 is slidably connected with a guide rod 39, and the guide rod 39 can drive the microwell plate body 34 to move.

[0035] Reference Figure 1 , Figure 4 A support assembly is provided at the bottom end of the cover plate 2, and the support assembly includes a positioning frame 21, the positioning frame 21 supports a spring 23 and a pressing plate 22, and the positioning frame 21 is fixedly connected to the middle part of the bottom end of the cover plate 2.

[0036] Reference Figure 2 , Figure 4 , Figure 5The front surface of the sample storage box 1 passes through and is slidably connected to a limit rod 31, and a guide rod 39 is fixedly connected to the right side of the microplate body 34. The microplate body 34 can be driven to move by the guide rod 39. A guide groove 35 is provided on the right inner wall of the sample storage box 1. The guide groove 35 is provided with a plurality of groups corresponding to the number of the microplate bodies 34. At the same time, the plurality of groups of guide grooves 35 are arranged in an inclined state of spreading outward, so that the guide rod 39 can slide in the guide groove 35 to make the plurality of groups of microplate bodies 34 spread outward, thereby increasing the distance between the plurality of groups of microplate bodies 34, which is convenient for sample addition operation, and the guide rod 39 is slidably connected to the inner wall of the guide groove 35.

[0037] Furthermore, the limiting rod 31 is elastically connected to the sample storage box 1 via a spring 2 36. The limiting rod 31 slides on the inner wall of the limiting groove 310, and can drive the limiting groove 310 to move when the guide frame 32 is moved upward. When the microplate body 34 is moved to the top, the guide frame 32 squeezes the inclined surface of the limiting rod 31, causing the limiting rod 31 to move inward and outward to stretch the spring 2 36. The reverse force of the stretched spring 2 36 can make the limiting rod 31 slide into the limiting groove 310, thereby limiting the guide frame 32. At this time, the microplate body 34 can be limited, which is convenient for sample loading.

[0038] Reference Figure 1 , Figure 3 , Figure 4 The bottom end of the inner wall of the positioning frame 21 is slidably connected with a pressing plate 22, and the pressing plate 22 and the positioning frame 21 are elastically connected by a spring 23. The microporous plate body 34 is supported and limited by the pressing plate 22, and at the same time, with the elastic performance of the spring 23, the pressing plate 22 can always limit the microporous plate body 34 and play a buffering role, thereby protecting the microporous plate body 34.

[0039] Reference Figure 3 - Figure 5 A slider 37 is fixedly connected to the right side of the microplate body 34 near the top of the guide rod 39. The microplate body 34, the guide rod 39, and the slider 37 are provided in multiple groups. The multiple groups of microplate bodies 34, the guide rod 39, and the slider 37 are symmetrically arranged with the center line of the sample storage box 1 as the axis of symmetry. Multiple groups are set to correspond to multiple groups of microplate bodies 34, so that the multiple groups of microplate bodies 34 can be moved, which is convenient for sample addition. The slider 37 is slidably connected to the inner wall of the second slide groove 38. The sliding of the slider 37 on the inner wall of the second slide groove 38 can increase the stability of the microplate body 34 and prevent the possibility of rotation when it is moved only by the guide rod 39, thereby increasing stability. There are two groups of guide frames 32. The two groups of guide frames 32 are symmetrically arranged with the center line of the sample storage box 1 as the axis of symmetry. The two groups of guide frames 32 increase the stability of movement.

[0040] Working principle: when in use, by opening the fixed plate-cover plate 2, the shift block positioning frame 21, the limit block spring 23, and the positioning block-pressing plate 22 are driven to rotate, and the limit of the microporous plate body 34 is released. At this time, the fixed plate second pull rod 3 can be moved upward to drive the guide frame 32 to move upward, and the guide frame 32 moves upward to drive the guide rod 39 and the slider 37 to move upward, and the guide rod 39 is slidably connected to the inner wall of the slide groove 33 and the inner wall of the guide groove 35. At the same time, the guide groove 35 is set to an inclined shape, so that the guide rod 39 can move upward and move outward along the inclined guide groove 35 at the same time, and the microporous plate body 34 can be moved upward and outward at the same time by the guide rod 39 moving upward and outward at the same time, so that multiple groups of microporous plate bodies 34 and multiple groups of guide grooves 35 can make multiple groups of microporous plate bodies 34 move upward and disperse from each other at the same time, thereby increasing the distance between multiple groups of microporous plate bodies 34.

[0041] Furthermore, the guide frame 32 moves to contact the inclined surface of the limit rod 31 and squeezes the limit rod 31, so that the limit rod 31 moves outward to stretch the second spring 36. The reverse force of the stretched second spring 36 can drive the limit rod 31 to reset and slide into the limit groove 310 to limit the guide frame 32. At this time, the distance between the microplate bodies 34 can be increased, which can make sample addition more convenient, reduce sample contamination during sample addition, and improve sample addition efficiency. At the same time, the slider 37 sliding in the second slide groove 38 can increase the stability of the microplate body 34.

[0042] When the sample addition is completed, pull the limit rod 31 to slide out of the limit groove 310 to release the limit of the guide frame 32. At this time, move the fixed plate and the second pull rod 3 downward to drive the guide frame 32 to move downward so that multiple groups of microplate bodies 34 are reset and stored in the bracket sample storage box 1. At this time, the fixed plate and the cover plate 2 can be rotated to drive the shift block positioning frame 21, the limit block spring 23, and the positioning block and the pressing plate 22 to rotate. When the positioning block and the pressing plate 22 are rotated to contact the microplate body 34, the microplate body 34 can be supported and limited by the positioning block and the pressing plate 22 and the limit block spring 23, thereby improving the stability of the microplate body 34 and the safety of the microplate body 34 when the bracket sample storage box 1 is moved.

[0043] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An immunoassay microplate sample loading auxiliary device, comprising a sample storage box (1), characterized in that: The top of the sample storage box (1) is provided with a cover plate (2), the inner wall of the sample storage box (1) is provided with a microplate body (34), the inner wall of the sample storage box (1) is provided with a dispersion component, and the dispersion component includes a guide frame (32), the left side of the guide frame (32) is provided with a second slide groove (38), the left side of the guide frame (32) is provided with a slide groove (33) below the second slide groove (38), the front surface of the guide frame (32) is provided with a limiting groove (310), the guide frame (32) is slidably connected to the inner wall of the sample storage box (1), the top of the guide frame (32) is fixedly connected with a pull rod (3), and the inner wall of the slide groove (33) is slidably connected with a guide rod (39).

2. The immunoassay microplate sample loading auxiliary device according to claim 1, characterized in that: A support assembly is provided at the bottom end of the cover plate (2), and the support assembly comprises a positioning frame (21). The positioning frame (21) is fixedly connected to the middle part of the bottom end of the cover plate (2).

3. The immunoassay microplate sample loading auxiliary device according to claim 1, characterized in that: A limiting rod (31) penetrates and is slidably connected to the front surface of the sample storage box (1), and the guide rod (39) is fixedly connected to the right side of the microplate body (34).

4. The immunoassay microplate sample loading auxiliary device according to claim 1, characterized in that: A guide groove (35) is provided on the right inner wall of the sample storage box (1), and the guide rod (39) is slidably connected to the inner wall of the guide groove (35).

5. The immunoassay microplate sample loading auxiliary device according to claim 3, characterized in that: The limiting rod (31) is elastically connected to the sample storage box (1) via a second spring (36), and the limiting rod (31) slides on the inner wall of the limiting groove (310).

6. The immunoassay microplate sample loading auxiliary device according to claim 2, characterized in that: A pressing plate (22) is slidably connected to the bottom end of the inner wall of the positioning frame (21), and the pressing plate (22) is elastically connected to the positioning frame (21) via a spring (23).

7. The immunoassay microplate sample loading auxiliary device according to claim 5, characterized in that: A slider (37) is fixedly connected to the upper side of the right side of the microplate body (34) near the guide rod (39), and the microplate body (34), the guide rod (39), and the slider (37) are provided in multiple groups, and the multiple groups of microplate bodies (34), guide rods (39), and sliders (37) are symmetrically arranged with the center line of the sample storage box (1) as the symmetry axis.

8. The immunoassay microplate sample loading auxiliary device according to claim 7, characterized in that: The slide block (37) is slidably connected to the inner wall of the second slide groove (38), and two groups of guide frames (32) are provided. The two groups of guide frames (32) are symmetrically arranged with the center line of the sample storage box (1) as the symmetry axis.

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