Pathological tissue slicing device

Abstract

The utility model discloses a pathological tissue slicing device, which particularly belongs to the technical field of pathological tissue research and comprises a bottom fixing plate, a sliding frame, a blade, a fixing frame and a driving part for driving pathological tissues to be fixed up and down, the sliding frame is arranged on the bottom fixing plate in a sliding mode, and the blade is fixed to the upper end of the sliding frame. The pathological tissue is embedded and fixed in the fixing frame; the driving piece is in transmission connection with the fixing frame. The pathological tissue slicing device is small in size and convenient for workers to use in different environments. Meanwhile, a worker can directly apply force to the fixed sample to enable the sample to move up and down, and after the sample is in contact with the blade, a pathological tissue paraffin section is obtained.

Description

Technical Field

[0001] The utility model belongs to the technical field of pathological tissue research, and in particular relates to a pathological tissue slicing device. Background Art

[0002] Pathological testing can help doctors determine the type and nature of the disease by observing the morphology, cytology and immunohistochemistry of the diseased tissue. This is crucial for determining the treatment plan and predicting the progression of the disease. Chinese utility model application No. 2022226850337 discloses a pathological tissue slicing device for small animal experiments. The pathological tissue slicing device mainly improves the clamping part so that it can clamp and fix samples of different specifications.

[0003] In the laboratory, the sizes of paraffin samples of pathological tissues are almost the same, because what we want is paraffin slices with pathological tissues, and the paraffin wrapped around them can be completely cut off. However, both the above patent application and the existing slicers have the following disadvantages when in use: 1. The entire paraffin slicer occupies a large area, which is not conducive to the use of staff in different experimental environments. 2. When controlling the up and down movement of the pathological tissue sample, it is achieved by turning the handle wheel by hand to control the upper movement of the clamp holding the paraffin sample. In fact, the operation is also more troublesome. Summary of the invention

[0004] The utility model aims to provide a pathological tissue slicing device, which is small in size and convenient for workers to use in different environments. At the same time, the workers can directly apply force to the fixed sample to make it move up and down, and obtain pathological tissue paraffin slices after contacting the blade.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A pathological tissue slicing device comprises a bottom fixing plate, a sliding frame, a blade, a fixing frame and a driving member for driving the pathological tissue to be fixed up and down;

[0007] The sliding frame is slidably arranged on the bottom fixed plate, and the blade is fixed to the upper end of the sliding frame;

[0008] The pathological tissue is embedded in a fixation frame and fixed;

[0009] The driving member is drivingly connected to the fixed frame.

[0010] The sliding frame is slidably mounted on the bottom fixed plate and is used to adjust the distance between the blade and the paraffin sample of the pathological tissue. By controlling this distance, the thickness of the paraffin section can be controlled.

[0011] The driving part is set to control the up and down movement of the paraffin sample of pathological tissue. When the paraffin sample of pathological tissue moves up and down and contacts the blade, a thin slice will be cut. The principle is the same as that of the existing microtome. The pathological tissue sample obtained by the slice is spread flat on warm water, and the surface tension of water can be used to carry out the next step of the slice spreading operation.

[0012] Preferably, the driving member includes a sleeve, a spring and an "L"-shaped connecting rod; a receiving groove is provided at the upper end of the bottom fixing plate, and the sleeve is fixed in the receiving groove; a fixing ring is provided at the side end of the "L"-shaped connecting rod, and the spring is sleeved on the outside of the sleeve, with one end fixed to the bottom of the receiving groove and the other end fixed to the fixing ring; the "L"-shaped connecting rod is slidably connected to the sleeve.

[0013] After the paraffin sample of the pathological tissue is fixedly installed in the fixed frame, the position of the sliding block and the sliding frame is adjusted so that the blade and the paraffin sample of the pathological tissue are at a suitable distance, and then pressure can be applied downward to the "L"-shaped connecting rod. Due to the action of the spring, the "L"-shaped connecting rod moves downward, and its end extends into the sleeve. At this time, when the staff stops applying force, the spring rebounds, causing the "L"-shaped connecting rod to move upward. The paraffin sample is in continuous contact with the blade during the up and down reciprocating motion, thereby obtaining sample slices. And after obtaining partial slices, if the staff still needs to prepare slices, the position of the sliding frame can be adjusted again so that the blade and the pathological tissue sample are at a suitable distance again, and the pathological tissue can be driven up and down again to achieve re-slicing.

[0014] Preferably, the driving member further comprises a connecting rod and a handle, one end of the connecting rod is fixed to the “L”-shaped connecting rod, and the other end is fixed to the handle.

[0015] The function of the handle is to make it easier for the staff to apply force up and down.

[0016] Preferably, the sliding frame comprises a sliding block, a fixed connecting rod and a blade fixing frame;

[0017] The upper end of the bottom fixing plate is provided with a sliding groove, and the lower end of the sliding block is provided with a protrusion adapted to slide in the sliding groove; one end of the fixed connecting rod is fixed to the upper end of the sliding block, and the other end is fixed to the blade fixing frame, and the blade is embedded in the blade fixing frame.

[0018] The sliding block is slidably connected to the bottom fixing plate, and can be used to adjust the distance between the blade and the pathological tissue sample. When the distance between the two is adjusted, the locking bolt is tightened so that the end of the sliding block is pressed against the side of the bottom fixing plate, thereby fixing the sliding block to avoid movement during slicing.

[0019] Preferably, the sliding frame further comprises a locking rod and a locking bolt, the locking rod is fixed to the side end of the sliding block, and the free end of the locking rod is provided with a threaded hole adapted to the locking bolt.

[0020] Preferably, a groove for fixing the pathological tissue is provided on the fixing frame, and a fixing block is provided at the upper end of the groove, and the block is tightly pressed against the pathological tissue.

[0021] The paraffin wax sample of pathological tissue is in the shape of a regular quadrilateral and can be directly inserted into the groove, and the opening of the groove is pressed tightly by a fixed block. Since the paraffin wax sample of pathological tissue is in contact with the blade during the up and down movement, the setting of the fixed block can prevent the paraffin wax sample of pathological tissue from being taken out during slicing.

[0022] Preferably, the fixed block is provided with a paddle for the convenience of the staff in turning it.

[0023] Preferably, scales are provided on both sides of the sliding groove. The scales are provided to facilitate the staff to judge the distance between the blade and the pathological tissue sample, thereby facilitating the determination of the thickness of the slices and obtaining slices that meet the regulations.

[0024] Preferably, the driving member further comprises a fixing rod, one end of which is fixed to the fixing frame, and the other end of which is fixed to the “L”-shaped connecting rod.

[0025] Compared with the prior art, the beneficial effects of the utility model are:

[0026] 1. A test bench with a simple structure, applicable to more scenarios, and takes up less space.

[0027] 2. It is more labor-saving to use, and the slicing process is more intuitive. The integrity and thickness of the slices can be clearly observed, so that the staff can make timely adjustments. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 This is a diagram of the pathological tissue sectioning device in use (side view);

[0029] Figure 2 It is a schematic diagram of the structure of the pathological tissue slicing device.

[0030] In the figure: 1, handle, 2, connecting rod, 3, fixing frame, 4, "L"-shaped connecting rod, 5, fixing ring, 6, spring, 7, sleeve, 8, bottom fixing plate, 9, locking rod, 10, locking bolt, 11, sliding groove, 12, scale, 13, fixed connecting rod, 14, paddle, 15, blocking block, 16, blade, 17, blade fixing frame, 18, sliding block, 20, pathological tissue. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Example

[0032] Based on the above description, this embodiment further explains the pathological tissue slicing device from the perspective of application:

[0033] The main part of the pathological tissue sectioning device includes:

[0034] Bottom fixing plate 8;

[0035] Sliding rack;

[0036] The sliding frame includes: a sliding block 18, a fixed connecting rod 13, a blade fixing frame 17, a locking rod 9 and a locking bolt 10;

[0037] Blade 16;

[0038] Fixed frame 3;

[0039] Driving parts;

[0040] The driving member includes a sleeve 7, a spring 6, an "L"-shaped connecting rod 4, a connecting rod 2, a handle 1 and a fixing rod.

[0041] In this embodiment, there are two important steps to complete the slicing process: (1) Controlling the slice thickness by adjusting the distance between the blade 16 and the pathological tissue sample. (2) The pathological tissue needs to be fixed to prevent it from coming out after contacting the blade.

[0042] For (1), the staff can use the scale to help move the blade position, so as to achieve more accurate control of the slice thickness. If there is a problem with the slice thickness, it can be adjusted in time, which is also very intuitive.

[0043] For (2), a fixed block is used to seal the groove, and the lower end of the fixed block is tightly pressed against the paraffin sample of the pathological tissue, which can prevent the pathological tissue from moving when it contacts the blade. At the same time, since the texture of the paraffin slice itself is not hard, the use of a fixed block to seal the groove can achieve the purpose of preventing accidental movement of the sample.

Claims

1. A pathological tissue slicing device, characterized in that: It comprises a bottom fixing plate (8), a sliding frame, a blade (16), a fixing frame (3), and a driving member for driving the pathological tissue (20) to be fixed up and down; The sliding frame is slidably arranged on the bottom fixing plate (8), and the blade (16) is fixed to the upper end of the sliding frame; The pathological tissue (20) is embedded in a fixing frame (3) and fixed; The driving member is drivingly connected to the fixed frame (3).

2. The pathological tissue slicing device according to claim 1, characterized in that: The driving member comprises a sleeve (7), a spring (6) and an "L"-shaped connecting rod (4); The upper end of the bottom fixing plate (8) is provided with a receiving groove, and the sleeve (7) is fixed in the receiving groove; A fixing ring (5) is provided at the side end of the "L"-shaped connecting rod (4), and the spring (6) is sleeved on the outside of the sleeve (7), with one end fixed to the bottom of the receiving groove and the other end fixed to the fixing ring (5); The "L"-shaped connecting rod (4) is slidably connected to the sleeve (7).

3. The pathological tissue slicing device according to claim 2, characterized in that: The driving member also includes a connecting rod (2) and a handle (1); one end of the connecting rod (2) is fixed to the "L"-shaped connecting rod (4), and the other end is fixed to the handle (1).

4. The pathological tissue slicing device according to claim 1, characterized in that: The sliding frame comprises a sliding block (18), a fixed connecting rod (13) and a blade fixing frame (17); The upper end of the bottom fixing plate (8) is provided with a sliding groove (11), and the lower end of the sliding block (18) is provided with a protrusion adapted to slide in the sliding groove (11); One end of the fixed connecting rod (13) is fixed to the upper end of the sliding block (18), and the other end is fixed to the blade fixing frame (17), and the blade (16) is embedded in the blade fixing frame (17).

5. The pathological tissue slicing device according to claim 4, characterized in that: The sliding frame also includes a locking rod (9) and a locking bolt (10). The locking rod (9) is fixed to the side end of the sliding block (18), and the free end of the locking rod (9) is provided with a threaded hole adapted to the locking bolt (10).

6. The pathological tissue slicing device according to claim 2, characterized in that: A groove for fixing the pathological tissue (20) is provided on the fixing frame (3), and a fixing block (15) is provided at the upper end of the groove, and the fixing block (15) is tightly pressed against the pathological tissue (20).

7. The pathological tissue slicing device according to claim 6, characterized in that: The fixed block (15) is provided with a paddle (14) for the convenience of staff to paddle.

8. The pathological tissue slicing device according to claim 6, characterized in that: Scales (12) are provided on both sides of the sliding groove (11).

9. The pathological tissue slicing device according to claim 2, characterized in that: The driving member also includes a fixing rod, one end of which is fixed to the fixing frame (3), and the other end of which is fixed to the "L"-shaped connecting rod (4).

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