Cryopreservation tube storage structure

Abstract

The utility model provides a cryopreservation tube storage structure which is installed on a rotating shaft of a rotary cryopreservation frame and comprises a bracket and at least one hole disc. Wherein the bracket is provided with a hole disc and is connected with the slewing mechanism. The bracket and the hole disc are each provided with at least one receding groove, the hole disc is further provided with a plurality of sector ring areas, and through holes are densely formed in each sector ring area and used for containing cryopreservation tubes. The receding groove is located between the two sector ring areas, and the radial length of the receding groove is larger than the side edge length of the sector ring areas. Multiple circles of through holes are formed in the sector ring area in the radial direction, the through holes in each circle are evenly distributed in the circumferential direction, and the through holes in every two adjacent circles are distributed in a staggered mode in the radial direction. Through the combination of the hole disc and the bracket and the combination of the receding groove and the rotary mechanism, the basic storing and taking function is achieved, the single-pipe storing and taking capacity is achieved in the mode of densely arranging the through holes, the space utilization rate is increased by adopting the reasonable arrangement mode, and the overall storage capacity is also improved.

Description

Technical Field

[0001] The present application belongs to the technical field of deep cryopreservation, and specifically relates to a cryopreservation tube storage structure. Background Art

[0002] Cryopreservation is a technology that can preserve organic substances such as organisms, living tissues, or cells at extremely low temperatures. Generally speaking, cryopreservation can theoretically stop all biological activities, including some biochemical activities that will cause cell death; therefore, biological sample banks that apply cryopreservation technology are currently important basic equipment for research in the medical and biological fields. Cryopreservation can keep biological tissues such as blood, stem cells and immune cells active for a long time.

[0003] At present, in order to realize the centralized placement of samples, the existing cryogenic sample library mostly adopts the design of stacked storage racks, and for the convenience of storage and retrieval, the freezing rack is designed to be a rotary structure. The above design can accurately store and retrieve samples under the guidance of polar coordinates through the clamping mechanism.

[0004] However, the existing freezing racks adopt a whole-box storage and retrieval design, which not only has a complex shelf structure, but also lacks the ability to store and retrieve single tubes; at the same time, the space design and structural characteristics lead to insufficient space utilization, which in turn leads to low effective storage capacity of the equipment.

[0005] In summary, we propose a cryopreservation tube storage structure for a deep-temperature refrigerator to achieve single-tube storage and retrieval operations and improve operational convenience. Utility Model Content

[0006] In view of the problems existing in the prior art, the present application provides a cryotube storage structure to solve the above problems.

[0007] To achieve the above objectives, the technical solutions adopted in this application are as follows:

[0008] The present application provides a cryotube storage structure, which is installed on the rotating shaft of a rotary cryostat, and includes a bracket and at least one hole plate; the hole plate is installed on the bracket, and the bracket and / or the hole plate is connected to a rotary mechanism;

[0009] At least one avoidance groove is provided on each of the bracket and the orifice plate, and the avoidance groove vertically connects the upper part of the orifice plate and the lower part of the bracket;

[0010] The perforated plate is provided with a plurality of sector ring areas, each of which is densely packed with through holes for placing cryotubes;

[0011] The through holes in the sector ring area have a total of multiple circles along the radial direction, and the through holes in each circle are evenly distributed along the circumferential direction; the through holes in two adjacent circles are staggered in the radial direction.

[0012] Optionally, the numbers of two adjacent circles of through holes in each of the fan ring areas are different, and the difference between the number of through holes in an outer circle and the number of through holes in an inner circle along the radial direction is greater than or equal to 2.

[0013] Optionally, the avoidance groove is in a square strip structure, is located between two fan ring areas, and the radial length of the avoidance groove is greater than the side length of the fan ring area.

[0014] Optionally, the orifice plate has two layers, including a first orifice plate and a second orifice plate, and the two orifice plates are stacked and mounted on the bracket by bolts.

[0015] Optionally, a bolt sleeve is provided between the first hole plate and the second hole plate; a bolt sleeve is also provided between the second hole plate and the bracket;

[0016] The bolt sleeve is sleeved on the bolt and is used to separate the orifice plate and the bracket.

[0017] Optionally, the bracket is in the shape of a disc, with a gear ring disposed on the outer side;

[0018] The ring gear is connected to the rotary mechanism.

[0019] Optionally, the rotary mechanism is provided with a driving gear which meshes with the ring gear.

[0020] Optionally, a retaining ring is provided on the outer side of the bracket, and the gear ring is installed on the outer side or lower part of the retaining ring.

[0021] Optionally, a limiting structure is also provided on the retaining ring.

[0022] Optionally, the bracket and the orifice plate are provided with mounting through holes at their centers, and are connected to the rotating shaft;

[0023] At least one keyway is also provided on the peripheral side of the mounting through hole.

[0024] Compared with the prior art, this application has the following beneficial effects:

[0025] The present application realizes the basic storage and retrieval function through the combination of a hole plate and a bracket, combined with the application of a avoidance groove and a rotating mechanism, and realizes the ability of single-tube storage and retrieval by means of closely arranged through holes. The reasonable arrangement method increases the space utilization and improves the overall storage capacity. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0027] Figure 1 It is a stereogram in a specific embodiment of the present application;

[0028] Figure 2 It is a partial cross-sectional view of a specific embodiment of the present application.

[0029] In the figure: 1-hole plate; 2-bracket; 3-gear ring; 4-limiting structure; 5-bolt; 6-bolt sleeve; 101-first hole plate; 102-second hole plate. DETAILED DESCRIPTION

[0030] In order to make the purpose, technical solutions and advantages of the implementation methods of this application clearer, the technical solutions in the implementation methods of this application will be clearly and completely described below in conjunction with the drawings in the implementation methods of this application. Obviously, the described implementation methods are part of the implementation methods of this application, not all of the implementation methods. Based on the implementation methods in this application, all other implementation methods obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0031] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0032] In the description of the present application, it should be understood that the relative relationships indicated by the terms "upper" and "lower" are based on the comparison results of parameters in actual applications, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific numerical range, and therefore cannot be understood as a limitation on the present application.

[0033] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0034] In this application, unless otherwise clearly specified and limited, the terms "installation", "connection" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0035] It should also be noted that the methods used in this application are all conventional methods unless otherwise specified; the raw materials and devices used are all conventional commercially available products unless otherwise specified.

[0036] This application provides a Figure 1 , 2 The cryotube storage structure shown is installed on the rotating shaft of a rotary cryostat rack, and mainly includes a bracket 2 and a hole plate 1, and the hole plate 1 is installed on the bracket 2.

[0037] Among them, the bracket 2 and the hole plate 1 are both disc-shaped, which conforms to the conventional design of the rotary structure and has better balance. In this embodiment, a through-hole through the hole plate 1 and the bracket 2 is processed at the center, which is used to pass the rotating shaft of the freezing rack, and two symmetrical keyways are processed on the side of the through-hole to cooperate with the key on the rotating shaft, so as to form a better installation and fixing foundation.

[0038] The bracket 2 is connected to the rotating mechanism of the freezing rack; optionally, a retaining ring is provided on the outer side of the bracket 2, and a gear ring 3 is fixedly installed at the lower part of the retaining ring, and the driving gear of the rotating mechanism is meshed with the gear ring 3. As the driving gear rotates, the bracket 2 is driven to rotate, and the hole plate 1 is driven to rotate.

[0039] Optionally, in order to accurately control the rotation angle, a block-shaped limit mechanism 4 is installed on the outer edge of the retaining ring. The limit structure 4 not only limits the rotation angle of the bracket 2, but also cooperates with appropriate angle zeroing operations to regularly calibrate the zero position to ensure the rotation accuracy of the bracket 2.

[0040] like Figure 1 As shown, a long square avoidance groove is provided on the bracket 2 and the well plate 1, and the midline of the long side direction of the avoidance groove is arranged along the radial direction of the well plate 1. The avoidance groove connects the upper part of the well plate 1 and the lower part of the bracket 2 in the vertical direction. This design allows the clamping mechanism to shuttle through the multi-layer stacked freezing racks, thereby clamping the test tubes on the well plate of the specified layer.

[0041] Specifically, each orifice plate 1 is provided with three sector ring areas, such as Figure 1As shown, through holes are closely arranged in each sector ring area for placing test tube-style cryotubes. Furthermore, the avoidance groove is located between the two sector ring areas, and the radial length is greater than the side length of the sector ring area to ensure that the radial movement of the clamping mechanism can cover the radial range of the sector ring area, and cooperate with the rotation of the bracket 2 to clamp any specified cryotube using polar coordinates.

[0042] Furthermore, in each sector ring area, there are multiple circles of through holes in the radial direction, each circle is in the shape of an arc, and the through holes in each circle are evenly distributed along the circumference, and the through holes in two adjacent circles are staggered in the radial direction, so that the interval between the two circles can be reduced to increase the number of circles and design more through hole positions. Since the overall distribution of through holes is fan-shaped, the number of through holes in two adjacent circles in each sector ring area is different, and the difference between the number of through holes in the outer circle and the inner circle in the radial direction is 2. Specifically, Figure 1 Taking the larger sector ring area as an example, the nth circle is provided with 5+2n through holes (n is a positive integer), such as: the first circle near the center area is provided with 7, the second circle is provided with 9, and so on; in the two smaller sector ring areas (sector ring areas on both sides of the avoidance groove), the nth circle is provided with 5+2(n-1) through holes, such as: the first circle near the center area is provided with 5, the second circle is provided with 7, and so on. Through the reasonable arrangement of the holes, a small size and a large storage capacity can be achieved, such as an outer size of less than 700mm, but it can store 1272 2ml cryotubes or 2130 1ml cryotubes.

[0043] Optionally, in order to ensure the stable placement of the cryotubes, the hole tray 1 is designed to be a multi-layer stacked structure. This embodiment uses two stacked hole trays 1 for illustration, which are a first hole tray 101 located on the upper layer and a second hole tray 102 located on the middle layer, and the two hole trays are stacked and installed on the bracket 2 by bolts 5. The through holes of the two layers of hole trays 1 are in the same position, so that the cryotubes can be placed stably. In order to meet different placement requirements, the distance between each layer is designed to have the ability to be quickly adjusted. Combined with Figure 2 As shown, a bolt sleeve 6 is provided between the first hole plate 101 and the second hole plate 102; a bolt sleeve 6 is also provided between the second hole plate 102 and the bracket 2. Further, each group of two bolt sleeves 6 are sleeved on the bolts 5, and are used to separate the first hole plate 101 and the second hole plate 102 and the second hole plate 102 and the bracket 2 respectively. When it is necessary to adjust according to the size of the cryopreservation tube, it is only necessary to replace the corresponding bolts 5 and bolt sleeves 6.

[0044] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present application, rather than to limit the scope of protection of the present application. Simple modifications or equivalent substitutions of the technical solution of the present application by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the present application.

Claims

1. A cryotube storage structure, mounted on a rotating shaft of a rotary cryostat, characterized in that: It comprises a bracket and at least one orifice plate; the orifice plate is mounted on the bracket, and the bracket and / or the orifice plate is connected to a rotary mechanism; At least one avoidance groove is provided on each of the bracket and the orifice plate, and the avoidance groove vertically connects the upper part of the orifice plate and the lower part of the bracket; The perforated plate is provided with a plurality of sector ring areas, each of which is densely packed with through holes for placing cryotubes; The through holes in the sector ring area have a total of multiple circles along the radial direction, and the through holes in each circle are evenly distributed along the circumferential direction; the through holes in two adjacent circles are staggered in the radial direction.

2. The cryotube storage structure according to claim 1, characterized in that: The numbers of two adjacent circles of through holes in each of the sector ring areas are different, and the difference between the number of through holes in an outer circle and the number of through holes in an inner circle along the radial direction is greater than or equal to 2.

3. The cryotube storage structure according to claim 1, characterized in that: The avoidance groove is in a square strip structure, is located between two sector ring areas, and the radial length of the avoidance groove is greater than the side length of the sector ring area.

4. The cryotube storage structure according to claim 1, characterized in that: The orifice plate has two layers, including a first orifice plate and a second orifice plate, and the two orifice plates are stacked and installed on the bracket by bolts.

5. The cryotube storage structure according to claim 4, characterized in that: A bolt sleeve is provided between the first hole plate and the second hole plate; a bolt sleeve is also provided between the second hole plate and the bracket; The bolt sleeve is sleeved on the bolt and is used to separate the orifice plate and the bracket.

6. The cryotube storage structure according to claim 1, characterized in that: The bracket is in the shape of a disk, and a gear ring is provided on the outer side; The ring gear is connected to the rotary mechanism.

7. The cryotube storage structure according to claim 6, characterized in that: The rotary mechanism is provided with a driving gear which is meshed with the gear ring.

8. The cryotube storage structure according to claim 6 or 7, characterized in that: A retaining ring is arranged on the outer side of the bracket, and the gear ring is installed on the outer side or the lower part of the retaining ring.

9. The cryotube storage structure according to claim 8, characterized in that: The retaining ring is also provided with a limiting structure.

10. The cryotube storage structure according to claim 1, characterized in that: The centers of the bracket and the orifice plate are provided with mounting through holes, which are connected to the rotating shaft; At least one keyway is also provided on the peripheral side of the mounting through hole.

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